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The map label for this gene is cysQ [H]

Identifier: 229586553

GI number: 229586553

Start: 400203

End: 400979

Strand: Direct

Name: cysQ [H]

Synonym: RAF_ORF0374

Alternate gene names: 229586553

Gene position: 400203-400979 (Clockwise)

Preceding gene: 229586552

Following gene: 229586556

Centisome position: 31.3

GC content: 33.72

Gene sequence:

>777_bases
ATGAATGACAATTTAATTAATGCTTTAAAAGATTTAATTATTAATACCGGCAAGATTGCACTAGATATAAAAAAGGCAGG
AATGTTGATTGATATTAAATCAGATGGGTCAGTAGTCACTAATGCCGATAAAGAAATTAGTAAAATAATTTATCAAACTC
TACAAACCTTAACCTCTCAAATAGCTATAGTATGTGAAGAGCAGCCGCTACCTATATTCAGCAGTGATACTTTTTGGTTA
ATCGATCCTATTGATGGGACATGGAGCTATGTAAACGGTAAAAGTACATATACGGTCAATATAGGGCTTATTGAAAACGG
TTTGCCAACCATCGGCTTGATATATCACCCTGAAACAGCAAAGCTATATTATACTGATGTAAACGGTCGGTTAAAAATCG
AACAGAATTCTAAAGAAATATTTGTTAATCATGAACTGAAACATGAAGAGCTTAATGCGGTAATAGGTTTTTATAATTCA
AATAAAGCTACTAAAGAATTTTTAAGTAAGTATTCATTCGGTCAAATAAATGCAATAGGCAGTTCAATGAAACTATGCTT
AATTGCTGAAGGAGCAGCTGATATATATCCAAAATTCGGTCAAACTATGGAATGGGACATAGCGGCAGGTCATGCTTTAA
TTAAAGCCGGTGGTGGTAATATTTTAGATACGCATGGACAAGAAATTACTTACGGTAAAGAAAGTTTTGCTAATCCTAAT
TTTTTCGCCTGTAGTAAATATTGGTTGGAACGGGAGGCAAGGTTGCATAGATACTAG

Upstream 100 bases:

>100_bases
CACCTGATCATCAAATCGCTGAGTTGCAGCAATCTACGTTTTTAAATACCGGTCAGTGGTTAGAAGATGATACAGCTGCA
AAGATGTTAAATAAATAATT

Downstream 100 bases:

>100_bases
ATCGTCATTGCAAGCAGCAGTAGGCTGCGTGGCAATCTCATGAAATAATCACAAACTCCTGAGATTGCTTTATCAAAACT
TGCAGTTTTTCCTCGCAATG

Product: 3(2),5-bisphosphate nucleotidase

Products: NA

Alternate protein names: 3'(2'),5-bisphosphonucleoside 3'(2')-phosphohydrolase; 3'-phosphoadenosine 5'-phosphate phosphatase; PAP phosphatase; DPNPase [H]

Number of amino acids: Translated: 258; Mature: 258

Protein sequence:

>258_residues
MNDNLINALKDLIINTGKIALDIKKAGMLIDIKSDGSVVTNADKEISKIIYQTLQTLTSQIAIVCEEQPLPIFSSDTFWL
IDPIDGTWSYVNGKSTYTVNIGLIENGLPTIGLIYHPETAKLYYTDVNGRLKIEQNSKEIFVNHELKHEELNAVIGFYNS
NKATKEFLSKYSFGQINAIGSSMKLCLIAEGAADIYPKFGQTMEWDIAAGHALIKAGGGNILDTHGQEITYGKESFANPN
FFACSKYWLEREARLHRY

Sequences:

>Translated_258_residues
MNDNLINALKDLIINTGKIALDIKKAGMLIDIKSDGSVVTNADKEISKIIYQTLQTLTSQIAIVCEEQPLPIFSSDTFWL
IDPIDGTWSYVNGKSTYTVNIGLIENGLPTIGLIYHPETAKLYYTDVNGRLKIEQNSKEIFVNHELKHEELNAVIGFYNS
NKATKEFLSKYSFGQINAIGSSMKLCLIAEGAADIYPKFGQTMEWDIAAGHALIKAGGGNILDTHGQEITYGKESFANPN
FFACSKYWLEREARLHRY
>Mature_258_residues
MNDNLINALKDLIINTGKIALDIKKAGMLIDIKSDGSVVTNADKEISKIIYQTLQTLTSQIAIVCEEQPLPIFSSDTFWL
IDPIDGTWSYVNGKSTYTVNIGLIENGLPTIGLIYHPETAKLYYTDVNGRLKIEQNSKEIFVNHELKHEELNAVIGFYNS
NKATKEFLSKYSFGQINAIGSSMKLCLIAEGAADIYPKFGQTMEWDIAAGHALIKAGGGNILDTHGQEITYGKESFANPN
FFACSKYWLEREARLHRY

Specific function: Converts 3'(2')-phosphoadenosine 5'-phosphate (PAP) to AMP. May also convert adenosine 3'-phosphate 5'-phosphosulfate (PAPS) to adenosine 5'-phosphosulfate (APS) [H]

COG id: COG1218

COG function: function code P; 3'-Phosphoadenosine 5'-phosphosulfate (PAPS) 3'-phosphatase

Gene ontology:

Cell location: Cytoplasm. Cell membrane; Peripheral membrane protein; Cytoplasmic side [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the inositol monophosphatase family [H]

Homologues:

Organism=Homo sapiens, GI7657236, Length=207, Percent_Identity=30.4347826086957, Blast_Score=79, Evalue=4e-15,
Organism=Escherichia coli, GI1790659, Length=247, Percent_Identity=33.6032388663968, Blast_Score=122, Evalue=3e-29,
Organism=Saccharomyces cerevisiae, GI6320493, Length=208, Percent_Identity=27.4038461538462, Blast_Score=67, Evalue=3e-12,
Organism=Saccharomyces cerevisiae, GI6321836, Length=230, Percent_Identity=24.7826086956522, Blast_Score=66, Evalue=6e-12,
Organism=Drosophila melanogaster, GI21357303, Length=168, Percent_Identity=28.5714285714286, Blast_Score=69, Evalue=2e-12,
Organism=Drosophila melanogaster, GI21357329, Length=210, Percent_Identity=24.7619047619048, Blast_Score=68, Evalue=5e-12,
Organism=Drosophila melanogaster, GI24664926, Length=202, Percent_Identity=27.2277227722772, Blast_Score=68, Evalue=5e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006240
- InterPro:   IPR020583
- InterPro:   IPR000760
- InterPro:   IPR020550 [H]

Pfam domain/function: PF00459 Inositol_P [H]

EC number: =3.1.3.7 [H]

Molecular weight: Translated: 28781; Mature: 28781

Theoretical pI: Translated: 5.63; Mature: 5.63

Prosite motif: PS00629 IMP_1 ; PS00630 IMP_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNDNLINALKDLIINTGKIALDIKKAGMLIDIKSDGSVVTNADKEISKIIYQTLQTLTSQ
CCCHHHHHHHHHHCCCCEEEEEEECCCEEEEECCCCCEEECCHHHHHHHHHHHHHHHHHH
IAIVCEEQPLPIFSSDTFWLIDPIDGTWSYVNGKSTYTVNIGLIENGLPTIGLIYHPETA
EEEEECCCCCCEECCCCEEEEECCCCCEEEECCCEEEEEEEEEEECCCCEEEEEECCCCC
KLYYTDVNGRLKIEQNSKEIFVNHELKHEELNAVIGFYNSNKATKEFLSKYSFGQINAIG
EEEEEECCCEEEEECCCCEEEEECCCCHHHHEEEEEEECCCHHHHHHHHHCCCCEEEECC
SSMKLCLIAEGAADIYPKFGQTMEWDIAAGHALIKAGGGNILDTHGQEITYGKESFANPN
CCEEEEEEECCCHHHCCCCCCCEEEEEECCEEEEEECCCCEEECCCCEEEECHHHCCCCC
FFACSKYWLEREARLHRY
EEEHHHHHHHHHHHHCCC
>Mature Secondary Structure
MNDNLINALKDLIINTGKIALDIKKAGMLIDIKSDGSVVTNADKEISKIIYQTLQTLTSQ
CCCHHHHHHHHHHCCCCEEEEEEECCCEEEEECCCCCEEECCHHHHHHHHHHHHHHHHHH
IAIVCEEQPLPIFSSDTFWLIDPIDGTWSYVNGKSTYTVNIGLIENGLPTIGLIYHPETA
EEEEECCCCCCEECCCCEEEEECCCCCEEEECCCEEEEEEEEEEECCCCEEEEEECCCCC
KLYYTDVNGRLKIEQNSKEIFVNHELKHEELNAVIGFYNSNKATKEFLSKYSFGQINAIG
EEEEEECCCEEEEECCCCEEEEECCCCHHHHEEEEEEECCCHHHHHHHHHCCCCEEEECC
SSMKLCLIAEGAADIYPKFGQTMEWDIAAGHALIKAGGGNILDTHGQEITYGKESFANPN
CCEEEEEEECCCHHHCCCCCCCEEEEEECCEEEEEECCCCEEECCCCEEEECHHHCCCCC
FFACSKYWLEREARLHRY
EEEHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 10993077 [H]