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The map label for this gene is ycfH [C]

Identifier: 227828329

GI number: 227828329

Start: 1896081

End: 1896827

Strand: Direct

Name: ycfH [C]

Synonym: M1425_2071

Alternate gene names: 227828329

Gene position: 1896081-1896827 (Clockwise)

Preceding gene: 227828328

Following gene: 227828333

Centisome position: 72.68

GC content: 32.4

Gene sequence:

>747_bases
ATGTTAGTGGATTCTCACGCTCATATAGATGTTAGAGACTTTGATGCGGATAGGGATTTTATAGTAAATGAATGTGAAAT
TCTAATAGTAAACGCTGGTGTTGATCTCCAAAGCAATTTAAAAACGCTTAAATTAGCTAGAAAATATAACAATATTATTC
CGGCAATAGGCTTTCATCCTGAGTTTGTGAAAGATAAGATAAATGAGGTAGATAAGTGCGTGGAGTTAACAAGATACGCA
AATATAATAAGTGAGGTTGGTTTAGATTACTTTTGGATAAAGGAGAACGAACTCAAAAGAAAACAAATTGAAATTCTAGA
GAGATTCTTGCAAATAGCTGAGATAGAAGAAAAGCCAGTAATAATCCATATAAGGGGAGGAATGAAAGATTTCTTGGAGA
TGATTACCTCATTCAGAAAAGTTAAATTTGTAATACATAGTTTTGAGGGAAGTATAAAGATAGCTGATAAGGTAATTGAA
CTTGGTGGATTAATATCAATTCCCCCAATAATAGTGAGGGATAAGGATAGACAGAGAGTGGTTAAGGAGATACCTTTAGA
TTTTATTCTTACAGAAACTGATTCACCGTTTATGGGTCCAGAAAAAATGAGTAGAAATAAACCTTGTAATGTAAAGTTTG
CTATAAAGCAAATTAGTCAATTAAAAAGAGTAGAAGAAGATGAAGTTGAGGAAAAAATATACAAGAATTTCCTCGCTTTA
GTTTCTAGTCGTCTTACAACAAGCTAG

Upstream 100 bases:

>100_bases
GTTAAAGTAACCTACGATGAAAGTGAGGGAGTAGTAAAAATACAGTTACTGAAGGAGCCTTGGAAGTAGTTTTTTAAATC
TTTTTTCTCTTTTTCCTTTA

Downstream 100 bases:

>100_bases
CAAAAACATGGATATTATAAAACCTAATGTTGGGATGTAGTATCTGGGTTCTGGTGCAAGCCATGCCAACATTGAGGATG
AGAATATTGCCATTAACAAC

Product: TatD-related deoxyribonuclease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 248; Mature: 248

Protein sequence:

>248_residues
MLVDSHAHIDVRDFDADRDFIVNECEILIVNAGVDLQSNLKTLKLARKYNNIIPAIGFHPEFVKDKINEVDKCVELTRYA
NIISEVGLDYFWIKENELKRKQIEILERFLQIAEIEEKPVIIHIRGGMKDFLEMITSFRKVKFVIHSFEGSIKIADKVIE
LGGLISIPPIIVRDKDRQRVVKEIPLDFILTETDSPFMGPEKMSRNKPCNVKFAIKQISQLKRVEEDEVEEKIYKNFLAL
VSSRLTTS

Sequences:

>Translated_248_residues
MLVDSHAHIDVRDFDADRDFIVNECEILIVNAGVDLQSNLKTLKLARKYNNIIPAIGFHPEFVKDKINEVDKCVELTRYA
NIISEVGLDYFWIKENELKRKQIEILERFLQIAEIEEKPVIIHIRGGMKDFLEMITSFRKVKFVIHSFEGSIKIADKVIE
LGGLISIPPIIVRDKDRQRVVKEIPLDFILTETDSPFMGPEKMSRNKPCNVKFAIKQISQLKRVEEDEVEEKIYKNFLAL
VSSRLTTS
>Mature_248_residues
MLVDSHAHIDVRDFDADRDFIVNECEILIVNAGVDLQSNLKTLKLARKYNNIIPAIGFHPEFVKDKINEVDKCVELTRYA
NIISEVGLDYFWIKENELKRKQIEILERFLQIAEIEEKPVIIHIRGGMKDFLEMITSFRKVKFVIHSFEGSIKIADKVIE
LGGLISIPPIIVRDKDRQRVVKEIPLDFILTETDSPFMGPEKMSRNKPCNVKFAIKQISQLKRVEEDEVEEKIYKNFLAL
VSSRLTTS

Specific function: Unknown

COG id: COG0084

COG function: function code L; Mg-dependent DNase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the tatD DNase family [H]

Homologues:

Organism=Homo sapiens, GI226061614, Length=246, Percent_Identity=32.520325203252, Blast_Score=121, Evalue=6e-28,
Organism=Homo sapiens, GI110349730, Length=259, Percent_Identity=32.046332046332, Blast_Score=120, Evalue=1e-27,
Organism=Homo sapiens, GI110349734, Length=259, Percent_Identity=32.046332046332, Blast_Score=115, Evalue=3e-26,
Organism=Homo sapiens, GI226061853, Length=266, Percent_Identity=31.203007518797, Blast_Score=113, Evalue=1e-25,
Organism=Homo sapiens, GI226061595, Length=228, Percent_Identity=30.7017543859649, Blast_Score=93, Evalue=3e-19,
Organism=Escherichia coli, GI1787342, Length=267, Percent_Identity=28.4644194756554, Blast_Score=88, Evalue=5e-19,
Organism=Escherichia coli, GI87082439, Length=255, Percent_Identity=25.0980392156863, Blast_Score=76, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI71980746, Length=246, Percent_Identity=25.2032520325203, Blast_Score=85, Evalue=4e-17,
Organism=Drosophila melanogaster, GI24648690, Length=238, Percent_Identity=28.1512605042017, Blast_Score=74, Evalue=8e-14,
Organism=Drosophila melanogaster, GI221330018, Length=258, Percent_Identity=25.968992248062, Blast_Score=70, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24586117, Length=258, Percent_Identity=25.968992248062, Blast_Score=70, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015992
- InterPro:   IPR001130
- InterPro:   IPR018228
- InterPro:   IPR012278
- InterPro:   IPR015991 [H]

Pfam domain/function: PF01026 TatD_DNase [H]

EC number: 3.1.21.-

Molecular weight: Translated: 28716; Mature: 28716

Theoretical pI: Translated: 6.38; Mature: 6.38

Prosite motif: PS01137 TATD_1 ; PS01091 TATD_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLVDSHAHIDVRDFDADRDFIVNECEILIVNAGVDLQSNLKTLKLARKYNNIIPAIGFHP
CCCCCCCCEEEEECCCCCCEEECCEEEEEEECCCCCHHHHHHHHHHHHHCCCCCCCCCCH
EFVKDKINEVDKCVELTRYANIISEVGLDYFWIKENELKRKQIEILERFLQIAEIEEKPV
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCHHHHHHHHHHHHHHHHHHCCCCCE
IIHIRGGMKDFLEMITSFRKVKFVIHSFEGSIKIADKVIELGGLISIPPIIVRDKDRQRV
EEEECCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCCCEEEECCHHHHH
VKEIPLDFILTETDSPFMGPEKMSRNKPCNVKFAIKQISQLKRVEEDEVEEKIYKNFLAL
HHHCCCCEEEECCCCCCCCHHHHCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHH
VSSRLTTS
HHHHHCCC
>Mature Secondary Structure
MLVDSHAHIDVRDFDADRDFIVNECEILIVNAGVDLQSNLKTLKLARKYNNIIPAIGFHP
CCCCCCCCEEEEECCCCCCEEECCEEEEEEECCCCCHHHHHHHHHHHHHCCCCCCCCCCH
EFVKDKINEVDKCVELTRYANIISEVGLDYFWIKENELKRKQIEILERFLQIAEIEEKPV
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCHHHHHHHHHHHHHHHHHHCCCCCE
IIHIRGGMKDFLEMITSFRKVKFVIHSFEGSIKIADKVIELGGLISIPPIIVRDKDRQRV
EEEECCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCCCEEEECCHHHHH
VKEIPLDFILTETDSPFMGPEKMSRNKPCNVKFAIKQISQLKRVEEDEVEEKIYKNFLAL
HHHCCCCEEEECCCCCCCCHHHHCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHH
VSSRLTTS
HHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]