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The map label for this gene is gpt [H]

Identifier: 227826623

GI number: 227826623

Start: 186853

End: 187392

Strand: Direct

Name: gpt [H]

Synonym: M1425_0214

Alternate gene names: 227826623

Gene position: 186853-187392 (Clockwise)

Preceding gene: 227826622

Following gene: 227826625

Centisome position: 7.16

GC content: 35.37

Gene sequence:

>540_bases
ATGGTTGAATATCATATTCCATCATGGGATGAAATAGAAGACGCAGTTTTTTCAATAGGCGAGGCGTTAGTTAAGAATAA
TTATATTCCAGATGTTTTGGTCGCGGTATTAACGGGTGGTATTGTACCGGCTAAACTTCTTTCTGACTTACTAGATTTGA
AAGTAATTAGGTATATAGATATAAAATTCTATCGTAGCGTTGGAAAAACTGAAAGTAGGCCAGTAATCAGGTCCGTATAT
ACTGATTCTTTAGAGGGGAAGAAAGTCCTAGTAATTGATGATGTTGCTGATACTGGCGAAACCCTGGAGGCGGTTAGTAA
TGTTATAACCATGTTTAATCCAGCTAAAGTAATGACTGCAACTTTATACTTAAAACCCTGGTCCAAGAGGGTTCCGGATT
TCTATTACAAACAAATTGATAAGTGGATAATTTTCCCATGGGATAAATGGGATGTTGTTAGGGAAAATAATGATGTTCCC
GTTAACAAAAAGGAGAGATTCTTCGACTTATATAATCAATTATTAAAGATCAGAAAATAG

Upstream 100 bases:

>100_bases
TTCATATTTAATTTTAAGGAAAAAGACGACTATGATAAACTTAAAGGGCATCATGGAGGACTATTGCAAGAGGAATTTGA
GATACCTTTGGTGATCTTGA

Downstream 100 bases:

>100_bases
AAGGTTCTTTATATTCTCCCCAAATATCTCGTAAAACACCGCTGGTCTCCCCTACTGTTGCCCCTGCCCTTATGGCATCA
ATCATGTATGGGAACAAATT

Product: phosphoribosyltransferase

Products: NA

Alternate protein names: Xanthine-guanine phosphoribosyltransferase; XGPRT [H]

Number of amino acids: Translated: 179; Mature: 179

Protein sequence:

>179_residues
MVEYHIPSWDEIEDAVFSIGEALVKNNYIPDVLVAVLTGGIVPAKLLSDLLDLKVIRYIDIKFYRSVGKTESRPVIRSVY
TDSLEGKKVLVIDDVADTGETLEAVSNVITMFNPAKVMTATLYLKPWSKRVPDFYYKQIDKWIIFPWDKWDVVRENNDVP
VNKKERFFDLYNQLLKIRK

Sequences:

>Translated_179_residues
MVEYHIPSWDEIEDAVFSIGEALVKNNYIPDVLVAVLTGGIVPAKLLSDLLDLKVIRYIDIKFYRSVGKTESRPVIRSVY
TDSLEGKKVLVIDDVADTGETLEAVSNVITMFNPAKVMTATLYLKPWSKRVPDFYYKQIDKWIIFPWDKWDVVRENNDVP
VNKKERFFDLYNQLLKIRK
>Mature_179_residues
MVEYHIPSWDEIEDAVFSIGEALVKNNYIPDVLVAVLTGGIVPAKLLSDLLDLKVIRYIDIKFYRSVGKTESRPVIRSVY
TDSLEGKKVLVIDDVADTGETLEAVSNVITMFNPAKVMTATLYLKPWSKRVPDFYYKQIDKWIIFPWDKWDVVRENNDVP
VNKKERFFDLYNQLLKIRK

Specific function: Acts on guanine, xanthine and to a lesser extent hypoxanthine [H]

COG id: COG2236

COG function: function code R; Predicted phosphoribosyltransferases

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the purine/pyrimidine phosphoribosyltransferase family. XGPT subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000836 [H]

Pfam domain/function: PF00156 Pribosyltran [H]

EC number: =2.4.2.22 [H]

Molecular weight: Translated: 20775; Mature: 20775

Theoretical pI: Translated: 6.01; Mature: 6.01

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVEYHIPSWDEIEDAVFSIGEALVKNNYIPDVLVAVLTGGIVPAKLLSDLLDLKVIRYID
CCCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHH
IKFYRSVGKTESRPVIRSVYTDSLEGKKVLVIDDVADTGETLEAVSNVITMFNPAKVMTA
HHHHHHHCCCCCCCHHHHHHHCCCCCCEEEEEECCCCCHHHHHHHHHHHHHCCCHHHHEE
TLYLKPWSKRVPDFYYKQIDKWIIFPWDKWDVVRENNDVPVNKKERFFDLYNQLLKIRK
HEEECCHHHCCCHHHHHHHCCEEECCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MVEYHIPSWDEIEDAVFSIGEALVKNNYIPDVLVAVLTGGIVPAKLLSDLLDLKVIRYID
CCCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHH
IKFYRSVGKTESRPVIRSVYTDSLEGKKVLVIDDVADTGETLEAVSNVITMFNPAKVMTA
HHHHHHHCCCCCCCHHHHHHHCCCCCCEEEEEECCCCCHHHHHHHHHHHHHCCCHHHHEE
TLYLKPWSKRVPDFYYKQIDKWIIFPWDKWDVVRENNDVPVNKKERFFDLYNQLLKIRK
HEEECCHHHCCCHHHHHHHCCEEECCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA