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The map label for this gene is ileS

Identifier: 229586962

GI number: 229586962

Start: 899989

End: 903267

Strand: Direct

Name: ileS

Synonym: RAF_ORF0859

Alternate gene names: 229586962

Gene position: 899989-903267 (Clockwise)

Preceding gene: 229586961

Following gene: 229586963

Centisome position: 70.39

GC content: 37.08

Gene sequence:

>3279_bases
ATGACAAATACTAAATATTATCCTGAAGTTAACTCGAATGCTGATTTTGCAGGCTTAGAGCGAGAGATACTAAAATTTTG
GCAAGACAATAATATATTCCAAAAATCTATTGATGATAGGAACGGAGAGTTAGAATTTATTTTTTATGACGGCCCGCCTT
TTGCAAACGGTTTGCCGCATTACGGTCATTTGCTTACCGGCTTTATTAAAGACGTATATGCTAGATACCAAACCATAAAA
GGTAAGAAAGTCGAGCGTCGCTTTGGTTGGGACTGTCACGGTCTTCCTGCTGAAATGCAATCAGAGAAAGAACTTGGCAT
TTCAGGACGTCTTGCAATAGCTAATTTTGGTATAGAGAAGTTTAATGCACATTGCAGAGCTTCGGTAATGAAATATGCTA
ATGATTGGGAAGAATATGTAACTCGTCAAGCAAGATGGGTGAATTTTAAAAATTCTTATAAAACGATGGATAAGAATTTT
ATGGAATCCGTACTTTGGGCATTTAAGGAGTTATATAATAAGGGGTTATTGTATGAATCTATGCGGGTAATGCCTTATTC
TTGGGCATGCGAAACACCGCTTTCTAATTTTGAAACAAGACTTGATAATTCTTATCGTGAGCGAGCCGATAAAGCTGTAA
CGGTGAGTTTTGTACTATCTCATCCCGTGGCTACGACCACAGGATCTTTTAAAGAATACCGTATACTCGCTTGGACAACA
ACACCTTGGACATTACCGTCAAATTTAGCCTTAGCAGTCGGTAGTGATATAGATTATGCATTAGTCCCTAAAAATGATGT
TTGTTATATAATAGCTGCCTATTCCGTCTCTAAATATGCTAAAGAATTAGGACTTAGCGGTGAAGAAAATTTTGAGATAA
TTAAAGGCTCAGCACTTCAAGGATTGAACTATAAATCTTTATTCGACTATTTCGAGAATCATCCAAACAGCTTCAAGATA
TTTGCAGGCGACTTCGTGGTTGAGGGTGACGGCACGGGAGTCGTACATATGGCTCCAGGTTTTGGCGAAGATGACCAAAT
ACTTTGTGAATCGAAAGGTATTGAGCTTGTTTGTCCTGTTGATAATAGCGGTAAATTCACTAAAGAAATTCCTGATTTAG
AAGGCTTACAAGTATTTGATGCAAATGACAAAATAATAATCAAACTGAAAGAGCAAGGAAATTGGCTAAAAACCGAGCAG
TATATTCATAATTATCCTCATTGCTGGCGAACAGATACGCCTCTTATATATAAGGCTGTTCCGTCATGGTACGTAAAGGT
TACGCAATTTAAAGATAGAATGGTAGAGTTAAATCAGCAAATTAACTGGATACCTTTCCATGTTAAAGATAATTTATTTG
GTAAGTGGCTTGAAAATGCCCGTGATTGGTCGATAAGCCGTAATAGATTCTGGGGAACGCCGCTGCCTGTATGGAAGTCC
GATGATCCAAAATATCCACGCATAGACGTTTACGGTTCTATAGAGGAATTAGAGAAAGATTTTGGTGTTAAAGTTACTGA
TTTACATCGTCCGTTTATCGATGAACTGACAAGACCAAATCCCGACGATCCAACCGGTAAATCAACAATGCGTAGAATAG
AAGACGTGTTTGATTGCTGGTTTGAAAGCGGTTCAATGCCCTATGGGCAAGCCCATTACCCTTTTGAAAATAAAGAGTGG
TTTGAGGATCATTTTCCGGCTGATTTTATAGTTGAGTATTCAGCTCAAACACGCGGATGGTTTTATACTTTAATGGTGCT
ATCTACCGCTTTATTTGATCGCCCACCGTTTTTAAATTGTATATGCCACGGCATCATTTTAGACTCTACAGGTCAAAAAC
TTTCAAAGCGTCTTAATAACTACGCCGATCCGCTGGAGCTATTTGATAAATACGGCTCTGACGCTTTAAGAGTTACGATG
TTATCTTCAAACGTTGTTAAAGGTCAGGAGCTATTAATTGATAAAGACGGCAAAATGGTATTTGATACGCTTCGTCTATT
TATCAAACCTATATGGAATGCTTACCATTTCTTTACGATGTATGCTAATACCGATTCGCTTAAAGGCAAGCTTAATTTTA
GCTCTAAAAACGTACTTGATGTTTATATATTATCTAAGCTTAAAATAGCCGTACAAAAAATTGAAGAGAGCTTAGATAAT
TTCGATACGCAAACAGCTTATCATGCAGTTTCAGAATTTTTTGAAGTTTTGAATAACTGGTATATAAGACGAAGCCGAGC
TAGATTTTGGAAAAGCGAAAAAGATACAGATAAGCAAAATGCTTATAATACTCTATATTCATGTTTAGACACCATGGCTA
TTGCGATGTCGGCACTAGTGCCTATGATTTCGGAAGCGATATATAAGGGATTACATCATTGTGAGGAGCGTAACGACACG
GCACTCTCAGGAAAATCAAACGTCATTGTGAGGAAAGACACAAGTCTTGACAAAGCAATTTCAGGAGTATCTCATAAGAT
TGCCACGGCACTTTCAGTGCCTTGCAATGACGCGATTAGCGTACATCTCTGCAACTACCCTACTCTCTCAGACTTTGAAA
TAAATCACGAGCTGGTTGCTACTATGGATAACGTGCTTGATATTTGCAGTAATAGCCTATTTATCCGAAGCACTGAAAAT
ATCAGGGTAAGGCAACCACTTGCTAGCATAGCTATTATCAGTAAACATAATAACAACCTCAAAGATTTTGAAGATTTAAT
TAAAGATGAAATTAATGTTAAGGCAGTAATTTATCGTGACGATCTAGAGAATTACGCAAGCAAAAAACTATCGATTAATT
TCCCAATGCTTGGTAAACGTTTGCCGCATAAAATGAAAGAGATTATAGCCGCTTCTAAAAAAGGTGAGTGGGAAGCTATC
GCAGGCGGTTTAGCTATATGCGGTGAAACCTTAAATAGTGACGAATATAAGCTAGTTTTAGAGCCGTATTCACATATCAA
AGGAGCAGCAAGTTTTGAGAATAATAGTAGCTTGTTAATACTTGATTTAGAGCTAACACCTGAGTTAATAGAAGAAGGAT
ACGCAAGAGACATTGTACGCTTTATACAACAGGCTCGAAAAGATGCCGATTTCTCTATCACTGACAGGATTTTAATTGAG
ATAATAAGCGAGTTTAATTTATCTAAGATAATTGATAATTATGGAGACTTTATTAAAGAACAAACTTTAGGCGAGTTTGC
TAAAAATTTCACGCCTGATTATGTAAGTAAAGTAGAATTAGAGAACCATCAAATACAACTTAAAGTTAAGAAATCGTAA

Upstream 100 bases:

>100_bases
TGTAATACACCTTATTACTTTCTTAAATACCTTAAAAATTCTTGTATTATGACCGCTCTTGCATATAATAAAGATATTTT
TAAAAATAATTTCTAAAATA

Downstream 100 bases:

>100_bases
ATTATTTTACTATCAATTAAGATGTTGATAATTTACTTAGATTAATCTATAGTACGCACGCTATAAATTAATTTAAGGTA
AATTATCATGCACAACTCCT

Product: isoleucyl-tRNA synthetase

Products: NA

Alternate protein names: Isoleucine--tRNA ligase; IleRS

Number of amino acids: Translated: 1092; Mature: 1091

Protein sequence:

>1092_residues
MTNTKYYPEVNSNADFAGLEREILKFWQDNNIFQKSIDDRNGELEFIFYDGPPFANGLPHYGHLLTGFIKDVYARYQTIK
GKKVERRFGWDCHGLPAEMQSEKELGISGRLAIANFGIEKFNAHCRASVMKYANDWEEYVTRQARWVNFKNSYKTMDKNF
MESVLWAFKELYNKGLLYESMRVMPYSWACETPLSNFETRLDNSYRERADKAVTVSFVLSHPVATTTGSFKEYRILAWTT
TPWTLPSNLALAVGSDIDYALVPKNDVCYIIAAYSVSKYAKELGLSGEENFEIIKGSALQGLNYKSLFDYFENHPNSFKI
FAGDFVVEGDGTGVVHMAPGFGEDDQILCESKGIELVCPVDNSGKFTKEIPDLEGLQVFDANDKIIIKLKEQGNWLKTEQ
YIHNYPHCWRTDTPLIYKAVPSWYVKVTQFKDRMVELNQQINWIPFHVKDNLFGKWLENARDWSISRNRFWGTPLPVWKS
DDPKYPRIDVYGSIEELEKDFGVKVTDLHRPFIDELTRPNPDDPTGKSTMRRIEDVFDCWFESGSMPYGQAHYPFENKEW
FEDHFPADFIVEYSAQTRGWFYTLMVLSTALFDRPPFLNCICHGIILDSTGQKLSKRLNNYADPLELFDKYGSDALRVTM
LSSNVVKGQELLIDKDGKMVFDTLRLFIKPIWNAYHFFTMYANTDSLKGKLNFSSKNVLDVYILSKLKIAVQKIEESLDN
FDTQTAYHAVSEFFEVLNNWYIRRSRARFWKSEKDTDKQNAYNTLYSCLDTMAIAMSALVPMISEAIYKGLHHCEERNDT
ALSGKSNVIVRKDTSLDKAISGVSHKIATALSVPCNDAISVHLCNYPTLSDFEINHELVATMDNVLDICSNSLFIRSTEN
IRVRQPLASIAIISKHNNNLKDFEDLIKDEINVKAVIYRDDLENYASKKLSINFPMLGKRLPHKMKEIIAASKKGEWEAI
AGGLAICGETLNSDEYKLVLEPYSHIKGAASFENNSSLLILDLELTPELIEEGYARDIVRFIQQARKDADFSITDRILIE
IISEFNLSKIIDNYGDFIKEQTLGEFAKNFTPDYVSKVELENHQIQLKVKKS

Sequences:

>Translated_1092_residues
MTNTKYYPEVNSNADFAGLEREILKFWQDNNIFQKSIDDRNGELEFIFYDGPPFANGLPHYGHLLTGFIKDVYARYQTIK
GKKVERRFGWDCHGLPAEMQSEKELGISGRLAIANFGIEKFNAHCRASVMKYANDWEEYVTRQARWVNFKNSYKTMDKNF
MESVLWAFKELYNKGLLYESMRVMPYSWACETPLSNFETRLDNSYRERADKAVTVSFVLSHPVATTTGSFKEYRILAWTT
TPWTLPSNLALAVGSDIDYALVPKNDVCYIIAAYSVSKYAKELGLSGEENFEIIKGSALQGLNYKSLFDYFENHPNSFKI
FAGDFVVEGDGTGVVHMAPGFGEDDQILCESKGIELVCPVDNSGKFTKEIPDLEGLQVFDANDKIIIKLKEQGNWLKTEQ
YIHNYPHCWRTDTPLIYKAVPSWYVKVTQFKDRMVELNQQINWIPFHVKDNLFGKWLENARDWSISRNRFWGTPLPVWKS
DDPKYPRIDVYGSIEELEKDFGVKVTDLHRPFIDELTRPNPDDPTGKSTMRRIEDVFDCWFESGSMPYGQAHYPFENKEW
FEDHFPADFIVEYSAQTRGWFYTLMVLSTALFDRPPFLNCICHGIILDSTGQKLSKRLNNYADPLELFDKYGSDALRVTM
LSSNVVKGQELLIDKDGKMVFDTLRLFIKPIWNAYHFFTMYANTDSLKGKLNFSSKNVLDVYILSKLKIAVQKIEESLDN
FDTQTAYHAVSEFFEVLNNWYIRRSRARFWKSEKDTDKQNAYNTLYSCLDTMAIAMSALVPMISEAIYKGLHHCEERNDT
ALSGKSNVIVRKDTSLDKAISGVSHKIATALSVPCNDAISVHLCNYPTLSDFEINHELVATMDNVLDICSNSLFIRSTEN
IRVRQPLASIAIISKHNNNLKDFEDLIKDEINVKAVIYRDDLENYASKKLSINFPMLGKRLPHKMKEIIAASKKGEWEAI
AGGLAICGETLNSDEYKLVLEPYSHIKGAASFENNSSLLILDLELTPELIEEGYARDIVRFIQQARKDADFSITDRILIE
IISEFNLSKIIDNYGDFIKEQTLGEFAKNFTPDYVSKVELENHQIQLKVKKS
>Mature_1091_residues
TNTKYYPEVNSNADFAGLEREILKFWQDNNIFQKSIDDRNGELEFIFYDGPPFANGLPHYGHLLTGFIKDVYARYQTIKG
KKVERRFGWDCHGLPAEMQSEKELGISGRLAIANFGIEKFNAHCRASVMKYANDWEEYVTRQARWVNFKNSYKTMDKNFM
ESVLWAFKELYNKGLLYESMRVMPYSWACETPLSNFETRLDNSYRERADKAVTVSFVLSHPVATTTGSFKEYRILAWTTT
PWTLPSNLALAVGSDIDYALVPKNDVCYIIAAYSVSKYAKELGLSGEENFEIIKGSALQGLNYKSLFDYFENHPNSFKIF
AGDFVVEGDGTGVVHMAPGFGEDDQILCESKGIELVCPVDNSGKFTKEIPDLEGLQVFDANDKIIIKLKEQGNWLKTEQY
IHNYPHCWRTDTPLIYKAVPSWYVKVTQFKDRMVELNQQINWIPFHVKDNLFGKWLENARDWSISRNRFWGTPLPVWKSD
DPKYPRIDVYGSIEELEKDFGVKVTDLHRPFIDELTRPNPDDPTGKSTMRRIEDVFDCWFESGSMPYGQAHYPFENKEWF
EDHFPADFIVEYSAQTRGWFYTLMVLSTALFDRPPFLNCICHGIILDSTGQKLSKRLNNYADPLELFDKYGSDALRVTML
SSNVVKGQELLIDKDGKMVFDTLRLFIKPIWNAYHFFTMYANTDSLKGKLNFSSKNVLDVYILSKLKIAVQKIEESLDNF
DTQTAYHAVSEFFEVLNNWYIRRSRARFWKSEKDTDKQNAYNTLYSCLDTMAIAMSALVPMISEAIYKGLHHCEERNDTA
LSGKSNVIVRKDTSLDKAISGVSHKIATALSVPCNDAISVHLCNYPTLSDFEINHELVATMDNVLDICSNSLFIRSTENI
RVRQPLASIAIISKHNNNLKDFEDLIKDEINVKAVIYRDDLENYASKKLSINFPMLGKRLPHKMKEIIAASKKGEWEAIA
GGLAICGETLNSDEYKLVLEPYSHIKGAASFENNSSLLILDLELTPELIEEGYARDIVRFIQQARKDADFSITDRILIEI
ISEFNLSKIIDNYGDFIKEQTLGEFAKNFTPDYVSKVELENHQIQLKVKKS

Specific function: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activi

COG id: COG0060

COG function: function code J; Isoleucyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily

Homologues:

Organism=Homo sapiens, GI94721239, Length=1085, Percent_Identity=38.4331797235023, Blast_Score=751, Evalue=0.0,
Organism=Homo sapiens, GI94721241, Length=1085, Percent_Identity=38.4331797235023, Blast_Score=751, Evalue=0.0,
Organism=Homo sapiens, GI46852147, Length=831, Percent_Identity=27.3164861612515, Blast_Score=280, Evalue=7e-75,
Organism=Homo sapiens, GI5454158, Length=850, Percent_Identity=22.5882352941176, Blast_Score=153, Evalue=7e-37,
Organism=Homo sapiens, GI268370297, Length=815, Percent_Identity=22.9447852760736, Blast_Score=153, Evalue=9e-37,
Organism=Homo sapiens, GI268370295, Length=796, Percent_Identity=22.9899497487437, Blast_Score=153, Evalue=9e-37,
Organism=Homo sapiens, GI268370293, Length=815, Percent_Identity=22.9447852760736, Blast_Score=153, Evalue=9e-37,
Organism=Escherichia coli, GI2367096, Length=793, Percent_Identity=27.2383354350567, Blast_Score=311, Evalue=2e-85,
Organism=Escherichia coli, GI1790708, Length=827, Percent_Identity=21.8863361547763, Blast_Score=136, Evalue=8e-33,
Organism=Caenorhabditis elegans, GI17541896, Length=1074, Percent_Identity=39.0130353817505, Blast_Score=731, Evalue=0.0,
Organism=Caenorhabditis elegans, GI71980946, Length=791, Percent_Identity=25.6637168141593, Blast_Score=228, Evalue=9e-60,
Organism=Caenorhabditis elegans, GI17510661, Length=838, Percent_Identity=22.4343675417661, Blast_Score=167, Evalue=3e-41,
Organism=Caenorhabditis elegans, GI72001587, Length=802, Percent_Identity=22.9426433915212, Blast_Score=144, Evalue=3e-34,
Organism=Saccharomyces cerevisiae, GI6319395, Length=1093, Percent_Identity=37.6944190301921, Blast_Score=709, Evalue=0.0,
Organism=Saccharomyces cerevisiae, GI6325217, Length=644, Percent_Identity=30.2795031055901, Blast_Score=246, Evalue=1e-65,
Organism=Saccharomyces cerevisiae, GI6321531, Length=795, Percent_Identity=23.7735849056604, Blast_Score=179, Evalue=2e-45,
Organism=Drosophila melanogaster, GI28574730, Length=1110, Percent_Identity=37.7477477477477, Blast_Score=723, Evalue=0.0,
Organism=Drosophila melanogaster, GI24668547, Length=1110, Percent_Identity=37.7477477477477, Blast_Score=723, Evalue=0.0,
Organism=Drosophila melanogaster, GI24668543, Length=1110, Percent_Identity=37.7477477477477, Blast_Score=723, Evalue=0.0,
Organism=Drosophila melanogaster, GI281366294, Length=797, Percent_Identity=25.5959849435383, Blast_Score=234, Evalue=3e-61,
Organism=Drosophila melanogaster, GI17864482, Length=851, Percent_Identity=22.9142185663925, Blast_Score=168, Evalue=2e-41,
Organism=Drosophila melanogaster, GI24653289, Length=851, Percent_Identity=22.9142185663925, Blast_Score=168, Evalue=2e-41,
Organism=Drosophila melanogaster, GI21355675, Length=871, Percent_Identity=21.239954075775, Blast_Score=139, Evalue=1e-32,

Paralogues:

None

Copy number: 2,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): SYI_RICAE (C3PP60)

Other databases:

- EMBL:   CP001612
- RefSeq:   YP_002845463.1
- ProteinModelPortal:   C3PP60
- GeneID:   7814858
- GenomeReviews:   CP001612_GR
- KEGG:   raf:RAF_ORF0859
- OMA:   DCHGLPA
- ProtClustDB:   PRK06039
- GO:   GO:0005737
- HAMAP:   MF_02003
- InterPro:   IPR001412
- InterPro:   IPR002300
- InterPro:   IPR002301
- InterPro:   IPR014729
- InterPro:   IPR009080
- InterPro:   IPR013155
- InterPro:   IPR009008
- Gene3D:   G3DSA:3.40.50.620
- PANTHER:   PTHR11946:SF9
- PRINTS:   PR00984
- TIGRFAMs:   TIGR00392

Pfam domain/function: PF08264 Anticodon_1; PF00133 tRNA-synt_1; SSF47323 tRNAsyn_1a_bind; SSF50677 ValRS_IleRS_edit

EC number: =6.1.1.5

Molecular weight: Translated: 125495; Mature: 125363

Theoretical pI: Translated: 5.67; Mature: 5.67

Prosite motif: PS00178 AA_TRNA_LIGASE_I

Important sites: BINDING 616-616

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTNTKYYPEVNSNADFAGLEREILKFWQDNNIFQKSIDDRNGELEFIFYDGPPFANGLPH
CCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCHHHHHCCCCCCCEEEEEECCCCCCCCCCH
YGHLLTGFIKDVYARYQTIKGKKVERRFGWDCHGLPAEMQSEKELGISGRLAIANFGIEK
HHHHHHHHHHHHHHHHHHCCCCHHHHHCCCCCCCCCHHHCCCCCCCCCCEEEEEECCHHH
FNAHCRASVMKYANDWEEYVTRQARWVNFKNSYKTMDKNFMESVLWAFKELYNKGLLYES
HHHHHHHHHHHHHHHHHHHHHHHHHEEECCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHH
MRVMPYSWACETPLSNFETRLDNSYRERADKAVTVSFVLSHPVATTTGSFKEYRILAWTT
HHCCCCCCCCCCCHHHHHHHHCHHHHHHCCCEEEEEEEECCCCCCCCCCCCEEEEEEEEC
TPWTLPSNLALAVGSDIDYALVPKNDVCYIIAAYSVSKYAKELGLSGEENFEIIKGSALQ
CCCCCCCCCEEEECCCCCEEEECCCCEEEEEEEHHHHHHHHHHCCCCCCCCEEEECCCCC
GLNYKSLFDYFENHPNSFKIFAGDFVVEGDGTGVVHMAPGFGEDDQILCESKGIELVCPV
CCCHHHHHHHHHCCCCCEEEEECCEEEECCCCEEEEECCCCCCCCCEEEECCCCEEEEEC
DNSGKFTKEIPDLEGLQVFDANDKIIIKLKEQGNWLKTEQYIHNYPHCWRTDTPLIYKAV
CCCCCCHHCCCCCCCEEEEECCCEEEEEECCCCCEEHHHHHHHCCCCCCCCCCCEEEEEC
PSWYVKVTQFKDRMVELNQQINWIPFHVKDNLFGKWLENARDWSISRNRFWGTPLPVWKS
CCCEEEHHHHHHHHHHHHCCCCEEEEEECCCHHHHHHCCCCCCCCCCCCCCCCCCCCCCC
DDPKYPRIDVYGSIEELEKDFGVKVTDLHRPFIDELTRPNPDDPTGKSTMRRIEDVFDCW
CCCCCCEEEECCCHHHHHHHHCCEEEECCCHHHHHHCCCCCCCCCCHHHHHHHHHHHHHH
FESGSMPYGQAHYPFENKEWFEDHFPADFIVEYSAQTRGWFYTLMVLSTALFDRPPFLNC
HHCCCCCCCCCCCCCCCCCHHHHCCCCCEEEEECCCCCCHHHHHHHHHHHHHCCCCHHHH
ICHGIILDSTGQKLSKRLNNYADPLELFDKYGSDALRVTMLSSNVVKGQELLIDKDGKMV
HHHHHEECCCCHHHHHHHHCCCCHHHHHHHCCCCEEEEEEECCCCCCCCEEEEECCCCHH
FDTLRLFIKPIWNAYHFFTMYANTDSLKGKLNFSSKNVLDVYILSKLKIAVQKIEESLDN
HHHHHHHHHHHHHHEEEEEEEECCCCCCEEEECCCCCEEEHHHHHHHHHHHHHHHHHHHC
FDTQTAYHAVSEFFEVLNNWYIRRSRARFWKSEKDTDKQNAYNTLYSCLDTMAIAMSALV
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
PMISEAIYKGLHHCEERNDTALSGKSNVIVRKDTSLDKAISGVSHKIATALSVPCNDAIS
HHHHHHHHHHHHHHHCCCCCEECCCCCEEEEECCCHHHHHHHHHHHHHHHEECCCCCCEE
VHLCNYPTLSDFEINHELVATMDNVLDICSNSLFIRSTENIRVRQPLASIAIISKHNNNL
EEEECCCCCCCCCCCHHHHHHHHHHHHHHCCCEEEEECCCEEEECCHHHEEEEECCCCCH
KDFEDLIKDEINVKAVIYRDDLENYASKKLSINFPMLGKRLPHKMKEIIAASKKGEWEAI
HHHHHHHHCCCCEEEEEEECHHHHHHCCEEEECCCHHHHCCHHHHHHHHHHCCCCCHHHH
AGGLAICGETLNSDEYKLVLEPYSHIKGAASFENNSSLLILDLELTPELIEEGYARDIVR
HCCHHHHCCCCCCCCEEEEECCHHHCCCCCCCCCCCCEEEEEECCCHHHHHCCHHHHHHH
FIQQARKDADFSITDRILIEIISEFNLSKIIDNYGDFIKEQTLGEFAKNFTPDYVSKVEL
HHHHHHCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHEEE
ENHQIQLKVKKS
CCCEEEEEEECC
>Mature Secondary Structure 
TNTKYYPEVNSNADFAGLEREILKFWQDNNIFQKSIDDRNGELEFIFYDGPPFANGLPH
CCCCCCCCCCCCCCHHHHHHHHHHHHCCCCHHHHHCCCCCCCEEEEEECCCCCCCCCCH
YGHLLTGFIKDVYARYQTIKGKKVERRFGWDCHGLPAEMQSEKELGISGRLAIANFGIEK
HHHHHHHHHHHHHHHHHHCCCCHHHHHCCCCCCCCCHHHCCCCCCCCCCEEEEEECCHHH
FNAHCRASVMKYANDWEEYVTRQARWVNFKNSYKTMDKNFMESVLWAFKELYNKGLLYES
HHHHHHHHHHHHHHHHHHHHHHHHHEEECCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHH
MRVMPYSWACETPLSNFETRLDNSYRERADKAVTVSFVLSHPVATTTGSFKEYRILAWTT
HHCCCCCCCCCCCHHHHHHHHCHHHHHHCCCEEEEEEEECCCCCCCCCCCCEEEEEEEEC
TPWTLPSNLALAVGSDIDYALVPKNDVCYIIAAYSVSKYAKELGLSGEENFEIIKGSALQ
CCCCCCCCCEEEECCCCCEEEECCCCEEEEEEEHHHHHHHHHHCCCCCCCCEEEECCCCC
GLNYKSLFDYFENHPNSFKIFAGDFVVEGDGTGVVHMAPGFGEDDQILCESKGIELVCPV
CCCHHHHHHHHHCCCCCEEEEECCEEEECCCCEEEEECCCCCCCCCEEEECCCCEEEEEC
DNSGKFTKEIPDLEGLQVFDANDKIIIKLKEQGNWLKTEQYIHNYPHCWRTDTPLIYKAV
CCCCCCHHCCCCCCCEEEEECCCEEEEEECCCCCEEHHHHHHHCCCCCCCCCCCEEEEEC
PSWYVKVTQFKDRMVELNQQINWIPFHVKDNLFGKWLENARDWSISRNRFWGTPLPVWKS
CCCEEEHHHHHHHHHHHHCCCCEEEEEECCCHHHHHHCCCCCCCCCCCCCCCCCCCCCCC
DDPKYPRIDVYGSIEELEKDFGVKVTDLHRPFIDELTRPNPDDPTGKSTMRRIEDVFDCW
CCCCCCEEEECCCHHHHHHHHCCEEEECCCHHHHHHCCCCCCCCCCHHHHHHHHHHHHHH
FESGSMPYGQAHYPFENKEWFEDHFPADFIVEYSAQTRGWFYTLMVLSTALFDRPPFLNC
HHCCCCCCCCCCCCCCCCCHHHHCCCCCEEEEECCCCCCHHHHHHHHHHHHHCCCCHHHH
ICHGIILDSTGQKLSKRLNNYADPLELFDKYGSDALRVTMLSSNVVKGQELLIDKDGKMV
HHHHHEECCCCHHHHHHHHCCCCHHHHHHHCCCCEEEEEEECCCCCCCCEEEEECCCCHH
FDTLRLFIKPIWNAYHFFTMYANTDSLKGKLNFSSKNVLDVYILSKLKIAVQKIEESLDN
HHHHHHHHHHHHHHEEEEEEEECCCCCCEEEECCCCCEEEHHHHHHHHHHHHHHHHHHHC
FDTQTAYHAVSEFFEVLNNWYIRRSRARFWKSEKDTDKQNAYNTLYSCLDTMAIAMSALV
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
PMISEAIYKGLHHCEERNDTALSGKSNVIVRKDTSLDKAISGVSHKIATALSVPCNDAIS
HHHHHHHHHHHHHHHCCCCCEECCCCCEEEEECCCHHHHHHHHHHHHHHHEECCCCCCEE
VHLCNYPTLSDFEINHELVATMDNVLDICSNSLFIRSTENIRVRQPLASIAIISKHNNNL
EEEECCCCCCCCCCCHHHHHHHHHHHHHHCCCEEEEECCCEEEECCHHHEEEEECCCCCH
KDFEDLIKDEINVKAVIYRDDLENYASKKLSINFPMLGKRLPHKMKEIIAASKKGEWEAI
HHHHHHHHCCCCEEEEEEECHHHHHHCCEEEECCCHHHHCCHHHHHHHHHHCCCCCHHHH
AGGLAICGETLNSDEYKLVLEPYSHIKGAASFENNSSLLILDLELTPELIEEGYARDIVR
HCCHHHHCCCCCCCCEEEEECCHHHCCCCCCCCCCCCEEEEEECCCHHHHHCCHHHHHHH
FIQQARKDADFSITDRILIEIISEFNLSKIIDNYGDFIKEQTLGEFAKNFTPDYVSKVEL
HHHHHHCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHEEE
ENHQIQLKVKKS
CCCEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA