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The map label for this gene is ideR [H]

Identifier: 227827738

GI number: 227827738

Start: 1375688

End: 1376326

Strand: Direct

Name: ideR [H]

Synonym: M1425_1469

Alternate gene names: 227827738

Gene position: 1375688-1376326 (Clockwise)

Preceding gene: 227827737

Following gene: 227827739

Centisome position: 52.73

GC content: 34.74

Gene sequence:

>639_bases
ATGGTTGAACTTTCAGAACCCTTGGAAAATTACCTGAAAGAGATGTATGAGATAGAAGAAATTAAGGGCAGTGCTAAAGT
TTCAGAATTAATTTCTATTTTCAATATTTCCCCCGGAACAATAAGCAAAGCGCTAAACAAATTAGAAAAATTAGGATTAA
TAGAAAGAACTAGCGATCGAAAAATAAAGTTAACTGAAGAGGGAAAGAGAATTGCAGAAAGATTAATTAGGTCTCATAGA
CTTAGCGAACGTTTGTTAACAGATATAATTGGACTTGATTGGATAAGAGCTCACGAGTTAGCTCATAGGCTAGAACATAT
TTGGCCAGATGATATATTGGAGAAAATAGATAAATTGCTTGGTTATCCTGCAACTTGTCCTCATGGCCATCCTATAGGAA
ATAGGAAAAAAGTAGACGGAAAGAAATTATCTGAAATAAATATTATTGGTAAATATAAGGTTGTGATGATTGTAAGGGAG
GAAGAATGGGTTTTAAGAGAAGCCACACGACTGGGATTAAAACCCGGCACAGTACTTGAAGTTATTGAAAATAATGGCAC
TGATATAAAAATCAAAGTAGGAGAGAGAATAGAGGAAGTTAGTAAAGTACTTGGTGATCAGGTGTTGGTGGTTGGATGA

Upstream 100 bases:

>100_bases
ACGGAAAGACGGTAAATGCATTAATAGAAGTTTTCGCTAAAGATGAAAGAGCTTCAAATCTAATTGAGAGTATAAAAGCG
AGGATCTACACATAATTCAT

Downstream 100 bases:

>100_bases
ATTAATGAAAAAAATCCTAATTCATATTTACAAATACGGCCCCGATAACCCTTGGTATATGGCGAGAAGACTTTTAGGAG
AAAGTGGATGGGTGGCAAAA

Product: iron (metal) dependent repressor, DtxR family

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 212; Mature: 212

Protein sequence:

>212_residues
MVELSEPLENYLKEMYEIEEIKGSAKVSELISIFNISPGTISKALNKLEKLGLIERTSDRKIKLTEEGKRIAERLIRSHR
LSERLLTDIIGLDWIRAHELAHRLEHIWPDDILEKIDKLLGYPATCPHGHPIGNRKKVDGKKLSEINIIGKYKVVMIVRE
EEWVLREATRLGLKPGTVLEVIENNGTDIKIKVGERIEEVSKVLGDQVLVVG

Sequences:

>Translated_212_residues
MVELSEPLENYLKEMYEIEEIKGSAKVSELISIFNISPGTISKALNKLEKLGLIERTSDRKIKLTEEGKRIAERLIRSHR
LSERLLTDIIGLDWIRAHELAHRLEHIWPDDILEKIDKLLGYPATCPHGHPIGNRKKVDGKKLSEINIIGKYKVVMIVRE
EEWVLREATRLGLKPGTVLEVIENNGTDIKIKVGERIEEVSKVLGDQVLVVG
>Mature_212_residues
MVELSEPLENYLKEMYEIEEIKGSAKVSELISIFNISPGTISKALNKLEKLGLIERTSDRKIKLTEEGKRIAERLIRSHR
LSERLLTDIIGLDWIRAHELAHRLEHIWPDDILEKIDKLLGYPATCPHGHPIGNRKKVDGKKLSEINIIGKYKVVMIVRE
EEWVLREATRLGLKPGTVLEVIENNGTDIKIKVGERIEEVSKVLGDQVLVVG

Specific function: Metal-dependent DNA-binding protein that controls transcription of many genes involved in iron metabolism [H]

COG id: COG1321

COG function: function code K; Mn-dependent transcriptional regulator

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH dtxR-type DNA-binding domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007167
- InterPro:   IPR001367
- InterPro:   IPR022689
- InterPro:   IPR022687
- InterPro:   IPR008988
- InterPro:   IPR011991 [H]

Pfam domain/function: PF02742 Fe_dep_repr_C; PF01325 Fe_dep_repress; PF04023 FeoA [H]

EC number: NA

Molecular weight: Translated: 24139; Mature: 24139

Theoretical pI: Translated: 7.17; Mature: 7.17

Prosite motif: PS50944 HTH_DTXR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVELSEPLENYLKEMYEIEEIKGSAKVSELISIFNISPGTISKALNKLEKLGLIERTSDR
CCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCCC
KIKLTEEGKRIAERLIRSHRLSERLLTDIIGLDWIRAHELAHRLEHIWPDDILEKIDKLL
EEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHH
GYPATCPHGHPIGNRKKVDGKKLSEINIIGKYKVVMIVREEEWVLREATRLGLKPGTVLE
CCCCCCCCCCCCCCCCCCCCCHHHHEEEEEEEEEEEEEECCHHHHHHHHHCCCCCCHHHH
VIENNGTDIKIKVGERIEEVSKVLGDQVLVVG
EEECCCCEEEEEHHHHHHHHHHHHCCCEEEEC
>Mature Secondary Structure
MVELSEPLENYLKEMYEIEEIKGSAKVSELISIFNISPGTISKALNKLEKLGLIERTSDR
CCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCCC
KIKLTEEGKRIAERLIRSHRLSERLLTDIIGLDWIRAHELAHRLEHIWPDDILEKIDKLL
EEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHH
GYPATCPHGHPIGNRKKVDGKKLSEINIIGKYKVVMIVREEEWVLREATRLGLKPGTVLE
CCCCCCCCCCCCCCCCCCCCCHHHHEEEEEEEEEEEEEECCHHHHHHHHHCCCCCCHHHH
VIENNGTDIKIKVGERIEEVSKVLGDQVLVVG
EEECCCCEEEEEHHHHHHHHHHHHCCCEEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]