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The map label for this gene is acr1 [H]

Identifier: 229916082

GI number: 229916082

Start: 314296

End: 315156

Strand: Reverse

Name: acr1 [H]

Synonym: EAT1b_0351

Alternate gene names: 229916082

Gene position: 315156-314296 (Counterclockwise)

Preceding gene: 229916083

Following gene: 229916081

Centisome position: 10.51

GC content: 46.57

Gene sequence:

>861_bases
ATGTATGATTACACGTTACTAGAGAGACTCCTATTCCGATTTCCTTCCTTCGATCATCAGAAAATGAAATCAGAATTAGA
TCGGAAAACGATATTGATTACTGGAGCGAGCTCAGGAATCGGGCAGGCGTTCGCTTTTTTACTAGCGGATACAACCGCAC
ATCTGATTCTCGTTGCCCGTAGAGAATCAGACATGAACGCCATGAAGTCTGAAATCGAAAAGGGGTCAGCCACGGTGACC
GTGTTCCCGGCAGATCTTCGAATTGAGGAGGAACGGAATGGTTTGCTGGCGTATCTCCATCAACTACCGGACGGATTGGA
TGTTCTCGTCAGCAATGCTGGAATCTCCATCAATCGTCCCATCATTGAGTCATTCGATCGATACCATGACTTCACTCGGA
CGATGGCGATCAATTACTTTGCTCCGGTACAATTGATGCTATCGCTCATTCCGTTGCTCGAAAAGAAGAACGGGCAGATC
GTCAATGTGTCGACCATCAATGTGTTACTTCATCCTTTTCCTCACTGGGCGGCCTATCAGGCATCAAAAGCCGCGTTCGA
TACGTGGTTTCGCTCTGCGGGTCCGGAACTCACAATCAAAAATATTTCCACGACGACTCTATATCTACCGCTAGTAAAAA
CTCCGATGATTAAACCGACGCTGGCTTATAAGCATTCACCTGCCATGTCACCGGTACATGTGGCAGAATTGATCGGACAT
GCTTTGTATACGAAACGAACAGTATATAAGCCGTGGTGGTTGTTCCTCGGTCAAGTAACGTCACTTGTTTTCAGAAGACC
GATAGACTGGATGGTCCCTGCATTACTTAAGAGAAAGGAGCGTGACAGTAGGAATGGTTAA

Upstream 100 bases:

>100_bases
GCATTACATGTATACGAGAACAGTAATTTTGCTTCTAAACATACAGATTTATTCAATTCATGATTGTTCTATTGTAAAAA
TCAAAAAAGGTGCTGTCTAT

Downstream 100 bases:

>100_bases
GTTATTGAAAGTCTTGTCGCAGCTCCATTTTCTATCACCATCGAACCTAGGTCGTCTATTCGTCGCAATCCGTCAAAATG
GAATCAACTTGATGCTTCTT

Product: short-chain dehydrogenase/reductase SDR

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 286; Mature: 286

Protein sequence:

>286_residues
MYDYTLLERLLFRFPSFDHQKMKSELDRKTILITGASSGIGQAFAFLLADTTAHLILVARRESDMNAMKSEIEKGSATVT
VFPADLRIEEERNGLLAYLHQLPDGLDVLVSNAGISINRPIIESFDRYHDFTRTMAINYFAPVQLMLSLIPLLEKKNGQI
VNVSTINVLLHPFPHWAAYQASKAAFDTWFRSAGPELTIKNISTTTLYLPLVKTPMIKPTLAYKHSPAMSPVHVAELIGH
ALYTKRTVYKPWWLFLGQVTSLVFRRPIDWMVPALLKRKERDSRNG

Sequences:

>Translated_286_residues
MYDYTLLERLLFRFPSFDHQKMKSELDRKTILITGASSGIGQAFAFLLADTTAHLILVARRESDMNAMKSEIEKGSATVT
VFPADLRIEEERNGLLAYLHQLPDGLDVLVSNAGISINRPIIESFDRYHDFTRTMAINYFAPVQLMLSLIPLLEKKNGQI
VNVSTINVLLHPFPHWAAYQASKAAFDTWFRSAGPELTIKNISTTTLYLPLVKTPMIKPTLAYKHSPAMSPVHVAELIGH
ALYTKRTVYKPWWLFLGQVTSLVFRRPIDWMVPALLKRKERDSRNG
>Mature_286_residues
MYDYTLLERLLFRFPSFDHQKMKSELDRKTILITGASSGIGQAFAFLLADTTAHLILVARRESDMNAMKSEIEKGSATVT
VFPADLRIEEERNGLLAYLHQLPDGLDVLVSNAGISINRPIIESFDRYHDFTRTMAINYFAPVQLMLSLIPLLEKKNGQI
VNVSTINVLLHPFPHWAAYQASKAAFDTWFRSAGPELTIKNISTTTLYLPLVKTPMIKPTLAYKHSPAMSPVHVAELIGH
ALYTKRTVYKPWWLFLGQVTSLVFRRPIDWMVPALLKRKERDSRNG

Specific function: Catalyzes the NADPH-dependent reduction of long chain acyl-CoA to the corresponding aldehyde [H]

COG id: COG1028

COG function: function code IQR; Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI32455239, Length=251, Percent_Identity=30.2788844621514, Blast_Score=90, Evalue=2e-18,
Organism=Homo sapiens, GI5031765, Length=251, Percent_Identity=30.2788844621514, Blast_Score=90, Evalue=2e-18,
Organism=Homo sapiens, GI32483357, Length=195, Percent_Identity=30.2564102564103, Blast_Score=79, Evalue=4e-15,
Organism=Homo sapiens, GI126723191, Length=194, Percent_Identity=29.8969072164948, Blast_Score=78, Evalue=9e-15,
Organism=Homo sapiens, GI5031737, Length=201, Percent_Identity=26.3681592039801, Blast_Score=75, Evalue=1e-13,
Organism=Homo sapiens, GI33667109, Length=214, Percent_Identity=25.7009345794392, Blast_Score=74, Evalue=1e-13,
Organism=Homo sapiens, GI7706318, Length=227, Percent_Identity=28.1938325991189, Blast_Score=71, Evalue=1e-12,
Organism=Homo sapiens, GI20149619, Length=195, Percent_Identity=29.7435897435897, Blast_Score=70, Evalue=2e-12,
Organism=Escherichia coli, GI1789378, Length=178, Percent_Identity=33.1460674157303, Blast_Score=74, Evalue=9e-15,
Organism=Caenorhabditis elegans, GI193204405, Length=169, Percent_Identity=33.7278106508876, Blast_Score=79, Evalue=4e-15,
Organism=Caenorhabditis elegans, GI17562906, Length=176, Percent_Identity=33.5227272727273, Blast_Score=74, Evalue=8e-14,
Organism=Caenorhabditis elegans, GI17538480, Length=201, Percent_Identity=28.3582089552239, Blast_Score=74, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17531453, Length=174, Percent_Identity=34.4827586206897, Blast_Score=74, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17562904, Length=195, Percent_Identity=28.2051282051282, Blast_Score=73, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17551412, Length=201, Percent_Identity=27.8606965174129, Blast_Score=72, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI115534694, Length=195, Percent_Identity=32.8205128205128, Blast_Score=72, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI72000259, Length=185, Percent_Identity=27.5675675675676, Blast_Score=72, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI17562910, Length=191, Percent_Identity=28.7958115183246, Blast_Score=72, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI17559104, Length=198, Percent_Identity=28.2828282828283, Blast_Score=71, Evalue=5e-13,
Organism=Caenorhabditis elegans, GI17562908, Length=183, Percent_Identity=32.2404371584699, Blast_Score=71, Evalue=7e-13,
Organism=Caenorhabditis elegans, GI17560332, Length=203, Percent_Identity=29.064039408867, Blast_Score=70, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI71994604, Length=169, Percent_Identity=30.7692307692308, Blast_Score=69, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17563726, Length=192, Percent_Identity=27.0833333333333, Blast_Score=68, Evalue=6e-12,
Organism=Caenorhabditis elegans, GI17538486, Length=191, Percent_Identity=28.2722513089005, Blast_Score=67, Evalue=8e-12,
Organism=Caenorhabditis elegans, GI17560220, Length=195, Percent_Identity=29.7435897435897, Blast_Score=65, Evalue=3e-11,
Organism=Saccharomyces cerevisiae, GI6323882, Length=253, Percent_Identity=28.4584980237154, Blast_Score=67, Evalue=3e-12,
Organism=Saccharomyces cerevisiae, GI6319635, Length=223, Percent_Identity=28.2511210762332, Blast_Score=64, Evalue=4e-11,
Organism=Drosophila melanogaster, GI21357041, Length=193, Percent_Identity=34.1968911917098, Blast_Score=87, Evalue=9e-18,
Organism=Drosophila melanogaster, GI21358495, Length=248, Percent_Identity=29.8387096774194, Blast_Score=86, Evalue=2e-17,
Organism=Drosophila melanogaster, GI28571526, Length=184, Percent_Identity=35.8695652173913, Blast_Score=83, Evalue=2e-16,
Organism=Drosophila melanogaster, GI24644339, Length=175, Percent_Identity=35.4285714285714, Blast_Score=78, Evalue=6e-15,
Organism=Drosophila melanogaster, GI23397609, Length=170, Percent_Identity=32.9411764705882, Blast_Score=71, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 32503; Mature: 32503

Theoretical pI: Translated: 9.94; Mature: 9.94

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYDYTLLERLLFRFPSFDHQKMKSELDRKTILITGASSGIGQAFAFLLADTTAHLILVAR
CCCHHHHHHHHHHCCCCCHHHHHHHCCCEEEEEEECCCCHHHHHHHHHHHCCEEEEEEEE
RESDMNAMKSEIEKGSATVTVFPADLRIEEERNGLLAYLHQLPDGLDVLVSNAGISINRP
CCCHHHHHHHHHHCCCCEEEEEECCEEEEHHHCHHHHHHHHCCCCHHHHEECCCCEECCH
IIESFDRYHDFTRTMAINYFAPVQLMLSLIPLLEKKNGQIVNVSTINVLLHPFPHWAAYQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEEEEECCCCCHHHHH
ASKAAFDTWFRSAGPELTIKNISTTTLYLPLVKTPMIKPTLAYKHSPAMSPVHVAELIGH
HHHHHHHHHHHCCCCCEEEECCCEEEEEEEHHCCCCCCCHHCCCCCCCCCHHHHHHHHHH
ALYTKRTVYKPWWLFLGQVTSLVFRRPIDWMVPALLKRKERDSRNG
HHHHHCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MYDYTLLERLLFRFPSFDHQKMKSELDRKTILITGASSGIGQAFAFLLADTTAHLILVAR
CCCHHHHHHHHHHCCCCCHHHHHHHCCCEEEEEEECCCCHHHHHHHHHHHCCEEEEEEEE
RESDMNAMKSEIEKGSATVTVFPADLRIEEERNGLLAYLHQLPDGLDVLVSNAGISINRP
CCCHHHHHHHHHHCCCCEEEEEECCEEEEHHHCHHHHHHHHCCCCHHHHEECCCCEECCH
IIESFDRYHDFTRTMAINYFAPVQLMLSLIPLLEKKNGQIVNVSTINVLLHPFPHWAAYQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEEEEECCCCCHHHHH
ASKAAFDTWFRSAGPELTIKNISTTTLYLPLVKTPMIKPTLAYKHSPAMSPVHVAELIGH
HHHHHHHHHHHCCCCCEEEECCCEEEEEEEHHCCCCCCCHHCCCCCCCCCHHHHHHHHHH
ALYTKRTVYKPWWLFLGQVTSLVFRRPIDWMVPALLKRKERDSRNG
HHHHHCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA