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The map label for this gene is ygcS [H]

Identifier: 227828495

GI number: 227828495

Start: 2054356

End: 2055771

Strand: Direct

Name: ygcS [H]

Synonym: M1425_2244

Alternate gene names: 227828495

Gene position: 2054356-2055771 (Clockwise)

Preceding gene: 227828493

Following gene: 227828497

Centisome position: 78.75

GC content: 37.29

Gene sequence:

>1416_bases
ATGTCGCAATACTCTAAAGAAGAAATAGATAGGGGTATCAAAAAGATATATGATACGGTTTTGAATACAAAAAATATAAC
CTCAAGATATATAGTAATTTTAGCATTAGCTAGTCTCTGGCTAGATGCCTATGACTTTGCAAGTATGACTTTTGGTACTG
CATCCCTTAAGAGCACTTTCCCTTCTGTACCATCTGTTTTAATTTCCTTGGCTATAGGTGCAGTACAATTAGGTGCTATT
ATAGGTGCAGTGGTTGGCGGTTGGCTAAACGATCGTATTGGTAGGAGGAACATGTTCATACTTAACATGATATTATTTAC
GGGTATGGCAATCTTGGGAGGATTATCTACTAACATTACAGAATTATCAATCTTCAGAGGCTTATTAGGTTTCGCTTTAG
GGGCTGATACTGCAACAGGTTTTGCTTATATATTCGAGTATTTAGAGAAAAAACAGAGACTATTTTGGTCGAATCTATGG
CAAATACAATGGTATATCATGTACGAGGTTACCATAGCTTTAATAGTAGTTCCATTCTTCTTTACAGTTCACTCATTGAC
ATCTCCCTTATTATGGAGAATTATTATGATAGTTGGAGGTGTTCTAGCTTTAGTAATATTACTACTAAGAGGTAGGATTC
CCGAATCGGTATTATGGTTAGCATACCAAGGTAAATTAGCTACTGCCAAGAAAATATTGAAACAGACCTACGGAATAGAT
TTGCCAGATGTCCCAGACGTGGATTTGCAACTAAGGGCACCAGCTAGAGGAGTAAGGAGTGCCTTTAGTATATTTAGAGC
GAGTAAATGGAGGGAGCTGGTCTATTCCTTTAACGGTAACTTTGAACAAGGATTCATATTCTATACATTTGGTTTTTATG
TTCCTTATATATTACTAGCGCTAAAACTGGCTGGGCCACTTGCCTCAATAGTAGCTTCTGCATTCCTATATGCCGGAGGC
GTAATAGGTGGCTATTTGACAGCATGGCTAACACCTAAAATTGGCACTAAATCACAATATGTAATAGGAGCAATAGGGGA
GGGAATTTCAGTAGGGTTAATTGCACTTACATACATTTATCGCTTACCATTAATATATTTTGTAGTGTTCTCTTTCCTAT
TTTACTTCTTCCATGTCATAGGTCCAGCCAGTCAAGGGATGACATCCATAAATGCATTTTTTGGAGCCAAAGAAAGAGGT
ACTGCTGCGGGATGGGGATATTTCTGGGTAAAATTGGCTGCTTTTATAGGATTGCTAATAGGAATTGTTGGCATAACTTA
CAATCCAGTAGATCTAACGTTAGGTTTGGCAGTTTACGGTATCTTAACTGGTATAGTAGGCTTAATTATAGGTTATGATA
CTAGGACATATAAGGTAGCAGACGTGGAAGAATTAGAAGAAAAAACAGTTGAATAA

Upstream 100 bases:

>100_bases
GCTATGTTTCTACAAAAATAAAGGATAGTAAGAATCTTTACTAGTAAAGTTATCTATTTAAATATTTCCTTAATGATATG
ATTATTCTGATGGAGAGAGT

Downstream 100 bases:

>100_bases
ACATAATACCAAAAGATTTTTAAAAAACTGTATTATCTTTTTTCTTTCTTTATAACTGGAGTTATTAAGGTTCCTATATT
GCTTATACTTATCTCCACTA

Product: major facilitator superfamily MFS_1

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 471; Mature: 470

Protein sequence:

>471_residues
MSQYSKEEIDRGIKKIYDTVLNTKNITSRYIVILALASLWLDAYDFASMTFGTASLKSTFPSVPSVLISLAIGAVQLGAI
IGAVVGGWLNDRIGRRNMFILNMILFTGMAILGGLSTNITELSIFRGLLGFALGADTATGFAYIFEYLEKKQRLFWSNLW
QIQWYIMYEVTIALIVVPFFFTVHSLTSPLLWRIIMIVGGVLALVILLLRGRIPESVLWLAYQGKLATAKKILKQTYGID
LPDVPDVDLQLRAPARGVRSAFSIFRASKWRELVYSFNGNFEQGFIFYTFGFYVPYILLALKLAGPLASIVASAFLYAGG
VIGGYLTAWLTPKIGTKSQYVIGAIGEGISVGLIALTYIYRLPLIYFVVFSFLFYFFHVIGPASQGMTSINAFFGAKERG
TAAGWGYFWVKLAAFIGLLIGIVGITYNPVDLTLGLAVYGILTGIVGLIIGYDTRTYKVADVEELEEKTVE

Sequences:

>Translated_471_residues
MSQYSKEEIDRGIKKIYDTVLNTKNITSRYIVILALASLWLDAYDFASMTFGTASLKSTFPSVPSVLISLAIGAVQLGAI
IGAVVGGWLNDRIGRRNMFILNMILFTGMAILGGLSTNITELSIFRGLLGFALGADTATGFAYIFEYLEKKQRLFWSNLW
QIQWYIMYEVTIALIVVPFFFTVHSLTSPLLWRIIMIVGGVLALVILLLRGRIPESVLWLAYQGKLATAKKILKQTYGID
LPDVPDVDLQLRAPARGVRSAFSIFRASKWRELVYSFNGNFEQGFIFYTFGFYVPYILLALKLAGPLASIVASAFLYAGG
VIGGYLTAWLTPKIGTKSQYVIGAIGEGISVGLIALTYIYRLPLIYFVVFSFLFYFFHVIGPASQGMTSINAFFGAKERG
TAAGWGYFWVKLAAFIGLLIGIVGITYNPVDLTLGLAVYGILTGIVGLIIGYDTRTYKVADVEELEEKTVE
>Mature_470_residues
SQYSKEEIDRGIKKIYDTVLNTKNITSRYIVILALASLWLDAYDFASMTFGTASLKSTFPSVPSVLISLAIGAVQLGAII
GAVVGGWLNDRIGRRNMFILNMILFTGMAILGGLSTNITELSIFRGLLGFALGADTATGFAYIFEYLEKKQRLFWSNLWQ
IQWYIMYEVTIALIVVPFFFTVHSLTSPLLWRIIMIVGGVLALVILLLRGRIPESVLWLAYQGKLATAKKILKQTYGIDL
PDVPDVDLQLRAPARGVRSAFSIFRASKWRELVYSFNGNFEQGFIFYTFGFYVPYILLALKLAGPLASIVASAFLYAGGV
IGGYLTAWLTPKIGTKSQYVIGAIGEGISVGLIALTYIYRLPLIYFVVFSFLFYFFHVIGPASQGMTSINAFFGAKERGT
AAGWGYFWVKLAAFIGLLIGIVGITYNPVDLTLGLAVYGILTGIVGLIIGYDTRTYKVADVEELEEKTVE

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family [H]

Homologues:

Organism=Escherichia coli, GI87082159, Length=250, Percent_Identity=29.2, Blast_Score=76, Evalue=5e-15,
Organism=Escherichia coli, GI1786229, Length=340, Percent_Identity=25.2941176470588, Blast_Score=73, Evalue=4e-14,
Organism=Escherichia coli, GI1788074, Length=181, Percent_Identity=29.8342541436464, Blast_Score=71, Evalue=2e-13,
Organism=Escherichia coli, GI1788068, Length=327, Percent_Identity=24.1590214067278, Blast_Score=66, Evalue=4e-12,
Organism=Drosophila melanogaster, GI221330907, Length=250, Percent_Identity=25.6, Blast_Score=65, Evalue=9e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020846
- InterPro:   IPR016196
- InterPro:   IPR005828
- InterPro:   IPR005829 [H]

Pfam domain/function: PF00083 Sugar_tr [H]

EC number: NA

Molecular weight: Translated: 52029; Mature: 51898

Theoretical pI: Translated: 9.58; Mature: 9.58

Prosite motif: PS50850 MFS ; PS00217 SUGAR_TRANSPORT_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSQYSKEEIDRGIKKIYDTVLNTKNITSRYIVILALASLWLDAYDFASMTFGTASLKSTF
CCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHC
PSVPSVLISLAIGAVQLGAIIGAVVGGWLNDRIGRRNMFILNMILFTGMAILGGLSTNIT
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCHH
ELSIFRGLLGFALGADTATGFAYIFEYLEKKQRLFWSNLWQIQWYIMYEVTIALIVVPFF
HHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FTVHSLTSPLLWRIIMIVGGVLALVILLLRGRIPESVLWLAYQGKLATAKKILKQTYGID
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHEEEEECCCHHHHHHHHHHHHCCC
LPDVPDVDLQLRAPARGVRSAFSIFRASKWRELVYSFNGNFEQGFIFYTFGFYVPYILLA
CCCCCCCCEEECCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEHHHHHHHHHHH
LKLAGPLASIVASAFLYAGGVIGGYLTAWLTPKIGTKSQYVIGAIGEGISVGLIALTYIY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEECCCCHHHHHHHHHHHH
RLPLIYFVVFSFLFYFFHVIGPASQGMTSINAFFGAKERGTAAGWGYFWVKLAAFIGLLI
HHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHH
GIVGITYNPVDLTLGLAVYGILTGIVGLIIGYDTRTYKVADVEELEEKTVE
HHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCHHHHHHHCCC
>Mature Secondary Structure 
SQYSKEEIDRGIKKIYDTVLNTKNITSRYIVILALASLWLDAYDFASMTFGTASLKSTF
CCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHC
PSVPSVLISLAIGAVQLGAIIGAVVGGWLNDRIGRRNMFILNMILFTGMAILGGLSTNIT
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCHH
ELSIFRGLLGFALGADTATGFAYIFEYLEKKQRLFWSNLWQIQWYIMYEVTIALIVVPFF
HHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FTVHSLTSPLLWRIIMIVGGVLALVILLLRGRIPESVLWLAYQGKLATAKKILKQTYGID
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHEEEEECCCHHHHHHHHHHHHCCC
LPDVPDVDLQLRAPARGVRSAFSIFRASKWRELVYSFNGNFEQGFIFYTFGFYVPYILLA
CCCCCCCCEEECCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEHHHHHHHHHHH
LKLAGPLASIVASAFLYAGGVIGGYLTAWLTPKIGTKSQYVIGAIGEGISVGLIALTYIY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEECCCCHHHHHHHHHHHH
RLPLIYFVVFSFLFYFFHVIGPASQGMTSINAFFGAKERGTAAGWGYFWVKLAAFIGLLI
HHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHH
GIVGITYNPVDLTLGLAVYGILTGIVGLIIGYDTRTYKVADVEELEEKTVE
HHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]