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The map label for this gene is argS [H]

Identifier: 227827629

GI number: 227827629

Start: 1286380

End: 1288257

Strand: Direct

Name: argS [H]

Synonym: M1425_1357

Alternate gene names: 227827629

Gene position: 1286380-1288257 (Clockwise)

Preceding gene: 227827626

Following gene: 227827631

Centisome position: 49.31

GC content: 34.82

Gene sequence:

>1878_bases
GTGGATATAATAGGAAGAGCTAAGAAAGAATTGGCGGAATATGTCGCTGCACAATTAGGTATAAGCGAGGAGGAAGTCTT
TAAAAATATTACATATCCTCCTAGGGAAGAACTTGGCGACTTATCATTAGCGTTACCATCATTAATAAAGCGAAATATAA
ATGAGAAAGCGAAATTATTACAAGAATATAAAGGTGAGTTAATAGAGAGGATAGAAGTAGCCGGAATATATCTTAATGCG
AGGCTTAATCTAAGAAATCTTTTCGTGAGTATCTTTAGCAAACTAGACGATAGTTATGGACTGGAAAAAATCGAAAAGCC
AAAAAGAATAGTAGTTGAACACACGAGCGCTAATCCTATACATCCGTTACATATAGGCCATTTGAGAAATACGATACTTG
GAGATGCGCTTGCTAGAGCGTTAAAAGCTAGAGGTCACTCAGTTAATGTTAGGTTTTACGTTAACGATACTGGGAGGCAA
GTTGCAGTTCTAATTTACGGCCTAAAACTTTTAGGTTTTCCTGATCCAGAGCCAAATGTAAAGAAGGATCTATGGTTGGG
TATAATATATGCCATGACTAATGTAATTTTAGAAATTAGAAAGTTGAGAGAGGAGTTAAAGAAACTTTCAGAGTCAGAGT
ATAGGGAGAAAGTTAGAGAACTAGATGAGCTAATAGTAATAGCGAATGATCTAAGGAATAGAAATGAGGTACTTTTCGAT
AAGTTAGCAGACGCTATAAATGCTAAGGAGGAGCCGGAGAAGGAGATAGGAGAAATCATAAAGAAATACGAAGAGGGTAA
TGATGAACTAAAGGGGATTATTAGAAAGTACATTAGTTATGCGCTAGAAGGCTTTAGTGAAACGTTATCCAAACTTAATA
TAAGATTTGACAATTTCGACTATGAGAGTGACTTGTTATGGGAGAATATGGTTAATGAAGTATTAAAGGCCTTATTGTCT
TCCTCGGCTAAAATACCATATAAGGGAGTAATAGCATTGGACTTAGATAGTTTCTTAGGTGATGAAGCTAGATCTAAGTT
GAGAATTCCAAAAGGGCTCAAGATACCTCCTTTAGTGTTGATGAGATCCGATGGAACTACATTGTATACCGTTAGGGATA
TTGCGTATACAATTTTCAAATTTAATCAGTTTAATGCAGATTTTGTTATAAATGTGATCGCAGAAGAACAATACATTCCG
CAAATACAATTAAGAGGTGCTCTAGAGTTACTCGGATATTCGAGATTTGCGGAAAATTTATTGCATTATTCATATGGGAT
GGTTAACATCCAAGGACTAAGAATGAGTGGAAGACTAGGAAAGATAATAACCATTGACGAGATATATGAAAAACTAGATA
ACATAGTTAGAAATAAGCTGAAAGAGAAAGGTGGTAATATGGAAAATATTGATGATATAGCAAATGCAGCGCTTAGATAC
GCAATTTTGTCAGTTTCTGCAAATAAGCCTTTATCATTTGATTTAAACAGGATAACCAGCTTTGAGCAGAACAGTGGACC
TTATTTACAATATACTTATGCTAGAGCTGCTAACATATTAGCTAAATCTACTGAAAACTTATCTATGGATAAGGTAGACT
TTAGTGATTTAGTTGGAGATAAGAGGAACATATTAATCCTGATAGCTAAATTCCCCGAGGTATTCAAGAATGCTGTAGAT
AACTTAAGGTTAGAAGATTTAGTAGCGTTTCTGAGAGAATTATCTGACATATTCAATAGTTGGTATGATAAAGAGAGAGT
ACTACAAGAACAAGATCCAAGGAAGAGAATGTTAAGATTATATATAGTAAAAGGAGTGTCAGTTGTATTAAAGAACGGGT
TAAGCGTCTTAGGTATAAGGAGCTTAGAAAGGATGTAA

Upstream 100 bases:

>100_bases
TTCCACTATAATCCTCTACTATTAGGATTTCCACCCTTTTCTTCATGGTTATATGATTCTGGTGAGTAAATATTAAAAGT
TATAAGGCATAAAACGTGAT

Downstream 100 bases:

>100_bases
TTAGTTAAAATGAAATACAGAGGATATTTTTCTAACTGGTAGATATTAATCATTAATATAGAGATCACTAGAGTTTTGTT
ACTGATAATATTTTGAAGTC

Product: arginyl-tRNA synthetase

Products: NA

Alternate protein names: Arginine--tRNA ligase; ArgRS [H]

Number of amino acids: Translated: 625; Mature: 625

Protein sequence:

>625_residues
MDIIGRAKKELAEYVAAQLGISEEEVFKNITYPPREELGDLSLALPSLIKRNINEKAKLLQEYKGELIERIEVAGIYLNA
RLNLRNLFVSIFSKLDDSYGLEKIEKPKRIVVEHTSANPIHPLHIGHLRNTILGDALARALKARGHSVNVRFYVNDTGRQ
VAVLIYGLKLLGFPDPEPNVKKDLWLGIIYAMTNVILEIRKLREELKKLSESEYREKVRELDELIVIANDLRNRNEVLFD
KLADAINAKEEPEKEIGEIIKKYEEGNDELKGIIRKYISYALEGFSETLSKLNIRFDNFDYESDLLWENMVNEVLKALLS
SSAKIPYKGVIALDLDSFLGDEARSKLRIPKGLKIPPLVLMRSDGTTLYTVRDIAYTIFKFNQFNADFVINVIAEEQYIP
QIQLRGALELLGYSRFAENLLHYSYGMVNIQGLRMSGRLGKIITIDEIYEKLDNIVRNKLKEKGGNMENIDDIANAALRY
AILSVSANKPLSFDLNRITSFEQNSGPYLQYTYARAANILAKSTENLSMDKVDFSDLVGDKRNILILIAKFPEVFKNAVD
NLRLEDLVAFLRELSDIFNSWYDKERVLQEQDPRKRMLRLYIVKGVSVVLKNGLSVLGIRSLERM

Sequences:

>Translated_625_residues
MDIIGRAKKELAEYVAAQLGISEEEVFKNITYPPREELGDLSLALPSLIKRNINEKAKLLQEYKGELIERIEVAGIYLNA
RLNLRNLFVSIFSKLDDSYGLEKIEKPKRIVVEHTSANPIHPLHIGHLRNTILGDALARALKARGHSVNVRFYVNDTGRQ
VAVLIYGLKLLGFPDPEPNVKKDLWLGIIYAMTNVILEIRKLREELKKLSESEYREKVRELDELIVIANDLRNRNEVLFD
KLADAINAKEEPEKEIGEIIKKYEEGNDELKGIIRKYISYALEGFSETLSKLNIRFDNFDYESDLLWENMVNEVLKALLS
SSAKIPYKGVIALDLDSFLGDEARSKLRIPKGLKIPPLVLMRSDGTTLYTVRDIAYTIFKFNQFNADFVINVIAEEQYIP
QIQLRGALELLGYSRFAENLLHYSYGMVNIQGLRMSGRLGKIITIDEIYEKLDNIVRNKLKEKGGNMENIDDIANAALRY
AILSVSANKPLSFDLNRITSFEQNSGPYLQYTYARAANILAKSTENLSMDKVDFSDLVGDKRNILILIAKFPEVFKNAVD
NLRLEDLVAFLRELSDIFNSWYDKERVLQEQDPRKRMLRLYIVKGVSVVLKNGLSVLGIRSLERM
>Mature_625_residues
MDIIGRAKKELAEYVAAQLGISEEEVFKNITYPPREELGDLSLALPSLIKRNINEKAKLLQEYKGELIERIEVAGIYLNA
RLNLRNLFVSIFSKLDDSYGLEKIEKPKRIVVEHTSANPIHPLHIGHLRNTILGDALARALKARGHSVNVRFYVNDTGRQ
VAVLIYGLKLLGFPDPEPNVKKDLWLGIIYAMTNVILEIRKLREELKKLSESEYREKVRELDELIVIANDLRNRNEVLFD
KLADAINAKEEPEKEIGEIIKKYEEGNDELKGIIRKYISYALEGFSETLSKLNIRFDNFDYESDLLWENMVNEVLKALLS
SSAKIPYKGVIALDLDSFLGDEARSKLRIPKGLKIPPLVLMRSDGTTLYTVRDIAYTIFKFNQFNADFVINVIAEEQYIP
QIQLRGALELLGYSRFAENLLHYSYGMVNIQGLRMSGRLGKIITIDEIYEKLDNIVRNKLKEKGGNMENIDDIANAALRY
AILSVSANKPLSFDLNRITSFEQNSGPYLQYTYARAANILAKSTENLSMDKVDFSDLVGDKRNILILIAKFPEVFKNAVD
NLRLEDLVAFLRELSDIFNSWYDKERVLQEQDPRKRMLRLYIVKGVSVVLKNGLSVLGIRSLERM

Specific function: Unknown

COG id: COG0018

COG function: function code J; Arginyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family [H]

Homologues:

Organism=Homo sapiens, GI197100773, Length=649, Percent_Identity=25.4237288135593, Blast_Score=125, Evalue=1e-28,
Organism=Homo sapiens, GI15149476, Length=305, Percent_Identity=23.6065573770492, Blast_Score=76, Evalue=8e-14,
Organism=Escherichia coli, GI1788184, Length=573, Percent_Identity=24.4328097731239, Blast_Score=137, Evalue=3e-33,
Organism=Caenorhabditis elegans, GI71985061, Length=313, Percent_Identity=23.3226837060703, Blast_Score=67, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6320548, Length=638, Percent_Identity=25.8620689655172, Blast_Score=176, Evalue=8e-45,
Organism=Saccharomyces cerevisiae, GI6321883, Length=609, Percent_Identity=26.9293924466338, Blast_Score=154, Evalue=3e-38,
Organism=Drosophila melanogaster, GI28571570, Length=410, Percent_Identity=23.1707317073171, Blast_Score=86, Evalue=6e-17,

Paralogues:

None

Copy number: 789 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 800 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001278
- InterPro:   IPR015945
- InterPro:   IPR005148
- InterPro:   IPR008909
- InterPro:   IPR014729
- InterPro:   IPR009080 [H]

Pfam domain/function: PF03485 Arg_tRNA_synt_N; PF05746 DALR_1; PF00750 tRNA-synt_1d [H]

EC number: =6.1.1.19 [H]

Molecular weight: Translated: 71487; Mature: 71487

Theoretical pI: Translated: 7.19; Mature: 7.19

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDIIGRAKKELAEYVAAQLGISEEEVFKNITYPPREELGDLSLALPSLIKRNINEKAKLL
CCCCCHHHHHHHHHHHHHHCCCHHHHHHCCCCCCHHHHCHHHHHHHHHHHHCCCHHHHHH
QEYKGELIERIEVAGIYLNARLNLRNLFVSIFSKLDDSYGLEKIEKPKRIVVEHTSANPI
HHHHHHHHHHHHHHEEEEEEECHHHHHHHHHHHHHCHHCCHHHHCCCCEEEEEECCCCCC
HPLHIGHLRNTILGDALARALKARGHSVNVRFYVNDTGRQVAVLIYGLKLLGFPDPEPNV
CCEEHHHHHHHHHHHHHHHHHHHCCCEEEEEEEECCCCCEEHHHHHHHHHHCCCCCCCCC
KKDLWLGIIYAMTNVILEIRKLREELKKLSESEYREKVRELDELIVIANDLRNRNEVLFD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHH
KLADAINAKEEPEKEIGEIIKKYEEGNDELKGIIRKYISYALEGFSETLSKLNIRFDNFD
HHHHHHCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCEECCCC
YESDLLWENMVNEVLKALLSSSAKIPYKGVIALDLDSFLGDEARSKLRIPKGLKIPPLVL
CCHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEHHHHHCHHHHHHCCCCCCCCCCCEEE
MRSDGTTLYTVRDIAYTIFKFNQFNADFVINVIAEEQYIPQIQLRGALELLGYSRFAENL
EECCCCEEEEHHHHHHHHHHHCCCCCCEEEEEECCHHCCCHHHHHHHHHHHHHHHHHHHH
LHYSYGMVNIQGLRMSGRLGKIITIDEIYEKLDNIVRNKLKEKGGNMENIDDIANAALRY
HHHHCCCEEEEEEEECCCCCCEEEHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHH
AILSVSANKPLSFDLNRITSFEQNSGPYLQYTYARAANILAKSTENLSMDKVDFSDLVGD
HHHEECCCCCCCCCHHHHHCCCCCCCCEEEEHHHHHHHHHHHCCCCCCCCCCCHHHHCCC
KRNILILIAKFPEVFKNAVDNLRLEDLVAFLRELSDIFNSWYDKERVLQEQDPRKRMLRL
CCCEEEEEEHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
YIVKGVSVVLKNGLSVLGIRSLERM
HHHHHHHHHHHCCCHHEEHHHHHCC
>Mature Secondary Structure
MDIIGRAKKELAEYVAAQLGISEEEVFKNITYPPREELGDLSLALPSLIKRNINEKAKLL
CCCCCHHHHHHHHHHHHHHCCCHHHHHHCCCCCCHHHHCHHHHHHHHHHHHCCCHHHHHH
QEYKGELIERIEVAGIYLNARLNLRNLFVSIFSKLDDSYGLEKIEKPKRIVVEHTSANPI
HHHHHHHHHHHHHHEEEEEEECHHHHHHHHHHHHHCHHCCHHHHCCCCEEEEEECCCCCC
HPLHIGHLRNTILGDALARALKARGHSVNVRFYVNDTGRQVAVLIYGLKLLGFPDPEPNV
CCEEHHHHHHHHHHHHHHHHHHHCCCEEEEEEEECCCCCEEHHHHHHHHHHCCCCCCCCC
KKDLWLGIIYAMTNVILEIRKLREELKKLSESEYREKVRELDELIVIANDLRNRNEVLFD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHH
KLADAINAKEEPEKEIGEIIKKYEEGNDELKGIIRKYISYALEGFSETLSKLNIRFDNFD
HHHHHHCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCEECCCC
YESDLLWENMVNEVLKALLSSSAKIPYKGVIALDLDSFLGDEARSKLRIPKGLKIPPLVL
CCHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEHHHHHCHHHHHHCCCCCCCCCCCEEE
MRSDGTTLYTVRDIAYTIFKFNQFNADFVINVIAEEQYIPQIQLRGALELLGYSRFAENL
EECCCCEEEEHHHHHHHHHHHCCCCCCEEEEEECCHHCCCHHHHHHHHHHHHHHHHHHHH
LHYSYGMVNIQGLRMSGRLGKIITIDEIYEKLDNIVRNKLKEKGGNMENIDDIANAALRY
HHHHCCCEEEEEEEECCCCCCEEEHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHH
AILSVSANKPLSFDLNRITSFEQNSGPYLQYTYARAANILAKSTENLSMDKVDFSDLVGD
HHHEECCCCCCCCCHHHHHCCCCCCCCEEEEHHHHHHHHHHHCCCCCCCCCCCHHHHCCC
KRNILILIAKFPEVFKNAVDNLRLEDLVAFLRELSDIFNSWYDKERVLQEQDPRKRMLRL
CCCEEEEEEHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
YIVKGVSVVLKNGLSVLGIRSLERM
HHHHHHHHHHHCCCHHEEHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11427726 [H]