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The map label for this gene is yaaU [H]

Identifier: 227828435

GI number: 227828435

Start: 2001697

End: 2003112

Strand: Direct

Name: yaaU [H]

Synonym: M1425_2181

Alternate gene names: 227828435

Gene position: 2001697-2003112 (Clockwise)

Preceding gene: 227828434

Following gene: 227828436

Centisome position: 76.73

GC content: 37.01

Gene sequence:

>1416_bases
ATGGATAAAGGAATTTCAAAAACGCCTTTTGCTTCTATTGATTCACTGAAGCTAACTTTCAACCATATTAAAGTTTGGTA
CACTTCTGGTATGGGATTTTTTACTGATGCTTATGATTTGTTCATAATAAGTGCAATTCTGGACGTTTTAATACAGTTGC
ATGATCCTAATTTTCCACTAAATAGTTTTACAGAGGGTCTTTTAGCGTCATCTGCGTTATGGACGGCAATAATTGGGCAA
TTAGTCTTTGGTTTCTTAGGTGATAAGATAGGAAGGAAGGCAATATATGGGATTGAAGCAATGTTGATGGCGGTTGGTGC
TTTACTTTCTGCGATCTCTCCAAATATATACTGGCTAATAATTTTTAGGTCAATTATGGGTTTGGGAATAGGTGGAGATT
ACCCAATTTCCGCTACTATAATGAGTGAGTATGCTAATGTTAAAGATAGGGGTAAGTTGATAGCTTTAGTGTTTGCAAAT
CAAGGATTAGGTAGTTTAGCTGCAGTTGCAATAGGGATTGGTAGTGTTTTAGCGTTTCCCTTAGATATTTCTTGGAGAAT
AATGGCAGCCATAGGTGCAATACCAGCTGCTACTGTAATATATCTTAGAAGAAAAACTCCAGAAACTCCTAGATATTCAA
TGTTAGTGAAGGGTAGCGTACAAGAGGCTAAGAAAGCTGCCGAGTTCCTAGGTGCTAGAATTGAGGAAAAGAAAGTTAAC
TCAAAGCCGATTTCTTTGTCACAGTTCCTATCTAAGTACTGGCTAACACTCATAGGTACTGCAGTTCCATGGTTTATCCT
TGATATAGCGTTTTATGGAACTGGAATATACTCTGGTGCAATAACTCAATTAATATTAGGGAAACCCAGTAGTATAGCAA
ATTTAATATTAGAACAAGGTTTGCCATACATGGTAGGATTCTTCGGTTACTTTACGGCAGTTGCATTGATGGATAAGTTA
GGAAGAAAAATTATACAGTTACAAGGCTTTATATTAATGGGTATAATTTATGCAGCTGTTTCCTCATTCTTAATAGTTAG
TGGAACTAAGGTAATTGGTTTAACGATTCCAGCTGAACTTGGATTCTTGATATACGCACTATCATTCTTCTTCATAGACT
TTGGTCCTAATACTACAACCTTTGTACTCCCTGCTGAAACTTACCCAACTAGGGCTAGGACTACTGGCCATGGGATTAGT
GCAGCATCAGGTAAATTGGGGGCTGCAATAACTACTTACCTATTCCCTACGCTTTTGGCCTCGATAGGAATAAAGAATAT
TTTATTAATGCTTTCAGTGCTATCAATACTAGGCGCGATAGTAACTATAATAGCTGTTAAGGAAACTAAAGGTAAGAGTT
TAGAGGAAGTAAGTGAAGAAGAGGTAATTGTTCAAGAAGAAAAAGCCTCTGCATAA

Upstream 100 bases:

>100_bases
CAAAAAAGGGGACTATATAAATTATATAGTTGACAATAGATTATATTTACTTTATAGGTAAAATATATAATAGTCGAAGC
TGAGATAGGCATGAGAAAAA

Downstream 100 bases:

>100_bases
ATTAACTATATGTAAAAAGTCTTTTTAAATGACATCATTTTAGTTAGTGGTACTTTCTTTTCTCTTTTAATACGTAAATT
TTACGTTTTATTTTTTTTTT

Product: general substrate transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 471; Mature: 471

Protein sequence:

>471_residues
MDKGISKTPFASIDSLKLTFNHIKVWYTSGMGFFTDAYDLFIISAILDVLIQLHDPNFPLNSFTEGLLASSALWTAIIGQ
LVFGFLGDKIGRKAIYGIEAMLMAVGALLSAISPNIYWLIIFRSIMGLGIGGDYPISATIMSEYANVKDRGKLIALVFAN
QGLGSLAAVAIGIGSVLAFPLDISWRIMAAIGAIPAATVIYLRRKTPETPRYSMLVKGSVQEAKKAAEFLGARIEEKKVN
SKPISLSQFLSKYWLTLIGTAVPWFILDIAFYGTGIYSGAITQLILGKPSSIANLILEQGLPYMVGFFGYFTAVALMDKL
GRKIIQLQGFILMGIIYAAVSSFLIVSGTKVIGLTIPAELGFLIYALSFFFIDFGPNTTTFVLPAETYPTRARTTGHGIS
AASGKLGAAITTYLFPTLLASIGIKNILLMLSVLSILGAIVTIIAVKETKGKSLEEVSEEEVIVQEEKASA

Sequences:

>Translated_471_residues
MDKGISKTPFASIDSLKLTFNHIKVWYTSGMGFFTDAYDLFIISAILDVLIQLHDPNFPLNSFTEGLLASSALWTAIIGQ
LVFGFLGDKIGRKAIYGIEAMLMAVGALLSAISPNIYWLIIFRSIMGLGIGGDYPISATIMSEYANVKDRGKLIALVFAN
QGLGSLAAVAIGIGSVLAFPLDISWRIMAAIGAIPAATVIYLRRKTPETPRYSMLVKGSVQEAKKAAEFLGARIEEKKVN
SKPISLSQFLSKYWLTLIGTAVPWFILDIAFYGTGIYSGAITQLILGKPSSIANLILEQGLPYMVGFFGYFTAVALMDKL
GRKIIQLQGFILMGIIYAAVSSFLIVSGTKVIGLTIPAELGFLIYALSFFFIDFGPNTTTFVLPAETYPTRARTTGHGIS
AASGKLGAAITTYLFPTLLASIGIKNILLMLSVLSILGAIVTIIAVKETKGKSLEEVSEEEVIVQEEKASA
>Mature_471_residues
MDKGISKTPFASIDSLKLTFNHIKVWYTSGMGFFTDAYDLFIISAILDVLIQLHDPNFPLNSFTEGLLASSALWTAIIGQ
LVFGFLGDKIGRKAIYGIEAMLMAVGALLSAISPNIYWLIIFRSIMGLGIGGDYPISATIMSEYANVKDRGKLIALVFAN
QGLGSLAAVAIGIGSVLAFPLDISWRIMAAIGAIPAATVIYLRRKTPETPRYSMLVKGSVQEAKKAAEFLGARIEEKKVN
SKPISLSQFLSKYWLTLIGTAVPWFILDIAFYGTGIYSGAITQLILGKPSSIANLILEQGLPYMVGFFGYFTAVALMDKL
GRKIIQLQGFILMGIIYAAVSSFLIVSGTKVIGLTIPAELGFLIYALSFFFIDFGPNTTTFVLPAETYPTRARTTGHGIS
AASGKLGAAITTYLFPTLLASIGIKNILLMLSVLSILGAIVTIIAVKETKGKSLEEVSEEEVIVQEEKASA

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family [H]

Homologues:

Organism=Homo sapiens, GI24308167, Length=476, Percent_Identity=25.6302521008403, Blast_Score=98, Evalue=1e-20,
Organism=Homo sapiens, GI213021148, Length=468, Percent_Identity=24.3589743589744, Blast_Score=84, Evalue=3e-16,
Organism=Homo sapiens, GI166064021, Length=404, Percent_Identity=23.019801980198, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI302148518, Length=432, Percent_Identity=25.462962962963, Blast_Score=75, Evalue=2e-13,
Organism=Homo sapiens, GI21361449, Length=331, Percent_Identity=24.773413897281, Blast_Score=67, Evalue=5e-11,
Organism=Homo sapiens, GI4506999, Length=398, Percent_Identity=24.1206030150754, Blast_Score=66, Evalue=7e-11,
Organism=Escherichia coli, GI1786229, Length=468, Percent_Identity=24.3589743589744, Blast_Score=134, Evalue=1e-32,
Organism=Escherichia coli, GI87082159, Length=458, Percent_Identity=28.3842794759825, Blast_Score=116, Evalue=3e-27,
Organism=Escherichia coli, GI1788068, Length=421, Percent_Identity=27.3159144893112, Blast_Score=103, Evalue=2e-23,
Organism=Escherichia coli, GI1788074, Length=443, Percent_Identity=26.86230248307, Blast_Score=88, Evalue=1e-18,
Organism=Escherichia coli, GI1789312, Length=427, Percent_Identity=26.463700234192, Blast_Score=85, Evalue=8e-18,
Organism=Escherichia coli, GI1789207, Length=436, Percent_Identity=26.1467889908257, Blast_Score=81, Evalue=1e-16,
Organism=Escherichia coli, GI1790550, Length=415, Percent_Identity=25.3012048192771, Blast_Score=72, Evalue=8e-14,
Organism=Escherichia coli, GI1790463, Length=457, Percent_Identity=25.382932166302, Blast_Score=69, Evalue=7e-13,
Organism=Escherichia coli, GI87082404, Length=189, Percent_Identity=26.4550264550265, Blast_Score=68, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI32564663, Length=477, Percent_Identity=21.1740041928721, Blast_Score=69, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI17565976, Length=358, Percent_Identity=24.5810055865922, Blast_Score=67, Evalue=3e-11,
Organism=Saccharomyces cerevisiae, GI6323512, Length=525, Percent_Identity=33.3333333333333, Blast_Score=228, Evalue=2e-60,
Organism=Saccharomyces cerevisiae, GI6319941, Length=393, Percent_Identity=24.6819338422392, Blast_Score=93, Evalue=1e-19,
Organism=Saccharomyces cerevisiae, GI6320705, Length=491, Percent_Identity=23.8289205702648, Blast_Score=68, Evalue=3e-12,
Organism=Saccharomyces cerevisiae, GI6323653, Length=442, Percent_Identity=24.2081447963801, Blast_Score=66, Evalue=1e-11,
Organism=Saccharomyces cerevisiae, GI6320766, Length=466, Percent_Identity=23.6051502145923, Blast_Score=65, Evalue=3e-11,
Organism=Saccharomyces cerevisiae, GI6324469, Length=487, Percent_Identity=23.2032854209446, Blast_Score=64, Evalue=6e-11,
Organism=Drosophila melanogaster, GI24652793, Length=457, Percent_Identity=24.0700218818381, Blast_Score=73, Evalue=4e-13,
Organism=Drosophila melanogaster, GI24654932, Length=398, Percent_Identity=23.8693467336683, Blast_Score=73, Evalue=5e-13,
Organism=Drosophila melanogaster, GI17737517, Length=398, Percent_Identity=23.8693467336683, Blast_Score=73, Evalue=5e-13,
Organism=Drosophila melanogaster, GI24652795, Length=429, Percent_Identity=24.4755244755245, Blast_Score=73, Evalue=5e-13,
Organism=Drosophila melanogaster, GI161080349, Length=398, Percent_Identity=23.8693467336683, Blast_Score=72, Evalue=6e-13,
Organism=Drosophila melanogaster, GI161080353, Length=398, Percent_Identity=23.8693467336683, Blast_Score=72, Evalue=1e-12,
Organism=Drosophila melanogaster, GI161080351, Length=405, Percent_Identity=23.4567901234568, Blast_Score=70, Evalue=5e-12,
Organism=Drosophila melanogaster, GI19922874, Length=468, Percent_Identity=20.9401709401709, Blast_Score=67, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020846
- InterPro:   IPR016196
- InterPro:   IPR005828 [H]

Pfam domain/function: PF00083 Sugar_tr [H]

EC number: NA

Molecular weight: Translated: 50713; Mature: 50713

Theoretical pI: Translated: 9.44; Mature: 9.44

Prosite motif: PS50850 MFS ; PS00216 SUGAR_TRANSPORT_1 ; PS00217 SUGAR_TRANSPORT_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDKGISKTPFASIDSLKLTFNHIKVWYTSGMGFFTDAYDLFIISAILDVLIQLHDPNFPL
CCCCCCCCCCCCCCCEEEEEEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCH
NSFTEGLLASSALWTAIIGQLVFGFLGDKIGRKAIYGIEAMLMAVGALLSAISPNIYWLI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHH
IFRSIMGLGIGGDYPISATIMSEYANVKDRGKLIALVFANQGLGSLAAVAIGIGSVLAFP
HHHHHHHCCCCCCCCCHHHHHHHHHCCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHC
LDISWRIMAAIGAIPAATVIYLRRKTPETPRYSMLVKGSVQEAKKAAEFLGARIEEKKVN
CCCHHHHHHHHHCCHHHHHHEEECCCCCCCCEEEEEECCHHHHHHHHHHHHCHHHHHHCC
SKPISLSQFLSKYWLTLIGTAVPWFILDIAFYGTGIYSGAITQLILGKPSSIANLILEQG
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHCCCHHHHHHHHHCC
LPYMVGFFGYFTAVALMDKLGRKIIQLQGFILMGIIYAAVSSFLIVSGTKVIGLTIPAEL
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECHHHH
GFLIYALSFFFIDFGPNTTTFVLPAETYPTRARTTGHGISAASGKLGAAITTYLFPTLLA
HHHHHHHHHHHEEECCCCEEEEEECCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHH
SIGIKNILLMLSVLSILGAIVTIIAVKETKGKSLEEVSEEEVIVQEEKASA
HHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCHHHHCHHHHEEECCCCCC
>Mature Secondary Structure
MDKGISKTPFASIDSLKLTFNHIKVWYTSGMGFFTDAYDLFIISAILDVLIQLHDPNFPL
CCCCCCCCCCCCCCCEEEEEEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCH
NSFTEGLLASSALWTAIIGQLVFGFLGDKIGRKAIYGIEAMLMAVGALLSAISPNIYWLI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHH
IFRSIMGLGIGGDYPISATIMSEYANVKDRGKLIALVFANQGLGSLAAVAIGIGSVLAFP
HHHHHHHCCCCCCCCCHHHHHHHHHCCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHC
LDISWRIMAAIGAIPAATVIYLRRKTPETPRYSMLVKGSVQEAKKAAEFLGARIEEKKVN
CCCHHHHHHHHHCCHHHHHHEEECCCCCCCCEEEEEECCHHHHHHHHHHHHCHHHHHHCC
SKPISLSQFLSKYWLTLIGTAVPWFILDIAFYGTGIYSGAITQLILGKPSSIANLILEQG
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHCCCHHHHHHHHHCC
LPYMVGFFGYFTAVALMDKLGRKIIQLQGFILMGIIYAAVSSFLIVSGTKVIGLTIPAEL
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECHHHH
GFLIYALSFFFIDFGPNTTTFVLPAETYPTRARTTGHGISAASGKLGAAITTYLFPTLLA
HHHHHHHHHHHEEECCCCEEEEEECCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHH
SIGIKNILLMLSVLSILGAIVTIIAVKETKGKSLEEVSEEEVIVQEEKASA
HHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCHHHHCHHHHEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1630901; 9278503 [H]