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The map label for this gene is xseA [H]

Identifier: 229587029

GI number: 229587029

Start: 962877

End: 964211

Strand: Direct

Name: xseA [H]

Synonym: RAF_ORF0932

Alternate gene names: 229587029

Gene position: 962877-964211 (Clockwise)

Preceding gene: 229587028

Following gene: 229587030

Centisome position: 75.31

GC content: 32.51

Gene sequence:

>1335_bases
ATGCTAGACAATTTCATTGCGCATCAAACAACCAAAGAGTTTTCAGTTAGTGAGATTTCTAATAAAATCAAAGAGCTATT
AGAAAATAATTTTGGCTATATTAAGGTAAAAGGCGAAATTTCAGGCTTAAAAATAGCAAACTCAGGTCATGCTTATTTTA
ACTTAAAAGAAAATACCGCCATTTTAGCCTGTACTTGCTGGCGTCCTATTCTTGCTAAAATCAAATTTCCTTTAAATGAC
GGCATGGAAGTAGTAATTAGCGGTAAACTCTCAAGTTATGCAGGTAATTCACGTTATCAATTATCGGTAGATAATTTGCA
ACCCACAGGACTTGGAGCTATGCTGCAAATTCTAAATGAGCGTAAAGCAAGGCTCGAGAAAGAAGGCTTATTTAATAAAA
TACGTATTCCTATACCCTTTTTACCTGATAAAATAGGCGTTATCACTTCAATAACCGGTGCTGTTATTAAAGATATTATT
CATCGTATTCGCGAACGTTTTCCGACTCGGATAATAATATGGCCAGTTAGCGTACAAGGCGAAAATTCTGGCAATGAAAT
TGCTGAAGCAATTGAAGGATTTAACAATTTAGAAGAGGTAAATAAACCACGTGTTATAATCGTTGCTAGAGGTGGCGGTT
CTATAGAAGATCTTTGGTCATTTAACGATGAGATATTAGTACGTGCTGCTTATAACTCAAAAATTCCTATTATTTCCGCA
GTAGGTCATGAAGTGGATTATACTTTAATAGATTTAGCAGCTGATAAAAGAGCTCCAACACCGACTGCTGCCGCAGAATT
TGCTGTACCGGTACACTCTATTTTAAATAATACGCTACAATCTTATGAAAAAATATTATTGAATAATACTAGCCGGTTAA
TTAAATATCACGAACAAAATATAGTAAATTACAATAAAATACACAGATATCTCTCTCACTATATAAATCATAGGCAGCAG
TTACTGGACGAAACCGGTTTTAATTTACTAGATGCTTTACCGTGCTTTATTGAACTACAAGAAACAAAGATAAAATCTTT
TTCTAAAGAAAGAGTTAACCCTGCTAAAATAATCAATTACAAAACATTAGAATTAACACATCAAACAGCTTATCTATCAA
AATCGGCAAATAATACTTTGAAAAACTTTGAGTATAAATTAGAATTAAATAGTACGTTACTTGCAAGCCTTGATTATCAC
AACGTATTAAAACGAGGTTTTGCTATAGTTAAAGGAGAAACGGGTAATTTTTTATCTTCTAAAATTACTGCTGCGAATGA
AAAAATTTTTAATATTAAATTTTCTGACGGTGAAATTAAAGTAGTTCGTGCTTAA

Upstream 100 bases:

>100_bases
GAAGTAGGATAAACTCCTGAGATTGCTTCGTCACAATAGTTTCTCCTCGTAATGACGAATAATGTGTTACCCTCAGCACA
AAAAACCAAGTACTAATAAA

Downstream 100 bases:

>100_bases
AGGCTTTGGTTTTTATACTTCTCATTTCTAAAAATTTGTATGCTTTAAGCATATGCACGAACGAACAACAAGCAATTTTA
GAATGCGAAGGGACAGCTGA

Product: exodeoxyribonuclease VII large subunit

Products: NA

Alternate protein names: Exodeoxyribonuclease VII large subunit; Exonuclease VII large subunit [H]

Number of amino acids: Translated: 444; Mature: 444

Protein sequence:

>444_residues
MLDNFIAHQTTKEFSVSEISNKIKELLENNFGYIKVKGEISGLKIANSGHAYFNLKENTAILACTCWRPILAKIKFPLND
GMEVVISGKLSSYAGNSRYQLSVDNLQPTGLGAMLQILNERKARLEKEGLFNKIRIPIPFLPDKIGVITSITGAVIKDII
HRIRERFPTRIIIWPVSVQGENSGNEIAEAIEGFNNLEEVNKPRVIIVARGGGSIEDLWSFNDEILVRAAYNSKIPIISA
VGHEVDYTLIDLAADKRAPTPTAAAEFAVPVHSILNNTLQSYEKILLNNTSRLIKYHEQNIVNYNKIHRYLSHYINHRQQ
LLDETGFNLLDALPCFIELQETKIKSFSKERVNPAKIINYKTLELTHQTAYLSKSANNTLKNFEYKLELNSTLLASLDYH
NVLKRGFAIVKGETGNFLSSKITAANEKIFNIKFSDGEIKVVRA

Sequences:

>Translated_444_residues
MLDNFIAHQTTKEFSVSEISNKIKELLENNFGYIKVKGEISGLKIANSGHAYFNLKENTAILACTCWRPILAKIKFPLND
GMEVVISGKLSSYAGNSRYQLSVDNLQPTGLGAMLQILNERKARLEKEGLFNKIRIPIPFLPDKIGVITSITGAVIKDII
HRIRERFPTRIIIWPVSVQGENSGNEIAEAIEGFNNLEEVNKPRVIIVARGGGSIEDLWSFNDEILVRAAYNSKIPIISA
VGHEVDYTLIDLAADKRAPTPTAAAEFAVPVHSILNNTLQSYEKILLNNTSRLIKYHEQNIVNYNKIHRYLSHYINHRQQ
LLDETGFNLLDALPCFIELQETKIKSFSKERVNPAKIINYKTLELTHQTAYLSKSANNTLKNFEYKLELNSTLLASLDYH
NVLKRGFAIVKGETGNFLSSKITAANEKIFNIKFSDGEIKVVRA
>Mature_444_residues
MLDNFIAHQTTKEFSVSEISNKIKELLENNFGYIKVKGEISGLKIANSGHAYFNLKENTAILACTCWRPILAKIKFPLND
GMEVVISGKLSSYAGNSRYQLSVDNLQPTGLGAMLQILNERKARLEKEGLFNKIRIPIPFLPDKIGVITSITGAVIKDII
HRIRERFPTRIIIWPVSVQGENSGNEIAEAIEGFNNLEEVNKPRVIIVARGGGSIEDLWSFNDEILVRAAYNSKIPIISA
VGHEVDYTLIDLAADKRAPTPTAAAEFAVPVHSILNNTLQSYEKILLNNTSRLIKYHEQNIVNYNKIHRYLSHYINHRQQ
LLDETGFNLLDALPCFIELQETKIKSFSKERVNPAKIINYKTLELTHQTAYLSKSANNTLKNFEYKLELNSTLLASLDYH
NVLKRGFAIVKGETGNFLSSKITAANEKIFNIKFSDGEIKVVRA

Specific function: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides [H]

COG id: COG1570

COG function: function code L; Exonuclease VII, large subunit

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the xseA family [H]

Homologues:

Organism=Escherichia coli, GI1788856, Length=446, Percent_Identity=31.6143497757848, Blast_Score=228, Evalue=7e-61,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003753
- InterPro:   IPR020579
- InterPro:   IPR004365 [H]

Pfam domain/function: PF02601 Exonuc_VII_L; PF01336 tRNA_anti [H]

EC number: =3.1.11.6 [H]

Molecular weight: Translated: 49958; Mature: 49958

Theoretical pI: Translated: 9.36; Mature: 9.36

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLDNFIAHQTTKEFSVSEISNKIKELLENNFGYIKVKGEISGLKIANSGHAYFNLKENTA
CCCCHHHHCCCCCCCHHHHHHHHHHHHHCCCCEEEEEECCCCEEEECCCCEEEEEECCCE
ILACTCWRPILAKIKFPLNDGMEVVISGKLSSYAGNSRYQLSVDNLQPTGLGAMLQILNE
EEEEECHHHHHHHEECCCCCCCEEEEECCHHHCCCCCEEEEEECCCCCCCHHHHHHHHHH
RKARLEKEGLFNKIRIPIPFLPDKIGVITSITGAVIKDIIHRIRERFPTRIIIWPVSVQG
HHHHHHHHCCCCEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEEECC
ENSGNEIAEAIEGFNNLEEVNKPRVIIVARGGGSIEDLWSFNDEILVRAAYNSKIPIISA
CCCCHHHHHHHHCCHHHHHCCCCEEEEEECCCCCHHHHHCCCCEEEEEEECCCCCCEEEE
VGHEVDYTLIDLAADKRAPTPTAAAEFAVPVHSILNNTLQSYEKILLNNTSRLIKYHEQN
CCCCCCEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHC
IVNYNKIHRYLSHYINHRQQLLDETGFNLLDALPCFIELQETKIKSFSKERVNPAKIINY
CCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCHHHEEEHHHHHHHHHHHCCCHHHEEEE
KTLELTHQTAYLSKSANNTLKNFEYKLELNSTLLASLDYHNVLKRGFAIVKGETGNFLSS
EEEEEEHHHHHHHCCCCCCHHCEEEEEEECCEEEEECCHHHHHHCCEEEEECCCCCHHHH
KITAANEKIFNIKFSDGEIKVVRA
HHEECCCEEEEEEECCCCEEEEEC
>Mature Secondary Structure
MLDNFIAHQTTKEFSVSEISNKIKELLENNFGYIKVKGEISGLKIANSGHAYFNLKENTA
CCCCHHHHCCCCCCCHHHHHHHHHHHHHCCCCEEEEEECCCCEEEECCCCEEEEEECCCE
ILACTCWRPILAKIKFPLNDGMEVVISGKLSSYAGNSRYQLSVDNLQPTGLGAMLQILNE
EEEEECHHHHHHHEECCCCCCCEEEEECCHHHCCCCCEEEEEECCCCCCCHHHHHHHHHH
RKARLEKEGLFNKIRIPIPFLPDKIGVITSITGAVIKDIIHRIRERFPTRIIIWPVSVQG
HHHHHHHHCCCCEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEEECC
ENSGNEIAEAIEGFNNLEEVNKPRVIIVARGGGSIEDLWSFNDEILVRAAYNSKIPIISA
CCCCHHHHHHHHCCHHHHHCCCCEEEEEECCCCCHHHHHCCCCEEEEEEECCCCCCEEEE
VGHEVDYTLIDLAADKRAPTPTAAAEFAVPVHSILNNTLQSYEKILLNNTSRLIKYHEQN
CCCCCCEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHC
IVNYNKIHRYLSHYINHRQQLLDETGFNLLDALPCFIELQETKIKSFSKERVNPAKIINY
CCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCHHHEEEHHHHHHHHHHHCCCHHHEEEE
KTLELTHQTAYLSKSANNTLKNFEYKLELNSTLLASLDYHNVLKRGFAIVKGETGNFLSS
EEEEEEHHHHHHHCCCCCCHHCEEEEEEECCEEEEECCHHHHHHCCEEEEECCCCCHHHH
KITAANEKIFNIKFSDGEIKVVRA
HHEECCCEEEEEEECCCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA