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The map label for this gene is rspB [C]

Identifier: 227828600

GI number: 227828600

Start: 2183584

End: 2184684

Strand: Direct

Name: rspB [C]

Synonym: M1425_2353

Alternate gene names: 227828600

Gene position: 2183584-2184684 (Clockwise)

Preceding gene: 227828598

Following gene: 227828601

Centisome position: 83.7

GC content: 37.51

Gene sequence:

>1101_bases
ATGAAAGCTATAATAGTGAAACCCCCAAATGCAGGAGTGCAGATCAAGGACGTCGATGAAAAGAAATTAGATAGTTACGG
GAAACTAAGGATAAGAACTATCTATAACGGTATTTGCGGTACTGATAGAGAGATAGTTAATGGCAAGTTAACATTATCAA
CTCTACCTAAGGGAAAGGATTTCTTAGTGTTAGGTCATGAGGCAATAGGCGTTGTAGAAGAGTCTTATTACGGTTTTTCT
CAAGGAGATCTGGTAATGCCAGTTAATAGGAGAGGATGCGGTATTTGTAGAAATTGTTTGGTAGGAAGACCAGACTTTTG
CGAAACAGGTGAATTTGGAGAGGCTGGAATACACAAAATGGATGGGTTTATGAGGGAATGGTGGTACGATGATCCTAAGT
ATTTGGTTAGAATTCCCAAGTCAATAGAAGATATTGGAATTTTAGCTCAACCATTAGCTGACATCGAGAAATCCATTGAG
GAAATATTGGAAGTTCAGAAGAGGGTTCCAGTATGGACGTGTGATGATGGGACTTTGAATTGTAGAAAGGTTTTAGTTGT
AGGTACGGGACCAATTGGCATACTATTTACTCTGCTTTTCAGAACTTATGGATTAGAAGTCTGGGTATCAAATAGAAGAG
AACCAACTGAAGTTGAGCAAATTGTCATAGAGGAAACCAAGACTAACTTCTATAACTCAGCCAATGGATACGATAAATTG
AAAGAATCTGTAGGTAAGTTCGATGTGATTATAGACGCTACTGGGGCCGATGTAAATATATTAAGTAATGTTATTCCATT
GTTAGGAAGGAATGGAGTTTTAGGTCTCTTTGGATTCTCAACTTCCGGTTCAGTTCCACTTGACTATAAGACATTACAAG
AAATAGTACATGCAAATAAGACGATAATAGGTTTGGTAAACGGTCAGAAGCCCCACTTTCAGCAAGCTGTAGTTCATTTA
GCCTCTTGGAAGACTTTGTATCCTAAGACTTCTAAGATGTTACTCACTAAGACTGTGAGTATAAATGATGAAAAGGAATT
ACTTAAGGTGCTAAAGGAAAAGGAACGTGGAGAAATTAAGATAAGAATATTATGGGAATAA

Upstream 100 bases:

>100_bases
ATTTTGAGGTATACTGTCTTAGAAATTTACGTAGGTTTAAAAATTTTTAAGTTATATTGGGCATAAAGTTTATATCTTTC
CCACCTTAACATAGCTTTTA

Downstream 100 bases:

>100_bases
TACAATAAAAGTCCAAGTTTTTTATATCAGAACTTTTGAGTGTAGATAGGTTCCACTTATGGTATATCTAATATGACAGT
ACTTGAATTAGATTTTAAGG

Product: alcohol dehydrogenase GroES domain protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 366; Mature: 366

Protein sequence:

>366_residues
MKAIIVKPPNAGVQIKDVDEKKLDSYGKLRIRTIYNGICGTDREIVNGKLTLSTLPKGKDFLVLGHEAIGVVEESYYGFS
QGDLVMPVNRRGCGICRNCLVGRPDFCETGEFGEAGIHKMDGFMREWWYDDPKYLVRIPKSIEDIGILAQPLADIEKSIE
EILEVQKRVPVWTCDDGTLNCRKVLVVGTGPIGILFTLLFRTYGLEVWVSNRREPTEVEQIVIEETKTNFYNSANGYDKL
KESVGKFDVIIDATGADVNILSNVIPLLGRNGVLGLFGFSTSGSVPLDYKTLQEIVHANKTIIGLVNGQKPHFQQAVVHL
ASWKTLYPKTSKMLLTKTVSINDEKELLKVLKEKERGEIKIRILWE

Sequences:

>Translated_366_residues
MKAIIVKPPNAGVQIKDVDEKKLDSYGKLRIRTIYNGICGTDREIVNGKLTLSTLPKGKDFLVLGHEAIGVVEESYYGFS
QGDLVMPVNRRGCGICRNCLVGRPDFCETGEFGEAGIHKMDGFMREWWYDDPKYLVRIPKSIEDIGILAQPLADIEKSIE
EILEVQKRVPVWTCDDGTLNCRKVLVVGTGPIGILFTLLFRTYGLEVWVSNRREPTEVEQIVIEETKTNFYNSANGYDKL
KESVGKFDVIIDATGADVNILSNVIPLLGRNGVLGLFGFSTSGSVPLDYKTLQEIVHANKTIIGLVNGQKPHFQQAVVHL
ASWKTLYPKTSKMLLTKTVSINDEKELLKVLKEKERGEIKIRILWE
>Mature_366_residues
MKAIIVKPPNAGVQIKDVDEKKLDSYGKLRIRTIYNGICGTDREIVNGKLTLSTLPKGKDFLVLGHEAIGVVEESYYGFS
QGDLVMPVNRRGCGICRNCLVGRPDFCETGEFGEAGIHKMDGFMREWWYDDPKYLVRIPKSIEDIGILAQPLADIEKSIE
EILEVQKRVPVWTCDDGTLNCRKVLVVGTGPIGILFTLLFRTYGLEVWVSNRREPTEVEQIVIEETKTNFYNSANGYDKL
KESVGKFDVIIDATGADVNILSNVIPLLGRNGVLGLFGFSTSGSVPLDYKTLQEIVHANKTIIGLVNGQKPHFQQAVVHL
ASWKTLYPKTSKMLLTKTVSINDEKELLKVLKEKERGEIKIRILWE

Specific function: Not Known; Probable Catabolic Enzyme. [C]

COG id: COG1063

COG function: function code ER; Threonine dehydrogenase and related Zn-dependent dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1787863, Length=291, Percent_Identity=25.7731958762887, Blast_Score=67, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013154
- InterPro:   IPR002085
- InterPro:   IPR011032
- InterPro:   IPR016040 [H]

Pfam domain/function: PF08240 ADH_N [H]

EC number: =1.1.1.47 [H]

Molecular weight: Translated: 41017; Mature: 41017

Theoretical pI: Translated: 7.39; Mature: 7.39

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKAIIVKPPNAGVQIKDVDEKKLDSYGKLRIRTIYNGICGTDREIVNGKLTLSTLPKGKD
CCEEEEECCCCCEEEEECCHHHHCCCCCEEEEEEECCCCCCCHHHHCCEEEEEECCCCCC
FLVLGHEAIGVVEESYYGFSQGDLVMPVNRRGCGICRNCLVGRPDFCETGEFGEAGIHKM
EEEECCHHHHHHHHHCCCCCCCCEEEECCCCCCHHHHHHCCCCCCCCCCCCCCCCHHHHH
DGFMREWWYDDPKYLVRIPKSIEDIGILAQPLADIEKSIEEILEVQKRVPVWTCDDGTLN
HHHHHHHCCCCCHHEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCCCC
CRKVLVVGTGPIGILFTLLFRTYGLEVWVSNRREPTEVEQIVIEETKTNFYNSANGYDKL
EEEEEEEECCHHHHHHHHHHHHHCEEEEECCCCCCHHHHHHHHHHHHCCCCCCCCCHHHH
KESVGKFDVIIDATGADVNILSNVIPLLGRNGVLGLFGFSTSGSVPLDYKTLQEIVHANK
HHHCCCEEEEEECCCCCHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCHHHHHHHHHCCC
TIIGLVNGQKPHFQQAVVHLASWKTLYPKTSKMLLTKTVSINDEKELLKVLKEKERGEIK
EEEEEECCCCCHHHHHHHHHHHCCEECCCCCCEEEEEEECCCCHHHHHHHHHHCCCCCEE
IRILWE
EEEEEC
>Mature Secondary Structure
MKAIIVKPPNAGVQIKDVDEKKLDSYGKLRIRTIYNGICGTDREIVNGKLTLSTLPKGKD
CCEEEEECCCCCEEEEECCHHHHCCCCCEEEEEEECCCCCCCHHHHCCEEEEEECCCCCC
FLVLGHEAIGVVEESYYGFSQGDLVMPVNRRGCGICRNCLVGRPDFCETGEFGEAGIHKM
EEEECCHHHHHHHHHCCCCCCCCEEEECCCCCCHHHHHHCCCCCCCCCCCCCCCCHHHHH
DGFMREWWYDDPKYLVRIPKSIEDIGILAQPLADIEKSIEEILEVQKRVPVWTCDDGTLN
HHHHHHHCCCCCHHEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCCCC
CRKVLVVGTGPIGILFTLLFRTYGLEVWVSNRREPTEVEQIVIEETKTNFYNSANGYDKL
EEEEEEEECCHHHHHHHHHHHHHCEEEEECCCCCCHHHHHHHHHHHHCCCCCCCCCHHHH
KESVGKFDVIIDATGADVNILSNVIPLLGRNGVLGLFGFSTSGSVPLDYKTLQEIVHANK
HHHCCCEEEEEECCCCCHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCHHHHHHHHHCCC
TIIGLVNGQKPHFQQAVVHLASWKTLYPKTSKMLLTKTVSINDEKELLKVLKEKERGEIK
EEEEEECCCCCHHHHHHHHHHHCCEECCCCCCEEEEEEECCCCHHHHHHHHHHCCCCCEE
IRILWE
EEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8436115; 11029001; 2803257 [H]