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The map label for this gene is lolC [H]

Identifier: 229587058

GI number: 229587058

Start: 1007127

End: 1008377

Strand: Direct

Name: lolC [H]

Synonym: RAF_ORF0981

Alternate gene names: 229587058

Gene position: 1007127-1008377 (Clockwise)

Preceding gene: 229587057

Following gene: 229587059

Centisome position: 78.77

GC content: 31.65

Gene sequence:

>1251_bases
ATGATCAATAACAATTTTATCTTCAAGATAGCTTTCAGATATTTTAGAGCTAAGAAAAACGAAAAGTTTGTTTCTATTAT
TTCTGCCTTTTCTTTAGTAGGCGTCATGATCGGCGTTGCAGCATTGATAGTAGTCATGTCCGTTATGAACGGTTTTCATA
TAGAGCTTACTAAAAATATTATCGGCTTAAATGGGGATATAGTGATAAATCGGCAAGGTGGTAGTATTGATAACTATGAA
GAGATTAAAGCCAAACTCCTAAAACAAGATTATGTAAAACATGTAACATTCATTGCTCACGGTCAAGCTTTGGCTCTTGG
TAAAAGTAATAATAGCGGTGTGCTTGTTAAAGGTATGAAATTAAAGGATCTAAGTATAAGAAATGAAATTTTTAAAAATG
TAAATTTTGGTAGTTTTGATAATTTTCACGGCAAAAACGTAATAGCACTCGGAGAACAATTAGCAAGCAATTTAGGCGTA
ACCGTTGGGGATAAGATTAGATTAATTTCACCGAATAATTCAGTTTCTACCACCTTTGGCAGTATGCCAAGATCAAAAGA
ATTTAAAGTTATAGCAATTTTCAATAGCGGTATGTATGATTATGATTTGACAACGATATTAATGCCGCTTACCGCAGCAC
AAAATTTCTTATCTCTCGGCAACGATATTAATTTAATTGAAATTAATAGTCTAGATCCCGATAAAGCTCTCACATATTCA
CATAAAATACAATCACTCTTAGGTCCAACCCTATATGTATTTAATTGGCAAACCTTAAATTCACAATTTTTAAGTGCTCT
TGCTGTTGAGCGTACAGCTATGTTTACTATTCTATCTTTAATTATTACGGTTGCCGCATTTAATATTATTTCAAGCTTAT
TTATGCTTGTTAAAGATAAAACTTCAGATATTGCAATTCTTAGAACTATGGGAGCAAGCACTAAGCAAATAATGCTTATT
TTTATCTATAACGGAATGTTTATAGGATTACTTGGCACAACACTAGGTGTAATCCTTGGTGTTACCTTTTCTTATAATAT
TCAAACTATCAAGAATTATTTGGAGCGTATAACCGGTACTAAAATTTTCGAGGCAGCTATTTATTTTCTTTATAGTTTAC
CTTCAAAAGTAAGAACTGAGGATATTATTTTAATTACCTCTTTATCTATAATATTGTGTTTTCTTGCGACAATTTATCCT
TCTTATAGAGCCTCAAAATTAAATCCCGTGGATGCCCTAAGATATGAATAA

Upstream 100 bases:

>100_bases
ATTTCATAAGATTGCCACGCAGCCTACGGCTGTTCACAATGACAAAAAAGCTGATTCACACAGTAATAACCTAGAAACGG
ATGTAAGAAAAAATAAACAA

Downstream 100 bases:

>100_bases
TACAGTCCTCATTTTAAAAAATATCTCAAAACATTACAGCCAAGGCAAAATTATTGTTAGAGTACTAGATGATCTTAATC
TAACGGTTAATGAAGGTGAA

Product: Lipoprotein releasing system, transmembrane protein, LolC/E family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 416; Mature: 416

Protein sequence:

>416_residues
MINNNFIFKIAFRYFRAKKNEKFVSIISAFSLVGVMIGVAALIVVMSVMNGFHIELTKNIIGLNGDIVINRQGGSIDNYE
EIKAKLLKQDYVKHVTFIAHGQALALGKSNNSGVLVKGMKLKDLSIRNEIFKNVNFGSFDNFHGKNVIALGEQLASNLGV
TVGDKIRLISPNNSVSTTFGSMPRSKEFKVIAIFNSGMYDYDLTTILMPLTAAQNFLSLGNDINLIEINSLDPDKALTYS
HKIQSLLGPTLYVFNWQTLNSQFLSALAVERTAMFTILSLIITVAAFNIISSLFMLVKDKTSDIAILRTMGASTKQIMLI
FIYNGMFIGLLGTTLGVILGVTFSYNIQTIKNYLERITGTKIFEAAIYFLYSLPSKVRTEDIILITSLSIILCFLATIYP
SYRASKLNPVDALRYE

Sequences:

>Translated_416_residues
MINNNFIFKIAFRYFRAKKNEKFVSIISAFSLVGVMIGVAALIVVMSVMNGFHIELTKNIIGLNGDIVINRQGGSIDNYE
EIKAKLLKQDYVKHVTFIAHGQALALGKSNNSGVLVKGMKLKDLSIRNEIFKNVNFGSFDNFHGKNVIALGEQLASNLGV
TVGDKIRLISPNNSVSTTFGSMPRSKEFKVIAIFNSGMYDYDLTTILMPLTAAQNFLSLGNDINLIEINSLDPDKALTYS
HKIQSLLGPTLYVFNWQTLNSQFLSALAVERTAMFTILSLIITVAAFNIISSLFMLVKDKTSDIAILRTMGASTKQIMLI
FIYNGMFIGLLGTTLGVILGVTFSYNIQTIKNYLERITGTKIFEAAIYFLYSLPSKVRTEDIILITSLSIILCFLATIYP
SYRASKLNPVDALRYE
>Mature_416_residues
MINNNFIFKIAFRYFRAKKNEKFVSIISAFSLVGVMIGVAALIVVMSVMNGFHIELTKNIIGLNGDIVINRQGGSIDNYE
EIKAKLLKQDYVKHVTFIAHGQALALGKSNNSGVLVKGMKLKDLSIRNEIFKNVNFGSFDNFHGKNVIALGEQLASNLGV
TVGDKIRLISPNNSVSTTFGSMPRSKEFKVIAIFNSGMYDYDLTTILMPLTAAQNFLSLGNDINLIEINSLDPDKALTYS
HKIQSLLGPTLYVFNWQTLNSQFLSALAVERTAMFTILSLIITVAAFNIISSLFMLVKDKTSDIAILRTMGASTKQIMLI
FIYNGMFIGLLGTTLGVILGVTFSYNIQTIKNYLERITGTKIFEAAIYFLYSLPSKVRTEDIILITSLSIILCFLATIYP
SYRASKLNPVDALRYE

Specific function: Part of an ATP-dependent transport system responsible for the release of lipoproteins targeted to the outer membrane from the inner membrane. Such a release is dependent of the sorting-signal (absence of an Asp at position 2 of the mature lipoprotein) and

COG id: COG4591

COG function: function code M; ABC-type transport system, involved in lipoprotein release, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily [H]

Homologues:

Organism=Escherichia coli, GI1787360, Length=418, Percent_Identity=33.7320574162679, Blast_Score=176, Evalue=3e-45,
Organism=Escherichia coli, GI1787362, Length=414, Percent_Identity=30.4347826086957, Blast_Score=166, Evalue=3e-42,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003838
- InterPro:   IPR011925 [H]

Pfam domain/function: PF02687 FtsX [H]

EC number: NA

Molecular weight: Translated: 46172; Mature: 46172

Theoretical pI: Translated: 9.92; Mature: 9.92

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MINNNFIFKIAFRYFRAKKNEKFVSIISAFSLVGVMIGVAALIVVMSVMNGFHIELTKNI
CCCCCEEEEHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCE
IGLNGDIVINRQGGSIDNYEEIKAKLLKQDYVKHVTFIAHGQALALGKSNNSGVLVKGMK
ECCCCCEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHEECCCEEEEECCCCCCEEEECCE
LKDLSIRNEIFKNVNFGSFDNFHGKNVIALGEQLASNLGVTVGDKIRLISPNNSVSTTFG
EECHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHCCCEECCEEEEECCCCCCCCHHC
SMPRSKEFKVIAIFNSGMYDYDLTTILMPLTAAQNFLSLGNDINLIEINSLDPDKALTYS
CCCCCCCEEEEEEEECCCCCCCHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCHHHHHH
HKIQSLLGPTLYVFNWQTLNSQFLSALAVERTAMFTILSLIITVAAFNIISSLFMLVKDK
HHHHHHHCCEEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
TSDIAILRTMGASTKQIMLIFIYNGMFIGLLGTTLGVILGVTFSYNIQTIKNYLERITGT
CCCEEEEEECCCCCHHEEEEEEECCHHHHHHHHHHHHHHHHHEECCHHHHHHHHHHHCCC
KIFEAAIYFLYSLPSKVRTEDIILITSLSIILCFLATIYPSYRASKLNPVDALRYE
HHHHHHHHHHHHCCCCCCCCCEEEHHHHHHHHHHHHHHCCCCCCCCCCCCHHCCCC
>Mature Secondary Structure
MINNNFIFKIAFRYFRAKKNEKFVSIISAFSLVGVMIGVAALIVVMSVMNGFHIELTKNI
CCCCCEEEEHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCE
IGLNGDIVINRQGGSIDNYEEIKAKLLKQDYVKHVTFIAHGQALALGKSNNSGVLVKGMK
ECCCCCEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHEECCCEEEEECCCCCCEEEECCE
LKDLSIRNEIFKNVNFGSFDNFHGKNVIALGEQLASNLGVTVGDKIRLISPNNSVSTTFG
EECHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHCCCEECCEEEEECCCCCCCCHHC
SMPRSKEFKVIAIFNSGMYDYDLTTILMPLTAAQNFLSLGNDINLIEINSLDPDKALTYS
CCCCCCCEEEEEEEECCCCCCCHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCHHHHHH
HKIQSLLGPTLYVFNWQTLNSQFLSALAVERTAMFTILSLIITVAAFNIISSLFMLVKDK
HHHHHHHCCEEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
TSDIAILRTMGASTKQIMLIFIYNGMFIGLLGTTLGVILGVTFSYNIQTIKNYLERITGT
CCCEEEEEECCCCCHHEEEEEEECCHHHHHHHHHHHHHHHHHEECCHHHHHHHHHHHCCC
KIFEAAIYFLYSLPSKVRTEDIILITSLSIILCFLATIYPSYRASKLNPVDALRYE
HHHHHHHHHHHHCCCCCCCCCEEEHHHHHHHHHHHHHHCCCCCCCCCCCCHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10761919 [H]