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The map label for this gene is ribB [H]

Identifier: 229264289

GI number: 229264289

Start: 1732565

End: 1733701

Strand: Reverse

Name: ribB [H]

Synonym: BTH_I1531

Alternate gene names: 229264289

Gene position: 1733701-1732565 (Counterclockwise)

Preceding gene: 83719775

Following gene: 161723127

Centisome position: 45.51

GC content: 67.72

Gene sequence:

>1137_bases
ATGACGCTCGCCTCCACGCCCGACATCATTGCCGAGCTCAAAGCCGGCCGGATGGTGATCCTGGTCGACGAAGAAGACCG
CGAAAACGAGGGCGACCTCGTGCTTGCCGCCGAGTTCGTCACGCCGGAAGCGATCAACTTCATGGCCCGCTACGGCCGCG
GCCTGATCTGCCTCACGCTCACGCAGGAGCGCTGCAAGCAGCTCAACCTGCCGCTGATGACGTATCGCAACGGCACCCAG
TACGGCACCGCGTTCACGGTCAGCATCGAAGCGGCCGAAGGCGTGACGACGGGCATCTCGGCCGCGGACCGCGCGCGCAC
GATCGCGACCGCGGTCGCGCACGACGTGCGCCCGGAGCACATCGTGCAGCCGGGCCACGTGTTCCCGATCATGGCGCAGC
CGGGCGGCGTGCTGGTGCGCGCGGGCCACACCGAGGCGGGCTGCGATCTCACGGCGCTCGCGGGTCTCACGCCCGCCGCC
GTGATCTGCGAGATCATCAAGGACGACGGCACGATGGCGCGCCTGCCGGACCTGATCGAATTCGGCAAGGAACACGGCCT
GAAGATCGGCACGATCGCCGATCTGATCCACTACCGCAGCCGGACCGAATCGATCGTCGAGCGCGTCGCCGAACGCACGA
TGCAGACCGCGCACGGCCCGTTCAAGGCAGTGCTGTATCGCGATCACCCGACGGGCTCGCCGCACATCGCGCTCGTGCGC
GGCACGCCCGCGCCGCACGACGAGACGCCCGTGCGCGTGCACGAGCCGCTGTCCGTGCTCGACCTGCTCGAAACCGGCGT
GTCGACCCATTCGTGGACGCTCGACGCCGCAATGAAGGAAATCGCCGCGCGCGAGCTCGGCGTGGTCGTGCTCCTGAACT
GCGGCGACACGAAAGAGCACCTCGTCGACGTGTTCCTCGCGTTCGACGAAAAGGAAAAGGCGGCCGAGCTCAAACGCCGG
CCGGTCGATTTCAAGACGTTCGGCATCGGCGCGCAAATCCTGCGCGACGTCGGTGTCGGCAAGATGCAGGTGCTGTCGAA
TCCGCGCAAGCTCGGCAGCATGTCGGGCTACGGCCTCGAAGTCACCGGCTTCGCGCCGATGCCGGGGAGCGCAACGTCCG
CGTCCGACGCCGCATAA

Upstream 100 bases:

>100_bases
TCGGCCGTCCGGCCAACGCGGCCGCCCGTCGCGTCGCGTCCGGCTAAAACCCGCCGCGCGTGGCGTAAAATACGCGCTTT
CCCTTCCCCCTGATCCTTTT

Downstream 100 bases:

>100_bases
CGGGTTTCGCGTCATCGCCGTACCGTTGTCAGCCTGTGCTGCAGCCCCTATCACCGCTCATCCACTCTACGGAAAGAACA
TGGAAATCGGACAATATCAA

Product: bifunctional 3,4-dihydroxy-2-butanone 4-phosphate synthase/GTP cyclohydrolase II-like protein

Products: NA

Alternate protein names: DHBP synthase [H]

Number of amino acids: Translated: 378; Mature: 377

Protein sequence:

>378_residues
MTLASTPDIIAELKAGRMVILVDEEDRENEGDLVLAAEFVTPEAINFMARYGRGLICLTLTQERCKQLNLPLMTYRNGTQ
YGTAFTVSIEAAEGVTTGISAADRARTIATAVAHDVRPEHIVQPGHVFPIMAQPGGVLVRAGHTEAGCDLTALAGLTPAA
VICEIIKDDGTMARLPDLIEFGKEHGLKIGTIADLIHYRSRTESIVERVAERTMQTAHGPFKAVLYRDHPTGSPHIALVR
GTPAPHDETPVRVHEPLSVLDLLETGVSTHSWTLDAAMKEIAARELGVVVLLNCGDTKEHLVDVFLAFDEKEKAAELKRR
PVDFKTFGIGAQILRDVGVGKMQVLSNPRKLGSMSGYGLEVTGFAPMPGSATSASDAA

Sequences:

>Translated_378_residues
MTLASTPDIIAELKAGRMVILVDEEDRENEGDLVLAAEFVTPEAINFMARYGRGLICLTLTQERCKQLNLPLMTYRNGTQ
YGTAFTVSIEAAEGVTTGISAADRARTIATAVAHDVRPEHIVQPGHVFPIMAQPGGVLVRAGHTEAGCDLTALAGLTPAA
VICEIIKDDGTMARLPDLIEFGKEHGLKIGTIADLIHYRSRTESIVERVAERTMQTAHGPFKAVLYRDHPTGSPHIALVR
GTPAPHDETPVRVHEPLSVLDLLETGVSTHSWTLDAAMKEIAARELGVVVLLNCGDTKEHLVDVFLAFDEKEKAAELKRR
PVDFKTFGIGAQILRDVGVGKMQVLSNPRKLGSMSGYGLEVTGFAPMPGSATSASDAA
>Mature_377_residues
TLASTPDIIAELKAGRMVILVDEEDRENEGDLVLAAEFVTPEAINFMARYGRGLICLTLTQERCKQLNLPLMTYRNGTQY
GTAFTVSIEAAEGVTTGISAADRARTIATAVAHDVRPEHIVQPGHVFPIMAQPGGVLVRAGHTEAGCDLTALAGLTPAAV
ICEIIKDDGTMARLPDLIEFGKEHGLKIGTIADLIHYRSRTESIVERVAERTMQTAHGPFKAVLYRDHPTGSPHIALVRG
TPAPHDETPVRVHEPLSVLDLLETGVSTHSWTLDAAMKEIAARELGVVVLLNCGDTKEHLVDVFLAFDEKEKAAELKRRP
VDFKTFGIGAQILRDVGVGKMQVLSNPRKLGSMSGYGLEVTGFAPMPGSATSASDAA

Specific function: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate [H]

COG id: COG0108

COG function: function code H; 3,4-dihydroxy-2-butanone 4-phosphate synthase

Gene ontology:

Cell location: Membrane-Associated [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the GTP cyclohydrolase II family [H]

Homologues:

Organism=Escherichia coli, GI1789420, Length=196, Percent_Identity=53.0612244897959, Blast_Score=222, Evalue=3e-59,
Organism=Saccharomyces cerevisiae, GI6320695, Length=202, Percent_Identity=42.5742574257426, Blast_Score=165, Evalue=1e-41,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017945
- InterPro:   IPR000422
- InterPro:   IPR000926
- InterPro:   IPR016299 [H]

Pfam domain/function: PF00926 DHBP_synthase; PF00925 GTP_cyclohydro2 [H]

EC number: =4.1.99.12 [H]

Molecular weight: Translated: 40631; Mature: 40500

Theoretical pI: Translated: 5.74; Mature: 5.74

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLASTPDIIAELKAGRMVILVDEEDRENEGDLVLAAEFVTPEAINFMARYGRGLICLTL
CCCCCCCHHHHHHCCCCEEEEECCCCCCCCCCEEEEEECCCHHHHHHHHHHCCCEEEEEE
TQERCKQLNLPLMTYRNGTQYGTAFTVSIEAAEGVTTGISAADRARTIATAVAHDVRPEH
CHHHHHHCCCCEEEECCCCCCCEEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHCCCHHH
IVQPGHVFPIMAQPGGVLVRAGHTEAGCDLTALAGLTPAAVICEIIKDDGTMARLPDLIE
CCCCCCEEEEEECCCCEEEECCCCCCCCCHHHHHCCCHHHHHHHHHHCCCCHHHHHHHHH
FGKEHGLKIGTIADLIHYRSRTESIVERVAERTMQTAHGPFKAVLYRDHPTGSPHIALVR
HHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCEEEEE
GTPAPHDETPVRVHEPLSVLDLLETGVSTHSWTLDAAMKEIAARELGVVVLLNCGDTKEH
CCCCCCCCCCEEECCCHHHHHHHHCCCCCCCEEHHHHHHHHHHHHCCEEEEEECCCCHHH
LVDVFLAFDEKEKAAELKRRPVDFKTFGIGAQILRDVGVGKMQVLSNPRKLGSMSGYGLE
HHHHHHHCCCHHHHHHHHHCCCCEEEECCHHHHHHHCCCCHHHHHCCCHHHCCCCCCCEE
VTGFAPMPGSATSASDAA
EEECCCCCCCCCCCCCCC
>Mature Secondary Structure 
TLASTPDIIAELKAGRMVILVDEEDRENEGDLVLAAEFVTPEAINFMARYGRGLICLTL
CCCCCCHHHHHHCCCCEEEEECCCCCCCCCCEEEEEECCCHHHHHHHHHHCCCEEEEEE
TQERCKQLNLPLMTYRNGTQYGTAFTVSIEAAEGVTTGISAADRARTIATAVAHDVRPEH
CHHHHHHCCCCEEEECCCCCCCEEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHCCCHHH
IVQPGHVFPIMAQPGGVLVRAGHTEAGCDLTALAGLTPAAVICEIIKDDGTMARLPDLIE
CCCCCCEEEEEECCCCEEEECCCCCCCCCHHHHHCCCHHHHHHHHHHCCCCHHHHHHHHH
FGKEHGLKIGTIADLIHYRSRTESIVERVAERTMQTAHGPFKAVLYRDHPTGSPHIALVR
HHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCEEEEE
GTPAPHDETPVRVHEPLSVLDLLETGVSTHSWTLDAAMKEIAARELGVVVLLNCGDTKEH
CCCCCCCCCCEEECCCHHHHHHHHCCCCCCCEEHHHHHHHHHHHHCCEEEEEECCCCHHH
LVDVFLAFDEKEKAAELKRRPVDFKTFGIGAQILRDVGVGKMQVLSNPRKLGSMSGYGLE
HHHHHHHCCCHHHHHHHHHCCCCEEEECCHHHHHHHCCCCHHHHHCCCHHHCCCCCCCEE
VTGFAPMPGSATSASDAA
EEECCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10761919 [H]