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The map label for this gene is nagA [H]

Identifier: 227816833

GI number: 227816833

Start: 3911074

End: 3912216

Strand: Reverse

Name: nagA [H]

Synonym: BAMEG_4315

Alternate gene names: 227816833

Gene position: 3912216-3911074 (Counterclockwise)

Preceding gene: 227816834

Following gene: 227816832

Centisome position: 74.8

GC content: 37.18

Gene sequence:

>1143_bases
ATGAAAACGCAAGTTGTCATCAATGCCAAAATTTATACAGGTCAAGAAGTAGTAGAAAACGGATTTATTCGTTACGCAGA
AACAATTAAAGAAATTGGTTTGATGGCTCAATATGTATCACAAGAAAATGAAACTGTTTTAGATGCAGCAGGGAAGATTG
TGATTCCAGGTATGATTGATGTTCATATTCATGGTGGATACGATATTGATGCGATGGATGCAAATAGCGATGGGTTAGTA
ACTCTAGGGAAAGAAATGTTAAAAGAAGGAGTTACAACTTACTTCCCAACAACAATGACACAAGCTCCAGAAGCAATCGA
AGCAGCACTACATGCTGCGAAGGAAGCGAAAGAAAAAGGAGCACATTTCGAATATATTCACTTAGAAGGACCGTATGTTT
CAAAAAAACGTGCAGGTGCACAACCACTTGAACATATTGTTCCTGCTAATATTGAACAATTTAAACAATGGCAGGAAGCA
AGCGGAAATCTAATTAAATTAGTAACATACGCACCTGAAGAAGAAGGAGCATTAGAGTTTGAGCAGTATCTTGCTGAAAC
TGGTGTTGTCGGCACAATGGGGCATACAGATGCAATTGATGCGCAATTAAAAAACAGAAACATTACACATGCAACGCATT
TATACAATCAAATGCGTGGATTACATCACCGTGAACCAGGAGTTGTTGGTCATGTGTTATTAAATCCAGATGTAATGGTT
GAAGTAATTACAGATGGTATTCACATTCACCCTGATATGGTGAAATTAGCATATAAATTAAAAGGACCGAAAAAAGTAAG
TGTTATTACTGACGCAATGCGTGCAAAAGGTCTTGAAGATGGATTATATGAGCTTGGCGGACAGCCAGTACATGTAAAAG
ATGGTAGTGCTCGATTAGAAGATGGAACGCTAGCTGGTAGTATTCTAAAAATGGATCAAGCTTTCCGAAATGTAATTGAA
TTTACAGGTTGTTCAATCGAAGATGCAGTACTGATGACATCAGTTAACCAAGCAGAAGAGTTTAGATTAAATAATAAAGG
TGCATTAGCGGTAGGAAAAGATGCAGACTTTGTTGTGATGAATGAAGATTTACATGTATATGATACGGTTCGTTTAGGAA
TTCATATGAAGGAAGGGAAGTAA

Upstream 100 bases:

>100_bases
TTAGAATGTATAGACAACTACTCGCGCATATATTAAGATGGAATTAGGCGAATAAGGTAATAATAACAAGTAGGTATTTC
ATGGGAAAGGATCGATGAAA

Downstream 100 bases:

>100_bases
TTAAATGAATATTCTTGTTGTAAAAACTCCAGAAGAACTAGCAGAAGCAGGTTATAAATTAATTGAAGAAGTTGTAAAAA
CAAAAGAAAATCCAACATTA

Product: N-acetylglucosamine-6-phosphate deacetylase

Products: NA

Alternate protein names: GlcNAc 6-P deacetylase [H]

Number of amino acids: Translated: 380; Mature: 380

Protein sequence:

>380_residues
MKTQVVINAKIYTGQEVVENGFIRYAETIKEIGLMAQYVSQENETVLDAAGKIVIPGMIDVHIHGGYDIDAMDANSDGLV
TLGKEMLKEGVTTYFPTTMTQAPEAIEAALHAAKEAKEKGAHFEYIHLEGPYVSKKRAGAQPLEHIVPANIEQFKQWQEA
SGNLIKLVTYAPEEEGALEFEQYLAETGVVGTMGHTDAIDAQLKNRNITHATHLYNQMRGLHHREPGVVGHVLLNPDVMV
EVITDGIHIHPDMVKLAYKLKGPKKVSVITDAMRAKGLEDGLYELGGQPVHVKDGSARLEDGTLAGSILKMDQAFRNVIE
FTGCSIEDAVLMTSVNQAEEFRLNNKGALAVGKDADFVVMNEDLHVYDTVRLGIHMKEGK

Sequences:

>Translated_380_residues
MKTQVVINAKIYTGQEVVENGFIRYAETIKEIGLMAQYVSQENETVLDAAGKIVIPGMIDVHIHGGYDIDAMDANSDGLV
TLGKEMLKEGVTTYFPTTMTQAPEAIEAALHAAKEAKEKGAHFEYIHLEGPYVSKKRAGAQPLEHIVPANIEQFKQWQEA
SGNLIKLVTYAPEEEGALEFEQYLAETGVVGTMGHTDAIDAQLKNRNITHATHLYNQMRGLHHREPGVVGHVLLNPDVMV
EVITDGIHIHPDMVKLAYKLKGPKKVSVITDAMRAKGLEDGLYELGGQPVHVKDGSARLEDGTLAGSILKMDQAFRNVIE
FTGCSIEDAVLMTSVNQAEEFRLNNKGALAVGKDADFVVMNEDLHVYDTVRLGIHMKEGK
>Mature_380_residues
MKTQVVINAKIYTGQEVVENGFIRYAETIKEIGLMAQYVSQENETVLDAAGKIVIPGMIDVHIHGGYDIDAMDANSDGLV
TLGKEMLKEGVTTYFPTTMTQAPEAIEAALHAAKEAKEKGAHFEYIHLEGPYVSKKRAGAQPLEHIVPANIEQFKQWQEA
SGNLIKLVTYAPEEEGALEFEQYLAETGVVGTMGHTDAIDAQLKNRNITHATHLYNQMRGLHHREPGVVGHVLLNPDVMV
EVITDGIHIHPDMVKLAYKLKGPKKVSVITDAMRAKGLEDGLYELGGQPVHVKDGSARLEDGTLAGSILKMDQAFRNVIE
FTGCSIEDAVLMTSVNQAEEFRLNNKGALAVGKDADFVVMNEDLHVYDTVRLGIHMKEGK

Specific function: N-acetylglucosamine utilization. [C]

COG id: COG1820

COG function: function code G; N-acetylglucosamine-6-phosphate deacetylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the nagA family [H]

Homologues:

Organism=Homo sapiens, GI21361513, Length=416, Percent_Identity=30.7692307692308, Blast_Score=172, Evalue=5e-43,
Organism=Homo sapiens, GI224922791, Length=416, Percent_Identity=30.7692307692308, Blast_Score=172, Evalue=5e-43,
Organism=Escherichia coli, GI1786892, Length=371, Percent_Identity=28.5714285714286, Blast_Score=141, Evalue=9e-35,
Organism=Caenorhabditis elegans, GI17553768, Length=349, Percent_Identity=34.9570200573066, Blast_Score=184, Evalue=8e-47,
Organism=Drosophila melanogaster, GI19920392, Length=345, Percent_Identity=34.2028985507246, Blast_Score=186, Evalue=3e-47,
Organism=Drosophila melanogaster, GI281361140, Length=359, Percent_Identity=32.8690807799443, Blast_Score=179, Evalue=3e-45,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006680
- InterPro:   IPR003764
- InterPro:   IPR011059 [H]

Pfam domain/function: PF01979 Amidohydro_1 [H]

EC number: =3.5.1.25 [H]

Molecular weight: Translated: 41711; Mature: 41711

Theoretical pI: Translated: 5.28; Mature: 5.28

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTQVVINAKIYTGQEVVENGFIRYAETIKEIGLMAQYVSQENETVLDAAGKIVIPGMID
CCCEEEEEEEEECCHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCEEECCCCCEEECCEEE
VHIHGGYDIDAMDANSDGLVTLGKEMLKEGVTTYFPTTMTQAPEAIEAALHAAKEAKEKG
EEEECCCEEEEECCCCCCEEHHHHHHHHCCCCEECCCHHHCCHHHHHHHHHHHHHHHHCC
AHFEYIHLEGPYVSKKRAGAQPLEHIVPANIEQFKQWQEASGNLIKLVTYAPEEEGALEF
CCEEEEEECCCCCCHHHCCCCCHHHHCCCCHHHHHHHHHCCCCEEEEEEECCCCCCCHHH
EQYLAETGVVGTMGHTDAIDAQLKNRNITHATHLYNQMRGLHHREPGVVGHVLLNPDVMV
HHHHHHCCCEECCCCCCHHHHHHCCCCCHHHHHHHHHHHCCCCCCCCCEEEEEECCCEEE
EVITDGIHIHPDMVKLAYKLKGPKKVSVITDAMRAKGLEDGLYELGGQPVHVKDGSARLE
EEECCCEEECHHHHHHHHHCCCCCEEHHHHHHHHHCCCCCHHHHHCCCEEEEECCCCCCC
DGTLAGSILKMDQAFRNVIEFTGCSIEDAVLMTSVNQAEEFRLNNKGALAVGKDADFVVM
CCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHCCCCHHHHEECCCCCEEECCCCCEEEE
NEDLHVYDTVRLGIHMKEGK
CCCEEEEEEEEEEEEEECCC
>Mature Secondary Structure
MKTQVVINAKIYTGQEVVENGFIRYAETIKEIGLMAQYVSQENETVLDAAGKIVIPGMID
CCCEEEEEEEEECCHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCEEECCCCCEEECCEEE
VHIHGGYDIDAMDANSDGLVTLGKEMLKEGVTTYFPTTMTQAPEAIEAALHAAKEAKEKG
EEEECCCEEEEECCCCCCEEHHHHHHHHCCCCEECCCHHHCCHHHHHHHHHHHHHHHHCC
AHFEYIHLEGPYVSKKRAGAQPLEHIVPANIEQFKQWQEASGNLIKLVTYAPEEEGALEF
CCEEEEEECCCCCCHHHCCCCCHHHHCCCCHHHHHHHHHCCCCEEEEEEECCCCCCCHHH
EQYLAETGVVGTMGHTDAIDAQLKNRNITHATHLYNQMRGLHHREPGVVGHVLLNPDVMV
HHHHHHCCCEECCCCCCHHHHHHCCCCCHHHHHHHHHHHCCCCCCCCCEEEEEECCCEEE
EVITDGIHIHPDMVKLAYKLKGPKKVSVITDAMRAKGLEDGLYELGGQPVHVKDGSARLE
EEECCCEEECHHHHHHHHHCCCCCEEHHHHHHHHHCCCCCHHHHHCCCEEEEECCCCCCC
DGTLAGSILKMDQAFRNVIEFTGCSIEDAVLMTSVNQAEEFRLNNKGALAVGKDADFVVM
CCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHCCCCHHHHEECCCCCEEECCCCCEEEE
NEDLHVYDTVRLGIHMKEGK
CCCEEEEEEEEEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]