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The map label for this gene is xylS [H]

Identifier: 227828582

GI number: 227828582

Start: 2156593

End: 2158785

Strand: Direct

Name: xylS [H]

Synonym: M1425_2336

Alternate gene names: 227828582

Gene position: 2156593-2158785 (Clockwise)

Preceding gene: 227828580

Following gene: 227828583

Centisome position: 82.67

GC content: 39.31

Gene sequence:

>2193_bases
ATGAGAATAAGGAATTTTAATGTGGAAATAGAATTTATCGCAGATAATATTGTCAGAGTTTTGTACTATTATGGAAGGGA
AGCCATAATAGATAATAGTCTAGTTGTATTACCGAACCTAGAGAAGCTAAGCATTAAAGGGGAAAGTACGAGTCCATCTA
TAATCTCTTTGTCCAGTAAATCTCTCAGTGTAGATATAAACACTTCTAACGGAGAGTTAATAATAAAGGACAACAAGGGG
GGAATTGTTGTTAAGGAGAAGAGAAGGAATTTGAAATTTAACGAGGAGTTATCAACTTACAACGTTGAGCAAGAGTTTGG
GTTGAGTGAGGGTGAAAGATTATATGGCTTGGGACAACATGCAGGAGGAAATGGTTTAGGTCAATCCTCAGCCTACAAGT
TAGACTATAATGGTCTTTCCATCACGTTGTCTCAGAGAAATACTGATATCGGCATTCCATTCATGATTTCTAGTAAAGGT
TATGGAATATTGTGGGATAACTATTCCCTAGGATCAATAAGTCTTAAGGGGAACGAATTGAGGGTTTGGTTTGAAGCTGG
TAAAAAGATAGACTACTACGTAATTTTCGGTGACTCCATAGACGATGTGATAAAGGGTTATAGGAAGTTGACTGGAGATG
CCCCTCTCTTACCTAAATGGGCTTATGGGTATTGGCAGAGTAAGGAAAGGTATAAGTCACAAGATGAGTTAGTAAGCGTA
GTTAAGGAGTTTAGAGAAAGGAAGATACCCCTAGATGTAATAGTGCTAGACTGGCGGTATTGGGGAAAATATGGGTGGAA
CGCTTTCAAATTTGATGAGATAGATTTTCCGAGACCTAAAGATATGGTCGAGGAAATTCATAAAATGGGAGCTAAGTTGG
CAATATCAATATGGCCCACTTTTGGGAAGGAGACTGAAGTGTTTAAGAATATGGAGAGTAAAGGGTGTATAATTCCGGGG
ACTACAGCAGTTAATCCCTTTAAGGAGGGATGTAGAGAGCTTTTCTGGAGTTACGTAAAGAGGTTTTACGATATAGGAAT
AGATGCCTATTGGTTAGATGCCTCAGAGCCCGAAACTGGACTAGGCTTAGTCTTCTTCTCCCCAATTCATGATGTGGATT
TAGGAATTGGAAAAGGATATGAACATTTGAACGCTTACCCATTAATGGAAACTAAGGCTGTTTATGAGGGGCAACGGAGA
ATTAGTGATAAAAGAGTTGCAATATTGACTAGATCTGCATTTGCCGGTCAACAGAGGTATTCAGCAATAAGTTGGTCTGG
GGATGTATTAGGGGATTGGGCTACATTGAGGTCTCAAATTCCCGCTGGTCTTAACTTTTCAATTTCTGGCATACCCTACT
GGACTACTGATACTGGTGGATTCTTCTCTGGAAATCCGGAAACTAAGGCTTACGCAGAGATTTTCGTTAGGTGGTTCCAG
TGGAGCACTTTTTGCCCTATACTTAGAGTTCACGGTACAATATTTCCTAAGGAGCCGTGGAGATTTCCAAAGGAATATCA
AGACGTTATCCTTAAGTATATAAGGCTTAGATACGAATTACTTCCTTACATTTACTCATTGGCATGGATGACGTATAGCA
ATGGATACACAATTATGAGACCACTAGTTATGGATTTTCGTAACGACAAAAACGTTTACGATCTTGATGAACAATACATG
TTTGGTCCTTATATAATGGTATCCCCAGTAACATTGCCAAGTATTAGAGAAAAAGAGGTTTACTTACCCTCTGACGAGTA
TTGGTATGACTTCTGGACTGGTGAGAAGTTGAAAGGAGGAAGAACAACAAACGTTAAAGTTTCATTAGGTACAATACCCC
TATTTGTGAGAGGTGGTGCCGTTCTACCATTATTGGGAAAAGATGTGAGTAATGCAATGGAGGACTGGGATGTACTTCAC
TTAAGGATATATCCAGGTAAGGATGGTTACTTCGAAATATACGATGACGATGGTGTTACGTATGATTACGAAAGGGGAAA
GTACTTTATCGTACCTATCAGATGGGATGATAATAAGCAAGAGCTCACCATAGGAAAGAAAAGAGGAGACCTAGAGATGA
GGAAGAGAATCATGATAACTTGGGTTGAAAAAGGTAAGGGTATTGAGTACTCGAAGCCAGACGTGGAGGTAGAATATGAT
GGTAAGGAAAGTATTACGGTTAAAAGACATTAG

Upstream 100 bases:

>100_bases
AAATCTCCTTAAGTATTATAATAACATATACTTCTCTCATTATAGAAGGGGAAGGTAAATACCACAAATCTTATATAATA
GCTCATGAAGAAGCTCTATA

Downstream 100 bases:

>100_bases
TATTTTTATTTTATTATTCTTTTGTCTTAACAATGAAGGAATTCAAGTTAGCCGTTTACGTTACAGCCCCAACTCTAAAG
AGTCTAAATGAAGAAAGGAC

Product: alpha-glucosidase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 730; Mature: 730

Protein sequence:

>730_residues
MRIRNFNVEIEFIADNIVRVLYYYGREAIIDNSLVVLPNLEKLSIKGESTSPSIISLSSKSLSVDINTSNGELIIKDNKG
GIVVKEKRRNLKFNEELSTYNVEQEFGLSEGERLYGLGQHAGGNGLGQSSAYKLDYNGLSITLSQRNTDIGIPFMISSKG
YGILWDNYSLGSISLKGNELRVWFEAGKKIDYYVIFGDSIDDVIKGYRKLTGDAPLLPKWAYGYWQSKERYKSQDELVSV
VKEFRERKIPLDVIVLDWRYWGKYGWNAFKFDEIDFPRPKDMVEEIHKMGAKLAISIWPTFGKETEVFKNMESKGCIIPG
TTAVNPFKEGCRELFWSYVKRFYDIGIDAYWLDASEPETGLGLVFFSPIHDVDLGIGKGYEHLNAYPLMETKAVYEGQRR
ISDKRVAILTRSAFAGQQRYSAISWSGDVLGDWATLRSQIPAGLNFSISGIPYWTTDTGGFFSGNPETKAYAEIFVRWFQ
WSTFCPILRVHGTIFPKEPWRFPKEYQDVILKYIRLRYELLPYIYSLAWMTYSNGYTIMRPLVMDFRNDKNVYDLDEQYM
FGPYIMVSPVTLPSIREKEVYLPSDEYWYDFWTGEKLKGGRTTNVKVSLGTIPLFVRGGAVLPLLGKDVSNAMEDWDVLH
LRIYPGKDGYFEIYDDDGVTYDYERGKYFIVPIRWDDNKQELTIGKKRGDLEMRKRIMITWVEKGKGIEYSKPDVEVEYD
GKESITVKRH

Sequences:

>Translated_730_residues
MRIRNFNVEIEFIADNIVRVLYYYGREAIIDNSLVVLPNLEKLSIKGESTSPSIISLSSKSLSVDINTSNGELIIKDNKG
GIVVKEKRRNLKFNEELSTYNVEQEFGLSEGERLYGLGQHAGGNGLGQSSAYKLDYNGLSITLSQRNTDIGIPFMISSKG
YGILWDNYSLGSISLKGNELRVWFEAGKKIDYYVIFGDSIDDVIKGYRKLTGDAPLLPKWAYGYWQSKERYKSQDELVSV
VKEFRERKIPLDVIVLDWRYWGKYGWNAFKFDEIDFPRPKDMVEEIHKMGAKLAISIWPTFGKETEVFKNMESKGCIIPG
TTAVNPFKEGCRELFWSYVKRFYDIGIDAYWLDASEPETGLGLVFFSPIHDVDLGIGKGYEHLNAYPLMETKAVYEGQRR
ISDKRVAILTRSAFAGQQRYSAISWSGDVLGDWATLRSQIPAGLNFSISGIPYWTTDTGGFFSGNPETKAYAEIFVRWFQ
WSTFCPILRVHGTIFPKEPWRFPKEYQDVILKYIRLRYELLPYIYSLAWMTYSNGYTIMRPLVMDFRNDKNVYDLDEQYM
FGPYIMVSPVTLPSIREKEVYLPSDEYWYDFWTGEKLKGGRTTNVKVSLGTIPLFVRGGAVLPLLGKDVSNAMEDWDVLH
LRIYPGKDGYFEIYDDDGVTYDYERGKYFIVPIRWDDNKQELTIGKKRGDLEMRKRIMITWVEKGKGIEYSKPDVEVEYD
GKESITVKRH
>Mature_730_residues
MRIRNFNVEIEFIADNIVRVLYYYGREAIIDNSLVVLPNLEKLSIKGESTSPSIISLSSKSLSVDINTSNGELIIKDNKG
GIVVKEKRRNLKFNEELSTYNVEQEFGLSEGERLYGLGQHAGGNGLGQSSAYKLDYNGLSITLSQRNTDIGIPFMISSKG
YGILWDNYSLGSISLKGNELRVWFEAGKKIDYYVIFGDSIDDVIKGYRKLTGDAPLLPKWAYGYWQSKERYKSQDELVSV
VKEFRERKIPLDVIVLDWRYWGKYGWNAFKFDEIDFPRPKDMVEEIHKMGAKLAISIWPTFGKETEVFKNMESKGCIIPG
TTAVNPFKEGCRELFWSYVKRFYDIGIDAYWLDASEPETGLGLVFFSPIHDVDLGIGKGYEHLNAYPLMETKAVYEGQRR
ISDKRVAILTRSAFAGQQRYSAISWSGDVLGDWATLRSQIPAGLNFSISGIPYWTTDTGGFFSGNPETKAYAEIFVRWFQ
WSTFCPILRVHGTIFPKEPWRFPKEYQDVILKYIRLRYELLPYIYSLAWMTYSNGYTIMRPLVMDFRNDKNVYDLDEQYM
FGPYIMVSPVTLPSIREKEVYLPSDEYWYDFWTGEKLKGGRTTNVKVSLGTIPLFVRGGAVLPLLGKDVSNAMEDWDVLH
LRIYPGKDGYFEIYDDDGVTYDYERGKYFIVPIRWDDNKQELTIGKKRGDLEMRKRIMITWVEKGKGIEYSKPDVEVEYD
GKESITVKRH

Specific function: Catalyzes the liberation of alpha-xylose from the non- reducing terminal glucose of xyloglucan oligosaccharides. Has high hydrolytic activity on the disaccharide isoprimeverose. Follows a retaining mechanism of substrate hydrolysis [H]

COG id: COG1501

COG function: function code G; Alpha-glucosidases, family 31 of glycosyl hydrolases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyl hydrolase 31 family [H]

Homologues:

Organism=Homo sapiens, GI66346737, Length=710, Percent_Identity=30.4225352112676, Blast_Score=249, Evalue=8e-66,
Organism=Homo sapiens, GI88900491, Length=635, Percent_Identity=28.6614173228346, Blast_Score=229, Evalue=1e-59,
Organism=Homo sapiens, GI38202257, Length=635, Percent_Identity=28.6614173228346, Blast_Score=228, Evalue=2e-59,
Organism=Homo sapiens, GI221316699, Length=706, Percent_Identity=25.070821529745, Blast_Score=178, Evalue=2e-44,
Organism=Homo sapiens, GI119393895, Length=578, Percent_Identity=25.7785467128028, Blast_Score=172, Evalue=8e-43,
Organism=Homo sapiens, GI119393893, Length=578, Percent_Identity=25.7785467128028, Blast_Score=172, Evalue=8e-43,
Organism=Homo sapiens, GI119393891, Length=578, Percent_Identity=25.7785467128028, Blast_Score=172, Evalue=8e-43,
Organism=Homo sapiens, GI157364974, Length=589, Percent_Identity=26.3157894736842, Blast_Score=155, Evalue=1e-37,
Organism=Homo sapiens, GI310115361, Length=291, Percent_Identity=31.2714776632302, Blast_Score=141, Evalue=3e-33,
Organism=Homo sapiens, GI153791946, Length=390, Percent_Identity=25.1282051282051, Blast_Score=82, Evalue=3e-15,
Organism=Escherichia coli, GI2367256, Length=597, Percent_Identity=24.7906197654941, Blast_Score=195, Evalue=7e-51,
Organism=Escherichia coli, GI2367323, Length=242, Percent_Identity=30.9917355371901, Blast_Score=123, Evalue=5e-29,
Organism=Caenorhabditis elegans, GI17560798, Length=807, Percent_Identity=27.3853779429988, Blast_Score=229, Evalue=3e-60,
Organism=Caenorhabditis elegans, GI17560800, Length=807, Percent_Identity=27.3853779429988, Blast_Score=229, Evalue=3e-60,
Organism=Caenorhabditis elegans, GI71991189, Length=528, Percent_Identity=31.8181818181818, Blast_Score=222, Evalue=5e-58,
Organism=Caenorhabditis elegans, GI32563849, Length=307, Percent_Identity=29.3159609120521, Blast_Score=125, Evalue=6e-29,
Organism=Caenorhabditis elegans, GI71985706, Length=250, Percent_Identity=30.4, Blast_Score=122, Evalue=5e-28,
Organism=Saccharomyces cerevisiae, GI6319706, Length=623, Percent_Identity=27.2873194221509, Blast_Score=195, Evalue=2e-50,
Organism=Drosophila melanogaster, GI24643749, Length=680, Percent_Identity=26.0294117647059, Blast_Score=191, Evalue=1e-48,
Organism=Drosophila melanogaster, GI24643753, Length=680, Percent_Identity=26.0294117647059, Blast_Score=191, Evalue=1e-48,
Organism=Drosophila melanogaster, GI24643751, Length=680, Percent_Identity=26.0294117647059, Blast_Score=191, Evalue=1e-48,
Organism=Drosophila melanogaster, GI24643746, Length=680, Percent_Identity=26.0294117647059, Blast_Score=191, Evalue=1e-48,
Organism=Drosophila melanogaster, GI21357605, Length=680, Percent_Identity=26.0294117647059, Blast_Score=191, Evalue=1e-48,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011013
- InterPro:   IPR000322
- InterPro:   IPR017853 [H]

Pfam domain/function: PF01055 Glyco_hydro_31 [H]

EC number: NA

Molecular weight: Translated: 84207; Mature: 84207

Theoretical pI: Translated: 6.26; Mature: 6.26

Prosite motif: PS00430 TONB_DEPENDENT_REC_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRIRNFNVEIEFIADNIVRVLYYYGREAIIDNSLVVLPNLEKLSIKGESTSPSIISLSSK
CEEEEEEEEEEEEHHHHHHHHHHHCCCEEECCCEEEEECCEEEEEECCCCCCCEEEECCC
SLSVDINTSNGELIIKDNKGGIVVKEKRRNLKFNEELSTYNVEQEFGLSEGERLYGLGQH
EEEEEEECCCCEEEEEECCCCEEEECCCCCCCCCCCCCEECCHHHCCCCCCCEEEEECCC
AGGNGLGQSSAYKLDYNGLSITLSQRNTDIGIPFMISSKGYGILWDNYSLGSISLKGNEL
CCCCCCCCCCEEEEECCCEEEEEECCCCCCCCEEEECCCCCEEEECCCCEEEEEECCCEE
RVWFEAGKKIDYYVIFGDSIDDVIKGYRKLTGDAPLLPKWAYGYWQSKERYKSQDELVSV
EEEEECCCEEEEEEEECCCHHHHHHHHHHHCCCCCCCCCHHCCCCCCHHHHCCHHHHHHH
VKEFRERKIPLDVIVLDWRYWGKYGWNAFKFDEIDFPRPKDMVEEIHKMGAKLAISIWPT
HHHHHHCCCCEEEEEEEEEECCCCCCCEEEECCCCCCCCHHHHHHHHHCCCEEEEEEECC
FGKETEVFKNMESKGCIIPGTTAVNPFKEGCRELFWSYVKRFYDIGIDAYWLDASEPETG
CCCHHHHHHCCCCCCCEECCCCCCCHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCC
LGLVFFSPIHDVDLGIGKGYEHLNAYPLMETKAVYEGQRRISDKRVAILTRSAFAGQQRY
EEEEEECCCCCCCCCCCCCHHHCCCCCCCHHHHHHHHHHHCCCCEEEEEEECHHCCCHHC
SAISWSGDVLGDWATLRSQIPAGLNFSISGIPYWTTDTGGFFSGNPETKAYAEIFVRWFQ
EEEECCCCCCCCHHHHHHHCCCCCCEEECCCEEEECCCCCCCCCCCCCHHHHHHHHHHHH
WSTFCPILRVHGTIFPKEPWRFPKEYQDVILKYIRLRYELLPYIYSLAWMTYSNGYTIMR
HCCCCCEEECCCEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCEEEE
PLVMDFRNDKNVYDLDEQYMFGPYIMVSPVTLPSIREKEVYLPSDEYWYDFWTGEKLKGG
EHHHHHCCCCCEEECCCCEEECCEEEECCCCCCCCCCCEEECCCCCCEEEEECCCCCCCC
RTTNVKVSLGTIPLFVRGGAVLPLLGKDVSNAMEDWDVLHLRIYPGKDGYFEIYDDDGVT
CCEEEEEEECCEEEEEECCEEEEECCCHHHHHHCCCEEEEEEEEECCCCEEEEECCCCCE
YDYERGKYFIVPIRWDDNKQELTIGKKRGDLEMRKRIMITWVEKGKGIEYSKPDVEVEYD
EEECCCEEEEEEEEECCCCCEEEEECCCCCHHHCCEEEEEEEECCCCCCCCCCCEEEEEC
GKESITVKRH
CCCCEEEECC
>Mature Secondary Structure
MRIRNFNVEIEFIADNIVRVLYYYGREAIIDNSLVVLPNLEKLSIKGESTSPSIISLSSK
CEEEEEEEEEEEEHHHHHHHHHHHCCCEEECCCEEEEECCEEEEEECCCCCCCEEEECCC
SLSVDINTSNGELIIKDNKGGIVVKEKRRNLKFNEELSTYNVEQEFGLSEGERLYGLGQH
EEEEEEECCCCEEEEEECCCCEEEECCCCCCCCCCCCCEECCHHHCCCCCCCEEEEECCC
AGGNGLGQSSAYKLDYNGLSITLSQRNTDIGIPFMISSKGYGILWDNYSLGSISLKGNEL
CCCCCCCCCCEEEEECCCEEEEEECCCCCCCCEEEECCCCCEEEECCCCEEEEEECCCEE
RVWFEAGKKIDYYVIFGDSIDDVIKGYRKLTGDAPLLPKWAYGYWQSKERYKSQDELVSV
EEEEECCCEEEEEEEECCCHHHHHHHHHHHCCCCCCCCCHHCCCCCCHHHHCCHHHHHHH
VKEFRERKIPLDVIVLDWRYWGKYGWNAFKFDEIDFPRPKDMVEEIHKMGAKLAISIWPT
HHHHHHCCCCEEEEEEEEEECCCCCCCEEEECCCCCCCCHHHHHHHHHCCCEEEEEEECC
FGKETEVFKNMESKGCIIPGTTAVNPFKEGCRELFWSYVKRFYDIGIDAYWLDASEPETG
CCCHHHHHHCCCCCCCEECCCCCCCHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCC
LGLVFFSPIHDVDLGIGKGYEHLNAYPLMETKAVYEGQRRISDKRVAILTRSAFAGQQRY
EEEEEECCCCCCCCCCCCCHHHCCCCCCCHHHHHHHHHHHCCCCEEEEEEECHHCCCHHC
SAISWSGDVLGDWATLRSQIPAGLNFSISGIPYWTTDTGGFFSGNPETKAYAEIFVRWFQ
EEEECCCCCCCCHHHHHHHCCCCCCEEECCCEEEECCCCCCCCCCCCCHHHHHHHHHHHH
WSTFCPILRVHGTIFPKEPWRFPKEYQDVILKYIRLRYELLPYIYSLAWMTYSNGYTIMR
HCCCCCEEECCCEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCEEEE
PLVMDFRNDKNVYDLDEQYMFGPYIMVSPVTLPSIREKEVYLPSDEYWYDFWTGEKLKGG
EHHHHHCCCCCEEECCCCEEECCEEEECCCCCCCCCCCEEECCCCCCEEEEECCCCCCCC
RTTNVKVSLGTIPLFVRGGAVLPLLGKDVSNAMEDWDVLHLRIYPGKDGYFEIYDDDGVT
CCEEEEEEECCEEEEEECCEEEEECCCHHHHHHCCCEEEEEEEEECCCCEEEEECCCCCE
YDYERGKYFIVPIRWDDNKQELTIGKKRGDLEMRKRIMITWVEKGKGIEYSKPDVEVEYD
EEECCCEEEEEEEEECCCCCEEEEECCCCCHHHCCEEEEEEEECCCCCCCCCCCEEEEEC
GKESITVKRH
CCCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10801892; 11427726 [H]