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The map label for this gene is mtaD [H]

Identifier: 227826639

GI number: 227826639

Start: 197715

End: 198866

Strand: Direct

Name: mtaD [H]

Synonym: M1425_0230

Alternate gene names: 227826639

Gene position: 197715-198866 (Clockwise)

Preceding gene: 227826631

Following gene: 227826640

Centisome position: 7.58

GC content: 38.37

Gene sequence:

>1152_bases
ATGAAGGTTTTAATAAAAAGTGATTTAGTATTAGGTGCACCTAAGCCTCTCAGAGATGTATATATAGGAATTGATGAAGG
GCAAATAAAGGTTATATCGAAAGAACAGCCAGAAGACTATGATTATGCAGAATACGTGATCGGTGGGAAAAACAGGGTGG
TGGCACCAGGGTTTGTAACTACGCATTCCTTTCTTTACCTATATCCATTTAGGTATAGGATATTTTCGGGTAAGGCAAAC
GCCTTTCAACTAATGTCAACACTTACACCTAATGACATTTACTACTTCTCTTTAATGGGTGCGTATCACTTATTGAAAAC
TGGAGTTACCACAGTAGTCACTTCAGGTCCTAATTTAGATATGACAGCTAGAGCGATTTCGGAAGTTGGACTAAGACCAG
TACTAGCTGTGGGCGTGGATTGTCCAGATTCTAAAGAGGATTGGGAGAGAGAGTTCACAACGTTATATAATAGATGGTCT
AATAAGAACGAGAATAGGGTAATTTTACGTCTTTGTAGCAATGAGTATTCTAAAGAGGTGTTTGAACTCTCACAACAATA
TAACTTCCCCGTTCTCTTAGAGAGATTCGTAAGCTTGGAAAATATTAATGGTAAACCAGTTAACGTGATAGGCTTAGGTG
GAGGGGCTAGGAAGGATCTAGATATTATAAATCAGAAGGGATTTCACTTAGCGTCAACTCCATCCTATGAGGTTTCACAA
TTTCCATTAAGCCAATATAAACCATCAATATCCTTAGATCTATCTCCTACTTTTGATATTAGACATGAAATCTCTACAAC
TATTACCAAGTTAATCTTAACGCCAGAAGAAGCGCTTAACGCCATGACAGTTTGGGGGCAATTACAACTAAAATATAATG
ATAGGGGTGTTTTAGAGAACGGAAAAGTGGCCGATTTAGTTGTATTTGAAGTTAAGGAGCCCCCAACTTTCCCCTTGGAT
TATGAAAGTCCCTACGAGTCCATAGTCTTTAATCTCTCTACCCCAGAGACAGTACTAGTGGGTGGAGAGGCAGTATTAGA
TGGTGGTGTTCCTTTAAATATTGGAATAAAACATATTGAGAAAGCCATAGAGAGGCTTGAAGGCATTGATAAAAAGGTTG
CAAAACCAGCAAGATATATGGAAAAGGATTGA

Upstream 100 bases:

>100_bases
CTACATCTACTTTGTAATCTTGTGTTATCTCACGTTCAATTAAATCTGCGTACATTAAATAACTTTAATTAACATTCTGC
CTAATAGTGTTTTAAGAAAA

Downstream 100 bases:

>100_bases
AATAGTAGGAGATATAGTAATTATTGGGATCCCTTTTAACAAAAGATCAGAAGATCTTATAGAGATAGCAAATGAGATAC
TTTTAACTTTTCCCTATATT

Product: amidohydrolase

Products: NA

Alternate protein names: MTA/SAH deaminase [H]

Number of amino acids: Translated: 383; Mature: 383

Protein sequence:

>383_residues
MKVLIKSDLVLGAPKPLRDVYIGIDEGQIKVISKEQPEDYDYAEYVIGGKNRVVAPGFVTTHSFLYLYPFRYRIFSGKAN
AFQLMSTLTPNDIYYFSLMGAYHLLKTGVTTVVTSGPNLDMTARAISEVGLRPVLAVGVDCPDSKEDWEREFTTLYNRWS
NKNENRVILRLCSNEYSKEVFELSQQYNFPVLLERFVSLENINGKPVNVIGLGGGARKDLDIINQKGFHLASTPSYEVSQ
FPLSQYKPSISLDLSPTFDIRHEISTTITKLILTPEEALNAMTVWGQLQLKYNDRGVLENGKVADLVVFEVKEPPTFPLD
YESPYESIVFNLSTPETVLVGGEAVLDGGVPLNIGIKHIEKAIERLEGIDKKVAKPARYMEKD

Sequences:

>Translated_383_residues
MKVLIKSDLVLGAPKPLRDVYIGIDEGQIKVISKEQPEDYDYAEYVIGGKNRVVAPGFVTTHSFLYLYPFRYRIFSGKAN
AFQLMSTLTPNDIYYFSLMGAYHLLKTGVTTVVTSGPNLDMTARAISEVGLRPVLAVGVDCPDSKEDWEREFTTLYNRWS
NKNENRVILRLCSNEYSKEVFELSQQYNFPVLLERFVSLENINGKPVNVIGLGGGARKDLDIINQKGFHLASTPSYEVSQ
FPLSQYKPSISLDLSPTFDIRHEISTTITKLILTPEEALNAMTVWGQLQLKYNDRGVLENGKVADLVVFEVKEPPTFPLD
YESPYESIVFNLSTPETVLVGGEAVLDGGVPLNIGIKHIEKAIERLEGIDKKVAKPARYMEKD
>Mature_383_residues
MKVLIKSDLVLGAPKPLRDVYIGIDEGQIKVISKEQPEDYDYAEYVIGGKNRVVAPGFVTTHSFLYLYPFRYRIFSGKAN
AFQLMSTLTPNDIYYFSLMGAYHLLKTGVTTVVTSGPNLDMTARAISEVGLRPVLAVGVDCPDSKEDWEREFTTLYNRWS
NKNENRVILRLCSNEYSKEVFELSQQYNFPVLLERFVSLENINGKPVNVIGLGGGARKDLDIINQKGFHLASTPSYEVSQ
FPLSQYKPSISLDLSPTFDIRHEISTTITKLILTPEEALNAMTVWGQLQLKYNDRGVLENGKVADLVVFEVKEPPTFPLD
YESPYESIVFNLSTPETVLVGGEAVLDGGVPLNIGIKHIEKAIERLEGIDKKVAKPARYMEKD

Specific function: Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine [H]

COG id: COG0402

COG function: function code FR; Cytosine deaminase and related metal-dependent hydrolases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the MTA/SAH deaminase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006680
- InterPro:   IPR011059 [H]

Pfam domain/function: PF01979 Amidohydro_1 [H]

EC number: =3.5.4.28 [H]

Molecular weight: Translated: 42990; Mature: 42990

Theoretical pI: Translated: 5.18; Mature: 5.18

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKVLIKSDLVLGAPKPLRDVYIGIDEGQIKVISKEQPEDYDYAEYVIGGKNRVVAPGFVT
CEEEEECCEEECCCCCCCEEEEEECCCEEEEEECCCCCCCCCCCEEECCCCCEECCCCHH
THSFLYLYPFRYRIFSGKANAFQLMSTLTPNDIYYFSLMGAYHLLKTGVTTVVTSGPNLD
HCCEEEEEEEEEEEECCCCHHHHHHHHCCCCCEEEEHHHHHHHHHHCCCEEEEECCCCCC
MTARAISEVGLRPVLAVGVDCPDSKEDWEREFTTLYNRWSNKNENRVILRLCSNEYSKEV
HHHHHHHHCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHCCCCCCEEEEEECCCHHHHHH
FELSQQYNFPVLLERFVSLENINGKPVNVIGLGGGARKDLDIINQKGFHLASTPSYEVSQ
HHHHHHCCCHHHHHHHHHHCCCCCCEEEEEECCCCCCCCHHHHCCCCCEEECCCCCCHHC
FPLSQYKPSISLDLSPTFDIRHEISTTITKLILTPEEALNAMTVWGQLQLKYNDRGVLEN
CCHHHCCCCEEEECCCCCCHHHHHHHHHHHHEECCHHHHCCEEEEEEEEEEECCCCCCCC
GKVADLVVFEVKEPPTFPLDYESPYESIVFNLSTPETVLVGGEAVLDGGVPLNIGIKHIE
CCEEEEEEEEECCCCCCCCCCCCCHHHEEEECCCCCEEEECCCEEECCCCEEECCHHHHH
KAIERLEGIDKKVAKPARYMEKD
HHHHHHHCHHHHHHCHHHHHCCC
>Mature Secondary Structure
MKVLIKSDLVLGAPKPLRDVYIGIDEGQIKVISKEQPEDYDYAEYVIGGKNRVVAPGFVT
CEEEEECCEEECCCCCCCEEEEEECCCEEEEEECCCCCCCCCCCEEECCCCCEECCCCHH
THSFLYLYPFRYRIFSGKANAFQLMSTLTPNDIYYFSLMGAYHLLKTGVTTVVTSGPNLD
HCCEEEEEEEEEEEECCCCHHHHHHHHCCCCCEEEEHHHHHHHHHHCCCEEEEECCCCCC
MTARAISEVGLRPVLAVGVDCPDSKEDWEREFTTLYNRWSNKNENRVILRLCSNEYSKEV
HHHHHHHHCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHCCCCCCEEEEEECCCHHHHHH
FELSQQYNFPVLLERFVSLENINGKPVNVIGLGGGARKDLDIINQKGFHLASTPSYEVSQ
HHHHHHCCCHHHHHHHHHHCCCCCCEEEEEECCCCCCCCHHHHCCCCCEEECCCCCCHHC
FPLSQYKPSISLDLSPTFDIRHEISTTITKLILTPEEALNAMTVWGQLQLKYNDRGVLEN
CCHHHCCCCEEEECCCCCCHHHHHHHHHHHHEECCHHHHCCEEEEEEEEEEECCCCCCCC
GKVADLVVFEVKEPPTFPLDYESPYESIVFNLSTPETVLVGGEAVLDGGVPLNIGIKHIE
CCEEEEEEEEECCCCCCCCCCCCCHHHEEEECCCCCEEEECCCEEECCCCEEECCHHHHH
KAIERLEGIDKKVAKPARYMEKD
HHHHHHHCHHHHHHCHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA