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The map label for this gene is cirA [H]

Identifier: 229220584

GI number: 229220584

Start: 2820975

End: 2822963

Strand: Direct

Name: cirA [H]

Synonym: Sbal_2423

Alternate gene names: 229220584

Gene position: 2820975-2822963 (Clockwise)

Preceding gene: 126174635

Following gene: 126174638

Centisome position: 55.02

GC content: 50.53

Gene sequence:

>1989_bases
ATGTCCCGCTTAATCCGCCGTACTCGCAAAACAAGTCATACATCCGGTGCAGCTCTGTCTCCTAAACTGAGCCTGCTATC
GCGCGCCATTGGCTTAAGCCTGTTGTTACCCGCTGCATGGGCAACTGCCGCAGCTCCCCAAGATGCCACGCCAGAAATGG
AACGTATGGTGATCACAGCTACGCAAACTCAGCATTCGGAACTGTCGGCGCCCGCTTCTGTGTCAGTAATTAATCGCAGT
GAACTCGAAGCGCTAGTGATCGACGATCTGGCCAGTGCAGTGCGTTATTTACAGGGCGTGAATATCAGTGAAGGCACGCC
CTATGGTCGCAATGAAATTAGCCTACGCGGACTGGATTCGGACTACACGCTGATCTTAATCAACGGTCGGCGAGTCAACT
CCCGCGAAGCGCTAACCTCCGGTTATGGCAACGATTTTGACTTATCATCCATTCCTATGTCTGCGATTGAGCGTATCGAA
GTCGTGCGCGGGCCCATGTCATCCCTGTATGGCTCCGAAGCTTTAGGCGGTGTGGTTAACGTGATTTTGCGCCAACCCAC
TGACGACTGGCAGACCAGTGTAGGCGTGCAATACGATACGCCCACCAGCGGCAAAGGCGGCGACAGCACTAAGTACAATT
TCTACACTAGCGGCGCGCTGATCAAAGATAAATTACTGGCAAACTTAATCGTCGACAGCAATCAACGCGATGCCTGGCGC
TCAGATTTAAAACCCACAATCGATGCGCTAGAAGACAGAGATGAAATCAGCGCCCTCGCTAACCTGCAATGGTTGATTGA
TAGCCAACAAGATCTGCAATTTGACTTAAGTTACGCCAACGACGAACGCGAGTCGGATTGGAATAACTACGGCACTATCC
TCACCAATAACCAGCAAGCCGAGCGGATAAGCTCAGGTTTAACCCACAATGGCCACTGGAATTGGGGCGATACTCGCCTG
CGCTATTACTATGAAAATGTTGAGGTGACTGACGACTCCGCGCTGATCGCCGAGATTGGGCATATCACCCAAACTAACCA
CAATCTCGACGGCCAAACCACAGTACTACTTGGGGATCACATGTTAACCAGCGGCGCGGAATACCGTTGGACTCAGCTTG
AAAACAGCCGCAATATTTTGGGTGATGGCACCTTAGACGACAGCCAGTCGGCCTTGTATCTGCAAGATGAATTTAGCTTA
GGCGAACTCAATATCACCTTAGGGGGGCGCGTCGATCACCACGATGTGTACGGCACCGAATTTAGCCCACGCGTGTATTT
GGTGTATAACTTAAGCTCTGAATGGGTGATCAAAGGTGGCGGTGGCAAGGCATTTAAAGCGCCAAATATGTCGCAATCCC
AAGCCGATTATATTATCCCCGCTTGTCGCGGCGCCTGCACCGTTGCGGGGAATCCCGATCTACAGCCCGAAACCTCAGTG
AACTACGAGTTATCGACCCAATATCAAACCACTGATTTTGGCGGCTCAATCACCTACTTCCACAACGATGTGGAAAATAA
AATCATCACAGAAACCTGGGATAGAACGCCCGGCGCAGTGTTGACTTATCAAAACGTGAACGAAGCCAAGATCACCGGTT
GGGAACTGCAGGCTTGGTACGATGTAACCGACACGGTCAGCTTTAGCGGTAATTACAGTAAAACCGATGCTGAAGATAAG
CAAAATGGCGCGCCTTTTACCCTAACGCCGGATGACAGCTACAACCTGAAACTGCAATGGCAGGCATTGGAGGGCTTATC
CACCTTTATCGCCTACCACTACACTGGCGATCAGTATTTGCGCACCAATGTAAAATCGACGGGTTATGGTTCACTCGATC
TCGGCGCAAATTACCAAATCAATCCTATGTTCAGAGTCAAACTCGGCGTCACTAACCTAACGGATACAGAACGCGACCAA
GTGGCTACTGATCTTGATTACATTCAAAAGAGCCGCAGTATTTATGCGGGCGTGACGGCAAGTTTCTAA

Upstream 100 bases:

>100_bases
GTAAAATTTACATAGTCTTTACACAAAAGCGGGATCTGCACTCTTGATGCACTATTTAAGAATAATTATCATTCGCCGAA
ATTATCCAAGGAAGAATGAT

Downstream 100 bases:

>100_bases
TAGCAATCAGCCACACACATGGGTTTATCTAGGTGAAAACGGGCTTGCGAAACTATCGCCAGCCCGTTGTTTATGAATTC
GTTGAATGCTTTCGAACTTT

Product: TonB-dependent receptor

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 662; Mature: 661

Protein sequence:

>662_residues
MSRLIRRTRKTSHTSGAALSPKLSLLSRAIGLSLLLPAAWATAAAPQDATPEMERMVITATQTQHSELSAPASVSVINRS
ELEALVIDDLASAVRYLQGVNISEGTPYGRNEISLRGLDSDYTLILINGRRVNSREALTSGYGNDFDLSSIPMSAIERIE
VVRGPMSSLYGSEALGGVVNVILRQPTDDWQTSVGVQYDTPTSGKGGDSTKYNFYTSGALIKDKLLANLIVDSNQRDAWR
SDLKPTIDALEDRDEISALANLQWLIDSQQDLQFDLSYANDERESDWNNYGTILTNNQQAERISSGLTHNGHWNWGDTRL
RYYYENVEVTDDSALIAEIGHITQTNHNLDGQTTVLLGDHMLTSGAEYRWTQLENSRNILGDGTLDDSQSALYLQDEFSL
GELNITLGGRVDHHDVYGTEFSPRVYLVYNLSSEWVIKGGGGKAFKAPNMSQSQADYIIPACRGACTVAGNPDLQPETSV
NYELSTQYQTTDFGGSITYFHNDVENKIITETWDRTPGAVLTYQNVNEAKITGWELQAWYDVTDTVSFSGNYSKTDAEDK
QNGAPFTLTPDDSYNLKLQWQALEGLSTFIAYHYTGDQYLRTNVKSTGYGSLDLGANYQINPMFRVKLGVTNLTDTERDQ
VATDLDYIQKSRSIYAGVTASF

Sequences:

>Translated_662_residues
MSRLIRRTRKTSHTSGAALSPKLSLLSRAIGLSLLLPAAWATAAAPQDATPEMERMVITATQTQHSELSAPASVSVINRS
ELEALVIDDLASAVRYLQGVNISEGTPYGRNEISLRGLDSDYTLILINGRRVNSREALTSGYGNDFDLSSIPMSAIERIE
VVRGPMSSLYGSEALGGVVNVILRQPTDDWQTSVGVQYDTPTSGKGGDSTKYNFYTSGALIKDKLLANLIVDSNQRDAWR
SDLKPTIDALEDRDEISALANLQWLIDSQQDLQFDLSYANDERESDWNNYGTILTNNQQAERISSGLTHNGHWNWGDTRL
RYYYENVEVTDDSALIAEIGHITQTNHNLDGQTTVLLGDHMLTSGAEYRWTQLENSRNILGDGTLDDSQSALYLQDEFSL
GELNITLGGRVDHHDVYGTEFSPRVYLVYNLSSEWVIKGGGGKAFKAPNMSQSQADYIIPACRGACTVAGNPDLQPETSV
NYELSTQYQTTDFGGSITYFHNDVENKIITETWDRTPGAVLTYQNVNEAKITGWELQAWYDVTDTVSFSGNYSKTDAEDK
QNGAPFTLTPDDSYNLKLQWQALEGLSTFIAYHYTGDQYLRTNVKSTGYGSLDLGANYQINPMFRVKLGVTNLTDTERDQ
VATDLDYIQKSRSIYAGVTASF
>Mature_661_residues
SRLIRRTRKTSHTSGAALSPKLSLLSRAIGLSLLLPAAWATAAAPQDATPEMERMVITATQTQHSELSAPASVSVINRSE
LEALVIDDLASAVRYLQGVNISEGTPYGRNEISLRGLDSDYTLILINGRRVNSREALTSGYGNDFDLSSIPMSAIERIEV
VRGPMSSLYGSEALGGVVNVILRQPTDDWQTSVGVQYDTPTSGKGGDSTKYNFYTSGALIKDKLLANLIVDSNQRDAWRS
DLKPTIDALEDRDEISALANLQWLIDSQQDLQFDLSYANDERESDWNNYGTILTNNQQAERISSGLTHNGHWNWGDTRLR
YYYENVEVTDDSALIAEIGHITQTNHNLDGQTTVLLGDHMLTSGAEYRWTQLENSRNILGDGTLDDSQSALYLQDEFSLG
ELNITLGGRVDHHDVYGTEFSPRVYLVYNLSSEWVIKGGGGKAFKAPNMSQSQADYIIPACRGACTVAGNPDLQPETSVN
YELSTQYQTTDFGGSITYFHNDVENKIITETWDRTPGAVLTYQNVNEAKITGWELQAWYDVTDTVSFSGNYSKTDAEDKQ
NGAPFTLTPDDSYNLKLQWQALEGLSTFIAYHYTGDQYLRTNVKSTGYGSLDLGANYQINPMFRVKLGVTNLTDTERDQV
ATDLDYIQKSRSIYAGVTASF

Specific function: Not yet known. Postulated to participate in iron transport. Outer membrane receptor for colicins IA and IB [H]

COG id: COG4771

COG function: function code P; Outer membrane receptor for ferrienterochelin and colicins

Gene ontology:

Cell location: Cell outer membrane [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the tonB-dependent receptor family [H]

Homologues:

Organism=Escherichia coli, GI1788478, Length=678, Percent_Identity=34.9557522123894, Blast_Score=328, Evalue=1e-90,
Organism=Escherichia coli, GI1786798, Length=690, Percent_Identity=26.8115942028986, Blast_Score=171, Evalue=2e-43,
Organism=Escherichia coli, GI1790405, Length=643, Percent_Identity=23.6391912908243, Blast_Score=119, Evalue=7e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012910
- InterPro:   IPR000531
- InterPro:   IPR010916
- InterPro:   IPR010917 [H]

Pfam domain/function: PF07715 Plug; PF00593 TonB_dep_Rec [H]

EC number: NA

Molecular weight: Translated: 73278; Mature: 73146

Theoretical pI: Translated: 4.42; Mature: 4.42

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRLIRRTRKTSHTSGAALSPKLSLLSRAIGLSLLLPAAWATAAAPQDATPEMERMVITA
CCHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHEEEEEE
TQTQHSELSAPASVSVINRSELEALVIDDLASAVRYLQGVNISEGTPYGRNEISLRGLDS
ECCCCCCCCCCCEEEEECHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEECCC
DYTLILINGRRVNSREALTSGYGNDFDLSSIPMSAIERIEVVRGPMSSLYGSEALGGVVN
CEEEEEEECCCCCCHHHHHCCCCCCCCCCCCCHHHHHHHHHHHCCHHHHCCHHHHHHHHH
VILRQPTDDWQTSVGVQYDTPTSGKGGDSTKYNFYTSGALIKDKLLANLIVDSNQRDAWR
HHHCCCCCHHHHCCCEEECCCCCCCCCCCCEEEEEECCCHHHHHHHHHHHCCCCCCHHHH
SDLKPTIDALEDRDEISALANLQWLIDSQQDLQFDLSYANDERESDWNNYGTILTNNQQA
HCCCHHHHHHCCHHHHHHHHCEEEEECCCCCCEEEEEECCCCCCCCCCCCCCEEECCHHH
ERISSGLTHNGHWNWGDTRLRYYYENVEVTDDSALIAEIGHITQTNHNLDGQTTVLLGDH
HHHHCCCCCCCCCCCCCCEEEEEEECEEECCCCHHHHHHCCCCCCCCCCCCCEEEEEECC
MLTSGAEYRWTQLENSRNILGDGTLDDSQSALYLQDEFSLGELNITLGGRVDHHDVYGTE
CCCCCCCEEEEEECCCCCEECCCCCCCCCCEEEEEECCCEEEEEEEECCEECCCCCCCCC
FSPRVYLVYNLSSEWVIKGGGGKAFKAPNMSQSQADYIIPACRGACTVAGNPDLQPETSV
CCCEEEEEEECCCCEEEECCCCCEEECCCCCCCCCCEEEECCCCEEEECCCCCCCCCCCC
NYELSTQYQTTDFGGSITYFHNDVENKIITETWDRTPGAVLTYQNVNEAKITGWELQAWY
CEEEECEEEECCCCCEEEEEECCCCCCEEHHHCCCCCCEEEEECCCCCCEEEEEEEEEEE
DVTDTVSFSGNYSKTDAEDKQNGAPFTLTPDDSYNLKLQWQALEGLSTFIAYHYTGDQYL
EECEEEEECCCCCCCCCCHHCCCCCEEECCCCCCEEEEEEEHHHCCEEEEEEEECCCHHE
RTNVKSTGYGSLDLGANYQINPMFRVKLGVTNLTDTERDQVATDLDYIQKSRSIYAGVTA
EECCCCCCCCCEECCCCEEECEEEEEEEECCCCCCCCHHHHHHHHHHHHHCCCEEEEEEE
SF
CC
>Mature Secondary Structure 
SRLIRRTRKTSHTSGAALSPKLSLLSRAIGLSLLLPAAWATAAAPQDATPEMERMVITA
CHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHEEEEEE
TQTQHSELSAPASVSVINRSELEALVIDDLASAVRYLQGVNISEGTPYGRNEISLRGLDS
ECCCCCCCCCCCEEEEECHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEECCC
DYTLILINGRRVNSREALTSGYGNDFDLSSIPMSAIERIEVVRGPMSSLYGSEALGGVVN
CEEEEEEECCCCCCHHHHHCCCCCCCCCCCCCHHHHHHHHHHHCCHHHHCCHHHHHHHHH
VILRQPTDDWQTSVGVQYDTPTSGKGGDSTKYNFYTSGALIKDKLLANLIVDSNQRDAWR
HHHCCCCCHHHHCCCEEECCCCCCCCCCCCEEEEEECCCHHHHHHHHHHHCCCCCCHHHH
SDLKPTIDALEDRDEISALANLQWLIDSQQDLQFDLSYANDERESDWNNYGTILTNNQQA
HCCCHHHHHHCCHHHHHHHHCEEEEECCCCCCEEEEEECCCCCCCCCCCCCCEEECCHHH
ERISSGLTHNGHWNWGDTRLRYYYENVEVTDDSALIAEIGHITQTNHNLDGQTTVLLGDH
HHHHCCCCCCCCCCCCCCEEEEEEECEEECCCCHHHHHHCCCCCCCCCCCCCEEEEEECC
MLTSGAEYRWTQLENSRNILGDGTLDDSQSALYLQDEFSLGELNITLGGRVDHHDVYGTE
CCCCCCCEEEEEECCCCCEECCCCCCCCCCEEEEEECCCEEEEEEEECCEECCCCCCCCC
FSPRVYLVYNLSSEWVIKGGGGKAFKAPNMSQSQADYIIPACRGACTVAGNPDLQPETSV
CCCEEEEEEECCCCEEEECCCCCEEECCCCCCCCCCEEEECCCCEEEECCCCCCCCCCCC
NYELSTQYQTTDFGGSITYFHNDVENKIITETWDRTPGAVLTYQNVNEAKITGWELQAWY
CEEEECEEEECCCCCEEEEEECCCCCCEEHHHCCCCCCEEEEECCCCCCEEEEEEEEEEE
DVTDTVSFSGNYSKTDAEDKQNGAPFTLTPDDSYNLKLQWQALEGLSTFIAYHYTGDQYL
EECEEEEECCCCCCCCCCHHCCCCCEEECCCCCCEEEEEEEHHHCCEEEEEEEECCCHHE
RTNVKSTGYGSLDLGANYQINPMFRVKLGVTNLTDTERDQVATDLDYIQKSRSIYAGVTA
EECCCCCCCCCEECCCCEEECEEEEEEEECCCCCCCCHHHHHHHHHHHHHCCCEEEEEEE
SF
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2644220; 9278503; 3316180; 1315732; 2160948 [H]