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The map label for this gene is 227826648

Identifier: 227826648

GI number: 227826648

Start: 206087

End: 207445

Strand: Direct

Name: 227826648

Synonym: M1425_0239

Alternate gene names: NA

Gene position: 206087-207445 (Clockwise)

Preceding gene: 227826645

Following gene: 227826649

Centisome position: 7.9

GC content: 37.53

Gene sequence:

>1359_bases
ATGTCAGAGATACGCGAGTTAAAGAAACCCATACGTGAAAAAGCAAGTATTCATAGTCATATTAAAGGTTTAGGTTTAGA
TGATAATGGTAAAGCTAAGTTTATTGCAGATGGGCTAGTTGGCCAAGCTGAGGCCCGAGAGGCTGCAGGAGTAGTTGTAC
AACTGATAAAACAAGGAAAAATGTCGGGAAAAGGGATACTATTTGTTGGTCCTCCGGGTACTGGAAAAACTGCATTAGCA
GTAGCGATTGCCAGAGAGTTGGGTGAAGATACTCCATTTACTGCAATTAACGCTTCTGAAATATATTCTACAGAACTTAA
GAAGACTGAGATACTAACCCAATTGATAAGAAAATCAATAGGTGTCAGAATTAGGGAAAAGAGACTGGTGTATGAAGGCG
TTGTAAAGGATAGGAAGATTAAGGTTGCTAGAAGTAGATTAAATCCCTATTCCCAAGCTCCAGTTGAGGCTCAAATAACT
TTAACCACTAAAGACGATGAAAGGACGTTGTCAGTAGGTGAGGAAATAGCACAACAACTCGTATCCTTAGGCGTTAAGAA
AGGCGACGTTATCATGATTGATGCTCAAACTGGACAAGTTATAGTTGAGGGTAAGGCTAAGGGTTTTGAAGGTGCTAAAA
CTTATGATATAGAGACTACGAAAGTACTAGAGATACCTACTGGTCCGGTGAGAAAAGAAAAGGAAATAACAACTACACTC
ACCTTAAACGATTTAGACCTGAATTTAGCTGCTAGAAATCTAGCCGTTACAGCTATCTTCTCGTTCTTTACGGAAAGAGA
AATAAATGAGGACGTTAGAAAAGAGGTAGATAGACTAGTTAAGGATTGGATTAACCAAGGTAGGGCGGAATTGGTAGTTG
GAGTGCTATTCATTGATGATGCTCATACGCTCGATTTAGAAGCATTTTCTTTCCTAACTAGAGCCTTAGAGTCCGAATTA
GCACCAATACTGATCTTAGCAACCAACAGGGGGCTAACTAAAATTAGAGGAACTGATATAGAATCTCCTCACGGGATTCC
TCTTGACCTATTGGATAGACTGCTGATAATACCAACTAGACCTTATAATGCTGATGAAATTAAAGAAATAATCAAGATTA
GAGCTGATGAATTAGAAATTGAATTAGATCCTCAAGCTTTAGAGGAATTAACTAAAATAGGTGTTGAAAATAGTTTGAGA
TACTCTGTTCAACTGTTAGAACCATCTCTTATAATTGCTCAAAGAAATAATAGGAGTATTATAAAGGTTGAAGATGTAGT
GGTAGCTTCAAAGCTATTCTCAGATGTTAAGAGAAGTGTAAAGTTTGTAAAGGAGTATGAGAATCTATTATTGAAATGA

Upstream 100 bases:

>100_bases
CCTTTGACCGTAATATTTTATATGCAAGCTTTCTCGCTATACAAGGCCTCATAGATTTAGAGTTAATCTCAAAAACTTTA
TTATATATTATTATTGTGAG

Downstream 100 bases:

>100_bases
TGTCTGGTGACGGCTCTGAGCCAGTGATGTCACCAAAAAGTCTGATCAATATTTTTTAAATATCCAAAAACTTAGATTCT
GGTGTGAAAGTAGGTTTAGT

Product: TIP49 domain protein

Products: NA

Alternate protein names: TIP49 Domain Protein; TIP49-Like Protein; Tbp-Interacting Protein Tip; TIP49 Domain-Containing Protein; DNA Helicase; TBP-Interacting Proten; TIP49 C-Terminal Domain Family Protein; DNA Helicase TIP; TIP49-Like

Number of amino acids: Translated: 452; Mature: 451

Protein sequence:

>452_residues
MSEIRELKKPIREKASIHSHIKGLGLDDNGKAKFIADGLVGQAEAREAAGVVVQLIKQGKMSGKGILFVGPPGTGKTALA
VAIARELGEDTPFTAINASEIYSTELKKTEILTQLIRKSIGVRIREKRLVYEGVVKDRKIKVARSRLNPYSQAPVEAQIT
LTTKDDERTLSVGEEIAQQLVSLGVKKGDVIMIDAQTGQVIVEGKAKGFEGAKTYDIETTKVLEIPTGPVRKEKEITTTL
TLNDLDLNLAARNLAVTAIFSFFTEREINEDVRKEVDRLVKDWINQGRAELVVGVLFIDDAHTLDLEAFSFLTRALESEL
APILILATNRGLTKIRGTDIESPHGIPLDLLDRLLIIPTRPYNADEIKEIIKIRADELEIELDPQALEELTKIGVENSLR
YSVQLLEPSLIIAQRNNRSIIKVEDVVVASKLFSDVKRSVKFVKEYENLLLK

Sequences:

>Translated_452_residues
MSEIRELKKPIREKASIHSHIKGLGLDDNGKAKFIADGLVGQAEAREAAGVVVQLIKQGKMSGKGILFVGPPGTGKTALA
VAIARELGEDTPFTAINASEIYSTELKKTEILTQLIRKSIGVRIREKRLVYEGVVKDRKIKVARSRLNPYSQAPVEAQIT
LTTKDDERTLSVGEEIAQQLVSLGVKKGDVIMIDAQTGQVIVEGKAKGFEGAKTYDIETTKVLEIPTGPVRKEKEITTTL
TLNDLDLNLAARNLAVTAIFSFFTEREINEDVRKEVDRLVKDWINQGRAELVVGVLFIDDAHTLDLEAFSFLTRALESEL
APILILATNRGLTKIRGTDIESPHGIPLDLLDRLLIIPTRPYNADEIKEIIKIRADELEIELDPQALEELTKIGVENSLR
YSVQLLEPSLIIAQRNNRSIIKVEDVVVASKLFSDVKRSVKFVKEYENLLLK
>Mature_451_residues
SEIRELKKPIREKASIHSHIKGLGLDDNGKAKFIADGLVGQAEAREAAGVVVQLIKQGKMSGKGILFVGPPGTGKTALAV
AIARELGEDTPFTAINASEIYSTELKKTEILTQLIRKSIGVRIREKRLVYEGVVKDRKIKVARSRLNPYSQAPVEAQITL
TTKDDERTLSVGEEIAQQLVSLGVKKGDVIMIDAQTGQVIVEGKAKGFEGAKTYDIETTKVLEIPTGPVRKEKEITTTLT
LNDLDLNLAARNLAVTAIFSFFTEREINEDVRKEVDRLVKDWINQGRAELVVGVLFIDDAHTLDLEAFSFLTRALESELA
PILILATNRGLTKIRGTDIESPHGIPLDLLDRLLIIPTRPYNADEIKEIIKIRADELEIELDPQALEELTKIGVENSLRY
SVQLLEPSLIIAQRNNRSIIKVEDVVVASKLFSDVKRSVKFVKEYENLLLK

Specific function: Unknown

COG id: COG1224

COG function: function code K; DNA helicase TIP49, TBP-interacting protein

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI5730023, Length=451, Percent_Identity=43.6807095343681, Blast_Score=375, Evalue=1e-104,
Organism=Homo sapiens, GI4506753, Length=458, Percent_Identity=44.9781659388646, Blast_Score=366, Evalue=1e-101,
Organism=Caenorhabditis elegans, GI17542510, Length=435, Percent_Identity=42.9885057471264, Blast_Score=351, Evalue=4e-97,
Organism=Caenorhabditis elegans, GI17558290, Length=452, Percent_Identity=38.0530973451327, Blast_Score=295, Evalue=3e-80,
Organism=Saccharomyces cerevisiae, GI6325021, Length=433, Percent_Identity=45.0346420323326, Blast_Score=362, Evalue=1e-101,
Organism=Saccharomyces cerevisiae, GI6320396, Length=444, Percent_Identity=45.2702702702703, Blast_Score=358, Evalue=1e-100,
Organism=Drosophila melanogaster, GI17737635, Length=439, Percent_Identity=44.6469248291572, Blast_Score=372, Evalue=1e-103,
Organism=Drosophila melanogaster, GI21358125, Length=457, Percent_Identity=44.6389496717724, Blast_Score=336, Evalue=2e-92,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 50114; Mature: 49982

Theoretical pI: Translated: 6.24; Mature: 6.24

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
0.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.4 %Met     (Mature Protein)
0.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSEIRELKKPIREKASIHSHIKGLGLDDNGKAKFIADGLVGQAEAREAAGVVVQLIKQGK
CCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHCC
MSGKGILFVGPPGTGKTALAVAIARELGEDTPFTAINASEIYSTELKKTEILTQLIRKSI
CCCCEEEEECCCCCCHHHHHHHHHHHHCCCCCCEEECHHHHHHHHHHHHHHHHHHHHHHH
GVRIREKRLVYEGVVKDRKIKVARSRLNPYSQAPVEAQITLTTKDDERTLSVGEEIAQQL
CCEEHHHHHHHHHHHCCHHHHHHHHHCCCCCCCCCEEEEEEEECCCCHHHHHHHHHHHHH
VSLGVKKGDVIMIDAQTGQVIVEGKAKGFEGAKTYDIETTKVLEIPTGPVRKEKEITTTL
HHCCCCCCCEEEEECCCCEEEEECCCCCCCCCEEEECCCEEEEECCCCCCCCCCCEEEEE
TLNDLDLNLAARNLAVTAIFSFFTEREINEDVRKEVDRLVKDWINQGRAELVVGVLFIDD
EEECCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCHHEEEEEEEECC
AHTLDLEAFSFLTRALESELAPILILATNRGLTKIRGTDIESPHGIPLDLLDRLLIIPTR
CCCCCHHHHHHHHHHHHHCCCCEEEEEECCCCEEECCCCCCCCCCCCHHHHCCEEEECCC
PYNADEIKEIIKIRADELEIELDPQALEELTKIGVENSLRYSVQLLEPSLIIAQRNNRSI
CCCHHHHHHHHHHHHCCEEEEECHHHHHHHHHCCCCCCCEEEEEEECCEEEEEECCCCCE
IKVEDVVVASKLFSDVKRSVKFVKEYENLLLK
EEEHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SEIRELKKPIREKASIHSHIKGLGLDDNGKAKFIADGLVGQAEAREAAGVVVQLIKQGK
CHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHCC
MSGKGILFVGPPGTGKTALAVAIARELGEDTPFTAINASEIYSTELKKTEILTQLIRKSI
CCCCEEEEECCCCCCHHHHHHHHHHHHCCCCCCEEECHHHHHHHHHHHHHHHHHHHHHHH
GVRIREKRLVYEGVVKDRKIKVARSRLNPYSQAPVEAQITLTTKDDERTLSVGEEIAQQL
CCEEHHHHHHHHHHHCCHHHHHHHHHCCCCCCCCCEEEEEEEECCCCHHHHHHHHHHHHH
VSLGVKKGDVIMIDAQTGQVIVEGKAKGFEGAKTYDIETTKVLEIPTGPVRKEKEITTTL
HHCCCCCCCEEEEECCCCEEEEECCCCCCCCCEEEECCCEEEEECCCCCCCCCCCEEEEE
TLNDLDLNLAARNLAVTAIFSFFTEREINEDVRKEVDRLVKDWINQGRAELVVGVLFIDD
EEECCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCHHEEEEEEEECC
AHTLDLEAFSFLTRALESELAPILILATNRGLTKIRGTDIESPHGIPLDLLDRLLIIPTR
CCCCCHHHHHHHHHHHHHCCCCEEEEEECCCCEEECCCCCCCCCCCCHHHHCCEEEECCC
PYNADEIKEIIKIRADELEIELDPQALEELTKIGVENSLRYSVQLLEPSLIIAQRNNRSI
CCCHHHHHHHHHHHHCCEEEEECHHHHHHHHHCCCCCCCEEEEEEECCEEEEEECCCCCE
IKVEDVVVASKLFSDVKRSVKFVKEYENLLLK
EEEHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA