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The map label for this gene is inlA [H]

Identifier: 227815825

GI number: 227815825

Start: 2949722

End: 2951302

Strand: Reverse

Name: inlA [H]

Synonym: BAMEG_3249

Alternate gene names: 227815825

Gene position: 2951302-2949722 (Counterclockwise)

Preceding gene: 227815826

Following gene: 227815824

Centisome position: 56.43

GC content: 32.45

Gene sequence:

>1581_bases
ATGCCAAATTTGAAATCTTTAACAGTTGCGAATGCGAAGATAAAAGATCCGTCGTTCTTTGCGAACTTAAAGCAATTAAA
TCATTTAGCTTTGCGTGGTAATGAATTTTCAGATGTAACACCACTTGTTAAGATGGATCATTTAGATTCTCTTGATTTAA
GTAATAATAAAATTACAAACGTTGCACCACTAATTGAAATGAAAAATGTAAAAAGTTTATATTTATCAGGTAACCAAATA
GAAGATGTAACAGCATTAGCGAAAATGGAACAACTAGATTATTTGAATTTAGCGAATAATAAAATTACGAATGTTGCTCC
ATTAAGCGCGTTAAAAAATGTAACATACTTGACTTTAGCTGGTAATCAAATTGAAGATATTAAACCGTTATATTCATTAC
CTTTAACAGACTTAGTATTAACACGTAATAAAGTTAAAGATTTATCCGGCATTGAGCAAATGAAGCAATTAGAAGAATTG
TGGATCGGGAAAAATGAAATAAAAGATGTTACTCCTCTAAGTAAGATGACACAGTTAAAACAATTACACCTACCTAACAA
TGAGTTAAAGGATATTACGCCATTATCAAGTCTAGTAAACTTACAAAAACTTGATTTAGAAGCAAATTATATTTCAGACT
TAACACCGGCTAGTAATTTGAAAAAGTTAGTATTCTTAAGTTTTGTTGCAAATGAAATTCGTGATGTTCGACCAGTGATA
GAACTAAGTAAAACAGCCTACATCAATGTTCAAAATCAAAAAGTATTTTTAGAGGAAACAGAAGTAAATAAAGAAGTAAA
AGTACCTATATACGAAAAAGACGGTAAAATCTCTACAAAAATTCGTTTGAAGGGCGAAGGTGGTACGTATAGTAACGATG
CAGTTAAGTGGAGTACACCAGGTGAGAAAGTATATGAATTTGGTGTGAAAGATCCATTTGCGGATACAGGAATCTTCTTT
ACGGGATCTGTCATTCAAAATGTGGTAGAAAGCAAAGCGGATAACACTTCTAAAGAAGACAATACTTCTAAAGAAGATGC
AAAAGTAGAAGTAGTGGAATTTAAAGATGTACCAAAAGGACATTGGTCAGAAGAAGCAATTCATTATTTAGCGAAAGAAA
ATATTTTCAAGGGATATGGAAATGGACAATTTGGATTTGGGGATAGTATTACTCGCGGACAAGTTGCGTCTTTAGTACAA
AGGTACTTGAAATTAGAAAATAAAGTAGAGCAGAAAGAGAGATTTACAGATACGAAAGGACATATGTTTGAGCAAGATAT
TGCTACAGTTGCGCAAGCTGGAATTATGCAAGGAGATGGTACTGGGGAGTTTCGTCCAGATGGAGTATTAACTCGATACG
AAATGTCTGTAGTATTATATAAAGTATTTCAGTTAAAAGAAGATGGAAATAATAAAGTGAACTTTAAAGATGTACCAACT
GGTCATTGGGCAGAAGGGTATGTGAAAGCGTTAGTGGATAATAACATATCAAAAGGTGATGGAAAAGAACGCTTTTTAGG
TGATGATTTTGTAACACGTGAACAATATGCACAGTTTTTATATAACGCAATAACGAAATAA

Upstream 100 bases:

>100_bases
AAAGATGTAAATACACCCGATTACGAAAGAAGAGTTATTACAAGTAAAGAATTTGTTTTTAAATACGAATGAGATTCTTG
ATTATAGTGCATTAAAATAT

Downstream 100 bases:

>100_bases
AAGATGAGAAAATACGTTATTCTTTCATTGGGAAAGAATAACGTATTTTTTATGTATAAAATGAACTAGTCAATATACAG
GAGTATAGACATATGAATGG

Product: internalin

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 526; Mature: 525

Protein sequence:

>526_residues
MPNLKSLTVANAKIKDPSFFANLKQLNHLALRGNEFSDVTPLVKMDHLDSLDLSNNKITNVAPLIEMKNVKSLYLSGNQI
EDVTALAKMEQLDYLNLANNKITNVAPLSALKNVTYLTLAGNQIEDIKPLYSLPLTDLVLTRNKVKDLSGIEQMKQLEEL
WIGKNEIKDVTPLSKMTQLKQLHLPNNELKDITPLSSLVNLQKLDLEANYISDLTPASNLKKLVFLSFVANEIRDVRPVI
ELSKTAYINVQNQKVFLEETEVNKEVKVPIYEKDGKISTKIRLKGEGGTYSNDAVKWSTPGEKVYEFGVKDPFADTGIFF
TGSVIQNVVESKADNTSKEDNTSKEDAKVEVVEFKDVPKGHWSEEAIHYLAKENIFKGYGNGQFGFGDSITRGQVASLVQ
RYLKLENKVEQKERFTDTKGHMFEQDIATVAQAGIMQGDGTGEFRPDGVLTRYEMSVVLYKVFQLKEDGNNKVNFKDVPT
GHWAEGYVKALVDNNISKGDGKERFLGDDFVTREQYAQFLYNAITK

Sequences:

>Translated_526_residues
MPNLKSLTVANAKIKDPSFFANLKQLNHLALRGNEFSDVTPLVKMDHLDSLDLSNNKITNVAPLIEMKNVKSLYLSGNQI
EDVTALAKMEQLDYLNLANNKITNVAPLSALKNVTYLTLAGNQIEDIKPLYSLPLTDLVLTRNKVKDLSGIEQMKQLEEL
WIGKNEIKDVTPLSKMTQLKQLHLPNNELKDITPLSSLVNLQKLDLEANYISDLTPASNLKKLVFLSFVANEIRDVRPVI
ELSKTAYINVQNQKVFLEETEVNKEVKVPIYEKDGKISTKIRLKGEGGTYSNDAVKWSTPGEKVYEFGVKDPFADTGIFF
TGSVIQNVVESKADNTSKEDNTSKEDAKVEVVEFKDVPKGHWSEEAIHYLAKENIFKGYGNGQFGFGDSITRGQVASLVQ
RYLKLENKVEQKERFTDTKGHMFEQDIATVAQAGIMQGDGTGEFRPDGVLTRYEMSVVLYKVFQLKEDGNNKVNFKDVPT
GHWAEGYVKALVDNNISKGDGKERFLGDDFVTREQYAQFLYNAITK
>Mature_525_residues
PNLKSLTVANAKIKDPSFFANLKQLNHLALRGNEFSDVTPLVKMDHLDSLDLSNNKITNVAPLIEMKNVKSLYLSGNQIE
DVTALAKMEQLDYLNLANNKITNVAPLSALKNVTYLTLAGNQIEDIKPLYSLPLTDLVLTRNKVKDLSGIEQMKQLEELW
IGKNEIKDVTPLSKMTQLKQLHLPNNELKDITPLSSLVNLQKLDLEANYISDLTPASNLKKLVFLSFVANEIRDVRPVIE
LSKTAYINVQNQKVFLEETEVNKEVKVPIYEKDGKISTKIRLKGEGGTYSNDAVKWSTPGEKVYEFGVKDPFADTGIFFT
GSVIQNVVESKADNTSKEDNTSKEDAKVEVVEFKDVPKGHWSEEAIHYLAKENIFKGYGNGQFGFGDSITRGQVASLVQR
YLKLENKVEQKERFTDTKGHMFEQDIATVAQAGIMQGDGTGEFRPDGVLTRYEMSVVLYKVFQLKEDGNNKVNFKDVPTG
HWAEGYVKALVDNNISKGDGKERFLGDDFVTREQYAQFLYNAITK

Specific function: Mediates the entry of Listeria monocytogenes into cells [H]

COG id: COG4886

COG function: function code S; Leucine-rich repeat (LRR) protein

Gene ontology:

Cell location: Secreted, cell wall; Peptidoglycan-anchor [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 14 LRR (leucine-rich) repeats [H]

Homologues:

Organism=Homo sapiens, GI21389483, Length=210, Percent_Identity=29.5238095238095, Blast_Score=85, Evalue=1e-16,
Organism=Homo sapiens, GI4506013, Length=225, Percent_Identity=28.8888888888889, Blast_Score=80, Evalue=5e-15,
Organism=Homo sapiens, GI55743114, Length=142, Percent_Identity=33.8028169014084, Blast_Score=67, Evalue=5e-11,
Organism=Homo sapiens, GI288541295, Length=283, Percent_Identity=28.6219081272085, Blast_Score=67, Evalue=5e-11,
Organism=Homo sapiens, GI288541297, Length=283, Percent_Identity=28.6219081272085, Blast_Score=67, Evalue=6e-11,
Organism=Homo sapiens, GI85986601, Length=249, Percent_Identity=27.3092369477912, Blast_Score=66, Evalue=1e-10,
Organism=Caenorhabditis elegans, GI17554124, Length=245, Percent_Identity=27.3469387755102, Blast_Score=82, Evalue=5e-16,
Organism=Caenorhabditis elegans, GI17531555, Length=220, Percent_Identity=28.6363636363636, Blast_Score=81, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17536161, Length=182, Percent_Identity=31.8681318681319, Blast_Score=80, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI71984630, Length=206, Percent_Identity=29.126213592233, Blast_Score=75, Evalue=1e-13,
Organism=Saccharomyces cerevisiae, GI6322655, Length=227, Percent_Identity=29.9559471365639, Blast_Score=68, Evalue=5e-12,
Organism=Drosophila melanogaster, GI21358617, Length=211, Percent_Identity=27.4881516587678, Blast_Score=74, Evalue=3e-13,
Organism=Drosophila melanogaster, GI24658034, Length=182, Percent_Identity=28.5714285714286, Blast_Score=69, Evalue=7e-12,
Organism=Drosophila melanogaster, GI221500776, Length=284, Percent_Identity=25.3521126760563, Blast_Score=66, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014755
- InterPro:   IPR019948
- InterPro:   IPR014756
- InterPro:   IPR001611
- InterPro:   IPR013378
- InterPro:   IPR019931
- InterPro:   IPR012569
- InterPro:   IPR001899 [H]

Pfam domain/function: PF09479 Flg_new; PF00746 Gram_pos_anchor; PF00560 LRR_1; PF08191 LRR_adjacent [H]

EC number: NA

Molecular weight: Translated: 59092; Mature: 58961

Theoretical pI: Translated: 5.80; Mature: 5.80

Prosite motif: PS01072 SLH_DOMAIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPNLKSLTVANAKIKDPSFFANLKQLNHLALRGNEFSDVTPLVKMDHLDSLDLSNNKITN
CCCCCCEEEECCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCHHHHCCCCCCCCCCCCCCC
VAPLIEMKNVKSLYLSGNQIEDVTALAKMEQLDYLNLANNKITNVAPLSALKNVTYLTLA
HHHHHHHCCCCEEEECCCCHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHCCCEEEEEE
GNQIEDIKPLYSLPLTDLVLTRNKVKDLSGIEQMKQLEELWIGKNEIKDVTPLSKMTQLK
CCCHHHCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCCHHHHHHHHH
QLHLPNNELKDITPLSSLVNLQKLDLEANYISDLTPASNLKKLVFLSFVANEIRDVRPVI
HHCCCCCCHHHCCHHHHHHHHHHHCCCHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHH
ELSKTAYINVQNQKVFLEETEVNKEVKVPIYEKDGKISTKIRLKGEGGTYSNDAVKWSTP
HHCCEEEEEEECCEEEEEECCCCCEEECEEEECCCCEEEEEEEEECCCCCCCCCEEECCC
GEKVYEFGVKDPFADTGIFFTGSVIQNVVESKADNTSKEDNTSKEDAKVEVVEFKDVPKG
CHHHHHCCCCCCCCCCCCEEEHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEEEECCCCCC
HWSEEAIHYLAKENIFKGYGNGQFGFGDSITRGQVASLVQRYLKLENKVEQKERFTDTKG
CCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
HMFEQDIATVAQAGIMQGDGTGEFRPDGVLTRYEMSVVLYKVFQLKEDGNNKVNFKDVPT
CHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEHHHHHHHHHHHHHHHCCCCCEECEEECCC
GHWAEGYVKALVDNNISKGDGKERFLGDDFVTREQYAQFLYNAITK
CCCHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
PNLKSLTVANAKIKDPSFFANLKQLNHLALRGNEFSDVTPLVKMDHLDSLDLSNNKITN
CCCCCEEEECCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCHHHHCCCCCCCCCCCCCCC
VAPLIEMKNVKSLYLSGNQIEDVTALAKMEQLDYLNLANNKITNVAPLSALKNVTYLTLA
HHHHHHHCCCCEEEECCCCHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHCCCEEEEEE
GNQIEDIKPLYSLPLTDLVLTRNKVKDLSGIEQMKQLEELWIGKNEIKDVTPLSKMTQLK
CCCHHHCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCCHHHHHHHHH
QLHLPNNELKDITPLSSLVNLQKLDLEANYISDLTPASNLKKLVFLSFVANEIRDVRPVI
HHCCCCCCHHHCCHHHHHHHHHHHCCCHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHH
ELSKTAYINVQNQKVFLEETEVNKEVKVPIYEKDGKISTKIRLKGEGGTYSNDAVKWSTP
HHCCEEEEEEECCEEEEEECCCCCEEECEEEECCCCEEEEEEEEECCCCCCCCCEEECCC
GEKVYEFGVKDPFADTGIFFTGSVIQNVVESKADNTSKEDNTSKEDAKVEVVEFKDVPKG
CHHHHHCCCCCCCCCCCCEEEHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEEEECCCCCC
HWSEEAIHYLAKENIFKGYGNGQFGFGDSITRGQVASLVQRYLKLENKVEQKERFTDTKG
CCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
HMFEQDIATVAQAGIMQGDGTGEFRPDGVLTRYEMSVVLYKVFQLKEDGNNKVNFKDVPT
CHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEHHHHHHHHHHHHHHHCCCCCEECEEECCC
GHWAEGYVKALVDNNISKGDGKERFLGDDFVTREQYAQFLYNAITK
CCCHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9541569 [H]