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The map label for this gene is dapA [H]

Identifier: 227828569

GI number: 227828569

Start: 2136164

End: 2137066

Strand: Direct

Name: dapA [H]

Synonym: M1425_2321

Alternate gene names: 227828569

Gene position: 2136164-2137066 (Clockwise)

Preceding gene: 227828568

Following gene: 227828570

Centisome position: 81.88

GC content: 33.11

Gene sequence:

>903_bases
ATGGAAGGAGTTTTCCTAACTAATATAACTCCTTTTACTAAAACTTTAGACCTAGATTTGGATGGGTTAAGAAAAATTAT
CCAATTTGCGGAAGGTATAGGCTATAAATACATAGTCCCTTTAGGTACAGCTGGAGAGTTCTCTTCACTTACATTTCAAG
AGAAAGTATTAGTAGTTGATACTGTAAGAAAAACGTTAAATAAAGGTGAAATAATAGCAGGAGCTTCATCCACATCGTTC
TTAGAAACTGGAGAACTTTGTAAAAAATATAAAGAAATGGGAATCAATACGATAATGATAACCCCACCCTATTATCTTAA
AGGAAGCGAAAAGGGTCTCTTAGATTATTTTACAAAGGTAAGCCAACTCTGTGACTTTGATGCAATAGTGATCTACAATA
ACCCCTCAACTGTGGGAATAGACCTTTCACCCCAATTATTGAAGACATTAAGTGAATCAATATCTAATTTCAAGGCATTA
AAAGAGGCTAGATATAATGTAGTCGAATTTAAGGAAGTTGAGAGATTAATAGGAGATAGAATCGACGTTATAGACGGATT
AGAGGAAAGAGCGTTATTAGGACTTATATTAGGAGCTAAGGGTTTCACTACGTCAATGGGATCCTTTTCAGCATTACCTC
TTAAAATTTTTGAAAATTATAAGAAATATGATATCGAGAATGCTACAAAACTATACGATCTATTATTAGAGTATAGATCC
TTCATAAAATTCCCGCTAACTATGTCACATTTATCAAAGTTAGGTGCTTGGTTAAGGGGATTGATATCGAGTTATGTTAC
AAGACCCCCATTATCAAACCTAGATGATATAGTAAATGATAATACAAAAAGGAAGATGATAGAGGTAATCAAGAACAGAA
TATTTAGGATTGAAACTGCATAA

Upstream 100 bases:

>100_bases
CTCTCAAACTTAACTCTGGATAAGCAAGACTGCTAAATACTATTTTCATATTTACAAGTTTACTCAAATCTTTAAAATTG
TTTGCTGTTTAGTTAATGTC

Downstream 100 bases:

>100_bases
CATATATATGTTAACCAATTATTATAAAAGAAAAAGATTTTTGAACTAGAATCAATTAAGTATAAGAATACTATATAACA
AATAGGATATCGACTATAGA

Product: dihydrodipicolinate synthetase

Products: NA

Alternate protein names: DHDPS [H]

Number of amino acids: Translated: 300; Mature: 300

Protein sequence:

>300_residues
MEGVFLTNITPFTKTLDLDLDGLRKIIQFAEGIGYKYIVPLGTAGEFSSLTFQEKVLVVDTVRKTLNKGEIIAGASSTSF
LETGELCKKYKEMGINTIMITPPYYLKGSEKGLLDYFTKVSQLCDFDAIVIYNNPSTVGIDLSPQLLKTLSESISNFKAL
KEARYNVVEFKEVERLIGDRIDVIDGLEERALLGLILGAKGFTTSMGSFSALPLKIFENYKKYDIENATKLYDLLLEYRS
FIKFPLTMSHLSKLGAWLRGLISSYVTRPPLSNLDDIVNDNTKRKMIEVIKNRIFRIETA

Sequences:

>Translated_300_residues
MEGVFLTNITPFTKTLDLDLDGLRKIIQFAEGIGYKYIVPLGTAGEFSSLTFQEKVLVVDTVRKTLNKGEIIAGASSTSF
LETGELCKKYKEMGINTIMITPPYYLKGSEKGLLDYFTKVSQLCDFDAIVIYNNPSTVGIDLSPQLLKTLSESISNFKAL
KEARYNVVEFKEVERLIGDRIDVIDGLEERALLGLILGAKGFTTSMGSFSALPLKIFENYKKYDIENATKLYDLLLEYRS
FIKFPLTMSHLSKLGAWLRGLISSYVTRPPLSNLDDIVNDNTKRKMIEVIKNRIFRIETA
>Mature_300_residues
MEGVFLTNITPFTKTLDLDLDGLRKIIQFAEGIGYKYIVPLGTAGEFSSLTFQEKVLVVDTVRKTLNKGEIIAGASSTSF
LETGELCKKYKEMGINTIMITPPYYLKGSEKGLLDYFTKVSQLCDFDAIVIYNNPSTVGIDLSPQLLKTLSESISNFKAL
KEARYNVVEFKEVERLIGDRIDVIDGLEERALLGLILGAKGFTTSMGSFSALPLKIFENYKKYDIENATKLYDLLLEYRS
FIKFPLTMSHLSKLGAWLRGLISSYVTRPPLSNLDDIVNDNTKRKMIEVIKNRIFRIETA

Specific function: Unknown

COG id: COG0329

COG function: function code EM; Dihydrodipicolinate synthase/N-acetylneuraminate lyase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DHDPS family [H]

Homologues:

Organism=Homo sapiens, GI31543060, Length=263, Percent_Identity=25.0950570342205, Blast_Score=74, Evalue=1e-13,
Organism=Escherichia coli, GI1786463, Length=288, Percent_Identity=26.0416666666667, Blast_Score=93, Evalue=2e-20,
Organism=Escherichia coli, GI1788823, Length=213, Percent_Identity=27.2300469483568, Blast_Score=88, Evalue=6e-19,
Organism=Escherichia coli, GI87082415, Length=265, Percent_Identity=23.7735849056604, Blast_Score=75, Evalue=5e-15,
Organism=Escherichia coli, GI1789620, Length=288, Percent_Identity=24.6527777777778, Blast_Score=69, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR005263
- InterPro:   IPR002220
- InterPro:   IPR020625
- InterPro:   IPR020624 [H]

Pfam domain/function: PF00701 DHDPS [H]

EC number: =4.2.1.52 [H]

Molecular weight: Translated: 33768; Mature: 33768

Theoretical pI: Translated: 8.12; Mature: 8.12

Prosite motif: PS00666 DHDPS_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEGVFLTNITPFTKTLDLDLDGLRKIIQFAEGIGYKYIVPLGTAGEFSSLTFQEKVLVVD
CCCEEECCCCCCHHEECCCHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCHHHHHHHHHH
TVRKTLNKGEIIAGASSTSFLETGELCKKYKEMGINTIMITPPYYLKGSEKGLLDYFTKV
HHHHHHCCCCEEECCCCCHHHHHHHHHHHHHHCCCCEEEECCCCEECCCCCHHHHHHHHH
SQLCDFDAIVIYNNPSTVGIDLSPQLLKTLSESISNFKALKEARYNVVEFKEVERLIGDR
HHHCCCCEEEEECCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCH
IDVIDGLEERALLGLILGAKGFTTSMGSFSALPLKIFENYKKYDIENATKLYDLLLEYRS
HHHHCCHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHH
FIKFPLTMSHLSKLGAWLRGLISSYVTRPPLSNLDDIVNDNTKRKMIEVIKNRIFRIETA
HHCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHCCCHHHHHHHHHHHHHEEEECC
>Mature Secondary Structure
MEGVFLTNITPFTKTLDLDLDGLRKIIQFAEGIGYKYIVPLGTAGEFSSLTFQEKVLVVD
CCCEEECCCCCCHHEECCCHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCHHHHHHHHHH
TVRKTLNKGEIIAGASSTSFLETGELCKKYKEMGINTIMITPPYYLKGSEKGLLDYFTKV
HHHHHHCCCCEEECCCCCHHHHHHHHHHHHHHCCCCEEEECCCCEECCCCCHHHHHHHHH
SQLCDFDAIVIYNNPSTVGIDLSPQLLKTLSESISNFKALKEARYNVVEFKEVERLIGDR
HHHCCCCEEEEECCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCH
IDVIDGLEERALLGLILGAKGFTTSMGSFSALPLKIFENYKKYDIENATKLYDLLLEYRS
HHHHCCHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHH
FIKFPLTMSHLSKLGAWLRGLISSYVTRPPLSNLDDIVNDNTKRKMIEVIKNRIFRIETA
HHCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHCCCHHHHHHHHHHHHHEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11930014 [H]