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The map label for this gene is cdc6-3 [H]

Identifier: 227826413

GI number: 227826413

Start: 837

End: 2024

Strand: Direct

Name: cdc6-3 [H]

Synonym: M1425_0002

Alternate gene names: 227826413

Gene position: 837-2024 (Clockwise)

Preceding gene: 227826412

Following gene: 227826414

Centisome position: 0.03

GC content: 36.36

Gene sequence:

>1188_bases
GTGAATGTGATAAGGGAAACATTGAAAGGTGGTAAAGGTGAAGTTATAAAAAACCCTAAGGTCTTTATTGATCCGTTATC
TGTATTTAAGGAGATTCCGTTCAGAGAGGATATACTAAGGGATGCTGCAATAGCTATTAGGTATTTTGTTAAGAATGAGG
TCAAGTTTTCGAACTTGTTTCTTGGATTAACCGGTACTGGGAAGACTTTCGTAAGTAAATACATCTATAACGAGATTGAG
GAGGTTAAGAATGAGGATGAGGAATATAAGGATGTAAAACAAGCTTATGTTAATTGTAGAGAAGTTGGTGGAACACCACA
AGCAGTATTATCATCCTTAGCTGGTAAGCTGACTGGTTTTTCAGTGCCTAAGCATGGTATTAATCTAGGTGAGTACATTG
ATAAGATAAAGAATGGTACTAGGAACATAAAGGCCATAATATATCTTGACGAGGTTGACACATTAGTTAAGAGGAGAGGG
GGAGATATAGTACTTTATCAACTGCTAAGGTCAGATGCTAATATATCAGTTATTATGATTAGTAATGACATAAATGTTCG
TGACTATATGGAGCCTAGAGTTTTATCATCCTTAGGTCCTTCAGTTATCTTTAAACCTTACGACGCAGAACAACTGAAAT
TTATCCTTTCAAAGTACGCAGAATACGGTTTAATAAAAGGTACCTATGATGGTGATATACTGGGTTATATTGCAGCTATC
TCTGCTAAAGAACATGGTGATGCAAGAAAGGCAGTCAATTTGCTTTTCAGAGCAGCTCAACTAGCTTCTGGTGGGGGGAT
GATTAAAAAGGAGCACGTAGATAAGGCGATCGTAGATTATGAACAAGAGAGGCTTATAGAGGCCGTAAAAGCCCTTCCTT
TTCACTATAAATTAGCTTTAAGAAGTCTAATAGAGTCAGAAGATGTGATGTCTGCTCACAAAATGTATACTGATCTTTGT
AATAAGTTCAAACAAAAGCCTTTATCGTATAGAAGATTTTCAGACATAATATCGGAGTTGGATATGTTTGGGATAGTTAA
GATAAGGATAGTTAATAGGGGTAGAGCTGGTGGAGTTAAGAAGTATGCTTTAGTGGAAGATAAGGAGAAGGTGTTAAGGG
CACTTAATGAGACTTTTGAAGATAGTATTGGTATTGGTGAATTTGTTGATGATGTGGGAGAAAATTAA

Upstream 100 bases:

>100_bases
TGGTAAAAACTTCAATTTTGAAGTAATATTGATATAACCTGTGGTCTAGATATTACCAATACAGTCATAGGAAACAGGTT
TAACAGTAGAAACATTAGAA

Downstream 100 bases:

>100_bases
GAGGCTAGAAGAAAGATTGTATGAACTAAGAAAGGAAATTGAGGAAGTTGAAAAAGAATTAGAAGAATTACCAAGCGGAC
ATCTTGAGGTAAAGACGATT

Product: orc1/cdc6 family replication initiation protein

Products: NA

Alternate protein names: CDC6 homolog 3 [H]

Number of amino acids: Translated: 395; Mature: 395

Protein sequence:

>395_residues
MNVIRETLKGGKGEVIKNPKVFIDPLSVFKEIPFREDILRDAAIAIRYFVKNEVKFSNLFLGLTGTGKTFVSKYIYNEIE
EVKNEDEEYKDVKQAYVNCREVGGTPQAVLSSLAGKLTGFSVPKHGINLGEYIDKIKNGTRNIKAIIYLDEVDTLVKRRG
GDIVLYQLLRSDANISVIMISNDINVRDYMEPRVLSSLGPSVIFKPYDAEQLKFILSKYAEYGLIKGTYDGDILGYIAAI
SAKEHGDARKAVNLLFRAAQLASGGGMIKKEHVDKAIVDYEQERLIEAVKALPFHYKLALRSLIESEDVMSAHKMYTDLC
NKFKQKPLSYRRFSDIISELDMFGIVKIRIVNRGRAGGVKKYALVEDKEKVLRALNETFEDSIGIGEFVDDVGEN

Sequences:

>Translated_395_residues
MNVIRETLKGGKGEVIKNPKVFIDPLSVFKEIPFREDILRDAAIAIRYFVKNEVKFSNLFLGLTGTGKTFVSKYIYNEIE
EVKNEDEEYKDVKQAYVNCREVGGTPQAVLSSLAGKLTGFSVPKHGINLGEYIDKIKNGTRNIKAIIYLDEVDTLVKRRG
GDIVLYQLLRSDANISVIMISNDINVRDYMEPRVLSSLGPSVIFKPYDAEQLKFILSKYAEYGLIKGTYDGDILGYIAAI
SAKEHGDARKAVNLLFRAAQLASGGGMIKKEHVDKAIVDYEQERLIEAVKALPFHYKLALRSLIESEDVMSAHKMYTDLC
NKFKQKPLSYRRFSDIISELDMFGIVKIRIVNRGRAGGVKKYALVEDKEKVLRALNETFEDSIGIGEFVDDVGEN
>Mature_395_residues
MNVIRETLKGGKGEVIKNPKVFIDPLSVFKEIPFREDILRDAAIAIRYFVKNEVKFSNLFLGLTGTGKTFVSKYIYNEIE
EVKNEDEEYKDVKQAYVNCREVGGTPQAVLSSLAGKLTGFSVPKHGINLGEYIDKIKNGTRNIKAIIYLDEVDTLVKRRG
GDIVLYQLLRSDANISVIMISNDINVRDYMEPRVLSSLGPSVIFKPYDAEQLKFILSKYAEYGLIKGTYDGDILGYIAAI
SAKEHGDARKAVNLLFRAAQLASGGGMIKKEHVDKAIVDYEQERLIEAVKALPFHYKLALRSLIESEDVMSAHKMYTDLC
NKFKQKPLSYRRFSDIISELDMFGIVKIRIVNRGRAGGVKKYALVEDKEKVLRALNETFEDSIGIGEFVDDVGEN

Specific function: Might be involved in the initiation of DNA replication [H]

COG id: COG1474

COG function: function code LO; Cdc6-related protein, AAA superfamily ATPase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CDC6/cdc18 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR003959
- InterPro:   IPR015163
- InterPro:   IPR014277
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00004 AAA; PF09079 Cdc6_C [H]

EC number: NA

Molecular weight: Translated: 44463; Mature: 44463

Theoretical pI: Translated: 8.49; Mature: 8.49

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNVIRETLKGGKGEVIKNPKVFIDPLSVFKEIPFREDILRDAAIAIRYFVKNEVKFSNLF
CCHHHHHHCCCCCCEECCCCEEECHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCEEEEEE
LGLTGTGKTFVSKYIYNEIEEVKNEDEEYKDVKQAYVNCREVGGTPQAVLSSLAGKLTGF
EEECCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCC
SVPKHGINLGEYIDKIKNGTRNIKAIIYLDEVDTLVKRRGGDIVLYQLLRSDANISVIMI
CCCCCCCCHHHHHHHHHCCCCCEEEEEEEHHHHHHHHHCCCCHHHHHHHHCCCCEEEEEE
SNDINVRDYMEPRVLSSLGPSVIFKPYDAEQLKFILSKYAEYGLIKGTYDGDILGYIAAI
ECCCCHHHHCCHHHHHHCCCCEEECCCCHHHHHHHHHHHHHCCCEECCCCCHHHHHHHHH
SAKEHGDARKAVNLLFRAAQLASGGGMIKKEHVDKAIVDYEQERLIEAVKALPFHYKLAL
HCHHCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHH
RSLIESEDVMSAHKMYTDLCNKFKQKPLSYRRFSDIISELDMFGIVKIRIVNRGRAGGVK
HHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCEEEEEEEECCCCCCCC
KYALVEDKEKVLRALNETFEDSIGIGEFVDDVGEN
HHHHHCCHHHHHHHHHHHHHHCCCHHHHHHHHCCC
>Mature Secondary Structure
MNVIRETLKGGKGEVIKNPKVFIDPLSVFKEIPFREDILRDAAIAIRYFVKNEVKFSNLF
CCHHHHHHCCCCCCEECCCCEEECHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCEEEEEE
LGLTGTGKTFVSKYIYNEIEEVKNEDEEYKDVKQAYVNCREVGGTPQAVLSSLAGKLTGF
EEECCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCC
SVPKHGINLGEYIDKIKNGTRNIKAIIYLDEVDTLVKRRGGDIVLYQLLRSDANISVIMI
CCCCCCCCHHHHHHHHHCCCCCEEEEEEEHHHHHHHHHCCCCHHHHHHHHCCCCEEEEEE
SNDINVRDYMEPRVLSSLGPSVIFKPYDAEQLKFILSKYAEYGLIKGTYDGDILGYIAAI
ECCCCHHHHCCHHHHHHCCCCEEECCCCHHHHHHHHHHHHHCCCEECCCCCHHHHHHHHH
SAKEHGDARKAVNLLFRAAQLASGGGMIKKEHVDKAIVDYEQERLIEAVKALPFHYKLAL
HCHHCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHH
RSLIESEDVMSAHKMYTDLCNKFKQKPLSYRRFSDIISELDMFGIVKIRIVNRGRAGGVK
HHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCEEEEEEEECCCCCCCC
KYALVEDKEKVLRALNETFEDSIGIGEFVDDVGEN
HHHHHCCHHHHHHHHHHHHHHCCCHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11427726 [H]