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The map label for this gene is moaB [H]

Identifier: 227828352

GI number: 227828352

Start: 1916505

End: 1917041

Strand: Direct

Name: moaB [H]

Synonym: M1425_2094

Alternate gene names: 227828352

Gene position: 1916505-1917041 (Clockwise)

Preceding gene: 227828351

Following gene: 227828355

Centisome position: 73.46

GC content: 35.57

Gene sequence:

>537_bases
ATGTCATCACATAAACAACATAGGCAACATGCGCCTACTAATATAAATTTTTACGTAATTACAATTAGCACTTCTAGATA
TGAAAAGATGATGAAAAAAGAGCCAGTAATAGACGAGTCCGGCGATATTATAAAACAGCTAATTATACAATCGAATTATA
ATGTAGTAGGCTATGATTTGGTGCCAGATGAAAAGGTAAAGATACTTAAAGCATTTGCAAATGCCTTAGATAATTCCCAG
ACTGACGTAATTATATCAGCAGGGGGTACTGGTTATACACAGAGTGATGTTACAGTAGAGACTATAAGAAGAATATTCGA
TAGAGAAATTGAGGGTTTTTCGGATGTATTTAGACTAGTGAGTTATAATGATCCTGAAGTAAGATCTGCATCATATTTGA
CCAAAGCAACTGCTGGAATAGTAAACGGCAAGGTAATTTTCTTACTGCCAGGTTCGCCAGACGCTGTAAGATTAGCCATG
ATGGAGTTGATATTGCCAGAAGTTGGCCATTTGCTCTATATTGTTAGGAGAAAATAA

Upstream 100 bases:

>100_bases
ATATAAAGGGAAAGATTCTGGTTAGAGAGAAGTTCAATGACTTGGACTTAGATATAGCGGAGGTAGTAAAGTTAAAATCG
TCCTAAATACTGATTAATCT

Downstream 100 bases:

>100_bases
TTTTAGTTAGCTTATCCATTAAGATCACTTTAATATTTTCAGTTAAGTTCATACTATTTAGTTTGAAGTATAGTAGAACT
AGGTTCTCTATGTTCTCGCC

Product: molybdenum cofactor synthesis protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 178; Mature: 177

Protein sequence:

>178_residues
MSSHKQHRQHAPTNINFYVITISTSRYEKMMKKEPVIDESGDIIKQLIIQSNYNVVGYDLVPDEKVKILKAFANALDNSQ
TDVIISAGGTGYTQSDVTVETIRRIFDREIEGFSDVFRLVSYNDPEVRSASYLTKATAGIVNGKVIFLLPGSPDAVRLAM
MELILPEVGHLLYIVRRK

Sequences:

>Translated_178_residues
MSSHKQHRQHAPTNINFYVITISTSRYEKMMKKEPVIDESGDIIKQLIIQSNYNVVGYDLVPDEKVKILKAFANALDNSQ
TDVIISAGGTGYTQSDVTVETIRRIFDREIEGFSDVFRLVSYNDPEVRSASYLTKATAGIVNGKVIFLLPGSPDAVRLAM
MELILPEVGHLLYIVRRK
>Mature_177_residues
SSHKQHRQHAPTNINFYVITISTSRYEKMMKKEPVIDESGDIIKQLIIQSNYNVVGYDLVPDEKVKILKAFANALDNSQT
DVIISAGGTGYTQSDVTVETIRRIFDREIEGFSDVFRLVSYNDPEVRSASYLTKATAGIVNGKVIFLLPGSPDAVRLAMM
ELILPEVGHLLYIVRRK

Specific function: Maybe involved in the biosynthesis of molybdopterin [H]

COG id: COG0521

COG function: function code H; Molybdopterin biosynthesis enzymes

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the moaB/mog family [H]

Homologues:

Organism=Escherichia coli, GI1787000, Length=157, Percent_Identity=30.5732484076433, Blast_Score=86, Evalue=2e-18,
Organism=Drosophila melanogaster, GI17136978, Length=165, Percent_Identity=33.3333333333333, Blast_Score=78, Evalue=2e-15,
Organism=Drosophila melanogaster, GI24638841, Length=165, Percent_Identity=33.3333333333333, Blast_Score=78, Evalue=2e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020817
- InterPro:   IPR012245
- InterPro:   IPR008284
- InterPro:   IPR001453 [H]

Pfam domain/function: PF00994 MoCF_biosynth [H]

EC number: NA

Molecular weight: Translated: 20006; Mature: 19875

Theoretical pI: Translated: 7.81; Mature: 7.81

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSHKQHRQHAPTNINFYVITISTSRYEKMMKKEPVIDESGDIIKQLIIQSNYNVVGYDL
CCCCHHHHHCCCCCCEEEEEEEEHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCEEEEEC
VPDEKVKILKAFANALDNSQTDVIISAGGTGYTQSDVTVETIRRIFDREIEGFSDVFRLV
CCCHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCCHHHHHHHHHHHCCCHHHHHHHH
SYNDPEVRSASYLTKATAGIVNGKVIFLLPGSPDAVRLAMMELILPEVGHLLYIVRRK
CCCCCCCHHHHHHHHHHHHEECCEEEEEECCCCHHHHHHHHHHHHHHHHHEEEEEECC
>Mature Secondary Structure 
SSHKQHRQHAPTNINFYVITISTSRYEKMMKKEPVIDESGDIIKQLIIQSNYNVVGYDL
CCCHHHHHCCCCCCEEEEEEEEHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCEEEEEC
VPDEKVKILKAFANALDNSQTDVIISAGGTGYTQSDVTVETIRRIFDREIEGFSDVFRLV
CCCHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCCHHHHHHHHHHHCCCHHHHHHHH
SYNDPEVRSASYLTKATAGIVNGKVIFLLPGSPDAVRLAMMELILPEVGHLLYIVRRK
CCCCCCCHHHHHHHHHHHHEECCEEEEEECCCCHHHHHHHHHHHHHHHHHEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Involved in molybdopterin precursor biosynthesis [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12721629 [H]