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The map label for this gene is ntdR [H]

Identifier: 227816064

GI number: 227816064

Start: 3169922

End: 3170899

Strand: Reverse

Name: ntdR [H]

Synonym: BAMEG_3490

Alternate gene names: 227816064

Gene position: 3170899-3169922 (Counterclockwise)

Preceding gene: 227816065

Following gene: 227816062

Centisome position: 60.63

GC content: 38.34

Gene sequence:

>978_bases
GTGTCGACTATAGAGGACGTGGCGAAATTAGCGGGGTTATCAAGGACAACGGTTTCTAGGGTGATTAATAATCATCCATA
TGTTTCAGATGAGAAGAAAAAAAGGGTTCAATTAGCAATGAAGCATTTAGGCTTTGTTCCTAATTCTGCGGCGAGAAGGC
TTCGTAAACAAAAAACGGAAACAATTGCGGTGCTAGTTCCAAGGATTACAAATCCTTTCTTCAGTAGATTTATTGAAGCA
ATCGAGATTGCTGCTTCTGAACATAAATATAAACTGATTATTTGTCAAACAAGATATTTACCGGAAAAAGAGATGGAGTA
TTTACAATTATTATCTACGAAACAAGTGGATGGGATTATTCTATGTTCATTAGAAAATCCGTGGGAAGATGTAGAGCCAT
ACTTACAACACGGTCCAATCGTGTTATGTAATGAATATATTGAGGAAGCAAATATTCCAACAGTGAAGTTTGATCATGCG
CAAGGAGCATACATAGCTGCGAAGCATGTGTTAGAACAAGGATATCGTAATCTTATTTTTTGCCGTGGTAACGAAACCAA
AGTTGTTAGCCAACAGCGAAAAATGGGCTTTTTACGTGCCATAACGGAAAAGAGCCGCCAAGTAGAAGCGATCGATTTTC
TTGAAAACGCTTTCTCTTGGGAAGATGGCAAACGAATATTCCATGAAGTATTGAAAGACAAAAAAAATCCTACCGCGATT
TTGGCAGGAGGCGATGAGGTAGCAGCTGGAATTATTTCAGAGGCGAAACGCCATAATTGGAGCATTCCAGATGATCTCGC
TGTTATCGGTTTTGATAATCAAATTTTATCACAGATTACAGAACCAGGTATTACGACAATTGAACAGCCAATCGATGAGA
TGGCCCGAAAAGTTGTCGACCTAATGATGGATAAAATCCATACGAAAAATTATCGAAAAAAAGAATTGTATGAGTTTGAA
CTGGAGCTCTTGGTGTAA

Upstream 100 bases:

>100_bases
TATTAATATAGTAAAATCATAAGAAGCCGTATTGCAGTTTCCAATAATATACTATATAATCAATTTAAGAAAACGTTTTC
ATTCAAAGGGGGAGAATTTC

Downstream 100 bases:

>100_bases
GGTTCAACGATGAAGGATACGATGTTATTAGCCTAGTAGACTATGTCTGCTAGGTTTTTTTCTGTTCACAAACTACTATT
CTTCGTGAACGCAGTCATCA

Product: sugar-binding transcriptional regulator, LacI family

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 325; Mature: 324

Protein sequence:

>325_residues
MSTIEDVAKLAGLSRTTVSRVINNHPYVSDEKKKRVQLAMKHLGFVPNSAARRLRKQKTETIAVLVPRITNPFFSRFIEA
IEIAASEHKYKLIICQTRYLPEKEMEYLQLLSTKQVDGIILCSLENPWEDVEPYLQHGPIVLCNEYIEEANIPTVKFDHA
QGAYIAAKHVLEQGYRNLIFCRGNETKVVSQQRKMGFLRAITEKSRQVEAIDFLENAFSWEDGKRIFHEVLKDKKNPTAI
LAGGDEVAAGIISEAKRHNWSIPDDLAVIGFDNQILSQITEPGITTIEQPIDEMARKVVDLMMDKIHTKNYRKKELYEFE
LELLV

Sequences:

>Translated_325_residues
MSTIEDVAKLAGLSRTTVSRVINNHPYVSDEKKKRVQLAMKHLGFVPNSAARRLRKQKTETIAVLVPRITNPFFSRFIEA
IEIAASEHKYKLIICQTRYLPEKEMEYLQLLSTKQVDGIILCSLENPWEDVEPYLQHGPIVLCNEYIEEANIPTVKFDHA
QGAYIAAKHVLEQGYRNLIFCRGNETKVVSQQRKMGFLRAITEKSRQVEAIDFLENAFSWEDGKRIFHEVLKDKKNPTAI
LAGGDEVAAGIISEAKRHNWSIPDDLAVIGFDNQILSQITEPGITTIEQPIDEMARKVVDLMMDKIHTKNYRKKELYEFE
LELLV
>Mature_324_residues
STIEDVAKLAGLSRTTVSRVINNHPYVSDEKKKRVQLAMKHLGFVPNSAARRLRKQKTETIAVLVPRITNPFFSRFIEAI
EIAASEHKYKLIICQTRYLPEKEMEYLQLLSTKQVDGIILCSLENPWEDVEPYLQHGPIVLCNEYIEEANIPTVKFDHAQ
GAYIAAKHVLEQGYRNLIFCRGNETKVVSQQRKMGFLRAITEKSRQVEAIDFLENAFSWEDGKRIFHEVLKDKKNPTAIL
AGGDEVAAGIISEAKRHNWSIPDDLAVIGFDNQILSQITEPGITTIEQPIDEMARKVVDLMMDKIHTKNYRKKELYEFEL
ELLV

Specific function: Positively regulates the ntdABC operon and negatively regulates its own transcription. Binds to NTD to induce ntdABC transcription [H]

COG id: COG1609

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lacI-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1790369, Length=310, Percent_Identity=32.258064516129, Blast_Score=194, Evalue=5e-51,
Organism=Escherichia coli, GI1787948, Length=316, Percent_Identity=31.3291139240506, Blast_Score=169, Evalue=3e-43,
Organism=Escherichia coli, GI1790194, Length=318, Percent_Identity=27.3584905660377, Blast_Score=154, Evalue=9e-39,
Organism=Escherichia coli, GI1789202, Length=301, Percent_Identity=30.2325581395349, Blast_Score=147, Evalue=1e-36,
Organism=Escherichia coli, GI1788474, Length=304, Percent_Identity=27.9605263157895, Blast_Score=134, Evalue=1e-32,
Organism=Escherichia coli, GI48994940, Length=329, Percent_Identity=24.3161094224924, Blast_Score=119, Evalue=3e-28,
Organism=Escherichia coli, GI1789068, Length=327, Percent_Identity=23.5474006116208, Blast_Score=116, Evalue=2e-27,
Organism=Escherichia coli, GI1787580, Length=317, Percent_Identity=26.813880126183, Blast_Score=108, Evalue=5e-25,
Organism=Escherichia coli, GI1790715, Length=319, Percent_Identity=23.1974921630094, Blast_Score=108, Evalue=6e-25,
Organism=Escherichia coli, GI1786268, Length=311, Percent_Identity=24.7588424437299, Blast_Score=101, Evalue=5e-23,
Organism=Escherichia coli, GI1790689, Length=312, Percent_Identity=23.7179487179487, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI1786540, Length=325, Percent_Identity=24, Blast_Score=99, Evalue=3e-22,
Organism=Escherichia coli, GI1787906, Length=324, Percent_Identity=20.679012345679, Blast_Score=86, Evalue=5e-18,
Organism=Escherichia coli, GI1789456, Length=317, Percent_Identity=22.0820189274448, Blast_Score=67, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000843
- InterPro:   IPR010982
- InterPro:   IPR001761 [H]

Pfam domain/function: PF00356 LacI; PF00532 Peripla_BP_1 [H]

EC number: NA

Molecular weight: Translated: 37239; Mature: 37108

Theoretical pI: Translated: 7.01; Mature: 7.01

Prosite motif: PS50932 HTH_LACI_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTIEDVAKLAGLSRTTVSRVINNHPYVSDEKKKRVQLAMKHLGFVPNSAARRLRKQKTE
CCCHHHHHHHHCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHH
TIAVLVPRITNPFFSRFIEAIEIAASEHKYKLIICQTRYLPEKEMEYLQLLSTKQVDGII
EEEEEECHHCCHHHHHHHHHHHHHHCCCCEEEEEEECCCCCHHHHHHHHHHHHCCCCEEE
LCSLENPWEDVEPYLQHGPIVLCNEYIEEANIPTVKFDHAQGAYIAAKHVLEQGYRNLIF
EEECCCCHHHHHHHHHCCCEEEEHHHHHHCCCCEEEECCCCCHHHHHHHHHHHCCCEEEE
CRGNETKVVSQQRKMGFLRAITEKSRQVEAIDFLENAFSWEDGKRIFHEVLKDKKNPTAI
ECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCEE
LAGGDEVAAGIISEAKRHNWSIPDDLAVIGFDNQILSQITEPGITTIEQPIDEMARKVVD
EECCHHHHHHHHHHHHHCCCCCCCCEEEEECCHHHHHHHCCCCCHHHHHHHHHHHHHHHH
LMMDKIHTKNYRKKELYEFELELLV
HHHHHHHCCCCHHHHHHHHHHEEEC
>Mature Secondary Structure 
STIEDVAKLAGLSRTTVSRVINNHPYVSDEKKKRVQLAMKHLGFVPNSAARRLRKQKTE
CCHHHHHHHHCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHH
TIAVLVPRITNPFFSRFIEAIEIAASEHKYKLIICQTRYLPEKEMEYLQLLSTKQVDGII
EEEEEECHHCCHHHHHHHHHHHHHHCCCCEEEEEEECCCCCHHHHHHHHHHHHCCCCEEE
LCSLENPWEDVEPYLQHGPIVLCNEYIEEANIPTVKFDHAQGAYIAAKHVLEQGYRNLIF
EEECCCCHHHHHHHHHCCCEEEEHHHHHHCCCCEEEECCCCCHHHHHHHHHHHCCCEEEE
CRGNETKVVSQQRKMGFLRAITEKSRQVEAIDFLENAFSWEDGKRIFHEVLKDKKNPTAI
ECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCEE
LAGGDEVAAGIISEAKRHNWSIPDDLAVIGFDNQILSQITEPGITTIEQPIDEMARKVVD
EECCHHHHHHHHHHHHHCCCCCCCCEEEEECCHHHHHHHCCCCCHHHHHHHHHHHHHHHH
LMMDKIHTKNYRKKELYEFELELLV
HHHHHHHCCCCHHHHHHHHHHEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9579061; 9384377 [H]