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The map label for this gene is glnA [H]

Identifier: 227826641

GI number: 227826641

Start: 199925

End: 201202

Strand: Direct

Name: glnA [H]

Synonym: M1425_0232

Alternate gene names: 227826641

Gene position: 199925-201202 (Clockwise)

Preceding gene: 227826640

Following gene: 227826642

Centisome position: 7.66

GC content: 34.19

Gene sequence:

>1278_bases
GTGTCTAAAGAGAATATATTTGATGCTTTAAAATCTGGAAAAATAGATTATGTGAGAGTAGAATTTGTAGATATATTAGG
GAATACCAAAGGTAGGTCTCTAAGGAGAGCGGAATTTGAAAACGTGATAAATAACAACAAAGGAGTTGACTATCCAGAAT
CATTAGCATTGATGGATTACAAGGATAGGCCGATAAAGTCGAAGTATGAGGATATTATTGCTATTCCCGATCTTAACACC
TTCGTTGCAATACCGTATTTAGAAAGAACTGCTAGAGTACTCTCATTTCTAGTCCAACCAGAGGGTTTATCATATCCATA
TTGTAGTAGATCTATACTCAATAAGGCAATAGAGAAGTTAAAGGAAGCAGGGTATACCCTACAAGTTTCGTTTGAACCAA
CATTTTATCTCTTAAATTCTTCCCTAAATCCAGCAGATTATTCCAAAGCTTTCTCGTTGGAGGGACTATTAGAACAACAA
AACTTTCTAAAATTACTTATAAAATATTTGGAAGAAATCGACATCCAAGTTGAAACTATTAATAAACACTATGGTCCAGG
TCAATACGAGGTTAAGCTTTCTCAAAAATCTGTTTTAGAAGCTGCAGACTCCTTGATTTCCAGTAGGGAAGTGATAAGGG
ATACTGCAAAAATGAATAATGTAATTGCTACTTTTATGCCAAAACCATTTAAAGACTACCCTAGTAGTAGTATGGACATT
ACATTAAGCTTGCAAACAACGGATGGAAAAGACATTATGTACGATCCCAATGACGCCAAGGGAATTGGTCTTAGCAAGAT
TGCATACAATTTCATTTCTGGAATATTGGAGCATCTCCCTTCAATACTATCTATCGCTGCACCGACTGTCAATTCATATA
AGAGATTTAAGGAAGTAGTGACTCCAAATATGCCGGGGATAGGCACTGAAAGACATTACATAGTCAGAATTCCAAGTTAT
TATAAGGATACTCGTCAAGTAGAATTCAGATTAGCAGATCCATTAGCGAACCCGTATATTCTATTAGCCAGCATAATATA
TGCAGGCTTAGATGGTATTGAAAGAAATCTTATGGTTAATATAAATGAATATTACGGTAACTTACCACAAACCCTAAAGG
AATCGTTAAGTAGATTAGAGAATGATATATATATGAAGTATAATTTGGGCCAAGATTTAATCACTACTTATATTAATATC
AAAAATATAGAGATAGAAGAATACGAATCAGAAATAACTGAATGGGAAAAAGAGTACTATTTAAAGGCAGGATGGTAA

Upstream 100 bases:

>100_bases
AGTAATTTGACTATATTAAAATTATGACTCATAAAATAAATGCTGAAGCATTCGTGTTAACATTTATTAAATAATTCTAC
AAATAGTTGATGAGATAAAA

Downstream 100 bases:

>100_bases
ATGCTAGCTGCGATTCTAAGAAGTTTCGGTGAGGAATTAAGTCTCGAAGATGTAAGAGAGCCTTCCAATGGAATTATTCT
AAAAGTTCTAGCTACTGGGC

Product: glutamine synthetase

Products: NA

Alternate protein names: GS; Glutamate--ammonia ligase [H]

Number of amino acids: Translated: 425; Mature: 424

Protein sequence:

>425_residues
MSKENIFDALKSGKIDYVRVEFVDILGNTKGRSLRRAEFENVINNNKGVDYPESLALMDYKDRPIKSKYEDIIAIPDLNT
FVAIPYLERTARVLSFLVQPEGLSYPYCSRSILNKAIEKLKEAGYTLQVSFEPTFYLLNSSLNPADYSKAFSLEGLLEQQ
NFLKLLIKYLEEIDIQVETINKHYGPGQYEVKLSQKSVLEAADSLISSREVIRDTAKMNNVIATFMPKPFKDYPSSSMDI
TLSLQTTDGKDIMYDPNDAKGIGLSKIAYNFISGILEHLPSILSIAAPTVNSYKRFKEVVTPNMPGIGTERHYIVRIPSY
YKDTRQVEFRLADPLANPYILLASIIYAGLDGIERNLMVNINEYYGNLPQTLKESLSRLENDIYMKYNLGQDLITTYINI
KNIEIEEYESEITEWEKEYYLKAGW

Sequences:

>Translated_425_residues
MSKENIFDALKSGKIDYVRVEFVDILGNTKGRSLRRAEFENVINNNKGVDYPESLALMDYKDRPIKSKYEDIIAIPDLNT
FVAIPYLERTARVLSFLVQPEGLSYPYCSRSILNKAIEKLKEAGYTLQVSFEPTFYLLNSSLNPADYSKAFSLEGLLEQQ
NFLKLLIKYLEEIDIQVETINKHYGPGQYEVKLSQKSVLEAADSLISSREVIRDTAKMNNVIATFMPKPFKDYPSSSMDI
TLSLQTTDGKDIMYDPNDAKGIGLSKIAYNFISGILEHLPSILSIAAPTVNSYKRFKEVVTPNMPGIGTERHYIVRIPSY
YKDTRQVEFRLADPLANPYILLASIIYAGLDGIERNLMVNINEYYGNLPQTLKESLSRLENDIYMKYNLGQDLITTYINI
KNIEIEEYESEITEWEKEYYLKAGW
>Mature_424_residues
SKENIFDALKSGKIDYVRVEFVDILGNTKGRSLRRAEFENVINNNKGVDYPESLALMDYKDRPIKSKYEDIIAIPDLNTF
VAIPYLERTARVLSFLVQPEGLSYPYCSRSILNKAIEKLKEAGYTLQVSFEPTFYLLNSSLNPADYSKAFSLEGLLEQQN
FLKLLIKYLEEIDIQVETINKHYGPGQYEVKLSQKSVLEAADSLISSREVIRDTAKMNNVIATFMPKPFKDYPSSSMDIT
LSLQTTDGKDIMYDPNDAKGIGLSKIAYNFISGILEHLPSILSIAAPTVNSYKRFKEVVTPNMPGIGTERHYIVRIPSYY
KDTRQVEFRLADPLANPYILLASIIYAGLDGIERNLMVNINEYYGNLPQTLKESLSRLENDIYMKYNLGQDLITTYINIK
NIEIEEYESEITEWEKEYYLKAGW

Specific function: Unknown

COG id: COG0174

COG function: function code E; Glutamine synthetase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glutamine synthetase family [H]

Homologues:

Organism=Homo sapiens, GI221307485, Length=437, Percent_Identity=25.1716247139588, Blast_Score=114, Evalue=1e-25,
Organism=Escherichia coli, GI87081870, Length=443, Percent_Identity=27.0880361173815, Blast_Score=140, Evalue=2e-34,
Organism=Escherichia coli, GI1790301, Length=446, Percent_Identity=25.1121076233184, Blast_Score=97, Evalue=3e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008147
- InterPro:   IPR014746
- InterPro:   IPR008146
- InterPro:   IPR004809 [H]

Pfam domain/function: PF00120 Gln-synt_C; PF03951 Gln-synt_N [H]

EC number: =6.3.1.2 [H]

Molecular weight: Translated: 48651; Mature: 48520

Theoretical pI: Translated: 4.89; Mature: 4.89

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKENIFDALKSGKIDYVRVEFVDILGNTKGRSLRRAEFENVINNNKGVDYPESLALMDY
CCHHHHHHHHHCCCCEEEEEEEEEECCCCCCCHHHHHHHHHHHCCCCCCCCCCCEEEECC
KDRPIKSKYEDIIAIPDLNTFVAIPYLERTARVLSFLVQPEGLSYPYCSRSILNKAIEKL
CCCCCCCCCCCEEECCCCCCEEECHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHH
KEAGYTLQVSFEPTFYLLNSSLNPADYSKAFSLEGLLEQQNFLKLLIKYLEEIDIQVETI
HHCCCEEEEEECCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEEEE
NKHYGPGQYEVKLSQKSVLEAADSLISSREVIRDTAKMNNVIATFMPKPFKDYPSSSMDI
CCCCCCCEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHCCCEECCCCCCCCCCCCCCEE
TLSLQTTDGKDIMYDPNDAKGIGLSKIAYNFISGILEHLPSILSIAAPTVNSYKRFKEVV
EEEEEECCCCEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHH
TPNMPGIGTERHYIVRIPSYYKDTRQVEFRLADPLANPYILLASIIYAGLDGIERNLMVN
CCCCCCCCCCCEEEEECCCHHCCCCEEEEEECCCCCCHHHHHHHHHHHCCCCCCCCEEEE
INEYYGNLPQTLKESLSRLENDIYMKYNLGQDLITTYINIKNIEIEEYESEITEWEKEYY
EHHHCCCCHHHHHHHHHHHCCCEEEEEECCHHHHHHHEEEECCCHHHHHHHHHHHHHHHE
LKAGW
EECCC
>Mature Secondary Structure 
SKENIFDALKSGKIDYVRVEFVDILGNTKGRSLRRAEFENVINNNKGVDYPESLALMDY
CHHHHHHHHHCCCCEEEEEEEEEECCCCCCCHHHHHHHHHHHCCCCCCCCCCCEEEECC
KDRPIKSKYEDIIAIPDLNTFVAIPYLERTARVLSFLVQPEGLSYPYCSRSILNKAIEKL
CCCCCCCCCCCEEECCCCCCEEECHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHH
KEAGYTLQVSFEPTFYLLNSSLNPADYSKAFSLEGLLEQQNFLKLLIKYLEEIDIQVETI
HHCCCEEEEEECCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEEEE
NKHYGPGQYEVKLSQKSVLEAADSLISSREVIRDTAKMNNVIATFMPKPFKDYPSSSMDI
CCCCCCCEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHCCCEECCCCCCCCCCCCCCEE
TLSLQTTDGKDIMYDPNDAKGIGLSKIAYNFISGILEHLPSILSIAAPTVNSYKRFKEVV
EEEEEECCCCEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHH
TPNMPGIGTERHYIVRIPSYYKDTRQVEFRLADPLANPYILLASIIYAGLDGIERNLMVN
CCCCCCCCCCCEEEEECCCHHCCCCEEEEEECCCCCCHHHHHHHHHHHCCCCCCCCEEEE
INEYYGNLPQTLKESLSRLENDIYMKYNLGQDLITTYINIKNIEIEEYESEITEWEKEYY
EHHHCCCCHHHHHHHHHHHCCCEEEEEECCHHHHHHHEEEECCCHHHHHHHHHHHHHHHE
LKAGW
EECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11016950 [H]