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The map label for this gene is gcvT [H]

Identifier: 229916267

GI number: 229916267

Start: 488509

End: 489597

Strand: Reverse

Name: gcvT [H]

Synonym: EAT1b_0536

Alternate gene names: 229916267

Gene position: 489597-488509 (Counterclockwise)

Preceding gene: 229916268

Following gene: 229916266

Centisome position: 16.32

GC content: 46.46

Gene sequence:

>1089_bases
TTGGGGGATATTATGGAAAAGGTTACTTTGAAACGTACGCCTTTGTTCGATTTGATTGAACCGAAGGCGAAGATGGTTGA
TTTTGCGGGATTTGAAATGCCGATTATGTTCTCTTCGATTAAAGAAGAGCATTTGGCTGTACGTCAAAACGTGGGGATGT
TTGATGTATCTCACATGGGAGAAATTCGAATCGAAGGGCCGGATGCGCTTGAGCAAGTTCAAAACTTGGTGACGAATGAT
ATCTCGAAGATTAAAGTTGGTCAAGCCCAGTATAACCTTCTCTGTCTTGAAGACGGCGGTGTGGTGGACGATTTGCTTGT
CTATCGATTAGATGAGGACGCTTATTGGCTCGTCGTCAATGCTTCAAATATTGAAAAGGACGAAGCCCACATTCGTCGAT
ACGTCAAGGGTGACGTGGTTGTGACAAATGAATCTGATGAATATGGTCAGATTGCGATTCAAGGACCGAATGCACAATCC
GTACTTCAAACTATCACAAATGTGGCACTCGACGAAATCGGGTTCTTCAAATTCATGAATGGGGACGTGGCGGGTGTGCC
ATCGATCATCTCTAGAAGTGGGTATACTGGGGAAGATGGTTTCGAGATTTATGCTCGAGCAGAAGCGATTTCTGCCATCT
GGGAAGCGCTTGAAGCCGAGGGTGTTACCCCATGTGGGCTGGGCGCACGCGATACATTACGTTTCGAAGCGTGCTTGCCG
CTTTACGGTCATGAGTTGGATGAGTCGGTCACGCCATTCGAAGCGAATCTCAATTTTGCAGTTAAGCTAGATACTGATTT
TGTTGGTAAGGAAGCACTCGTCACTCAAAAAGAGAATATTCCGAATCGATTGATCGGATTGAAATTGCTCGGTCGTGGGA
TTGCCCGCCAAGGGGCGCAAGTTGAATTGGATGGGAATGTAATCGGCGTTGTCACGACCGGTACGATGCCTCCGACTGTA
AATGAATCAATCGCATGGGCACGAGTCGATGCACGTTACAAAGATGAAGAGCGTTTTGTCATCGACATCCGTGGCAAAAA
GATTGAAGCCGAACGCGTACCGACACCTTTCTATAAACGAACGAAATGA

Upstream 100 bases:

>100_bases
TTTTCTTTTTCGCTTTTTTACCTATGCAGAAGGAATAAAAATTGTTAAAGTGGAATGGAAAACGAAAGATTTCAAAAACA
AAAGCATTTTATGTTCGGGA

Downstream 100 bases:

>100_bases
AACAGGGGGATTCAGAATGAACAGAATGGAATTTCGTTATTTACCGATGACCGAACAAGATGAACGAGACATGTTAGAGA
CAATCGGCGTCGATTCAATC

Product: glycine cleavage system T protein

Products: NA

Alternate protein names: Glycine cleavage system T protein [H]

Number of amino acids: Translated: 362; Mature: 361

Protein sequence:

>362_residues
MGDIMEKVTLKRTPLFDLIEPKAKMVDFAGFEMPIMFSSIKEEHLAVRQNVGMFDVSHMGEIRIEGPDALEQVQNLVTND
ISKIKVGQAQYNLLCLEDGGVVDDLLVYRLDEDAYWLVVNASNIEKDEAHIRRYVKGDVVVTNESDEYGQIAIQGPNAQS
VLQTITNVALDEIGFFKFMNGDVAGVPSIISRSGYTGEDGFEIYARAEAISAIWEALEAEGVTPCGLGARDTLRFEACLP
LYGHELDESVTPFEANLNFAVKLDTDFVGKEALVTQKENIPNRLIGLKLLGRGIARQGAQVELDGNVIGVVTTGTMPPTV
NESIAWARVDARYKDEERFVIDIRGKKIEAERVPTPFYKRTK

Sequences:

>Translated_362_residues
MGDIMEKVTLKRTPLFDLIEPKAKMVDFAGFEMPIMFSSIKEEHLAVRQNVGMFDVSHMGEIRIEGPDALEQVQNLVTND
ISKIKVGQAQYNLLCLEDGGVVDDLLVYRLDEDAYWLVVNASNIEKDEAHIRRYVKGDVVVTNESDEYGQIAIQGPNAQS
VLQTITNVALDEIGFFKFMNGDVAGVPSIISRSGYTGEDGFEIYARAEAISAIWEALEAEGVTPCGLGARDTLRFEACLP
LYGHELDESVTPFEANLNFAVKLDTDFVGKEALVTQKENIPNRLIGLKLLGRGIARQGAQVELDGNVIGVVTTGTMPPTV
NESIAWARVDARYKDEERFVIDIRGKKIEAERVPTPFYKRTK
>Mature_361_residues
GDIMEKVTLKRTPLFDLIEPKAKMVDFAGFEMPIMFSSIKEEHLAVRQNVGMFDVSHMGEIRIEGPDALEQVQNLVTNDI
SKIKVGQAQYNLLCLEDGGVVDDLLVYRLDEDAYWLVVNASNIEKDEAHIRRYVKGDVVVTNESDEYGQIAIQGPNAQSV
LQTITNVALDEIGFFKFMNGDVAGVPSIISRSGYTGEDGFEIYARAEAISAIWEALEAEGVTPCGLGARDTLRFEACLPL
YGHELDESVTPFEANLNFAVKLDTDFVGKEALVTQKENIPNRLIGLKLLGRGIARQGAQVELDGNVIGVVTTGTMPPTVN
ESIAWARVDARYKDEERFVIDIRGKKIEAERVPTPFYKRTK

Specific function: The glycine cleavage system catalyzes the degradation of glycine [H]

COG id: COG0404

COG function: function code E; Glycine cleavage system T protein (aminomethyltransferase)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the gcvT family [H]

Homologues:

Organism=Homo sapiens, GI44662838, Length=365, Percent_Identity=33.4246575342466, Blast_Score=181, Evalue=1e-45,
Organism=Homo sapiens, GI257796258, Length=341, Percent_Identity=34.3108504398827, Blast_Score=177, Evalue=1e-44,
Organism=Homo sapiens, GI257796254, Length=364, Percent_Identity=30.2197802197802, Blast_Score=140, Evalue=1e-33,
Organism=Homo sapiens, GI257796256, Length=318, Percent_Identity=31.4465408805031, Blast_Score=134, Evalue=1e-31,
Organism=Homo sapiens, GI24797151, Length=389, Percent_Identity=28.0205655526992, Blast_Score=125, Evalue=7e-29,
Organism=Homo sapiens, GI197927446, Length=332, Percent_Identity=25, Blast_Score=93, Evalue=5e-19,
Organism=Homo sapiens, GI21361378, Length=332, Percent_Identity=25, Blast_Score=93, Evalue=5e-19,
Organism=Homo sapiens, GI194306651, Length=307, Percent_Identity=24.7557003257329, Blast_Score=81, Evalue=1e-15,
Organism=Escherichia coli, GI1789272, Length=364, Percent_Identity=38.7362637362637, Blast_Score=231, Evalue=6e-62,
Organism=Caenorhabditis elegans, GI17560118, Length=354, Percent_Identity=37.0056497175141, Blast_Score=198, Evalue=4e-51,
Organism=Caenorhabditis elegans, GI32563613, Length=340, Percent_Identity=24.4117647058824, Blast_Score=94, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI71994045, Length=340, Percent_Identity=25.5882352941176, Blast_Score=89, Evalue=3e-18,
Organism=Caenorhabditis elegans, GI71994052, Length=340, Percent_Identity=25.5882352941176, Blast_Score=89, Evalue=3e-18,
Organism=Saccharomyces cerevisiae, GI6320222, Length=390, Percent_Identity=33.8461538461538, Blast_Score=174, Evalue=2e-44,
Organism=Drosophila melanogaster, GI20129441, Length=372, Percent_Identity=34.9462365591398, Blast_Score=180, Evalue=1e-45,
Organism=Drosophila melanogaster, GI28571104, Length=279, Percent_Identity=25.089605734767, Blast_Score=89, Evalue=5e-18,
Organism=Drosophila melanogaster, GI20130091, Length=357, Percent_Identity=25.4901960784314, Blast_Score=79, Evalue=6e-15,

Paralogues:

None

Copy number: 40 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013977
- InterPro:   IPR006222
- InterPro:   IPR006223
- InterPro:   IPR022903 [H]

Pfam domain/function: PF01571 GCV_T; PF08669 GCV_T_C [H]

EC number: =2.1.2.10 [H]

Molecular weight: Translated: 40151; Mature: 40020

Theoretical pI: Translated: 4.44; Mature: 4.44

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGDIMEKVTLKRTPLFDLIEPKAKMVDFAGFEMPIMFSSIKEEHLAVRQNVGMFDVSHMG
CCCHHHHHHHCCCCCHHHHCCHHHEEECCCCCCHHHHHHHHHHHHHHHHCCCEEEECCCC
EIRIEGPDALEQVQNLVTNDISKIKVGQAQYNLLCLEDGGVVDDLLVYRLDEDAYWLVVN
EEEECCCHHHHHHHHHHHCCHHHEEECCCEEEEEEEECCCCCCEEEEEEECCCEEEEEEE
ASNIEKDEAHIRRYVKGDVVVTNESDEYGQIAIQGPNAQSVLQTITNVALDEIGFFKFMN
CCCCCHHHHHHHHHHCCCEEEECCCCCCCEEEEECCCHHHHHHHHHHHHHHHCCEEEEEC
GDVAGVPSIISRSGYTGEDGFEIYARAEAISAIWEALEAEGVTPCGLGARDTLRFEACLP
CCCCCCCHHHHCCCCCCCCCEEEEEHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEECC
LYGHELDESVTPFEANLNFAVKLDTDFVGKEALVTQKENIPNRLIGLKLLGRGIARQGAQ
HHCCCCCCCCCCEECCCEEEEEECCCCCCCHHHEECCCCCCHHHHHHHHHHHHHHCCCCE
VELDGNVIGVVTTGTMPPTVNESIAWARVDARYKDEERFVIDIRGKKIEAERVPTPFYKR
EEECCCEEEEEEECCCCCCCCCCEEEEEECCCCCCCCEEEEEECCCEEECCCCCCCCCCC
TK
CC
>Mature Secondary Structure 
GDIMEKVTLKRTPLFDLIEPKAKMVDFAGFEMPIMFSSIKEEHLAVRQNVGMFDVSHMG
CCHHHHHHHCCCCCHHHHCCHHHEEECCCCCCHHHHHHHHHHHHHHHHCCCEEEECCCC
EIRIEGPDALEQVQNLVTNDISKIKVGQAQYNLLCLEDGGVVDDLLVYRLDEDAYWLVVN
EEEECCCHHHHHHHHHHHCCHHHEEECCCEEEEEEEECCCCCCEEEEEEECCCEEEEEEE
ASNIEKDEAHIRRYVKGDVVVTNESDEYGQIAIQGPNAQSVLQTITNVALDEIGFFKFMN
CCCCCHHHHHHHHHHCCCEEEECCCCCCCEEEEECCCHHHHHHHHHHHHHHHCCEEEEEC
GDVAGVPSIISRSGYTGEDGFEIYARAEAISAIWEALEAEGVTPCGLGARDTLRFEACLP
CCCCCCCHHHHCCCCCCCCCEEEEEHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEECC
LYGHELDESVTPFEANLNFAVKLDTDFVGKEALVTQKENIPNRLIGLKLLGRGIARQGAQ
HHCCCCCCCCCCEECCCEEEEEECCCCCCCHHHEECCCCCCHHHHHHHHHHHHHHCCCCE
VELDGNVIGVVTTGTMPPTVNESIAWARVDARYKDEERFVIDIRGKKIEAERVPTPFYKR
EEECCCEEEEEEECCCCCCCCCCEEEEEECCCCCCCCEEEEEECCCEEECCCCCCCCCCC
TK
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA