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The map label for this gene is iolC [H]

Identifier: 227828420

GI number: 227828420

Start: 1983794

End: 1984735

Strand: Direct

Name: iolC [H]

Synonym: M1425_2164

Alternate gene names: 227828420

Gene position: 1983794-1984735 (Clockwise)

Preceding gene: 227828419

Following gene: 227828421

Centisome position: 76.04

GC content: 37.47

Gene sequence:

>942_bases
ATGGTTGATGTAATAGCTTTAGGAGAGCCTTTAGTCCAATTTAATTCTTTTACCTCTGGTCCATTAAGATTCGTAAACTA
TTTTGAAAAACATATAGCAGGATCTGAGTTGAATTTCTGCATTGCCGTTATTAGAAATCATCTATCATGCGGTTTAATAG
CGAGAGTAGGTAATGACGAGTTTGGAAGAAATATCATAGAGTATTCCAGAGCTCAAGGTATTGATACTACCTATATAAAG
GTTGATAAGGAGTCTTTCACCGGGATATACTTTATACAGAGGGGTTATCCGATACCAATGAAAAGTGAACTAGTCTACTA
CAGAAGAGGCAGTGCAGGAAGTAGACTTTCTCCAGAAGACGTAGATGAAAAATACATTAAGAGTGCTAGGTTAATTCATT
CAACTGGGATAACATTGGCTATAAGCGACAGTGCTAAGGAGGCTATGATTAAAGCGTTTGAATTGGCAGAATCTAGGAGT
CTAGACACAAATATCAGACCTAAACTTTGGAGCAGCCTTGAAAAAGCTAGGGAAACAATCCTTTCAATATTAAAGAAATA
CGATATTGAGGTACTAATAACGGATCCAGATGACACTAAAATTTTGCTTGATGTTACGGATCCAGATGATGCATATAGGA
AATATAAAGAGTTAGGAGTCAAAGTCTTACTCTATAAATTAGGTGCTAAAGGTGCTATGGCATATAAAGACAGCGTAAAG
GCCTTTAAAGAAGGCTATAAAGTACAAGTTGAGGATCCTACTGGAGCTGGTGATGCAATGGCAGGGACATTTGTTTCGTT
GTATTTGCAGGGAAAGGATGTAGAATATTCGTTAGCTCATGGTATTGCGGCGTCAACTCTAGTTATAACAGTAAGGGGAG
ACAATGAACTTACGCCCACTACTGAGGATGCCGAAAGATTTTTAAATGAGTTTAAAACGTAA

Upstream 100 bases:

>100_bases
CCCATTAGATGAGGAAGAAGAGAGACAGTTAATTAAGAAAGTTGAGGGTATAAGGGCTAAACTTGTAGAGCTTAAAATAT
TGAAAGAATAGTATACTATC

Downstream 100 bases:

>100_bases
AGCCTAACATTTAAATTTTTCATTAATGATTATATATTATGGAGAAAACTTCATTGTTGATAAAATCTAAGGAGCTTACG
GGAATCTATGAACTAAAAGA

Product: PfkB domain protein

Products: NA

Alternate protein names: 2-deoxy-5-keto-D-gluconate kinase; DKG kinase [H]

Number of amino acids: Translated: 313; Mature: 313

Protein sequence:

>313_residues
MVDVIALGEPLVQFNSFTSGPLRFVNYFEKHIAGSELNFCIAVIRNHLSCGLIARVGNDEFGRNIIEYSRAQGIDTTYIK
VDKESFTGIYFIQRGYPIPMKSELVYYRRGSAGSRLSPEDVDEKYIKSARLIHSTGITLAISDSAKEAMIKAFELAESRS
LDTNIRPKLWSSLEKARETILSILKKYDIEVLITDPDDTKILLDVTDPDDAYRKYKELGVKVLLYKLGAKGAMAYKDSVK
AFKEGYKVQVEDPTGAGDAMAGTFVSLYLQGKDVEYSLAHGIAASTLVITVRGDNELTPTTEDAERFLNEFKT

Sequences:

>Translated_313_residues
MVDVIALGEPLVQFNSFTSGPLRFVNYFEKHIAGSELNFCIAVIRNHLSCGLIARVGNDEFGRNIIEYSRAQGIDTTYIK
VDKESFTGIYFIQRGYPIPMKSELVYYRRGSAGSRLSPEDVDEKYIKSARLIHSTGITLAISDSAKEAMIKAFELAESRS
LDTNIRPKLWSSLEKARETILSILKKYDIEVLITDPDDTKILLDVTDPDDAYRKYKELGVKVLLYKLGAKGAMAYKDSVK
AFKEGYKVQVEDPTGAGDAMAGTFVSLYLQGKDVEYSLAHGIAASTLVITVRGDNELTPTTEDAERFLNEFKT
>Mature_313_residues
MVDVIALGEPLVQFNSFTSGPLRFVNYFEKHIAGSELNFCIAVIRNHLSCGLIARVGNDEFGRNIIEYSRAQGIDTTYIK
VDKESFTGIYFIQRGYPIPMKSELVYYRRGSAGSRLSPEDVDEKYIKSARLIHSTGITLAISDSAKEAMIKAFELAESRS
LDTNIRPKLWSSLEKARETILSILKKYDIEVLITDPDDTKILLDVTDPDDAYRKYKELGVKVLLYKLGAKGAMAYKDSVK
AFKEGYKVQVEDPTGAGDAMAGTFVSLYLQGKDVEYSLAHGIAASTLVITVRGDNELTPTTEDAERFLNEFKT

Specific function: Catalyzes the phosphorylation of 5-dehydro-2-deoxy-D- gluconate (2-deoxy-5-keto-D-gluconate or DKG) to 6-phospho-5- dehydro-2-deoxy-D-gluconate (DKGP) [H]

COG id: COG0524

COG function: function code G; Sugar kinases, ribokinase family

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the carbohydrate kinase pfkB family [H]

Homologues:

Organism=Escherichia coli, GI87082281, Length=289, Percent_Identity=23.8754325259516, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI1790193, Length=307, Percent_Identity=23.7785016286645, Blast_Score=64, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011611
- InterPro:   IPR002173
- InterPro:   IPR022841 [H]

Pfam domain/function: PF00294 PfkB [H]

EC number: =2.7.1.92 [H]

Molecular weight: Translated: 34904; Mature: 34904

Theoretical pI: Translated: 5.52; Mature: 5.52

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVDVIALGEPLVQFNSFTSGPLRFVNYFEKHIAGSELNFCIAVIRNHLSCGLIARVGNDE
CEEEEECCCCHHHHCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCEEEEECCCCH
FGRNIIEYSRAQGIDTTYIKVDKESFTGIYFIQRGYPIPMKSELVYYRRGSAGSRLSPED
HHHHHHHHHHHCCCCEEEEEEECCCCCEEEEEECCCCCCCCCCEEEEECCCCCCCCCHHH
VDEKYIKSARLIHSTGITLAISDSAKEAMIKAFELAESRSLDTNIRPKLWSSLEKARETI
HHHHHHHHHHHEEECCCEEEECCCHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHH
LSILKKYDIEVLITDPDDTKILLDVTDPDDAYRKYKELGVKVLLYKLGAKGAMAYKDSVK
HHHHHHCCEEEEEECCCCCEEEEEECCCHHHHHHHHHHCCEEEEEECCCCCCHHHHHHHH
AFKEGYKVQVEDPTGAGDAMAGTFVSLYLQGKDVEYSLAHGIAASTLVITVRGDNELTPT
HHHCCCEEEEECCCCCCCHHHHEEEEEEEECCCCEEHHHCCCEEEEEEEEEECCCCCCCC
TEDAERFLNEFKT
HHHHHHHHHHHCC
>Mature Secondary Structure
MVDVIALGEPLVQFNSFTSGPLRFVNYFEKHIAGSELNFCIAVIRNHLSCGLIARVGNDE
CEEEEECCCCHHHHCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCEEEEECCCCH
FGRNIIEYSRAQGIDTTYIKVDKESFTGIYFIQRGYPIPMKSELVYYRRGSAGSRLSPED
HHHHHHHHHHHCCCCEEEEEEECCCCCEEEEEECCCCCCCCCCEEEEECCCCCCCCCHHH
VDEKYIKSARLIHSTGITLAISDSAKEAMIKAFELAESRSLDTNIRPKLWSSLEKARETI
HHHHHHHHHHHEEECCCEEEECCCHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHH
LSILKKYDIEVLITDPDDTKILLDVTDPDDAYRKYKELGVKVLLYKLGAKGAMAYKDSVK
HHHHHHCCEEEEEECCCCCEEEEEECCCHHHHHHHHHHCCEEEEEECCCCCCHHHHHHHH
AFKEGYKVQVEDPTGAGDAMAGTFVSLYLQGKDVEYSLAHGIAASTLVITVRGDNELTPT
HHHCCCEEEEECCCCCCCHHHHEEEEEEEECCCCEEHHHCCCEEEEEEEEEECCCCCCCC
TEDAERFLNEFKT
HHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11058132 [H]