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The map label for this gene is yaaU [H]

Identifier: 227827337

GI number: 227827337

Start: 998924

End: 1000300

Strand: Direct

Name: yaaU [H]

Synonym: M1425_1056

Alternate gene names: 227827337

Gene position: 998924-1000300 (Clockwise)

Preceding gene: 227827335

Following gene: 227827338

Centisome position: 38.29

GC content: 39.07

Gene sequence:

>1377_bases
ATGGACATAAGGCATGTATTTAAACCGTTAGATGAGGCAAAGTTCAGTTGGTTCCACGCAAAGTCAATGATAACGACGGG
CATGGGAGTCTTCACCGATGGATACGACTTGTCATCAATTGGTATAGTATTAGGCGCAGTACTAGCGTCCTTTGGAATAA
CTAAAAGTAGTCCAGATTTCGCAATAGTTTCATCTCTACTAACTGGTGCAGCGCTGATTGGTTCTGCAATAGGTGCAATA
ATTTTTGGCTTCCTAGCAAACATGGGTAGGAAGACATTTTACGGGGTTGACGTAGCGCTAATGACAATTGGAGCCTTATT
ACAAGCATTCGTACAAAATCCTATGCAATTAGTATTAGTGAGATTAATTTTAGGGTTAGGAATTGGTGCAGATTACGTTC
TCTCCCCATTAATAATGGCTGAACATAGTAATGCTAAAGATAGGGGTAAGAAGTTGGCCTTAGGTTTTGGGCTGTTCTGG
GGTTTAGGTGCATCCACAGCTGCTGGATTATATCTTATTCTACACGCAATGGGAATACCTTTAGATCTTATATGGAGAAT
TATACTAGCTACTGGAGCTATCCCGGCTGCAGCAGTAATATACCTTAGGAGAAAGATACCAGAAACTACTAGGTATTTAG
GAAGGATAAAGGGTGATATAGACGGTGTTAAGAAGGTGATTAAAGAAGTAACTAAAACTGAGGTTAGCATTATGACAAAC
GTTAAGGATAACGTTAAAGCGTTAGATTACTTCAAAACAAATTGGAGGCCAATATTAATTGCTGCTATACTATGGTTCTT
GTACGATATTCCAGCATACGCTGGAATCTTATTTGGTCCAAGCTTAATAGCGAGTAAGTTGGGTTTAGATCCCGCTACTT
ATCAACTAGTAAACGAGGCATTTTTCATCATTCCCGGTGGGCTAGTAGCACTTTTACTTATAGATAGGGTTGGTAGAAAA
CCATTACAAATAATTGGCTTCATAGGAATGACTTTAGCCTTAACTTCCTTCGCATTTTATATACAATCACCAAACTATAT
CCCCTTAATTGCCATCATCTTTTATGGACTTGAACAATTTTCGTCACAATCTGGGCCAGGTTCAGTATCTGCATCTGGAG
TACTAGGAGTTGAGTTAGCTCCTACTAAGATAAGAAGTATAGCGCAAGGAATTACAGTAGTTGGAGGTAGATTAGGAGCA
ACCTTTGCTTCCTTCATATTCCCCTCACTTTACGTTCAGTATGGACTATCCTTTGCAGTAATATTCGTTGCAATCGCTTC
TGGAATAGCTGCATTATTAACATTCCTATTCATCCCAGAGACTAAAAGCAAATCTCTAGAAGAAGCTTCAAGAGAAATAG
AGTTCGTAAAAGCTTAA

Upstream 100 bases:

>100_bases
GAGACGGAAAAGCGATGTAACTATATAGACTACATAGAAAACTCATCAATTTATAGATTCTATACGACATTCTTAATACC
CTTCATGGTAATTTTCACAC

Downstream 100 bases:

>100_bases
GTTAAACTTTTTTTACCCTAATGGTTTTTTGGTCCTTACGTCAAGATTAGACTTTTATAATTAAAATATAGGTATAATAA
ATATGCACCACCGTCATGGA

Product: general substrate transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 458; Mature: 458

Protein sequence:

>458_residues
MDIRHVFKPLDEAKFSWFHAKSMITTGMGVFTDGYDLSSIGIVLGAVLASFGITKSSPDFAIVSSLLTGAALIGSAIGAI
IFGFLANMGRKTFYGVDVALMTIGALLQAFVQNPMQLVLVRLILGLGIGADYVLSPLIMAEHSNAKDRGKKLALGFGLFW
GLGASTAAGLYLILHAMGIPLDLIWRIILATGAIPAAAVIYLRRKIPETTRYLGRIKGDIDGVKKVIKEVTKTEVSIMTN
VKDNVKALDYFKTNWRPILIAAILWFLYDIPAYAGILFGPSLIASKLGLDPATYQLVNEAFFIIPGGLVALLLIDRVGRK
PLQIIGFIGMTLALTSFAFYIQSPNYIPLIAIIFYGLEQFSSQSGPGSVSASGVLGVELAPTKIRSIAQGITVVGGRLGA
TFASFIFPSLYVQYGLSFAVIFVAIASGIAALLTFLFIPETKSKSLEEASREIEFVKA

Sequences:

>Translated_458_residues
MDIRHVFKPLDEAKFSWFHAKSMITTGMGVFTDGYDLSSIGIVLGAVLASFGITKSSPDFAIVSSLLTGAALIGSAIGAI
IFGFLANMGRKTFYGVDVALMTIGALLQAFVQNPMQLVLVRLILGLGIGADYVLSPLIMAEHSNAKDRGKKLALGFGLFW
GLGASTAAGLYLILHAMGIPLDLIWRIILATGAIPAAAVIYLRRKIPETTRYLGRIKGDIDGVKKVIKEVTKTEVSIMTN
VKDNVKALDYFKTNWRPILIAAILWFLYDIPAYAGILFGPSLIASKLGLDPATYQLVNEAFFIIPGGLVALLLIDRVGRK
PLQIIGFIGMTLALTSFAFYIQSPNYIPLIAIIFYGLEQFSSQSGPGSVSASGVLGVELAPTKIRSIAQGITVVGGRLGA
TFASFIFPSLYVQYGLSFAVIFVAIASGIAALLTFLFIPETKSKSLEEASREIEFVKA
>Mature_458_residues
MDIRHVFKPLDEAKFSWFHAKSMITTGMGVFTDGYDLSSIGIVLGAVLASFGITKSSPDFAIVSSLLTGAALIGSAIGAI
IFGFLANMGRKTFYGVDVALMTIGALLQAFVQNPMQLVLVRLILGLGIGADYVLSPLIMAEHSNAKDRGKKLALGFGLFW
GLGASTAAGLYLILHAMGIPLDLIWRIILATGAIPAAAVIYLRRKIPETTRYLGRIKGDIDGVKKVIKEVTKTEVSIMTN
VKDNVKALDYFKTNWRPILIAAILWFLYDIPAYAGILFGPSLIASKLGLDPATYQLVNEAFFIIPGGLVALLLIDRVGRK
PLQIIGFIGMTLALTSFAFYIQSPNYIPLIAIIFYGLEQFSSQSGPGSVSASGVLGVELAPTKIRSIAQGITVVGGRLGA
TFASFIFPSLYVQYGLSFAVIFVAIASGIAALLTFLFIPETKSKSLEEASREIEFVKA

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family [H]

Homologues:

Organism=Homo sapiens, GI23592238, Length=403, Percent_Identity=25.0620347394541, Blast_Score=67, Evalue=4e-11,
Organism=Escherichia coli, GI1786229, Length=451, Percent_Identity=27.4944567627494, Blast_Score=142, Evalue=3e-35,
Organism=Escherichia coli, GI1790463, Length=456, Percent_Identity=26.5350877192982, Blast_Score=107, Evalue=1e-24,
Organism=Escherichia coli, GI87082159, Length=451, Percent_Identity=25.2771618625277, Blast_Score=103, Evalue=3e-23,
Organism=Escherichia coli, GI1789207, Length=461, Percent_Identity=22.9934924078091, Blast_Score=71, Evalue=1e-13,
Organism=Escherichia coli, GI1788068, Length=466, Percent_Identity=27.2532188841202, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1789312, Length=438, Percent_Identity=24.2009132420091, Blast_Score=69, Evalue=6e-13,
Organism=Caenorhabditis elegans, GI71996338, Length=207, Percent_Identity=31.8840579710145, Blast_Score=66, Evalue=3e-11,
Organism=Saccharomyces cerevisiae, GI6323512, Length=522, Percent_Identity=26.4367816091954, Blast_Score=134, Evalue=4e-32,
Organism=Saccharomyces cerevisiae, GI6319941, Length=474, Percent_Identity=24.8945147679325, Blast_Score=109, Evalue=1e-24,
Organism=Saccharomyces cerevisiae, GI6320705, Length=424, Percent_Identity=23.3490566037736, Blast_Score=77, Evalue=6e-15,
Organism=Saccharomyces cerevisiae, GI6324469, Length=297, Percent_Identity=25.2525252525253, Blast_Score=72, Evalue=1e-13,
Organism=Drosophila melanogaster, GI24581405, Length=426, Percent_Identity=26.2910798122066, Blast_Score=70, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020846
- InterPro:   IPR016196
- InterPro:   IPR005828 [H]

Pfam domain/function: PF00083 Sugar_tr [H]

EC number: NA

Molecular weight: Translated: 49122; Mature: 49122

Theoretical pI: Translated: 9.87; Mature: 9.87

Prosite motif: PS50850 MFS ; PS00216 SUGAR_TRANSPORT_1 ; PS00217 SUGAR_TRANSPORT_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDIRHVFKPLDEAKFSWFHAKSMITTGMGVFTDGYDLSSIGIVLGAVLASFGITKSSPDF
CCHHHHHCCHHHHHHHHHHHHHHHHHCCCCEECCCCHHHHHHHHHHHHHHHCCCCCCCCH
AIVSSLLTGAALIGSAIGAIIFGFLANMGRKTFYGVDVALMTIGALLQAFVQNPMQLVLV
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCHHHHHHH
RLILGLGIGADYVLSPLIMAEHSNAKDRGKKLALGFGLFWGLGASTAAGLYLILHAMGIP
HHHHHCCCCHHHHHHHHHHHCCCCCHHHCCEEEHHHHHHHHCCCHHHHHHHHHHHHHCCC
LDLIWRIILATGAIPAAAVIYLRRKIPETTRYLGRIKGDIDGVKKVIKEVTKTEVSIMTN
HHHHHHHHHHHCCHHHHHHHHHHHHCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHC
VKDNVKALDYFKTNWRPILIAAILWFLYDIPAYAGILFGPSLIASKLGLDPATYQLVNEA
CHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHH
FFIIPGGLVALLLIDRVGRKPLQIIGFIGMTLALTSFAFYIQSPNYIPLIAIIFYGLEQF
HEEECHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHH
SSQSGPGSVSASGVLGVELAPTKIRSIAQGITVVGGRLGATFASFIFPSLYVQYGLSFAV
CCCCCCCCCCCCCEEEEEECHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHH
IFVAIASGIAALLTFLFIPETKSKSLEEASREIEFVKA
HHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCC
>Mature Secondary Structure
MDIRHVFKPLDEAKFSWFHAKSMITTGMGVFTDGYDLSSIGIVLGAVLASFGITKSSPDF
CCHHHHHCCHHHHHHHHHHHHHHHHHCCCCEECCCCHHHHHHHHHHHHHHHCCCCCCCCH
AIVSSLLTGAALIGSAIGAIIFGFLANMGRKTFYGVDVALMTIGALLQAFVQNPMQLVLV
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCHHHHHHH
RLILGLGIGADYVLSPLIMAEHSNAKDRGKKLALGFGLFWGLGASTAAGLYLILHAMGIP
HHHHHCCCCHHHHHHHHHHHCCCCCHHHCCEEEHHHHHHHHCCCHHHHHHHHHHHHHCCC
LDLIWRIILATGAIPAAAVIYLRRKIPETTRYLGRIKGDIDGVKKVIKEVTKTEVSIMTN
HHHHHHHHHHHCCHHHHHHHHHHHHCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHC
VKDNVKALDYFKTNWRPILIAAILWFLYDIPAYAGILFGPSLIASKLGLDPATYQLVNEA
CHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHH
FFIIPGGLVALLLIDRVGRKPLQIIGFIGMTLALTSFAFYIQSPNYIPLIAIIFYGLEQF
HEEECHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHH
SSQSGPGSVSASGVLGVELAPTKIRSIAQGITVVGGRLGATFASFIFPSLYVQYGLSFAV
CCCCCCCCCCCCCEEEEEECHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHH
IFVAIASGIAALLTFLFIPETKSKSLEEASREIEFVKA
HHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1630901; 9278503 [H]