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The map label for this gene is coxW

Identifier: 229586507

GI number: 229586507

Start: 347454

End: 348467

Strand: Direct

Name: coxW

Synonym: RAF_ORF0319

Alternate gene names: 229586507

Gene position: 347454-348467 (Clockwise)

Preceding gene: 229586506

Following gene: 229586508

Centisome position: 27.18

GC content: 30.28

Gene sequence:

>1014_bases
GTGCAGAAAAGTTTAATTACAAAATGGTTGTGTATAAGTTGTATAATGGTCATAGCGACGATTGTTATAGGGGGGATAAC
AAGGCTTACCGGTTCTGGTTTATCTATAGTTGAGTGGCGTCCGGTAACCGGTATTTTGCCGCCTTTTAGTTTTGAAAGCT
GGCAATCGGAATTTGCTAAATATAAAGCTTTTCCTGAATATAACTCCGTTAATTACGGAATTACTTTATCACAGTTTAAG
TTTATTTATCTGTTAGAGTTTATACATCGATTACTCGGTAGAATTACAGCTTTAATATATATTGTACCTTTAATATATTT
TTATTTTAAAGATGTTATAAAAAATCGTGACATGCTACCTTATATAATTGCTTTGTTGTTATTTTGCATACAAGGCTTTA
TAGGGTGGTATATGGTTAAAAGCGGCTTGTTGAATAGCCCGTATGTTAGTCATTTTCGACTTGCTTTTCATTTAATTATC
GCCGTAATTATTTATCACATACTTTTTTATCAACTAATAAAAAATCGTTGTGATATTTTGTTAATCCTGTCACAAACAGA
TTTTAAATTACCATTAATATTTTCCGGTATTGCTATTACTGTAGTATATGTGCAAATTTTTTTAGGTGCTTTAGTTGCAG
GGCTTGATGCAGGGCTGATATATAATAGTTTTCCGCTAATGGATGATAGATTTATCCCGATGGAGATAAAAGATAATTTC
TTTGATCTTAAAAATTGGTATGATCCGGTTTTTATACAATTCATACATCGTTTAGTTGGCTATAGCGTATTTTTGGTTGT
TGTAGTTTTGATAATTTGCTTGTTAAAAATAGAGCATCCGAAATTAAATAAGATAGCGTATTTTCTAATGATTGTATTAT
TTATGCAGGTATCTACCGGAATAATTACTCTTTTATACTCTGTACCTATAATAATTGCCTCTATACATCAGCTTTTTGCT
ATAATCCTTTTATCTATAATAATTTGGTGCTATTTTTTAATAAAAAGTTCCTAA

Upstream 100 bases:

>100_bases
GGGATGATAAATGATAAACCTATCCACGCCACAAGGCCTACGCGGGGATGACATAGCAATGCTGTAATGACGCGATACAA
AACATAAACTTAAAATAAAA

Downstream 100 bases:

>100_bases
TTTATTAAAAATATGATCATCGATGTCAATACTCCTATTTCTTCTAGATTAGATAAATATTTAAAACGTCTATATCCCTT
ATTGACTCAAGGAGTAATAG

Product: Cytochrome c oxidase assembly protein

Products: NA

Alternate protein names: HAS; Cytochrome aa3-controlling protein

Number of amino acids: Translated: 337; Mature: 337

Protein sequence:

>337_residues
MQKSLITKWLCISCIMVIATIVIGGITRLTGSGLSIVEWRPVTGILPPFSFESWQSEFAKYKAFPEYNSVNYGITLSQFK
FIYLLEFIHRLLGRITALIYIVPLIYFYFKDVIKNRDMLPYIIALLLFCIQGFIGWYMVKSGLLNSPYVSHFRLAFHLII
AVIIYHILFYQLIKNRCDILLILSQTDFKLPLIFSGIAITVVYVQIFLGALVAGLDAGLIYNSFPLMDDRFIPMEIKDNF
FDLKNWYDPVFIQFIHRLVGYSVFLVVVVLIICLLKIEHPKLNKIAYFLMIVLFMQVSTGIITLLYSVPIIIASIHQLFA
IILLSIIIWCYFLIKSS

Sequences:

>Translated_337_residues
MQKSLITKWLCISCIMVIATIVIGGITRLTGSGLSIVEWRPVTGILPPFSFESWQSEFAKYKAFPEYNSVNYGITLSQFK
FIYLLEFIHRLLGRITALIYIVPLIYFYFKDVIKNRDMLPYIIALLLFCIQGFIGWYMVKSGLLNSPYVSHFRLAFHLII
AVIIYHILFYQLIKNRCDILLILSQTDFKLPLIFSGIAITVVYVQIFLGALVAGLDAGLIYNSFPLMDDRFIPMEIKDNF
FDLKNWYDPVFIQFIHRLVGYSVFLVVVVLIICLLKIEHPKLNKIAYFLMIVLFMQVSTGIITLLYSVPIIIASIHQLFA
IILLSIIIWCYFLIKSS
>Mature_337_residues
MQKSLITKWLCISCIMVIATIVIGGITRLTGSGLSIVEWRPVTGILPPFSFESWQSEFAKYKAFPEYNSVNYGITLSQFK
FIYLLEFIHRLLGRITALIYIVPLIYFYFKDVIKNRDMLPYIIALLLFCIQGFIGWYMVKSGLLNSPYVSHFRLAFHLII
AVIIYHILFYQLIKNRCDILLILSQTDFKLPLIFSGIAITVVYVQIFLGALVAGLDAGLIYNSFPLMDDRFIPMEIKDNF
FDLKNWYDPVFIQFIHRLVGYSVFLVVVVLIICLLKIEHPKLNKIAYFLMIVLFMQVSTGIITLLYSVPIIIASIHQLFA
IILLSIIIWCYFLIKSS

Specific function: Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group

COG id: COG1612

COG function: function code O; Uncharacterized protein required for cytochrome oxidase assembly

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the COX15/CtaA family. Type 2 subfamily

Homologues:

Organism=Homo sapiens, GI17921985, Length=344, Percent_Identity=36.9186046511628, Blast_Score=222, Evalue=3e-58,
Organism=Homo sapiens, GI17921987, Length=307, Percent_Identity=36.4820846905537, Blast_Score=199, Evalue=4e-51,
Organism=Caenorhabditis elegans, GI17536069, Length=347, Percent_Identity=34.2939481268012, Blast_Score=204, Evalue=4e-53,
Organism=Saccharomyces cerevisiae, GI6320989, Length=352, Percent_Identity=36.0795454545455, Blast_Score=202, Evalue=8e-53,
Organism=Drosophila melanogaster, GI19922860, Length=346, Percent_Identity=32.6589595375723, Blast_Score=199, Evalue=2e-51,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): CTAA_RICAE (C3PMV5)

Other databases:

- EMBL:   CP001612
- RefSeq:   YP_002845008.1
- GeneID:   7815319
- GenomeReviews:   CP001612_GR
- KEGG:   raf:RAF_ORF0319
- OMA:   GLSIVEW
- ProtClustDB:   CLSK864993
- HAMAP:   MF_01665
- InterPro:   IPR003780

Pfam domain/function: PF02628 COX15-CtaA

EC number: NA

Molecular weight: Translated: 38925; Mature: 38925

Theoretical pI: Translated: 9.16; Mature: 9.16

Prosite motif: NA

Important sites: BINDING 316-316

Signals:

None

Transmembrane regions:

HASH(0x21183770)-; HASH(0x1fd2ea34)-; HASH(0x20fc2e50)-; HASH(0x20da61a0)-; HASH(0x20cc3bac)-; HASH(0x20f4ec6c)-; HASH(0x20271e34)-; HASH(0x1fb72988)-;

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQKSLITKWLCISCIMVIATIVIGGITRLTGSGLSIVEWRPVTGILPPFSFESWQSEFAK
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCHHHHHHHHHH
YKAFPEYNSVNYGITLSQFKFIYLLEFIHRLLGRITALIYIVPLIYFYFKDVIKNRDMLP
HCCCCCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHH
YIIALLLFCIQGFIGWYMVKSGLLNSPYVSHFRLAFHLIIAVIIYHILFYQLIKNRCDIL
HHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEE
LILSQTDFKLPLIFSGIAITVVYVQIFLGALVAGLDAGLIYNSFPLMDDRFIPMEIKDNF
EEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHCCCH
FDLKNWYDPVFIQFIHRLVGYSVFLVVVVLIICLLKIEHPKLNKIAYFLMIVLFMQVSTG
HHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHH
IITLLYSVPIIIASIHQLFAIILLSIIIWCYFLIKSS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCH
>Mature Secondary Structure
MQKSLITKWLCISCIMVIATIVIGGITRLTGSGLSIVEWRPVTGILPPFSFESWQSEFAK
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCHHHHHHHHHH
YKAFPEYNSVNYGITLSQFKFIYLLEFIHRLLGRITALIYIVPLIYFYFKDVIKNRDMLP
HCCCCCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHH
YIIALLLFCIQGFIGWYMVKSGLLNSPYVSHFRLAFHLIIAVIIYHILFYQLIKNRCDIL
HHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEE
LILSQTDFKLPLIFSGIAITVVYVQIFLGALVAGLDAGLIYNSFPLMDDRFIPMEIKDNF
EEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHCCCH
FDLKNWYDPVFIQFIHRLVGYSVFLVVVVLIICLLKIEHPKLNKIAYFLMIVLFMQVSTG
HHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHH
IITLLYSVPIIIASIHQLFAIILLSIIIWCYFLIKSS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA