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The map label for this gene is rpoN

Identifier: 227828311

GI number: 227828311

Start: 1881924

End: 1882124

Strand: Direct

Name: rpoN

Synonym: M1425_2052

Alternate gene names: 227828311

Gene position: 1881924-1882124 (Clockwise)

Preceding gene: 227828310

Following gene: 227828312

Centisome position: 72.14

GC content: 33.33

Gene sequence:

>201_bases
ATGATGATTCCGATTAGATGTTTTACATGTGGTTCATTGATAGCTGATAAGTGGCAACCATTTATAACAAGAGTTAATGC
AGGAGAAAATCCAGGAAAGGTTCTCGATGACTTAGGTGTAAAAAGATATTGTTGCAGAAGAATGCTTTTATCTCACATAG
ATATAATTAGTGAAGTAATCCACTATACTAGACCAATTTGA

Upstream 100 bases:

>100_bases
TAGGACAATGCTAGCTGGAGATCCAAGGCAGACAGAATCAGAGAAATGGATGAGATATAGTGCAAGGAGATGGAGGCAGA
AATCGTATAGGTGAATCTAT

Downstream 100 bases:

>100_bases
AAGGTGATCAATTTGAGTGAAAAGGAAGAAAGAGGAGGAGAATTAACTGAAGCAGAAAAAGAGGAGTTACGAAAATCCGA
AAAAGGTACAATAATAGAAT

Product: DNA-directed RNA polymerase subunit N

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 66; Mature: 66

Protein sequence:

>66_residues
MMIPIRCFTCGSLIADKWQPFITRVNAGENPGKVLDDLGVKRYCCRRMLLSHIDIISEVIHYTRPI

Sequences:

>Translated_66_residues
MMIPIRCFTCGSLIADKWQPFITRVNAGENPGKVLDDLGVKRYCCRRMLLSHIDIISEVIHYTRPI
>Mature_66_residues
MMIPIRCFTCGSLIADKWQPFITRVNAGENPGKVLDDLGVKRYCCRRMLLSHIDIISEVIHYTRPI

Specific function: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates

COG id: COG1644

COG function: function code K; DNA-directed RNA polymerase, subunit N (RpoN/RPB10)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the archaeal rpoN/eukaryotic RPB10 RNA polymerase subunit family

Homologues:

Organism=Homo sapiens, GI10863925, Length=63, Percent_Identity=49.2063492063492, Blast_Score=83, Evalue=5e-17,
Organism=Caenorhabditis elegans, GI17509857, Length=62, Percent_Identity=51.6129032258064, Blast_Score=82, Evalue=5e-17,
Organism=Saccharomyces cerevisiae, GI6324784, Length=64, Percent_Identity=43.75, Blast_Score=75, Evalue=2e-15,
Organism=Drosophila melanogaster, GI24649759, Length=63, Percent_Identity=52.3809523809524, Blast_Score=83, Evalue=4e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RPON_SULIA (C3N058)

Other databases:

- EMBL:   CP001401
- RefSeq:   YP_002844043.1
- GeneID:   7811949
- GenomeReviews:   CP001401_GR
- KEGG:   sim:M1627_2132
- OMA:   KVVGDKW
- ProtClustDB:   PRK04016
- HAMAP:   MF_00250
- InterPro:   IPR012287
- InterPro:   IPR000268
- InterPro:   IPR020789
- Gene3D:   G3DSA:1.10.10.60
- PANTHER:   PTHR23413:SF2
- PIRSF:   PIRSF005653
- ProDom:   PD006539

Pfam domain/function: PF01194 RNA_pol_N; SSF46924 RNA_pol_N/8_sub

EC number: =2.7.7.6

Molecular weight: Translated: 7606; Mature: 7606

Theoretical pI: Translated: 8.67; Mature: 8.67

Prosite motif: PS01112 RNA_POL_N_8KD

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

6.1 %Cys     (Translated Protein)
4.5 %Met     (Translated Protein)
10.6 %Cys+Met (Translated Protein)
6.1 %Cys     (Mature Protein)
4.5 %Met     (Mature Protein)
10.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMIPIRCFTCGSLIADKWQPFITRVNAGENPGKVLDDLGVKRYCCRRMLLSHIDIISEVI
CCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHCCHHHHHHHHHHHHHHHHHHHHH
HYTRPI
HHHCCC
>Mature Secondary Structure
MMIPIRCFTCGSLIADKWQPFITRVNAGENPGKVLDDLGVKRYCCRRMLLSHIDIISEVI
CCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHCCHHHHHHHHHHHHHHHHHHHHH
HYTRPI
HHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA