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The map label for this gene is hmuU [H]

Identifier: 227817147

GI number: 227817147

Start: 4175267

End: 4176256

Strand: Reverse

Name: hmuU [H]

Synonym: BAMEG_4633

Alternate gene names: 227817147

Gene position: 4176256-4175267 (Counterclockwise)

Preceding gene: 227817148

Following gene: 227817146

Centisome position: 79.85

GC content: 39.6

Gene sequence:

>990_bases
TTGCGAAAAAAAAGATGGATCATAGCAGTTAGTTTAGTTATATTAACGATTTTAGGTCTTTTTTACGGCCTTTTCGCAGG
AAGCTTATCCTTTTCTTTACGAGATATTCTAACAGGGATACAAGATGAAGGGTCGACAGTTCATCGAATTGTATGGGACC
TTCGTATACCAAGAGTGCTCGTTGGATTTATAGTAGGAACATGTTTAGCTGCATCAGGTGCATTATTACAAGGAGTTATG
AGAAACCCTCTTGCAGACCCCGGTATTATTGGGGTTTCATCTGGAGCAGGCCTTGTAGCAATCGTAATTATGATTTTATT
CCCTCAGCATATGGCTTTTTTACCGCTCGGGGCGTTTTTAGGAGCTTTCATAACGGCGATGATCATTTATGCTTTATCAT
GGCAAAAAGGGGCGCCACCTTCAAGAATTGTCTTAGTAGGCGTGTCAATCAATGCATTAATTGGTGCAGCAACATCAGCA
TTAATGTTATTGCATAGTGACAAAGTACAGTCCGTGTTACCGTGGTTAGCAGGTGGCATTGGTGGTGTGAGCTGGGCACA
TTTAAACATGATTATTTATTATGCAATATTCGCTATTATATTGGCTTTCTTTGGTATCAAGCATATTCGAGTATTAATGC
TTGGAGATGAAATGGCGAAATTATTGGGGCATAACGTGGAGAGAAGCCGGTTTTATTTAATAGTAGTAAGTACATTATTA
GCTGGAATTGCGGTGAGTGTTTCTGGTCTTATTGGATTTGTCGGTCTCGTCGTACCACATATGTTACGTTTATTAGTTGG
GAATGACTATAAATATTTACTGCCATTATCATGCCTTGGCGGAGGAATATTACTTGTTTTCGCAGATGCGATAGCTCGAA
GTTGGTTCGATCCAATTGAATTACCTGTCGGTATTTTATTATCCTTCTTAGGCGGTCCGTTCTTCTTATATTTAATTCAT
AGGGGAGGCAAGCAACGTGATTTCCGTTAA

Upstream 100 bases:

>100_bases
AGTTACAGAAGCGATGGACTTTATGTATAAAAGTATACAAGATGTAAGGAAATGATAAGTATGGAAAGTAGTGAAGTAGT
AAGGGAAGAGGAACATCCTT

Downstream 100 bases:

>100_bases
CAAAGTGTTTTACGCACATTCTGAAAGATTTCAAATGCAAAATATGAATGTACATATTAAAGCTGGAGAGGTCGTTAGTT
TAATTGGACCGAATGGGTCA

Product: iron compound ABC transporter, permease protein

Products: ADP; phosphate; iron dicitrate [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 329; Mature: 329

Protein sequence:

>329_residues
MRKKRWIIAVSLVILTILGLFYGLFAGSLSFSLRDILTGIQDEGSTVHRIVWDLRIPRVLVGFIVGTCLAASGALLQGVM
RNPLADPGIIGVSSGAGLVAIVIMILFPQHMAFLPLGAFLGAFITAMIIYALSWQKGAPPSRIVLVGVSINALIGAATSA
LMLLHSDKVQSVLPWLAGGIGGVSWAHLNMIIYYAIFAIILAFFGIKHIRVLMLGDEMAKLLGHNVERSRFYLIVVSTLL
AGIAVSVSGLIGFVGLVVPHMLRLLVGNDYKYLLPLSCLGGGILLVFADAIARSWFDPIELPVGILLSFLGGPFFLYLIH
RGGKQRDFR

Sequences:

>Translated_329_residues
MRKKRWIIAVSLVILTILGLFYGLFAGSLSFSLRDILTGIQDEGSTVHRIVWDLRIPRVLVGFIVGTCLAASGALLQGVM
RNPLADPGIIGVSSGAGLVAIVIMILFPQHMAFLPLGAFLGAFITAMIIYALSWQKGAPPSRIVLVGVSINALIGAATSA
LMLLHSDKVQSVLPWLAGGIGGVSWAHLNMIIYYAIFAIILAFFGIKHIRVLMLGDEMAKLLGHNVERSRFYLIVVSTLL
AGIAVSVSGLIGFVGLVVPHMLRLLVGNDYKYLLPLSCLGGGILLVFADAIARSWFDPIELPVGILLSFLGGPFFLYLIH
RGGKQRDFR
>Mature_329_residues
MRKKRWIIAVSLVILTILGLFYGLFAGSLSFSLRDILTGIQDEGSTVHRIVWDLRIPRVLVGFIVGTCLAASGALLQGVM
RNPLADPGIIGVSSGAGLVAIVIMILFPQHMAFLPLGAFLGAFITAMIIYALSWQKGAPPSRIVLVGVSINALIGAATSA
LMLLHSDKVQSVLPWLAGGIGGVSWAHLNMIIYYAIFAIILAFFGIKHIRVLMLGDEMAKLLGHNVERSRFYLIVVSTLL
AGIAVSVSGLIGFVGLVVPHMLRLLVGNDYKYLLPLSCLGGGILLVFADAIARSWFDPIELPVGILLSFLGGPFFLYLIH
RGGKQRDFR

Specific function: Part of the binding-protein-dependent transport system for hemin; probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG0609

COG function: function code P; ABC-type Fe3+-siderophore transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790740, Length=319, Percent_Identity=35.1097178683386, Blast_Score=164, Evalue=1e-41,
Organism=Escherichia coli, GI1786804, Length=307, Percent_Identity=30.9446254071661, Blast_Score=142, Evalue=3e-35,
Organism=Escherichia coli, GI1790741, Length=318, Percent_Identity=31.1320754716981, Blast_Score=136, Evalue=2e-33,
Organism=Escherichia coli, GI1788004, Length=277, Percent_Identity=34.2960288808664, Blast_Score=129, Evalue=3e-31,
Organism=Escherichia coli, GI1786805, Length=278, Percent_Identity=35.2517985611511, Blast_Score=127, Evalue=1e-30,
Organism=Escherichia coli, GI1786347, Length=279, Percent_Identity=30.1075268817204, Blast_Score=113, Evalue=2e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000522 [H]

Pfam domain/function: PF01032 FecCD [H]

EC number: NA

Molecular weight: Translated: 35445; Mature: 35445

Theoretical pI: Translated: 10.31; Mature: 10.31

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRKKRWIIAVSLVILTILGLFYGLFAGSLSFSLRDILTGIQDEGSTVHRIVWDLRIPRVL
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHH
VGFIVGTCLAASGALLQGVMRNPLADPGIIGVSSGAGLVAIVIMILFPQHMAFLPLGAFL
HHHHHHHHHHHCHHHHHHHHHCCCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHH
GAFITAMIIYALSWQKGAPPSRIVLVGVSINALIGAATSALMLLHSDKVQSVLPWLAGGI
HHHHHHHHHHHHCCCCCCCCCEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
GGVSWAHLNMIIYYAIFAIILAFFGIKHIRVLMLGDEMAKLLGHNVERSRFYLIVVSTLL
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCCCHHHHHHHHHHHHH
AGIAVSVSGLIGFVGLVVPHMLRLLVGNDYKYLLPLSCLGGGILLVFADAIARSWFDPIE
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEHHHHCCHHHHHHHHHHHHHCCCHHH
LPVGILLSFLGGPFFLYLIHRGGKQRDFR
HHHHHHHHHHCCHHHHHHHHCCCCCCCCC
>Mature Secondary Structure
MRKKRWIIAVSLVILTILGLFYGLFAGSLSFSLRDILTGIQDEGSTVHRIVWDLRIPRVL
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHH
VGFIVGTCLAASGALLQGVMRNPLADPGIIGVSSGAGLVAIVIMILFPQHMAFLPLGAFL
HHHHHHHHHHHCHHHHHHHHHCCCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHH
GAFITAMIIYALSWQKGAPPSRIVLVGVSINALIGAATSALMLLHSDKVQSVLPWLAGGI
HHHHHHHHHHHHCCCCCCCCCEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
GGVSWAHLNMIIYYAIFAIILAFFGIKHIRVLMLGDEMAKLLGHNVERSRFYLIVVSTLL
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCCCHHHHHHHHHHHHH
AGIAVSVSGLIGFVGLVVPHMLRLLVGNDYKYLLPLSCLGGGILLVFADAIARSWFDPIE
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEHHHHCCHHHHHHHHHHHHHCCCHHH
LPVGILLSFLGGPFFLYLIHRGGKQRDFR
HHHHHHHHHHCCHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; iron dicitrate [Periplasm]; H2O [C]

Specific reaction: ATP + iron dicitrate [Periplasm] + H2O = ADP + phosphate + iron dicitrate [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9026634; 11586360; 12142430 [H]