Click here to switch to the map view.

The map label for this gene is yqgN [H]

Identifier: 229916287

GI number: 229916287

Start: 503501

End: 504055

Strand: Reverse

Name: yqgN [H]

Synonym: EAT1b_0556

Alternate gene names: 229916287

Gene position: 504055-503501 (Counterclockwise)

Preceding gene: 229916288

Following gene: 229916286

Centisome position: 16.8

GC content: 46.31

Gene sequence:

>555_bases
GTGGAAGAAAAAGCAGCGCTCCGGCGCACGATTCATCAATACATCAAACAAATGTCGGAGCGACATCATGCGGACGAAGC
CATTCACCAAACATTGTTTGCCTCGGATTTATGGGTCGAAAGTCAAACGATCGCGCTGACGTTATCACTCCCGCTAGAAA
TCGATACGTCTCCGATTATTCATATGGCCTTTAAAGAAGGAAAAACGGTTTGCGTCCCGAAAGTAACGGAGCAGGGACTT
ACGTTTCACATCATTCATTCATTTGATGATTTAGAAACGGGCGTCATGAATATTTTAGAGCCGATCACTCCAGCGACGAC
GCAAGTGATCGACCTTTGTCTTGTTCCGGGGCGTGTTTTCGATCGAACCGGTTATCGCATCGGTTGGGGTGGAGGCTATT
ATGATCGCTTTTTAGAAACCTATAACGGTAGAACGCTTGCTTTGGCATATACCGTTCAGCTTGTCGATCATGTACCAACT
GAGCCACACGACCTACCTGTTCAATGGATCGTAACAGAAAAGGAGATGATTCAGTGTTCGCCATATTCGCTGTAA

Upstream 100 bases:

>100_bases
CAACCCACGTCTCCGTCGTCACACGCTTTACCGCGAAGTGAAGTAATAAGGGACCGGCCGTCACATATGTGACGGCTTTT
TTCGTAAGGAGGAATGCGTT

Downstream 100 bases:

>100_bases
CATGTTTCGTCGCCTATCTCGGTTATCGGTTACGGTCGTTGACTCGCTCTGGGGCGCTGTTGACAGTCGTGACCGGTACG
GTGATCGGATTCTCGTTCGG

Product: 5-formyltetrahydrofolate cyclo-ligase

Products: ADP; phosphate; 5,10-methenyltetrahydrofolate

Alternate protein names: NA

Number of amino acids: Translated: 184; Mature: 184

Protein sequence:

>184_residues
MEEKAALRRTIHQYIKQMSERHHADEAIHQTLFASDLWVESQTIALTLSLPLEIDTSPIIHMAFKEGKTVCVPKVTEQGL
TFHIIHSFDDLETGVMNILEPITPATTQVIDLCLVPGRVFDRTGYRIGWGGGYYDRFLETYNGRTLALAYTVQLVDHVPT
EPHDLPVQWIVTEKEMIQCSPYSL

Sequences:

>Translated_184_residues
MEEKAALRRTIHQYIKQMSERHHADEAIHQTLFASDLWVESQTIALTLSLPLEIDTSPIIHMAFKEGKTVCVPKVTEQGL
TFHIIHSFDDLETGVMNILEPITPATTQVIDLCLVPGRVFDRTGYRIGWGGGYYDRFLETYNGRTLALAYTVQLVDHVPT
EPHDLPVQWIVTEKEMIQCSPYSL
>Mature_184_residues
MEEKAALRRTIHQYIKQMSERHHADEAIHQTLFASDLWVESQTIALTLSLPLEIDTSPIIHMAFKEGKTVCVPKVTEQGL
TFHIIHSFDDLETGVMNILEPITPATTQVIDLCLVPGRVFDRTGYRIGWGGGYYDRFLETYNGRTLALAYTVQLVDHVPT
EPHDLPVQWIVTEKEMIQCSPYSL

Specific function: Unknown

COG id: COG0212

COG function: function code H; 5-formyltetrahydrofolate cyclo-ligase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 5-formyltetrahydrofolate cyclo-ligase family [H]

Homologues:

Organism=Homo sapiens, GI5453746, Length=189, Percent_Identity=29.1005291005291, Blast_Score=75, Evalue=2e-14,
Organism=Escherichia coli, GI1789278, Length=150, Percent_Identity=31.3333333333333, Blast_Score=71, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI17510857, Length=196, Percent_Identity=27.5510204081633, Blast_Score=75, Evalue=1e-14,
Organism=Drosophila melanogaster, GI161077430, Length=193, Percent_Identity=27.4611398963731, Blast_Score=72, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002698 [H]

Pfam domain/function: PF01812 5-FTHF_cyc-lig [H]

EC number: 6.3.3.2

Molecular weight: Translated: 20952; Mature: 20952

Theoretical pI: Translated: 5.22; Mature: 5.22

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEEKAALRRTIHQYIKQMSERHHADEAIHQTLFASDLWVESQTIALTLSLPLEIDTSPII
CCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHEECCCEEEEEEEECEEECCCCEE
HMAFKEGKTVCVPKVTEQGLTFHIIHSFDDLETGVMNILEPITPATTQVIDLCLVPGRVF
EEEECCCCEEEECCCCCCCCEEEEEECCCHHHHHHHHHHHCCCCHHHHHHHHHHCCCHHH
DRTGYRIGWGGGYYDRFLETYNGRTLALAYTVQLVDHVPTEPHDLPVQWIVTEKEMIQCS
HCCCCEEECCCCHHHHHHHHCCCCEEEEHEEEHHHHCCCCCCCCCCEEEEEEHHHHEECC
PYSL
CCCC
>Mature Secondary Structure
MEEKAALRRTIHQYIKQMSERHHADEAIHQTLFASDLWVESQTIALTLSLPLEIDTSPII
CCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHEECCCEEEEEEEECEEECCCCEE
HMAFKEGKTVCVPKVTEQGLTFHIIHSFDDLETGVMNILEPITPATTQVIDLCLVPGRVF
EEEECCCCEEEECCCCCCCCEEEEEECCCHHHHHHHHHHHCCCCHHHHHHHHHHCCCHHH
DRTGYRIGWGGGYYDRFLETYNGRTLALAYTVQLVDHVPTEPHDLPVQWIVTEKEMIQCS
HCCCCEEECCCCHHHHHHHHCCCCEEEEHEEEHHHHCCCCCCCCCCEEEEEEHHHHEECC
PYSL
CCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; 5-formyltetrahydrofolate

Specific reaction: ATP + 5-formyltetrahydrofolate = ADP + phosphate + 5,10-methenyltetrahydrofolate

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8969508; 9384377 [H]