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The map label for this gene is 227826706

Identifier: 227826706

GI number: 227826706

Start: 260303

End: 261445

Strand: Direct

Name: 227826706

Synonym: M1425_0298

Alternate gene names: NA

Gene position: 260303-261445 (Clockwise)

Preceding gene: 227826704

Following gene: 227826707

Centisome position: 9.98

GC content: 37.8

Gene sequence:

>1143_bases
ATGATTGTAGGATTTGCTGGAAAACTGTCTAAAAATTATGAGAAAGATGGAATAGAGCTATTAAAAGAAGCCATTGATGA
GGCCCTAGAGATGGCAGGATTAAATTATGCTGATATTGATGGAATAATGGCGAATATAGGTAGAGGTTCATTTCACGGTA
ATAAGACATATCTTAATCCTCCTGCCCAGATAAGCGAATATTTTGGAATTAAGCCAAAAATTATAGACCATGTGCAATAC
GGTGGACCCTCAGTATTATCAATGATATATAGGGCATATAAGGCAATTAAGACGGGGGATGCAGAGACGATACTTTGCAT
ACAAGGAGGGAAGATATCACATTTAAAAGATAATCATTTCCAAAAAACAGATATAATAGATAGCCCCTTTGATGATTACA
TAAAGATTTACGACCAGATGTCTCCAATATCTGATTATGCAATGGTTACTTATAGACACTCCAAACTCTTCGGTACAACT
GATGAACAAAGGGCAGAAATTGCAGTAATGCAGAGATATAATGCAAGTTTCAATCCTAAAGCTCTATTCAGAAATCCTAT
TACAGTAGAAGACGTTTTGCAATCTAGGATAGTTTCTTATCCTTTACATCTTCTTGAAATAGTTTACCCTATAGACGGCT
TTCACGTTTTTGTAGTAAGTAAAAGAAGTAGCAAATCAGCCCTTAGGAATATTGATATTTTAGCATATGGAGAGGCTCAT
TGGCCAAATCCACCAGCTGAATGGGATGATATAATTTATACTCCAGCAATTGAAAGCGCGAAAAGGGCTTCATTTGACCT
TAATCGTGTAGACACCTTTCAACTTTACGACTCATTCACCATAACCGTGATGCTACAAATGGAGGACATAGGGTTAGTTG
AGAAGGGTAAGGTTGGGCAATTCGTTGAATCCCATGACTTAACTTTCAAGGGTGATGTCCCCATTAATACTGGGGGTGGT
AGTTTGAATACTGGTCAACCCGCTTACATGAGTGGTGGTGTTATTTTAGAAGAAGCTTTACTTCAATTAAACGATATGGC
AGATGGCCATCAAGTTAAGGGTACTGACGTTGTATTCCTAAATGGAATTGGGTGGTGGAGTAGAAGGCATAGTGTAACTT
TAGTATTGGGTGAGCGGAAATGA

Upstream 100 bases:

>100_bases
ACTCAGCCATAATAAAAGTTAATCTGAACTTCTTAATAAGTATTATTAGAAGGAGAAATTTGAACAAGATTTTTTAATAA
GTAGTAAATCATGTTTAACA

Downstream 100 bases:

>100_bases
GAGATGACGAGATAAGAGAAACATACTTTAAATATTTCAATGAAGAGAAATTACCATTTATTCAATGTAAAAATTGTGGT
CATAGGTTTTACTATCCAAG

Product: acetyl-CoA C-acetyltransferase (acetoacetyl-CoAthiolase) (AcaB-6)

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 380; Mature: 380

Protein sequence:

>380_residues
MIVGFAGKLSKNYEKDGIELLKEAIDEALEMAGLNYADIDGIMANIGRGSFHGNKTYLNPPAQISEYFGIKPKIIDHVQY
GGPSVLSMIYRAYKAIKTGDAETILCIQGGKISHLKDNHFQKTDIIDSPFDDYIKIYDQMSPISDYAMVTYRHSKLFGTT
DEQRAEIAVMQRYNASFNPKALFRNPITVEDVLQSRIVSYPLHLLEIVYPIDGFHVFVVSKRSSKSALRNIDILAYGEAH
WPNPPAEWDDIIYTPAIESAKRASFDLNRVDTFQLYDSFTITVMLQMEDIGLVEKGKVGQFVESHDLTFKGDVPINTGGG
SLNTGQPAYMSGGVILEEALLQLNDMADGHQVKGTDVVFLNGIGWWSRRHSVTLVLGERK

Sequences:

>Translated_380_residues
MIVGFAGKLSKNYEKDGIELLKEAIDEALEMAGLNYADIDGIMANIGRGSFHGNKTYLNPPAQISEYFGIKPKIIDHVQY
GGPSVLSMIYRAYKAIKTGDAETILCIQGGKISHLKDNHFQKTDIIDSPFDDYIKIYDQMSPISDYAMVTYRHSKLFGTT
DEQRAEIAVMQRYNASFNPKALFRNPITVEDVLQSRIVSYPLHLLEIVYPIDGFHVFVVSKRSSKSALRNIDILAYGEAH
WPNPPAEWDDIIYTPAIESAKRASFDLNRVDTFQLYDSFTITVMLQMEDIGLVEKGKVGQFVESHDLTFKGDVPINTGGG
SLNTGQPAYMSGGVILEEALLQLNDMADGHQVKGTDVVFLNGIGWWSRRHSVTLVLGERK
>Mature_380_residues
MIVGFAGKLSKNYEKDGIELLKEAIDEALEMAGLNYADIDGIMANIGRGSFHGNKTYLNPPAQISEYFGIKPKIIDHVQY
GGPSVLSMIYRAYKAIKTGDAETILCIQGGKISHLKDNHFQKTDIIDSPFDDYIKIYDQMSPISDYAMVTYRHSKLFGTT
DEQRAEIAVMQRYNASFNPKALFRNPITVEDVLQSRIVSYPLHLLEIVYPIDGFHVFVVSKRSSKSALRNIDILAYGEAH
WPNPPAEWDDIIYTPAIESAKRASFDLNRVDTFQLYDSFTITVMLQMEDIGLVEKGKVGQFVESHDLTFKGDVPINTGGG
SLNTGQPAYMSGGVILEEALLQLNDMADGHQVKGTDVVFLNGIGWWSRRHSVTLVLGERK

Specific function: Unknown

COG id: COG0183

COG function: function code I; Acetyl-CoA acetyltransferase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI19923233, Length=367, Percent_Identity=22.3433242506812, Blast_Score=66, Evalue=5e-11,
Organism=Homo sapiens, GI302344760, Length=295, Percent_Identity=22.3728813559322, Blast_Score=66, Evalue=6e-11,
Organism=Homo sapiens, GI302344767, Length=295, Percent_Identity=22.3728813559322, Blast_Score=66, Evalue=7e-11,
Organism=Drosophila melanogaster, GI19921506, Length=369, Percent_Identity=22.2222222222222, Blast_Score=84, Evalue=2e-16,
Organism=Drosophila melanogaster, GI24585051, Length=369, Percent_Identity=21.9512195121951, Blast_Score=82, Evalue=6e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002155
- InterPro:   IPR016039
- InterPro:   IPR016038
- InterPro:   IPR020617
- InterPro:   IPR020616 [H]

Pfam domain/function: PF02803 Thiolase_C; PF00108 Thiolase_N [H]

EC number: NA

Molecular weight: Translated: 42456; Mature: 42456

Theoretical pI: Translated: 5.59; Mature: 5.59

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIVGFAGKLSKNYEKDGIELLKEAIDEALEMAGLNYADIDGIMANIGRGSFHGNKTYLNP
CEEECCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCCCEEECC
PAQISEYFGIKPKIIDHVQYGGPSVLSMIYRAYKAIKTGDAETILCIQGGKISHLKDNHF
CHHHHHHCCCCCHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCEEEEEECCEECCCCCCCC
QKTDIIDSPFDDYIKIYDQMSPISDYAMVTYRHSKLFGTTDEQRAEIAVMQRYNASFNPK
CCCCCCCCCHHHHHHHHHHCCCCCCEEEEEEECCEECCCCCHHHHHHHHHHHHCCCCCCH
ALFRNPITVEDVLQSRIVSYPLHLLEIVYPIDGFHVFVVSKRSSKSALRNIDILAYGEAH
HHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCHHHHHCCEEEEECCCC
WPNPPAEWDDIIYTPAIESAKRASFDLNRVDTFQLYDSFTITVMLQMEDIGLVEKGKVGQ
CCCCCCCCCCEEECCCCCCHHHCCCCCCCCEEEEEECCEEEEEEEEECCCCCCCCCCCCC
FVESHDLTFKGDVPINTGGGSLNTGQPAYMSGGVILEEALLQLNDMADGHQVKGTDVVFL
HHHHCCCEEECCCCEECCCCCCCCCCCCEEECCHHHHHHHHHHHCCCCCCEECCCEEEEE
NGIGWWSRRHSVTLVLGERK
ECCCCCCCCCEEEEEEECCC
>Mature Secondary Structure
MIVGFAGKLSKNYEKDGIELLKEAIDEALEMAGLNYADIDGIMANIGRGSFHGNKTYLNP
CEEECCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCCCEEECC
PAQISEYFGIKPKIIDHVQYGGPSVLSMIYRAYKAIKTGDAETILCIQGGKISHLKDNHF
CHHHHHHCCCCCHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCEEEEEECCEECCCCCCCC
QKTDIIDSPFDDYIKIYDQMSPISDYAMVTYRHSKLFGTTDEQRAEIAVMQRYNASFNPK
CCCCCCCCCHHHHHHHHHHCCCCCCEEEEEEECCEECCCCCHHHHHHHHHHHHCCCCCCH
ALFRNPITVEDVLQSRIVSYPLHLLEIVYPIDGFHVFVVSKRSSKSALRNIDILAYGEAH
HHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCHHHHHCCEEEEECCCC
WPNPPAEWDDIIYTPAIESAKRASFDLNRVDTFQLYDSFTITVMLQMEDIGLVEKGKVGQ
CCCCCCCCCCEEECCCCCCHHHCCCCCCCCEEEEEECCEEEEEEEEECCCCCCCCCCCCC
FVESHDLTFKGDVPINTGGGSLNTGQPAYMSGGVILEEALLQLNDMADGHQVKGTDVVFL
HHHHCCCEEECCCCEECCCCCCCCCCCCEEECCHHHHHHHHHHHCCCCCCEECCCEEEEE
NGIGWWSRRHSVTLVLGERK
ECCCCCCCCCEEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9371463 [H]