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The map label for this gene is 227826416

Identifier: 227826416

GI number: 227826416

Start: 3277

End: 3576

Strand: Direct

Name: 227826416

Synonym: M1425_0005

Alternate gene names: NA

Gene position: 3277-3576 (Clockwise)

Preceding gene: 227826415

Following gene: 227826423

Centisome position: 0.13

GC content: 30.33

Gene sequence:

>300_bases
ATGAGTGGAATTTCCTCGAAGGGACTAGAGGAACTTAAAAATAACGGTTGGTTAATATTAGAGGATGGGAAGAAGATTAA
GAAGGAATTTAAGTTTAAGGATTTTAAGCAATCAATAGATTTCTTGAAAGATATACAACCATCAGCTGATGCTTTAGATC
ATCATCCTGATGTTTGTATCTATTATAATAGAGTAATAGTGGAGTTAACAACCCATGATATGGGAGGATTAACAGATCTT
GACTATAAATTGGCTATAAAAATTGATGAACTTTATAAAATGAAAACTAGTAATTTATAG

Upstream 100 bases:

>100_bases
AATTCCTCTAGTTATAGCTTTAGTAAAGAAATTCTTAGCAGAAATTAAGTGATTCTTTATAACAAGCTATTTTTTTAACT
CTCGTTTACTTATATTTTTT

Downstream 100 bases:

>100_bases
TAAGGATTGACGTGTAAAATGACAATAGCGTTTTTGTACATTAATCCTTGCACTATTTATCAAAATTTTAAGAAGTTAGA
AAGAACTCAATACGTTCTCT

Product: transcriptional coactivator/pterin dehydratase

Products: NA

Alternate protein names: PHS; 4-alpha-hydroxy-tetrahydropterin dehydratase; Pterin carbinolamine dehydratase; PCD

Number of amino acids: Translated: 99; Mature: 98

Protein sequence:

>99_residues
MSGISSKGLEELKNNGWLILEDGKKIKKEFKFKDFKQSIDFLKDIQPSADALDHHPDVCIYYNRVIVELTTHDMGGLTDL
DYKLAIKIDELYKMKTSNL

Sequences:

>Translated_99_residues
MSGISSKGLEELKNNGWLILEDGKKIKKEFKFKDFKQSIDFLKDIQPSADALDHHPDVCIYYNRVIVELTTHDMGGLTDL
DYKLAIKIDELYKMKTSNL
>Mature_98_residues
SGISSKGLEELKNNGWLILEDGKKIKKEFKFKDFKQSIDFLKDIQPSADALDHHPDVCIYYNRVIVELTTHDMGGLTDLD
YKLAIKIDELYKMKTSNL

Specific function: Unknown

COG id: COG2154

COG function: function code H; Pterin-4a-carbinolamine dehydratase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the pterin-4-alpha-carbinolamine dehydratase family

Homologues:

Organism=Homo sapiens, GI4557831, Length=83, Percent_Identity=38.5542168674699, Blast_Score=66, Evalue=5e-12,
Organism=Homo sapiens, GI134133240, Length=75, Percent_Identity=41.3333333333333, Blast_Score=66, Evalue=6e-12,
Organism=Caenorhabditis elegans, GI115533705, Length=85, Percent_Identity=42.3529411764706, Blast_Score=75, Evalue=5e-15,
Organism=Drosophila melanogaster, GI45549100, Length=81, Percent_Identity=37.037037037037, Blast_Score=67, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): PHS_SULIA (C3MZU9)

Other databases:

- EMBL:   CP001401
- RefSeq:   YP_002842079.1
- GeneID:   7812065
- GenomeReviews:   CP001401_GR
- KEGG:   sim:M1627_0005
- OMA:   TVEIYTH
- ProtClustDB:   CLSK2484518
- HAMAP:   MF_00434
- InterPro:   IPR001533
- Gene3D:   G3DSA:3.30.1360.20
- PANTHER:   PTHR12599

Pfam domain/function: PF01329 Pterin_4a; SSF55248 Trans_pterinDh

EC number: =4.2.1.96

Molecular weight: Translated: 11408; Mature: 11277

Theoretical pI: Translated: 6.25; Mature: 6.25

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSGISSKGLEELKNNGWLILEDGKKIKKEFKFKDFKQSIDFLKDIQPSADALDHHPDVCI
CCCCCCCCHHHHHCCCEEEEECCHHHHHHCCHHHHHHHHHHHHCCCCCCCHHCCCCCEEE
YYNRVIVELTTHDMGGLTDLDYKLAIKIDELYKMKTSNL
EEEEEEEEEECCCCCCCCCCCEEEEEEHHHHHHHHCCCC
>Mature Secondary Structure 
SGISSKGLEELKNNGWLILEDGKKIKKEFKFKDFKQSIDFLKDIQPSADALDHHPDVCI
CCCCCCCHHHHHCCCEEEEECCHHHHHHCCHHHHHHHHHHHHCCCCCCCHHCCCCCEEE
YYNRVIVELTTHDMGGLTDLDYKLAIKIDELYKMKTSNL
EEEEEEEEEECCCCCCCCCCCEEEEEEHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA