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The map label for this gene is fixB [H]

Identifier: 227828787

GI number: 227828787

Start: 2379908

End: 2380771

Strand: Direct

Name: fixB [H]

Synonym: M1425_2561

Alternate gene names: 227828787

Gene position: 2379908-2380771 (Clockwise)

Preceding gene: 227828786

Following gene: 227828788

Centisome position: 91.23

GC content: 38.89

Gene sequence:

>864_bases
ATGAAAGCTGTAGTGTTTTCGGAAAGTCCAGTATTCTTAAAAATGGCAGCAGCTGTAGCTCAAAGCTTCGGAGGAGAAGT
AATAGGAATATCCGACAACGAGAACGTTAAGTTCGTAAACAAACTATACATTATTGATAAAATGGATGAAGATGGTATTG
TAGATCTAATATCTTCACTCTCTCCAGATGTAATACTAACTGGAAATGTGAGAAGGGATAGGGCAATAGCTGGAAGAGTA
GCGGGGAGGTTAAAGTTACCTATAGTTACTGATGTAGTCTCACTAAAGGTTGAAGATAAGAAAATCACGTTAAATAGGGT
AGCCTATAGTGGAATGGGGTTGGTTACTCTAGAGAGCGAGTTACCAATTGTTATAACTATTGCAAATGCACAATTACAAC
CTAAGGAACTTCAGCCTAGTGTAGAGAAGGTTCAATTGAAAGAGGGTAGGGTTAAAATTGCCGGTAGGAAATCAACTTCC
TCTGGAGTTAATTTAGCTACTGCAGATATTGTAGTTGGCGTAGGAAGAGGGATTGGATCTAAGGAAAACGTAAAATACGC
AGAAGAATTGGCAAAAGCGTTAGGTGGAGCAGTTGGTGGAAGCAGACCGGTAGCTGCTGAGCTCAATTGGGTTTCAGAAG
ATAGGCAAATAGGTTTATCCGGTTTAAGAATTAGGCCCAAATTATATATAGCCTTGGGAATATCTGGTCAGCCTCAACAT
ATAGCTGGTATAAGGGATTCGAAAATTATAGTTGCTGTTAATACTGATAAGAATGCACCAATACTTGAAAACGCGGATTA
CTTGGTTGTAGGCAACGCAATCGATTTCTGTAAAGTTATGTTAAGTAAGCTAGGGAAAAAATAA

Upstream 100 bases:

>100_bases
ATGATCGTGAATCGAAAGAGAATAGTTATTGAGGAAAGTGACATAAATAAGGCGGTTGATAAATTAATTGAATATTTAAA
GTCTGATGGGGTGATCTAGT

Downstream 100 bases:

>100_bases
TAATGATAAAAACGATTTTATTTTATGGTATTTCCTTTTAAGTCCTTGGAGGATTTTAAAGTAGAAATAACGCAAGATCA
TGAATTATTAAGAAGTGCAG

Product: electron transfer flavoprotein subunit alpha

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 287; Mature: 287

Protein sequence:

>287_residues
MKAVVFSESPVFLKMAAAVAQSFGGEVIGISDNENVKFVNKLYIIDKMDEDGIVDLISSLSPDVILTGNVRRDRAIAGRV
AGRLKLPIVTDVVSLKVEDKKITLNRVAYSGMGLVTLESELPIVITIANAQLQPKELQPSVEKVQLKEGRVKIAGRKSTS
SGVNLATADIVVGVGRGIGSKENVKYAEELAKALGGAVGGSRPVAAELNWVSEDRQIGLSGLRIRPKLYIALGISGQPQH
IAGIRDSKIIVAVNTDKNAPILENADYLVVGNAIDFCKVMLSKLGKK

Sequences:

>Translated_287_residues
MKAVVFSESPVFLKMAAAVAQSFGGEVIGISDNENVKFVNKLYIIDKMDEDGIVDLISSLSPDVILTGNVRRDRAIAGRV
AGRLKLPIVTDVVSLKVEDKKITLNRVAYSGMGLVTLESELPIVITIANAQLQPKELQPSVEKVQLKEGRVKIAGRKSTS
SGVNLATADIVVGVGRGIGSKENVKYAEELAKALGGAVGGSRPVAAELNWVSEDRQIGLSGLRIRPKLYIALGISGQPQH
IAGIRDSKIIVAVNTDKNAPILENADYLVVGNAIDFCKVMLSKLGKK
>Mature_287_residues
MKAVVFSESPVFLKMAAAVAQSFGGEVIGISDNENVKFVNKLYIIDKMDEDGIVDLISSLSPDVILTGNVRRDRAIAGRV
AGRLKLPIVTDVVSLKVEDKKITLNRVAYSGMGLVTLESELPIVITIANAQLQPKELQPSVEKVQLKEGRVKIAGRKSTS
SGVNLATADIVVGVGRGIGSKENVKYAEELAKALGGAVGGSRPVAAELNWVSEDRQIGLSGLRIRPKLYIALGISGQPQH
IAGIRDSKIIVAVNTDKNAPILENADYLVVGNAIDFCKVMLSKLGKK

Specific function: Required for anaerobic carnitine reduction. May bring reductant to CaiA [H]

COG id: COG2025

COG function: function code C; Electron transfer flavoprotein, alpha subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ETF alpha-subunit/fixB family [H]

Homologues:

Organism=Homo sapiens, GI189181759, Length=219, Percent_Identity=34.703196347032, Blast_Score=109, Evalue=3e-24,
Organism=Homo sapiens, GI4503607, Length=219, Percent_Identity=34.703196347032, Blast_Score=109, Evalue=3e-24,
Organism=Escherichia coli, GI1786226, Length=305, Percent_Identity=33.1147540983607, Blast_Score=155, Evalue=3e-39,
Organism=Escherichia coli, GI1787990, Length=304, Percent_Identity=32.2368421052632, Blast_Score=147, Evalue=9e-37,
Organism=Escherichia coli, GI87082157, Length=244, Percent_Identity=31.1475409836066, Blast_Score=62, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI17506929, Length=213, Percent_Identity=37.0892018779343, Blast_Score=114, Evalue=5e-26,
Organism=Saccharomyces cerevisiae, GI6325261, Length=224, Percent_Identity=32.5892857142857, Blast_Score=87, Evalue=2e-18,
Organism=Drosophila melanogaster, GI17136898, Length=216, Percent_Identity=35.1851851851852, Blast_Score=109, Evalue=2e-24,
Organism=Drosophila melanogaster, GI24652801, Length=216, Percent_Identity=35.1851851851852, Blast_Score=109, Evalue=2e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001308
- InterPro:   IPR014730
- InterPro:   IPR014731
- InterPro:   IPR018206
- InterPro:   IPR014729 [H]

Pfam domain/function: PF01012 ETF; PF00766 ETF_alpha [H]

EC number: NA

Molecular weight: Translated: 30581; Mature: 30581

Theoretical pI: Translated: 9.95; Mature: 9.95

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKAVVFSESPVFLKMAAAVAQSFGGEVIGISDNENVKFVNKLYIIDKMDEDGIVDLISSL
CCEEEECCCCHHHHHHHHHHHHHCCCEEEECCCCCEEEEEEEEEEEECCCCCHHHHHHHC
SPDVILTGNVRRDRAIAGRVAGRLKLPIVTDVVSLKVEDKKITLNRVAYSGMGLVTLESE
CCCEEEECCCCCCHHHHHHHCCEEECCEEEEEEEEEEECCEEEEEEEEECCCEEEEECCC
LPIVITIANAQLQPKELQPSVEKVQLKEGRVKIAGRKSTSSGVNLATADIVVGVGRGIGS
CCEEEEEECCCCCCHHCCCCHHEEEECCCEEEEEECCCCCCCCEEEEEEEEEECCCCCCC
KENVKYAEELAKALGGAVGGSRPVAAELNWVSEDRQIGLSGLRIRPKLYIALGISGQPQH
CCCHHHHHHHHHHHCCCCCCCCCEEEEEEECCCCCCCCCCCEEECCEEEEEEECCCCCCC
IAGIRDSKIIVAVNTDKNAPILENADYLVVGNAIDFCKVMLSKLGKK
EECCCCCEEEEEEECCCCCCEECCCCEEEECCHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKAVVFSESPVFLKMAAAVAQSFGGEVIGISDNENVKFVNKLYIIDKMDEDGIVDLISSL
CCEEEECCCCHHHHHHHHHHHHHCCCEEEECCCCCEEEEEEEEEEEECCCCCHHHHHHHC
SPDVILTGNVRRDRAIAGRVAGRLKLPIVTDVVSLKVEDKKITLNRVAYSGMGLVTLESE
CCCEEEECCCCCCHHHHHHHCCEEECCEEEEEEEEEEECCEEEEEEEEECCCEEEEECCC
LPIVITIANAQLQPKELQPSVEKVQLKEGRVKIAGRKSTSSGVNLATADIVVGVGRGIGS
CCEEEEEECCCCCCHHCCCCHHEEEECCCEEEEEECCCCCCCCEEEEEEEEEECCCCCCC
KENVKYAEELAKALGGAVGGSRPVAAELNWVSEDRQIGLSGLRIRPKLYIALGISGQPQH
CCCHHHHHHHHHHHCCCCCCCCCEEEEEEECCCCCCCCCCCEEECCEEEEEEECCCCCCC
IAGIRDSKIIVAVNTDKNAPILENADYLVVGNAIDFCKVMLSKLGKK
EECCCCCEEEEEEECCCCCCEECCCCEEEECCHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA