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The map label for this gene is quiP [H]

Identifier: 227827320

GI number: 227827320

Start: 982296

End: 984764

Strand: Direct

Name: quiP [H]

Synonym: M1425_1039

Alternate gene names: 227827320

Gene position: 982296-984764 (Clockwise)

Preceding gene: 227827319

Following gene: 227827321

Centisome position: 37.65

GC content: 36.61

Gene sequence:

>2469_bases
ATGATAGGTGCATTAGTGACTTTATTAGTAATTCTTTCTATTTTTACGACATCTTTATCTATTTTAAATCCCTTTCTTGG
GATTTGGTACTCTTCTGGTAACGTGAATATGCTAAACGAAATCGTTTCCATCCCTGGCTTAAGTGGTAACGTAAACATAT
ACATAGATAGTAATGGAATAGCTCATATTTACGCAAACAATCTTCATGATCTCTTTCTCGCGGAAGGTTATTACGAAGCT
AGTCAAAGATTATTTGAAATAGAATTATTTGGCCTTTTAGCTATGGGAAATTTAAGCTCTTGGGTTGGTGCGAAAGCGTT
ATCCTCGGATATCGCGATGCATTTAATAGGAATACCACAGAATGCGATAATGAGTGCTCAATACTTAAAGCACAACTATC
CAACAATTTACTCATATCTGGAAGCCTTCTCTCAAGGTGTTAATGATTATATAAATACTTTAAACTATAGGGATTTGCCC
TTAGAGTTCAAGTTATTAAACGTTAGACCTTATTATTGGTCACCAGAGTATTCGTTAGCTTTTGGGGAATATATGGGTTG
GAGTTTAACTTCAGGATTTAATGATGAACTTAAATCGGCACTACTTTACACCTACTTCAACTATCCAGAAATCAACGAAA
TTAATCCATATTATCCTCATTTCATAGATGGAAATCTTACTGTCATCCCAGGGGATGGTACAGTTAACGGTTATAATTTA
ACCGATCAAGGGGTTTCACCTCAGTATTTATGGTCGCTAAACTGGTATGAATCATGGGCTACTGGCATAAATAAAGATGA
GTTTAAAGATCTAGTGCCACTAATGAAGTATGCCATACTGAACATTTCAGATCCTTTTATCTTGTTTCCGAAATTTGCAA
GCAACTCATGGGTTATAACTTCTGATTTTTCCACTCAAGGTCCGATACTGGCTAACGACCCGCATTTACCTTTATTTGAT
CCATCAGTCTGGATTCCATTACAACTTATAGCCCCTGCGTTTAACGTAACCGGTTGGTCATTGGTTGGTATACCAGGGGT
TCTAATAGGACATACCGCCTACACTGCATGGGGATTAACGACACCCGAAGGGAGTTCTTCAGACGCTTATGTGGAAATAG
TGAATGGAAGTCAGTATTATTATAATGGTAAATGGTATCAAATGAATGAGTATAATTACACATTAATGGGCAGAACGTAT
ACCGTTTACTATACTAATAATGGACCACTAGTAGCTAGGTATAAGAACTATGGAATAAGTCTGTATTGGTCTGCGTGGAA
AGAGCCGATTCTTACAGTCATTTCCATACTTCTTTTAGATAATTCAACGTCCTTTAATGATTTAATAAATGCAGCAAAGT
ATTGGGTAATTCCCCCACAGAACTTGGCAATTGTAAGTAAGCATCATGCAGGAATAATTGTAGCTGGGCTGTATCCACTT
ATAAATGAGACTTTACCTAATGGTAAAAGCGTATTGGTAGTGGGTGCAAGAACACCATTAAACGGTACTGTTACGAAGTA
CGAACCAATTGGTTATATACCCTTCAAATACTTGCCGCAGACATTTGACCCTGTAAGAGGGTTCGCTTTTGCACCTAATC
AACCCACTGTTTGGATAAATTATCCATTTCCATTTATTGGTGGATTCTGGAGCTCCGGTGGTAGAGCTGAAGATATTTAT
CATTATTTAGAGTACCAACGAAGTGGTAACATTAGTGATATGATGAAATTACAATCCAACGTCACCGATTATTGGGCATC
ATTACTTACTCCCCTTATAATAAAGGCTATGGTCAATAACACGAATGGCAGTATTCAAGGAACTGCATTTAACTATCTAC
GTAATTGGAACTTCACATTTTACCAAAACGAGGTAGCGCCTACAATATATACTTATATTGTTGCCGAAATGGTGAATAAT
AGCATTGCGAAAATACTTAATAAAATGGGTTTAGACATATTAGATATAGCTAGTATACCTTATATTGTACCTGACTTCAT
ATATATTGCACAATACGATCCTACATCAATTTGGGTTAATGGAAACTTCACTAACTTAGTTAGGCAATCGTTTGTTAAAG
CGATCTCGTTATTAGAACAGAATTTAGGAGATAATATAAGTCAATGGTATTGGGGAAGAGTACATTTCTTAGAAATTTAC
AACCCATTGGGATTAAAGGCGCTTTCCGTTGGACCTATTCCAATATTTGGTGATCCTCATACGCTTGCAGTTGGTTCAAC
TCCTTATATTCCCACAGTTCCTTTACCTTATGTAACAGTAGGTTCATCGCTTAGGTTTATAGCTTCACCTTACTCTTCAC
AATTCTATGGAATATTCCCAGGTGGTCCTTCAGAGAGTCTAGTTAGTGCGTTTAGAGAGAATCAATTACCCCTGTGGTTA
TCCTTCAAATATATTTCCTATTCAGGATATAATTACACCATAATAGCAAAAATAACATTGGAGGCGTAA

Upstream 100 bases:

>100_bases
AAACACACTCACCTCTATTGTGGAAACTTTTTTTATGCAATTTACATAATTTAAGTATGATAAGAAGGAGGTGTAGTAGT
TGAAGGGATATAATTACCTC

Downstream 100 bases:

>100_bases
TAGTAATGAAAGGTACAAATACGATTTACATTATCATTTCGTCAATACTATTAGCATATATAATGCAAATTTTTGTATTG
TATCCATTTACAGCAGTAGC

Product: peptidase S45 penicillin amidase

Products: NA

Alternate protein names: AHL acylase quiP; Acyl-HSL acylase quiP; Quorum signal utilization and inactivation protein; Acyl-HSL acylase quiP subunit alpha; Acyl-HSL acylase quiP subunit beta [H]

Number of amino acids: Translated: 822; Mature: 822

Protein sequence:

>822_residues
MIGALVTLLVILSIFTTSLSILNPFLGIWYSSGNVNMLNEIVSIPGLSGNVNIYIDSNGIAHIYANNLHDLFLAEGYYEA
SQRLFEIELFGLLAMGNLSSWVGAKALSSDIAMHLIGIPQNAIMSAQYLKHNYPTIYSYLEAFSQGVNDYINTLNYRDLP
LEFKLLNVRPYYWSPEYSLAFGEYMGWSLTSGFNDELKSALLYTYFNYPEINEINPYYPHFIDGNLTVIPGDGTVNGYNL
TDQGVSPQYLWSLNWYESWATGINKDEFKDLVPLMKYAILNISDPFILFPKFASNSWVITSDFSTQGPILANDPHLPLFD
PSVWIPLQLIAPAFNVTGWSLVGIPGVLIGHTAYTAWGLTTPEGSSSDAYVEIVNGSQYYYNGKWYQMNEYNYTLMGRTY
TVYYTNNGPLVARYKNYGISLYWSAWKEPILTVISILLLDNSTSFNDLINAAKYWVIPPQNLAIVSKHHAGIIVAGLYPL
INETLPNGKSVLVVGARTPLNGTVTKYEPIGYIPFKYLPQTFDPVRGFAFAPNQPTVWINYPFPFIGGFWSSGGRAEDIY
HYLEYQRSGNISDMMKLQSNVTDYWASLLTPLIIKAMVNNTNGSIQGTAFNYLRNWNFTFYQNEVAPTIYTYIVAEMVNN
SIAKILNKMGLDILDIASIPYIVPDFIYIAQYDPTSIWVNGNFTNLVRQSFVKAISLLEQNLGDNISQWYWGRVHFLEIY
NPLGLKALSVGPIPIFGDPHTLAVGSTPYIPTVPLPYVTVGSSLRFIASPYSSQFYGIFPGGPSESLVSAFRENQLPLWL
SFKYISYSGYNYTIIAKITLEA

Sequences:

>Translated_822_residues
MIGALVTLLVILSIFTTSLSILNPFLGIWYSSGNVNMLNEIVSIPGLSGNVNIYIDSNGIAHIYANNLHDLFLAEGYYEA
SQRLFEIELFGLLAMGNLSSWVGAKALSSDIAMHLIGIPQNAIMSAQYLKHNYPTIYSYLEAFSQGVNDYINTLNYRDLP
LEFKLLNVRPYYWSPEYSLAFGEYMGWSLTSGFNDELKSALLYTYFNYPEINEINPYYPHFIDGNLTVIPGDGTVNGYNL
TDQGVSPQYLWSLNWYESWATGINKDEFKDLVPLMKYAILNISDPFILFPKFASNSWVITSDFSTQGPILANDPHLPLFD
PSVWIPLQLIAPAFNVTGWSLVGIPGVLIGHTAYTAWGLTTPEGSSSDAYVEIVNGSQYYYNGKWYQMNEYNYTLMGRTY
TVYYTNNGPLVARYKNYGISLYWSAWKEPILTVISILLLDNSTSFNDLINAAKYWVIPPQNLAIVSKHHAGIIVAGLYPL
INETLPNGKSVLVVGARTPLNGTVTKYEPIGYIPFKYLPQTFDPVRGFAFAPNQPTVWINYPFPFIGGFWSSGGRAEDIY
HYLEYQRSGNISDMMKLQSNVTDYWASLLTPLIIKAMVNNTNGSIQGTAFNYLRNWNFTFYQNEVAPTIYTYIVAEMVNN
SIAKILNKMGLDILDIASIPYIVPDFIYIAQYDPTSIWVNGNFTNLVRQSFVKAISLLEQNLGDNISQWYWGRVHFLEIY
NPLGLKALSVGPIPIFGDPHTLAVGSTPYIPTVPLPYVTVGSSLRFIASPYSSQFYGIFPGGPSESLVSAFRENQLPLWL
SFKYISYSGYNYTIIAKITLEA
>Mature_822_residues
MIGALVTLLVILSIFTTSLSILNPFLGIWYSSGNVNMLNEIVSIPGLSGNVNIYIDSNGIAHIYANNLHDLFLAEGYYEA
SQRLFEIELFGLLAMGNLSSWVGAKALSSDIAMHLIGIPQNAIMSAQYLKHNYPTIYSYLEAFSQGVNDYINTLNYRDLP
LEFKLLNVRPYYWSPEYSLAFGEYMGWSLTSGFNDELKSALLYTYFNYPEINEINPYYPHFIDGNLTVIPGDGTVNGYNL
TDQGVSPQYLWSLNWYESWATGINKDEFKDLVPLMKYAILNISDPFILFPKFASNSWVITSDFSTQGPILANDPHLPLFD
PSVWIPLQLIAPAFNVTGWSLVGIPGVLIGHTAYTAWGLTTPEGSSSDAYVEIVNGSQYYYNGKWYQMNEYNYTLMGRTY
TVYYTNNGPLVARYKNYGISLYWSAWKEPILTVISILLLDNSTSFNDLINAAKYWVIPPQNLAIVSKHHAGIIVAGLYPL
INETLPNGKSVLVVGARTPLNGTVTKYEPIGYIPFKYLPQTFDPVRGFAFAPNQPTVWINYPFPFIGGFWSSGGRAEDIY
HYLEYQRSGNISDMMKLQSNVTDYWASLLTPLIIKAMVNNTNGSIQGTAFNYLRNWNFTFYQNEVAPTIYTYIVAEMVNN
SIAKILNKMGLDILDIASIPYIVPDFIYIAQYDPTSIWVNGNFTNLVRQSFVKAISLLEQNLGDNISQWYWGRVHFLEIY
NPLGLKALSVGPIPIFGDPHTLAVGSTPYIPTVPLPYVTVGSSLRFIASPYSSQFYGIFPGGPSESLVSAFRENQLPLWL
SFKYISYSGYNYTIIAKITLEA

Specific function: Catalyzes the deacylation of acyl-homoserine lactone (AHL or acyl-HSL), releasing homoserine lactone (HSL) and the corresponding fatty acid. Possesses a specificity for the degradation of long-chain acyl-HSLs (side chains of seven or more carbons in lengt

COG id: COG2366

COG function: function code R; Protein related to penicillin acylase

Gene ontology:

Cell location: Periplasm (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S45 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014395
- InterPro:   IPR002692 [H]

Pfam domain/function: PF01804 Penicil_amidase [H]

EC number: =3.5.1.97 [H]

Molecular weight: Translated: 92433; Mature: 92433

Theoretical pI: Translated: 4.85; Mature: 4.85

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIGALVTLLVILSIFTTSLSILNPFLGIWYSSGNVNMLNEIVSIPGLSGNVNIYIDSNGI
CHHHHHHHHHHHHHHHHHHHHHCHHHEEEECCCCHHHHHHHHHCCCCCCCEEEEECCCCE
AHIYANNLHDLFLAEGYYEASQRLFEIELFGLLAMGNLSSWVGAKALSSDIAMHLIGIPQ
EEEEECCCCEEEEECCHHHHCCEEEEEEEEEEEEECCCHHHHHHHHHHHCCEEEEEECCH
NAIMSAQYLKHNYPTIYSYLEAFSQGVNDYINTLNYRDLPLEFKLLNVRPYYWSPEYSLA
HHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEEEEEEEECCCCCEE
FGEYMGWSLTSGFNDELKSALLYTYFNYPEINEINPYYPHFIDGNLTVIPGDGTVNGYNL
HHHHCCCEECCCCCHHHHHEEEEEEECCCCCCCCCCCCCEEECCEEEEECCCCCCCCCCC
TDQGVSPQYLWSLNWYESWATGINKDEFKDLVPLMKYAILNISDPFILFPKFASNSWVIT
CCCCCCCCEEEEECCHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCEEEE
SDFSTQGPILANDPHLPLFDPSVWIPLQLIAPAFNVTGWSLVGIPGVLIGHTAYTAWGLT
ECCCCCCCEEECCCCCCEECCCCEEEHEEECCCCCCCCEEEECCCCEEECCCEEEEECCC
TPEGSSSDAYVEIVNGSQYYYNGKWYQMNEYNYTLMGRTYTVYYTNNGPLVARYKNYGIS
CCCCCCCCCEEEEECCCEEEECCEEEEECCCEEEEECCEEEEEEECCCCEEEEEECCCEE
LYWSAWKEPILTVISILLLDNSTSFNDLINAAKYWVIPPQNLAIVSKHHAGIIVAGLYPL
EEEHHHHHHHHHHHHHHHCCCCCCHHHHHCCCEEEEECCCCEEEEEECCCCEEEEEHHHH
INETLPNGKSVLVVGARTPLNGTVTKYEPIGYIPFKYLPQTFDPVRGFAFAPNQPTVWIN
HHHHCCCCCEEEEEECCCCCCCCEEEECCCCCCCHHHCCCCCCCCCCEEECCCCCEEEEE
YPFPFIGGFWSSGGRAEDIYHYLEYQRSGNISDMMKLQSNVTDYWASLLTPLIIKAMVNN
CCCHHHCCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
TNGSIQGTAFNYLRNWNFTFYQNEVAPTIYTYIVAEMVNNSIAKILNKMGLDILDIASIP
CCCCEEEEEEHHHHCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCC
YIVPDFIYIAQYDPTSIWVNGNFTNLVRQSFVKAISLLEQNLGDNISQWYWGRVHFLEIY
CCCCCEEEEEEECCCEEEECCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCEEEEEEEE
NPLGLKALSVGPIPIFGDPHTLAVGSTPYIPTVPLPYVTVGSSLRFIASPYSSQFYGIFP
CCCCCEEEEECCEEECCCCCEEEECCCCCCCCCCCCEEEECCCEEEEECCCCCCEEEEEC
GGPSESLVSAFRENQLPLWLSFKYISYSGYNYTIIAKITLEA
CCCHHHHHHHHHHCCCCEEEEEEEEEECCCCEEEEEEEEECC
>Mature Secondary Structure
MIGALVTLLVILSIFTTSLSILNPFLGIWYSSGNVNMLNEIVSIPGLSGNVNIYIDSNGI
CHHHHHHHHHHHHHHHHHHHHHCHHHEEEECCCCHHHHHHHHHCCCCCCCEEEEECCCCE
AHIYANNLHDLFLAEGYYEASQRLFEIELFGLLAMGNLSSWVGAKALSSDIAMHLIGIPQ
EEEEECCCCEEEEECCHHHHCCEEEEEEEEEEEEECCCHHHHHHHHHHHCCEEEEEECCH
NAIMSAQYLKHNYPTIYSYLEAFSQGVNDYINTLNYRDLPLEFKLLNVRPYYWSPEYSLA
HHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEEEEEEEECCCCCEE
FGEYMGWSLTSGFNDELKSALLYTYFNYPEINEINPYYPHFIDGNLTVIPGDGTVNGYNL
HHHHCCCEECCCCCHHHHHEEEEEEECCCCCCCCCCCCCEEECCEEEEECCCCCCCCCCC
TDQGVSPQYLWSLNWYESWATGINKDEFKDLVPLMKYAILNISDPFILFPKFASNSWVIT
CCCCCCCCEEEEECCHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCEEEE
SDFSTQGPILANDPHLPLFDPSVWIPLQLIAPAFNVTGWSLVGIPGVLIGHTAYTAWGLT
ECCCCCCCEEECCCCCCEECCCCEEEHEEECCCCCCCCEEEECCCCEEECCCEEEEECCC
TPEGSSSDAYVEIVNGSQYYYNGKWYQMNEYNYTLMGRTYTVYYTNNGPLVARYKNYGIS
CCCCCCCCCEEEEECCCEEEECCEEEEECCCEEEEECCEEEEEEECCCCEEEEEECCCEE
LYWSAWKEPILTVISILLLDNSTSFNDLINAAKYWVIPPQNLAIVSKHHAGIIVAGLYPL
EEEHHHHHHHHHHHHHHHCCCCCCHHHHHCCCEEEEECCCCEEEEEECCCCEEEEEHHHH
INETLPNGKSVLVVGARTPLNGTVTKYEPIGYIPFKYLPQTFDPVRGFAFAPNQPTVWIN
HHHHCCCCCEEEEEECCCCCCCCEEEECCCCCCCHHHCCCCCCCCCCEEECCCCCEEEEE
YPFPFIGGFWSSGGRAEDIYHYLEYQRSGNISDMMKLQSNVTDYWASLLTPLIIKAMVNN
CCCHHHCCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
TNGSIQGTAFNYLRNWNFTFYQNEVAPTIYTYIVAEMVNNSIAKILNKMGLDILDIASIP
CCCCEEEEEEHHHHCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCC
YIVPDFIYIAQYDPTSIWVNGNFTNLVRQSFVKAISLLEQNLGDNISQWYWGRVHFLEIY
CCCCCEEEEEEECCCEEEECCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCEEEEEEEE
NPLGLKALSVGPIPIFGDPHTLAVGSTPYIPTVPLPYVTVGSSLRFIASPYSSQFYGIFP
CCCCCEEEEECCEEECCCCCEEEECCCCCCCCCCCCEEEECCCEEEEECCCCCCEEEEEC
GGPSESLVSAFRENQLPLWLSFKYISYSGYNYTIIAKITLEA
CCCHHHHHHHHHHCCCCEEEEEEEEEECCCCEEEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]