| Definition | Bacillus anthracis str. CDC 684, complete genome. |
|---|---|
| Accession | NC_012581 |
| Length | 5,230,115 |
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The map label for this gene is comEC [H]
Identifier: 227817101
GI number: 227817101
Start: 4139884
End: 4142052
Strand: Reverse
Name: comEC [H]
Synonym: BAMEG_4587
Alternate gene names: 227817101
Gene position: 4142052-4139884 (Counterclockwise)
Preceding gene: 227817103
Following gene: 227817099
Centisome position: 79.2
GC content: 36.1
Gene sequence:
>2169_bases ATGATAGTGTGTTTTAGTGGCGCTATGTACACCACGTATGTTCAAGGACAAAATAAGCCTCTGGGAGAGTCCTACGAAGC TACAAGAGGAGTGATTTATAATACACCTCTTATTAACGGGGATCGCCTATCATTTCAAGTTGAAGATCAGAATAAAAATA TAGTGCAGTTAAGTTACAAAATGAAATCAGCCTCGGAAAAGAAACAAATGCGACAATTACATGCAGGAGTGTCATGTATA TTTGATGGTGAGAGGAAAGAACCACAAATAGCTCGGAATTTTCATGGGTTTAATTATCGTGATTATTTATATAAGCAAAA TATTCATTTCATATTGGAAGCTACATATATTTCTGAATGCCGTAAAACATCGTTGTCACTTGTGCAATGGATTCTTCTTT TGAGGCAGCAAGCAATCTTAGGAGTTACAGAAATGTTTCCAGAGCAATCAGGCGCTTTTATGAACGCGTTACTATTTGGT GATAGACAACAAATGACATTTGAAGTTGAAGGGCAATATCAACAATTCGGTCTTGTGCATTTGTTGGCGATTTCAGGATC GCATATCGTATTGTTAATGGTGATTGTGTATTTTATTTTGCTAAGAAGTGGTGTGACAAGGGAGATAGCAACAGTATGTC TTATCTTCTTCATTCCTATATATATGATTTTAGCAGGAGCGTCACCGTCTGTTATAAGAGCTTCTATAACAGGAGTTTTA ATGTTAATTGCTTTTATGTGTTCTATTCGTTTATCTAGCTTAGATGCTTTAAGTATAACAGCTATATGTATGCTTATATT TGATCCATATCTCGTGTTTAATATTGGCTTTCAGTTTTCTTTTGTTGGGAGTTTTGCTTTACTTTTATCTGCCCCGCTCT TACTAGAGAGTGGTAATGGAGTAATTAGAAATTCTATTTATATTTCTCTTATTTCACAGCTCGTTAGTACTCCGATTTTG TTATATCACTTCGGTTATTATTCTCCATATAGTATTTTTCTAAATATCCTTTACGTTCCGTTTTTATCTCTCATTGTATT GCCGTGTAGTATTATTATTTTGATATGTTTGCCGATCATCCCGTTTCTTGCAAAAAGCTTTGCGAATGTACTATCAATAG GTTTGAATCTTTCTAATGATTTTTTAAGTTATTGTGAAAGTTTACCATTTACCCGTCTTAATTTCGGGCAAACACCTATA CTTCTTGTAGCCTTATATTGCGTGAGTATTATTAGTGTATTGATGGTTTGGGAAAGGCGAATATCTAAGGGAATGGTGTT TATATTTGCGGGCATATTTCTTTTTATTAGTACAGGTCATTATGTATATCCGTATTTTCGAGAAAGTGGGAGTGTTACAT TTCTTGATGTTGGCCAGGGGGATGCAATATTAATTCGCCTCCCGTATGATCAAGAGATTTACCTTATTGACACTGGTGGA ACAATTCGTTTAAACAAGGAAGAATGGCAACGGAAAAAACATGAATTTTCTGTTGGAAATGATGTTTTGATCCCTTATTT ACAAAAGGAAGGTATTAAAAAAATTGATAAATTAATTGTAACGCATGGAGATGCAGATCATATCGGTGCTGCACAAGAAT TATTATCAAATATAACCGTAAAAGAAGTTGTATTTGGTCGAAAGGAACAAGAGGCAATATTAGAAAAAGCAGTAAAGAAA CAGGCGTTAGAAAAGGAAGTGAAAATAAGTGAAGTGGGGGAAGGAGAGAGTTGGCGCGTAAATGAAGCGGAATTTTTTGT GCTAGCACCAACAGGGAAAGAAAGAAGTGAAAATAACGCTTCAATTGTACTGTGGGCAAAATTAGGAGGGATAACGTGGC TGTTTACAGGTGATTTAGAAGAAGGAGAGAAGGGTTTAGTAGCTACATATCCAGATTTACGGGCGGATGTTTTAAAGGTT GCTCATCATGGAAGTAATACGTCATCTATAACGCCTTTTTTGAGCGCCGTACAGCCTAATATAGCGATTATTTCTGTCGG TGAACGGAATAGGTATGGGCACCCTCATAAGGAAGGTATAGAGCGTTTTGAGAAGATGGCGATTGAAATATGGCGCACGG ATAAGCAAGGTGCTATTTCCTATGTTTTTAAAGAGGAACGCGGAACGTTTCGTAGCAAAATCACATATGATGAAACACGG AATAGATAA
Upstream 100 bases:
>100_bases AATCGCCTTCTCCTCTTCAGTTGTATTGCTGACTTGTTGTCTCGGTCTATATGTTTTCTTTTGTTTGTATCGTACTTCGC GTAAAACCTTCCTATATTGT
Downstream 100 bases:
>100_bases AAAAAGACTGCTAGTAAGCAGCAGTCTTTAAGAACCGATAAATTTAATAACAGTTGCAATGATGAAAAGTGTTGCGAAAA AACCAAATGAGACGATAAAT
Product: DNA internalization-related competence protein ComEC/Rec2
Products: NA
Alternate protein names: NA
Number of amino acids: Translated: 722; Mature: 722
Protein sequence:
>722_residues MIVCFSGAMYTTYVQGQNKPLGESYEATRGVIYNTPLINGDRLSFQVEDQNKNIVQLSYKMKSASEKKQMRQLHAGVSCI FDGERKEPQIARNFHGFNYRDYLYKQNIHFILEATYISECRKTSLSLVQWILLLRQQAILGVTEMFPEQSGAFMNALLFG DRQQMTFEVEGQYQQFGLVHLLAISGSHIVLLMVIVYFILLRSGVTREIATVCLIFFIPIYMILAGASPSVIRASITGVL MLIAFMCSIRLSSLDALSITAICMLIFDPYLVFNIGFQFSFVGSFALLLSAPLLLESGNGVIRNSIYISLISQLVSTPIL LYHFGYYSPYSIFLNILYVPFLSLIVLPCSIIILICLPIIPFLAKSFANVLSIGLNLSNDFLSYCESLPFTRLNFGQTPI LLVALYCVSIISVLMVWERRISKGMVFIFAGIFLFISTGHYVYPYFRESGSVTFLDVGQGDAILIRLPYDQEIYLIDTGG TIRLNKEEWQRKKHEFSVGNDVLIPYLQKEGIKKIDKLIVTHGDADHIGAAQELLSNITVKEVVFGRKEQEAILEKAVKK QALEKEVKISEVGEGESWRVNEAEFFVLAPTGKERSENNASIVLWAKLGGITWLFTGDLEEGEKGLVATYPDLRADVLKV AHHGSNTSSITPFLSAVQPNIAIISVGERNRYGHPHKEGIERFEKMAIEIWRTDKQGAISYVFKEERGTFRSKITYDETR NR
Sequences:
>Translated_722_residues MIVCFSGAMYTTYVQGQNKPLGESYEATRGVIYNTPLINGDRLSFQVEDQNKNIVQLSYKMKSASEKKQMRQLHAGVSCI FDGERKEPQIARNFHGFNYRDYLYKQNIHFILEATYISECRKTSLSLVQWILLLRQQAILGVTEMFPEQSGAFMNALLFG DRQQMTFEVEGQYQQFGLVHLLAISGSHIVLLMVIVYFILLRSGVTREIATVCLIFFIPIYMILAGASPSVIRASITGVL MLIAFMCSIRLSSLDALSITAICMLIFDPYLVFNIGFQFSFVGSFALLLSAPLLLESGNGVIRNSIYISLISQLVSTPIL LYHFGYYSPYSIFLNILYVPFLSLIVLPCSIIILICLPIIPFLAKSFANVLSIGLNLSNDFLSYCESLPFTRLNFGQTPI LLVALYCVSIISVLMVWERRISKGMVFIFAGIFLFISTGHYVYPYFRESGSVTFLDVGQGDAILIRLPYDQEIYLIDTGG TIRLNKEEWQRKKHEFSVGNDVLIPYLQKEGIKKIDKLIVTHGDADHIGAAQELLSNITVKEVVFGRKEQEAILEKAVKK QALEKEVKISEVGEGESWRVNEAEFFVLAPTGKERSENNASIVLWAKLGGITWLFTGDLEEGEKGLVATYPDLRADVLKV AHHGSNTSSITPFLSAVQPNIAIISVGERNRYGHPHKEGIERFEKMAIEIWRTDKQGAISYVFKEERGTFRSKITYDETR NR >Mature_722_residues MIVCFSGAMYTTYVQGQNKPLGESYEATRGVIYNTPLINGDRLSFQVEDQNKNIVQLSYKMKSASEKKQMRQLHAGVSCI FDGERKEPQIARNFHGFNYRDYLYKQNIHFILEATYISECRKTSLSLVQWILLLRQQAILGVTEMFPEQSGAFMNALLFG DRQQMTFEVEGQYQQFGLVHLLAISGSHIVLLMVIVYFILLRSGVTREIATVCLIFFIPIYMILAGASPSVIRASITGVL MLIAFMCSIRLSSLDALSITAICMLIFDPYLVFNIGFQFSFVGSFALLLSAPLLLESGNGVIRNSIYISLISQLVSTPIL LYHFGYYSPYSIFLNILYVPFLSLIVLPCSIIILICLPIIPFLAKSFANVLSIGLNLSNDFLSYCESLPFTRLNFGQTPI LLVALYCVSIISVLMVWERRISKGMVFIFAGIFLFISTGHYVYPYFRESGSVTFLDVGQGDAILIRLPYDQEIYLIDTGG TIRLNKEEWQRKKHEFSVGNDVLIPYLQKEGIKKIDKLIVTHGDADHIGAAQELLSNITVKEVVFGRKEQEAILEKAVKK QALEKEVKISEVGEGESWRVNEAEFFVLAPTGKERSENNASIVLWAKLGGITWLFTGDLEEGEKGLVATYPDLRADVLKV AHHGSNTSSITPFLSAVQPNIAIISVGERNRYGHPHKEGIERFEKMAIEIWRTDKQGAISYVFKEERGTFRSKITYDETR NR
Specific function: The comE operon is required for the binding and uptake of transforming DNA. ComEC is required for internalization but is dispensable for DNA binding [H]
COG id: COG2333
COG function: function code R; Predicted hydrolase (metallo-beta-lactamase superfamily)
Gene ontology:
Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]
Metaboloic importance: Unknown [C]
Operon status: Not Known
Operon components: None
Similarity: To H.influenzae REC2, N.gonorrhoeae ComA and E.coli YcaI [H]
Homologues:
None
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR001279 - InterPro: IPR004477 - InterPro: IPR004797 [H]
Pfam domain/function: PF03772 Competence; PF00753 Lactamase_B [H]
EC number: NA
Molecular weight: Translated: 81447; Mature: 81447
Theoretical pI: Translated: 7.35; Mature: 7.35
Prosite motif: NA
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
1.4 %Cys (Translated Protein) 2.1 %Met (Translated Protein) 3.5 %Cys+Met (Translated Protein) 1.4 %Cys (Mature Protein) 2.1 %Met (Mature Protein) 3.5 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MIVCFSGAMYTTYVQGQNKPLGESYEATRGVIYNTPLINGDRLSFQVEDQNKNIVQLSYK CEEEEECCEEEEEEECCCCCCCCCHHHCCCEEEECCEECCCEEEEEEECCCCCEEEEEEE MKSASEKKQMRQLHAGVSCIFDGERKEPQIARNFHGFNYRDYLYKQNIHFILEATYISEC HHHHHHHHHHHHHHCCCEEEECCCCCCCHHHHHCCCCCHHHHHHHCCEEEEEEHHHHHHH RKTSLSLVQWILLLRQQAILGVTEMFPEQSGAFMNALLFGDRQQMTFEVEGQYQQFGLVH HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCCCCEEEEEECCCHHHHCCEE LLAISGSHIVLLMVIVYFILLRSGVTREIATVCLIFFIPIYMILAGASPSVIRASITGVL EEEECCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHH MLIAFMCSIRLSSLDALSITAICMLIFDPYLVFNIGFQFSFVGSFALLLSAPLLLESGNG HHHHHHHHHHHHCCCHHHHHHHHHHHHCCHHEEEECCCHHHHHHHHHHHCCCCEEECCCC VIRNSIYISLISQLVSTPILLYHFGYYSPYSIFLNILYVPFLSLIVLPCSIIILICLPII EEHHHHHHHHHHHHHHCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH PFLAKSFANVLSIGLNLSNDFLSYCESLPFTRLNFGQTPILLVALYCVSIISVLMVWERR HHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCEECCCCCHHHHHHHHHHHHHHHHHHHHHH ISKGMVFIFAGIFLFISTGHYVYPYFRESGSVTFLDVGQGDAILIRLPYDQEIYLIDTGG HHCCHHHHHHHHHHHHHCCCEEEEEEECCCCEEEEEECCCCEEEEEECCCCEEEEEECCC TIRLNKEEWQRKKHEFSVGNDVLIPYLQKEGIKKIDKLIVTHGDADHIGAAQELLSNITV EEEECHHHHHHHHHCCCCCCCEEEHHHHHHHHHHHHHHHEECCCCHHHHHHHHHHHCCCH KEVVFGRKEQEAILEKAVKKQALEKEVKISEVGEGESWRVNEAEFFVLAPTGKERSENNA HHHHHCCCHHHHHHHHHHHHHHHHHHCCHHCCCCCCCEEECCCEEEEECCCCCCCCCCCC SIVLWAKLGGITWLFTGDLEEGEKGLVATYPDLRADVLKVAHHGSNTSSITPFLSAVQPN EEEEEEEECCEEEEEECCCCCCCCCCEEECCHHHHHHHHHHHCCCCCCCHHHHHHHCCCC IAIISVGERNRYGHPHKEGIERFEKMAIEIWRTDKQGAISYVFKEERGTFRSKITYDETR EEEEEECCCCCCCCCHHHHHHHHHHHHHHHEECCCCCCEEEEEECCCCCHHHCEECHHCC NR CC >Mature Secondary Structure MIVCFSGAMYTTYVQGQNKPLGESYEATRGVIYNTPLINGDRLSFQVEDQNKNIVQLSYK CEEEEECCEEEEEEECCCCCCCCCHHHCCCEEEECCEECCCEEEEEEECCCCCEEEEEEE MKSASEKKQMRQLHAGVSCIFDGERKEPQIARNFHGFNYRDYLYKQNIHFILEATYISEC HHHHHHHHHHHHHHCCCEEEECCCCCCCHHHHHCCCCCHHHHHHHCCEEEEEEHHHHHHH RKTSLSLVQWILLLRQQAILGVTEMFPEQSGAFMNALLFGDRQQMTFEVEGQYQQFGLVH HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCCCCEEEEEECCCHHHHCCEE LLAISGSHIVLLMVIVYFILLRSGVTREIATVCLIFFIPIYMILAGASPSVIRASITGVL EEEECCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHH MLIAFMCSIRLSSLDALSITAICMLIFDPYLVFNIGFQFSFVGSFALLLSAPLLLESGNG HHHHHHHHHHHHCCCHHHHHHHHHHHHCCHHEEEECCCHHHHHHHHHHHCCCCEEECCCC VIRNSIYISLISQLVSTPILLYHFGYYSPYSIFLNILYVPFLSLIVLPCSIIILICLPII EEHHHHHHHHHHHHHHCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH PFLAKSFANVLSIGLNLSNDFLSYCESLPFTRLNFGQTPILLVALYCVSIISVLMVWERR HHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCEECCCCCHHHHHHHHHHHHHHHHHHHHHH ISKGMVFIFAGIFLFISTGHYVYPYFRESGSVTFLDVGQGDAILIRLPYDQEIYLIDTGG HHCCHHHHHHHHHHHHHCCCEEEEEEECCCCEEEEEECCCCEEEEEECCCCEEEEEECCC TIRLNKEEWQRKKHEFSVGNDVLIPYLQKEGIKKIDKLIVTHGDADHIGAAQELLSNITV EEEECHHHHHHHHHCCCCCCCEEEHHHHHHHHHHHHHHHEECCCCHHHHHHHHHHHCCCH KEVVFGRKEQEAILEKAVKKQALEKEVKISEVGEGESWRVNEAEFFVLAPTGKERSENNA HHHHHCCCHHHHHHHHHHHHHHHHHHCCHHCCCCCCCEEECCCEEEEECCCCCCCCCCCC SIVLWAKLGGITWLFTGDLEEGEKGLVATYPDLRADVLKVAHHGSNTSSITPFLSAVQPN EEEEEEEECCEEEEEECCCCCCCCCCEEECCHHHHHHHHHHHCCCCCCCHHHHHHHCCCC IAIISVGERNRYGHPHKEGIERFEKMAIEIWRTDKQGAISYVFKEERGTFRSKITYDETR EEEEEECCCCCCCCCHHHHHHHHHHHHHHHEECCCCCCEEEEEECCCCCHHHCEECHHCC NR CC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 6.0
TargetDB status: NA
Availability: NA
References: 7968523; 8969508; 9384377 [H]