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The map label for this gene is rpl3p [H]

Identifier: 227827691

GI number: 227827691

Start: 1339987

End: 1341042

Strand: Direct

Name: rpl3p [H]

Synonym: M1425_1420

Alternate gene names: 227827691

Gene position: 1339987-1341042 (Clockwise)

Preceding gene: 227827690

Following gene: 227827692

Centisome position: 51.36

GC content: 37.03

Gene sequence:

>1056_bases
ATGGGTCATCGAAAGTTAGCCTCACCTAGACGTGGATCAGCTGGTCTTAGACCTAGGAAAAGATCATCTGAGTTATTACC
AACACCTAGAACATGGCCACAAATAAATTCGCCGAATCCAAAATTGTTGGGCTTTGTGGGATATAAGGTTGGCATGTCAC
ATGTTTTTATGATTGATGATTGGCCTAACTCTCCTACTAATGGTAAAGAGATATATATGCCAGTTACAGTTCTAGAAGTA
CCTCCAATTATACCGTTGGCTTTGAGAGCTTATGCAGTGGATGGTAAAGGCGAACCAAACGTAATAACAGAATATTGGTC
TCCCTCTTCTTTACAGTTCTTAGATATTACGAGAAGAATTCATTCTTTTTCATCCTTTTTGAAAAATGATGAAAGTAAAA
AGAAGTTTGAGGAAAAGTTTGGTAGTAAGTTAGATCTTATCAAATCTAACTTGGATAGAATAGTCTACTTTAGGCTCTTG
GTAGCTACACAACCTAGGAAGATACCATCATTAGGTAAAAAAGTGCCAGATTTAGTAGAGATCCAGATAGGTGGAGGAGA
AAAGAAAGCACAACTAGATTATGCACTAAACGTTTTAGGAAAAGAAATTTCAATTAAAGACGTTTTCAAGGAGGGTCAAC
TAATAGATGTAGTAGGAGTTACTAAGGGCAAAGGTTTCGCTGGTGTAATAAAAAGGTACAGTGTAGTAGAATTACCTAGA
TGGCATAAGCATAGAAAAGGAAGCAGGAAAATAGGTACTAGAGGTCCGTCTTTAGGGACACCTAGCTATACACCTCAGCC
AGGTCAGTTAGGTTTTCACAGAAGAACAGAATATAATAAGAGAATTATAAAAATTGGTGATGATCCTAAGGAGATAAATC
CTGCAGGTGGTTTTGTAAGGTACGGAATAGTTAGGAACACGTATATTTTGTTGGAAGGTTCTATATTAGGTTCAAAGAAA
AGGCCGATATTCTTAAGAGAGGCTGTTAGACCTTCTTATGTTTTTGAAAACGCTCCTAAGATAACTTATGTTAACCTTTT
AAGTAAGCAAGGGTGA

Upstream 100 bases:

>100_bases
AAGAGGCATTGGCTTATTCTCTGTCTATTCTAAACCTTCTGTTAAGTTAGATTTATAATGCTTGAGTGATAGGTGAAATA
GCAATTAGCGGGGATTAAGA

Downstream 100 bases:

>100_bases
AAGTAAATGTATTTAGAACTAGTTAAGAAAAACTCTGTGATTTTAGATAAAGATGGAAATAAGGTAAAAGAGGTAGAGTT
ACCTTTCATTTTTTCGTTTC

Product: 50S ribosomal protein L3P

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 351; Mature: 350

Protein sequence:

>351_residues
MGHRKLASPRRGSAGLRPRKRSSELLPTPRTWPQINSPNPKLLGFVGYKVGMSHVFMIDDWPNSPTNGKEIYMPVTVLEV
PPIIPLALRAYAVDGKGEPNVITEYWSPSSLQFLDITRRIHSFSSFLKNDESKKKFEEKFGSKLDLIKSNLDRIVYFRLL
VATQPRKIPSLGKKVPDLVEIQIGGGEKKAQLDYALNVLGKEISIKDVFKEGQLIDVVGVTKGKGFAGVIKRYSVVELPR
WHKHRKGSRKIGTRGPSLGTPSYTPQPGQLGFHRRTEYNKRIIKIGDDPKEINPAGGFVRYGIVRNTYILLEGSILGSKK
RPIFLREAVRPSYVFENAPKITYVNLLSKQG

Sequences:

>Translated_351_residues
MGHRKLASPRRGSAGLRPRKRSSELLPTPRTWPQINSPNPKLLGFVGYKVGMSHVFMIDDWPNSPTNGKEIYMPVTVLEV
PPIIPLALRAYAVDGKGEPNVITEYWSPSSLQFLDITRRIHSFSSFLKNDESKKKFEEKFGSKLDLIKSNLDRIVYFRLL
VATQPRKIPSLGKKVPDLVEIQIGGGEKKAQLDYALNVLGKEISIKDVFKEGQLIDVVGVTKGKGFAGVIKRYSVVELPR
WHKHRKGSRKIGTRGPSLGTPSYTPQPGQLGFHRRTEYNKRIIKIGDDPKEINPAGGFVRYGIVRNTYILLEGSILGSKK
RPIFLREAVRPSYVFENAPKITYVNLLSKQG
>Mature_350_residues
GHRKLASPRRGSAGLRPRKRSSELLPTPRTWPQINSPNPKLLGFVGYKVGMSHVFMIDDWPNSPTNGKEIYMPVTVLEVP
PIIPLALRAYAVDGKGEPNVITEYWSPSSLQFLDITRRIHSFSSFLKNDESKKKFEEKFGSKLDLIKSNLDRIVYFRLLV
ATQPRKIPSLGKKVPDLVEIQIGGGEKKAQLDYALNVLGKEISIKDVFKEGQLIDVVGVTKGKGFAGVIKRYSVVELPRW
HKHRKGSRKIGTRGPSLGTPSYTPQPGQLGFHRRTEYNKRIIKIGDDPKEINPAGGFVRYGIVRNTYILLEGSILGSKKR
PIFLREAVRPSYVFENAPKITYVNLLSKQG

Specific function: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit [H]

COG id: COG0087

COG function: function code J; Ribosomal protein L3

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ribosomal protein L3P family [H]

Homologues:

Organism=Homo sapiens, GI4506649, Length=368, Percent_Identity=33.9673913043478, Blast_Score=187, Evalue=1e-47,
Organism=Homo sapiens, GI76496472, Length=353, Percent_Identity=32.2946175637394, Blast_Score=169, Evalue=3e-42,
Organism=Homo sapiens, GI4826988, Length=369, Percent_Identity=31.1653116531165, Blast_Score=157, Evalue=2e-38,
Organism=Caenorhabditis elegans, GI71984538, Length=383, Percent_Identity=33.420365535248, Blast_Score=184, Evalue=8e-47,
Organism=Caenorhabditis elegans, GI71984544, Length=374, Percent_Identity=31.8181818181818, Blast_Score=147, Evalue=1e-35,
Organism=Caenorhabditis elegans, GI71984550, Length=257, Percent_Identity=35.408560311284, Blast_Score=123, Evalue=1e-28,
Organism=Saccharomyces cerevisiae, GI6324637, Length=356, Percent_Identity=33.4269662921348, Blast_Score=150, Evalue=2e-37,
Organism=Drosophila melanogaster, GI17737907, Length=362, Percent_Identity=33.1491712707182, Blast_Score=174, Evalue=1e-43,
Organism=Drosophila melanogaster, GI24645877, Length=345, Percent_Identity=32.463768115942, Blast_Score=156, Evalue=3e-38,
Organism=Drosophila melanogaster, GI24645879, Length=345, Percent_Identity=32.463768115942, Blast_Score=156, Evalue=3e-38,
Organism=Drosophila melanogaster, GI24645875, Length=92, Percent_Identity=40.2173913043478, Blast_Score=72, Evalue=4e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000597
- InterPro:   IPR019928
- InterPro:   IPR019926
- InterPro:   IPR009000 [H]

Pfam domain/function: PF00297 Ribosomal_L3 [H]

EC number: NA

Molecular weight: Translated: 39457; Mature: 39326

Theoretical pI: Translated: 10.79; Mature: 10.79

Prosite motif: PS00474 RIBOSOMAL_L3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
0.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGHRKLASPRRGSAGLRPRKRSSELLPTPRTWPQINSPNPKLLGFVGYKVGMSHVFMIDD
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEEEECCEEEEEEEC
WPNSPTNGKEIYMPVTVLEVPPIIPLALRAYAVDGKGEPNVITEYWSPSSLQFLDITRRI
CCCCCCCCCEEEEEEEEECCCCCCCEEEEEEEECCCCCCCEEEECCCCCCCHHHHHHHHH
HSFSSFLKNDESKKKFEEKFGSKLDLIKSNLDRIVYFRLLVATQPRKIPSLGKKVPDLVE
HHHHHHHHCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHCCCCCEEE
IQIGGGEKKAQLDYALNVLGKEISIKDVFKEGQLIDVVGVTKGKGFAGVIKRYSVVELPR
EEECCCCCHHHHHHHHHHHCCCCCHHHHHCCCCEEEEEEECCCCCHHHHHHHHHHHCCCC
WHKHRKGSRKIGTRGPSLGTPSYTPQPGQLGFHRRTEYNKRIIKIGDDPKEINPAGGFVR
HHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCCCCCCCCEEE
YGIVRNTYILLEGSILGSKKRPIFLREAVRPSYVFENAPKITYVNLLSKQG
EEEEECEEEEEECCEECCCCCCCHHHHHCCCCHHHCCCCCEEEEEEECCCC
>Mature Secondary Structure 
GHRKLASPRRGSAGLRPRKRSSELLPTPRTWPQINSPNPKLLGFVGYKVGMSHVFMIDD
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEEEECCEEEEEEEC
WPNSPTNGKEIYMPVTVLEVPPIIPLALRAYAVDGKGEPNVITEYWSPSSLQFLDITRRI
CCCCCCCCCEEEEEEEEECCCCCCCEEEEEEEECCCCCCCEEEECCCCCCCHHHHHHHHH
HSFSSFLKNDESKKKFEEKFGSKLDLIKSNLDRIVYFRLLVATQPRKIPSLGKKVPDLVE
HHHHHHHHCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHCCCCCEEE
IQIGGGEKKAQLDYALNVLGKEISIKDVFKEGQLIDVVGVTKGKGFAGVIKRYSVVELPR
EEECCCCCHHHHHHHHHHHCCCCCHHHHHCCCCEEEEEEECCCCCHHHHHHHHHHHCCCC
WHKHRKGSRKIGTRGPSLGTPSYTPQPGQLGFHRRTEYNKRIIKIGDDPKEINPAGGFVR
HHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCCCCCCCCEEE
YGIVRNTYILLEGSILGSKKRPIFLREAVRPSYVFENAPKITYVNLLSKQG
EEEEECEEEEEECCEECCCCCCCHHHHHCCCCHHHCCCCCEEEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA