| Definition | Bacillus anthracis str. CDC 684, complete genome. |
|---|---|
| Accession | NC_012581 |
| Length | 5,230,115 |
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The map label for this gene is secA2 [H]
Identifier: 227817947
GI number: 227817947
Start: 4910803
End: 4913310
Strand: Reverse
Name: secA2 [H]
Synonym: BAMEG_5472
Alternate gene names: 227817947
Gene position: 4913310-4910803 (Counterclockwise)
Preceding gene: 227817948
Following gene: 227817945
Centisome position: 93.94
GC content: 39.39
Gene sequence:
>2508_bases ATGATCGGTATTTTAAAAAAGGTGTTTGATGTAAATCAACGCCAAATTAAACGTATGCAGAAAACAGTTGAGCAAATTGA TGCATTAGAGTCATCTATTAAGCCACTAACTGATGAACAATTAAAAGGGAAGACGCTTGAATTTAAAGAACGTCTAACAA AAGGTGAAACAGTAGATGATCTACTACCTGAAGCTTTTGCGGTTGTTCGTGAAGCTGCGACTCGTGTTCTTGGAATGCGT CCGTATGGCGTACAGTTAATGGGTGGTATTGCCTTACATGAAGGGAATATCTCTGAGATGAAAACGGGTGAAGGTAAAAC GTTAACATCTACATTACCTGTATATTTAAATGCTTTAACAGGAAAAGGTGTTCACGTCGTTACAGTCAATGAATACTTAG CGCAACGTGATGCGAACGAAATGGGACAACTTCATGAGTTCCTAGGCTTAACAGTAGGAATTAATTTAAACAGTATGTCA CGCGAAGAGAAACAAGAGGCTTATGCTGCTGATATTACGTATAGCACAAATAATGAGCTTGGATTCGATTACTTACGTGA CAACATGGTTTTATATAAAGAGCAGTGCGTTCAACGCCCGCTTCACTTTGCTATTATCGATGAAGTCGATTCTATCTTAG TCGATGAAGCGCGTACGCCACTTATTATTTCTGGACAAGCTCAAAAATCAACAGAGCTGTACATGTTTGCAAATGCATTC GTTCGTACGTTAGAAAATGAAAAAGATTATTCATTTGATGTGAAGACGAAAAATGTAATGTTAACAGAAGATGGTATTAC GAAAGCGGAGAAAGCTTTCCATATTGAAAACTTATTTGATTTAAAACATGTAGCACTTCTTCACCATATTAATCAAGCAC TTCGTGCGCACGTTGTAATGCACCGTGATACAGATTATGTTGTACAAGAAGGCGAAATCGTAATTGTAGACCAATTTACT GGTCGTCTTATGAAAGGTCGTCGTTATAGTGAAGGTTTACACCAAGCTATCGAGGCAAAAGAAGGCGTAGAAATTCAAAA TGAAAGTATGACGCTTGCGACAATTACGTTCCAGAACTACTTCCGTATGTACGAAAAGTTATCTGGTATGACTGGTACAG CGAAAACAGAGGAAGAGGAATTCCGTAACATTTACAATATGAACGTTATTGTAATTCCAACGAACAAACCGATTATTCGT GATGACCGTGCGGATTTAATCTTCAAATCAATGAAAGGTAAATTTAATGCTGTTGTTGAGGATATTGTAAATCGTCATAA ACAAGGGCAACCTGTTCTTGTCGGTACAGTGGCGATTGAAACGTCAGAGCTTATTTCAAAAATGTTAACGCGTAAAGGCG TACGTCATAACATCTTAAATGCGAAAAACCATGCGCGTGAAGCGGATATCATTGCAGAAGCTGGTATGAAAGGTGCTGTA ACGATCGCGACGAATATGGCAGGGCGTGGTACTGATATTAAGCTTGGAGACGATATTAAAAACATTGGTTTAGCAGTTAT CGGTACAGAGCGTCACGAAAGTCGTCGTATTGATAATCAGTTACGTGGTCGTGCTGGTCGTCAAGGGGACCCAGGTGTTA CGCAGTTCTACTTATCAATGGAAGATGAACTAATGCGCCGCTTCGGTTCTGATAATATGAAAGCAATGATGGATCGCCTT GGTATGGATGATTCTCAGCCAATCGAAAGTAAAATGGTTTCTCGTGCAGTAGAATCTGCGCAAAAACGTGTAGAAGGAAA TAACTATGATGCACGTAAGCAGTTACTACAATATGATGATGTACTTCGTCAGCAACGTGAAGTTATTTACAAACAGCGTC AAGAGGTAATGGAGTCTGAGAACTTACGCGGTATTATTGAAGGTATGATGAAATCTACAGTAGAGCGTGCGGTTGCGCTT CATACACAAGAGGAAATTGAAGAAGATTGGAACATTAAAGGTCTTGTTGACTACTTAAATACAAACCTTCTGCAAGAAGG AGATGTGAAAGAAGAAGAATTACGTCGCCTTGCTCCAGAGGAAATGAGCGAACCAATTATCGCGAAATTAATAGAGCGTT ACAATGACAAAGAAAAGCTTATGCCAGAAGAGCAAATGCGTGAGTTCGAAAAAGTTGTTGTATTCCGTGTTGTAGATACG AAATGGACAGAGCATATCGATGCGATGGATCACCTTCGTGAAGGTATTCATTTACGTGCTTACGGTCAAATTGATCCACT TCGTGAGTATCAAATGGAAGGATTCGCAATGTTCGAGTCAATGATTGCTTCTATTGAAGAGGAAATTTCTCGTTACATTA TGAAAGCTGAAATTGAACAAAACTTAGAGCGTCAAGAAGTTGTTCAAGGTGAAGCTGTTCACCCATCTAGTGATGGCGAA GAAGCGAAGAAAAAACCAGTTGTAAAAGGTGACCAAGTCGGCCGCAACGATTTATGTAAATGTGGTAGCGGTAAAAAATA TAAAAACTGCTGTGGTATCGGGAAGTAA
Upstream 100 bases:
>100_bases GGCATAACATACATTTGATTTTTATAACGACTGATTGTAATAGAGAAAAAGAAAAAACAATCGGAAGTTTTATTTTAATA AAAAGAGGAGCGTATTTCCT
Downstream 100 bases:
>100_bases TACAGGGCGCTAGCTTTGGCTACTTTGCAAACTTTTACATCAAAAATGTATAATTAAGAAGGATTAAACTCTCTCCGTCA TAAGTGGAGAGAGTTTCCCT
Product: preprotein translocase subunit SecA
Products: NA
Alternate protein names: NA
Number of amino acids: Translated: 835; Mature: 835
Protein sequence:
>835_residues MIGILKKVFDVNQRQIKRMQKTVEQIDALESSIKPLTDEQLKGKTLEFKERLTKGETVDDLLPEAFAVVREAATRVLGMR PYGVQLMGGIALHEGNISEMKTGEGKTLTSTLPVYLNALTGKGVHVVTVNEYLAQRDANEMGQLHEFLGLTVGINLNSMS REEKQEAYAADITYSTNNELGFDYLRDNMVLYKEQCVQRPLHFAIIDEVDSILVDEARTPLIISGQAQKSTELYMFANAF VRTLENEKDYSFDVKTKNVMLTEDGITKAEKAFHIENLFDLKHVALLHHINQALRAHVVMHRDTDYVVQEGEIVIVDQFT GRLMKGRRYSEGLHQAIEAKEGVEIQNESMTLATITFQNYFRMYEKLSGMTGTAKTEEEEFRNIYNMNVIVIPTNKPIIR DDRADLIFKSMKGKFNAVVEDIVNRHKQGQPVLVGTVAIETSELISKMLTRKGVRHNILNAKNHAREADIIAEAGMKGAV TIATNMAGRGTDIKLGDDIKNIGLAVIGTERHESRRIDNQLRGRAGRQGDPGVTQFYLSMEDELMRRFGSDNMKAMMDRL GMDDSQPIESKMVSRAVESAQKRVEGNNYDARKQLLQYDDVLRQQREVIYKQRQEVMESENLRGIIEGMMKSTVERAVAL HTQEEIEEDWNIKGLVDYLNTNLLQEGDVKEEELRRLAPEEMSEPIIAKLIERYNDKEKLMPEEQMREFEKVVVFRVVDT KWTEHIDAMDHLREGIHLRAYGQIDPLREYQMEGFAMFESMIASIEEEISRYIMKAEIEQNLERQEVVQGEAVHPSSDGE EAKKKPVVKGDQVGRNDLCKCGSGKKYKNCCGIGK
Sequences:
>Translated_835_residues MIGILKKVFDVNQRQIKRMQKTVEQIDALESSIKPLTDEQLKGKTLEFKERLTKGETVDDLLPEAFAVVREAATRVLGMR PYGVQLMGGIALHEGNISEMKTGEGKTLTSTLPVYLNALTGKGVHVVTVNEYLAQRDANEMGQLHEFLGLTVGINLNSMS REEKQEAYAADITYSTNNELGFDYLRDNMVLYKEQCVQRPLHFAIIDEVDSILVDEARTPLIISGQAQKSTELYMFANAF VRTLENEKDYSFDVKTKNVMLTEDGITKAEKAFHIENLFDLKHVALLHHINQALRAHVVMHRDTDYVVQEGEIVIVDQFT GRLMKGRRYSEGLHQAIEAKEGVEIQNESMTLATITFQNYFRMYEKLSGMTGTAKTEEEEFRNIYNMNVIVIPTNKPIIR DDRADLIFKSMKGKFNAVVEDIVNRHKQGQPVLVGTVAIETSELISKMLTRKGVRHNILNAKNHAREADIIAEAGMKGAV TIATNMAGRGTDIKLGDDIKNIGLAVIGTERHESRRIDNQLRGRAGRQGDPGVTQFYLSMEDELMRRFGSDNMKAMMDRL GMDDSQPIESKMVSRAVESAQKRVEGNNYDARKQLLQYDDVLRQQREVIYKQRQEVMESENLRGIIEGMMKSTVERAVAL HTQEEIEEDWNIKGLVDYLNTNLLQEGDVKEEELRRLAPEEMSEPIIAKLIERYNDKEKLMPEEQMREFEKVVVFRVVDT KWTEHIDAMDHLREGIHLRAYGQIDPLREYQMEGFAMFESMIASIEEEISRYIMKAEIEQNLERQEVVQGEAVHPSSDGE EAKKKPVVKGDQVGRNDLCKCGSGKKYKNCCGIGK >Mature_835_residues MIGILKKVFDVNQRQIKRMQKTVEQIDALESSIKPLTDEQLKGKTLEFKERLTKGETVDDLLPEAFAVVREAATRVLGMR PYGVQLMGGIALHEGNISEMKTGEGKTLTSTLPVYLNALTGKGVHVVTVNEYLAQRDANEMGQLHEFLGLTVGINLNSMS REEKQEAYAADITYSTNNELGFDYLRDNMVLYKEQCVQRPLHFAIIDEVDSILVDEARTPLIISGQAQKSTELYMFANAF VRTLENEKDYSFDVKTKNVMLTEDGITKAEKAFHIENLFDLKHVALLHHINQALRAHVVMHRDTDYVVQEGEIVIVDQFT GRLMKGRRYSEGLHQAIEAKEGVEIQNESMTLATITFQNYFRMYEKLSGMTGTAKTEEEEFRNIYNMNVIVIPTNKPIIR DDRADLIFKSMKGKFNAVVEDIVNRHKQGQPVLVGTVAIETSELISKMLTRKGVRHNILNAKNHAREADIIAEAGMKGAV TIATNMAGRGTDIKLGDDIKNIGLAVIGTERHESRRIDNQLRGRAGRQGDPGVTQFYLSMEDELMRRFGSDNMKAMMDRL GMDDSQPIESKMVSRAVESAQKRVEGNNYDARKQLLQYDDVLRQQREVIYKQRQEVMESENLRGIIEGMMKSTVERAVAL HTQEEIEEDWNIKGLVDYLNTNLLQEGDVKEEELRRLAPEEMSEPIIAKLIERYNDKEKLMPEEQMREFEKVVVFRVVDT KWTEHIDAMDHLREGIHLRAYGQIDPLREYQMEGFAMFESMIASIEEEISRYIMKAEIEQNLERQEVVQGEAVHPSSDGE EAKKKPVVKGDQVGRNDLCKCGSGKKYKNCCGIGK
Specific function: Part of the Sec protein translocase complex. Interacts with the secYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular mo
COG id: COG0653
COG function: function code U; Preprotein translocase subunit SecA (ATPase, RNA helicase)
Gene ontology:
Cell location: Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm (By similarity). Note=Distribution is 50-50 (By similarity) [H]
Metaboloic importance: Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the secA family [H]
Homologues:
Organism=Escherichia coli, GI1786287, Length=903, Percent_Identity=50.8305647840532, Blast_Score=871, Evalue=0.0,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR001650 - InterPro: IPR004027 - InterPro: IPR000185 - InterPro: IPR020937 - InterPro: IPR011115 - InterPro: IPR014018 - InterPro: IPR011130 - InterPro: IPR011116 [H]
Pfam domain/function: PF00271 Helicase_C; PF02810 SEC-C; PF07517 SecA_DEAD; PF01043 SecA_PP_bind; PF07516 SecA_SW [H]
EC number: NA
Molecular weight: Translated: 95077; Mature: 95077
Theoretical pI: Translated: 5.42; Mature: 5.42
Prosite motif: PS01312 SECA
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.6 %Cys (Translated Protein) 4.6 %Met (Translated Protein) 5.1 %Cys+Met (Translated Protein) 0.6 %Cys (Mature Protein) 4.6 %Met (Mature Protein) 5.1 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MIGILKKVFDVNQRQIKRMQKTVEQIDALESSIKPLTDEQLKGKTLEFKERLTKGETVDD CCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHCCCCHHHHHHHCCCCCHHH LLPEAFAVVREAATRVLGMRPYGVQLMGGIALHEGNISEMKTGEGKTLTSTLPVYLNALT HHHHHHHHHHHHHHHHHCCCCCCHHEECCEEEECCCHHHCCCCCCCEEHHHHHHHHHHCC GKGVHVVTVNEYLAQRDANEMGQLHEFLGLTVGINLNSMSREEKQEAYAADITYSTNNEL CCCEEEEEHHHHHHHCCHHHHHHHHHHHCEEEEECCCCCCHHHHHHHHHEEEEECCCCCC GFDYLRDNMVLYKEQCVQRPLHFAIIDEVDSILVDEARTPLIISGQAQKSTELYMFANAF CHHHHHCCHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCEEEECCCCCCCHHHHHHHHH VRTLENEKDYSFDVKTKNVMLTEDGITKAEKAFHIENLFDLKHVALLHHINQALRAHVVM HHHHCCCCCCEEEEEECEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHE HRDTDYVVQEGEIVIVDQFTGRLMKGRRYSEGLHQAIEAKEGVEIQNESMTLATITFQNY ECCCCCEEECCCEEEEECHHHHHHCCCHHHHHHHHHHHHHCCCEEECCCEEEEEEHHHHH FRMYEKLSGMTGTAKTEEEEFRNIYNMNVIVIPTNKPIIRDDRADLIFKSMKGKFNAVVE HHHHHHHCCCCCCCCCCHHHHHHHHCCEEEEEECCCCCCCCCHHHHHHHHHCCHHHHHHH DIVNRHKQGQPVLVGTVAIETSELISKMLTRKGVRHNILNAKNHAREADIIAEAGMKGAV HHHHHCCCCCCEEEEEEEECHHHHHHHHHHHCCHHHHHHCCHHHHHHHHHHHHCCCCCEE TIATNMAGRGTDIKLGDDIKNIGLAVIGTERHESRRIDNQLRGRAGRQGDPGVTQFYLSM EEEECCCCCCCCEEECCCHHHCCEEEEECCHHHHHHHHHHHHCCCCCCCCCCHHEEEECH EDELMRRFGSDNMKAMMDRLGMDDSQPIESKMVSRAVESAQKRVEGNNYDARKQLLQYDD HHHHHHHHCCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHH VLRQQREVIYKQRQEVMESENLRGIIEGMMKSTVERAVALHTQEEIEEDWNIKGLVDYLN HHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHH TNLLQEGDVKEEELRRLAPEEMSEPIIAKLIERYNDKEKLMPEEQMREFEKVVVFRVVDT HHHCCCCCCCHHHHHHCCHHHHCCHHHHHHHHHHCCHHHCCCHHHHHHHHHHHHHHHHCC KWTEHIDAMDHLREGIHLRAYGQIDPLREYQMEGFAMFESMIASIEEEISRYIMKAEIEQ HHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH NLERQEVVQGEAVHPSSDGEEAKKKPVVKGDQVGRNDLCKCGSGKKYKNCCGIGK CCHHHHHHCCCCCCCCCCCHHHHHCCCCCCCCCCCHHHHCCCCCCCHHHHCCCCC >Mature Secondary Structure MIGILKKVFDVNQRQIKRMQKTVEQIDALESSIKPLTDEQLKGKTLEFKERLTKGETVDD CCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHCCCCHHHHHHHCCCCCHHH LLPEAFAVVREAATRVLGMRPYGVQLMGGIALHEGNISEMKTGEGKTLTSTLPVYLNALT HHHHHHHHHHHHHHHHHCCCCCCHHEECCEEEECCCHHHCCCCCCCEEHHHHHHHHHHCC GKGVHVVTVNEYLAQRDANEMGQLHEFLGLTVGINLNSMSREEKQEAYAADITYSTNNEL CCCEEEEEHHHHHHHCCHHHHHHHHHHHCEEEEECCCCCCHHHHHHHHHEEEEECCCCCC GFDYLRDNMVLYKEQCVQRPLHFAIIDEVDSILVDEARTPLIISGQAQKSTELYMFANAF CHHHHHCCHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCEEEECCCCCCCHHHHHHHHH VRTLENEKDYSFDVKTKNVMLTEDGITKAEKAFHIENLFDLKHVALLHHINQALRAHVVM HHHHCCCCCCEEEEEECEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHE HRDTDYVVQEGEIVIVDQFTGRLMKGRRYSEGLHQAIEAKEGVEIQNESMTLATITFQNY ECCCCCEEECCCEEEEECHHHHHHCCCHHHHHHHHHHHHHCCCEEECCCEEEEEEHHHHH FRMYEKLSGMTGTAKTEEEEFRNIYNMNVIVIPTNKPIIRDDRADLIFKSMKGKFNAVVE HHHHHHHCCCCCCCCCCHHHHHHHHCCEEEEEECCCCCCCCCHHHHHHHHHCCHHHHHHH DIVNRHKQGQPVLVGTVAIETSELISKMLTRKGVRHNILNAKNHAREADIIAEAGMKGAV HHHHHCCCCCCEEEEEEEECHHHHHHHHHHHCCHHHHHHCCHHHHHHHHHHHHCCCCCEE TIATNMAGRGTDIKLGDDIKNIGLAVIGTERHESRRIDNQLRGRAGRQGDPGVTQFYLSM EEEECCCCCCCCEEECCCHHHCCEEEEECCHHHHHHHHHHHHCCCCCCCCCCHHEEEECH EDELMRRFGSDNMKAMMDRLGMDDSQPIESKMVSRAVESAQKRVEGNNYDARKQLLQYDD HHHHHHHHCCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHH VLRQQREVIYKQRQEVMESENLRGIIEGMMKSTVERAVALHTQEEIEEDWNIKGLVDYLN HHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHH TNLLQEGDVKEEELRRLAPEEMSEPIIAKLIERYNDKEKLMPEEQMREFEKVVVFRVVDT HHHCCCCCCCHHHHHHCCHHHHCCHHHHHHHHHHCCHHHCCCHHHHHHHHHHHHHHHHCC KWTEHIDAMDHLREGIHLRAYGQIDPLREYQMEGFAMFESMIASIEEEISRYIMKAEIEQ HHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH NLERQEVVQGEAVHPSSDGEEAKKKPVVKGDQVGRNDLCKCGSGKKYKNCCGIGK CCHHHHHHCCCCCCCCCCCHHHHHCCCCCCCCCCCHHHHCCCCCCCHHHHCCCCC
PDB accession: NA
Resolution: NA
Structure class: Unstructured
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 6.0
TargetDB status: NA
Availability: NA
References: NA