Click here to switch to the map view.

The map label for this gene is queC

Identifier: 227815813

GI number: 227815813

Start: 2939502

End: 2940164

Strand: Reverse

Name: queC

Synonym: BAMEG_3236

Alternate gene names: 227815813

Gene position: 2940164-2939502 (Counterclockwise)

Preceding gene: 227815815

Following gene: 227815812

Centisome position: 56.22

GC content: 36.95

Gene sequence:

>663_bases
ATGAAAAAAGAAAAGGCAGTTGTTGTTTTTAGTGGAGGACAAGATAGTACGACATGTTTATTTTGGGCAATAGAGCAGTT
TGCAGAAGTAGAGGCTGTAACGTTTAATTACAATCAACGTCATAAGCTAGAAATTGATTGTGCAGTGGAAATTGCAAAAG
AGCTAGGAATTAAACATACGGTACTAGATATGAGTCTATTAAATCAACTTGCTCCAAATGCGTTAACGAGAACGGATATG
GAGATTACACATGAAGAAGGTGAATTACCATCGACGTTTGTAGATGGACGAAATTTACTATTCTTATCATTTGCTGCTGT
ATTAGCAAAACAAGTTGGAGCACGTCATATTGTAACGGGTGTATGTGAAACTGATTTTAGTGGTTATCCAGATTGCCGTG
ACGTGTTTGTGAAATCGTTAAACGTTACTTTAAATTTATCGATGGATTATCCGTTTGTGATTCATACACCACTTATGTGG
ATTGATAAAGCGGAAACATGGAAATTATCAGATGAACTTGGAGCATTCGAGTTTGTTAGAGAGAAAACATTAACATGTTA
TAACGGAATCATTGGTGATGGTTGCGGTGAATGTCCAGCATGTCAACTTCGTAAAGCAGGATTAGATACGTATCTACAAG
AACGCGAAGGAGCGAGTAACTAA

Upstream 100 bases:

>100_bases
TGGAAACAACAATATCTTTAGGTATTGTTTTGTTTTTTTATTGTGACAGTTCAAGAACGTTCTTTCTTCTTATTCGTAGT
AGAGAAGGAGAATGAGTGAA

Downstream 100 bases:

>100_bases
TGGATAATTTCTTTGGATTTCGCATCGTAGAAAATTTGCAAAAAATGGACAAGGATATTCAACGTAAACAGCTCAAATAT
CATAATAAAAGAGTAATGGT

Product: exsB protein

Products: NA

Alternate protein names: 7-cyano-7-carbaguanine synthase; PreQ(0) synthase; Queuosine biosynthesis protein queC

Number of amino acids: Translated: 220; Mature: 220

Protein sequence:

>220_residues
MKKEKAVVVFSGGQDSTTCLFWAIEQFAEVEAVTFNYNQRHKLEIDCAVEIAKELGIKHTVLDMSLLNQLAPNALTRTDM
EITHEEGELPSTFVDGRNLLFLSFAAVLAKQVGARHIVTGVCETDFSGYPDCRDVFVKSLNVTLNLSMDYPFVIHTPLMW
IDKAETWKLSDELGAFEFVREKTLTCYNGIIGDGCGECPACQLRKAGLDTYLQEREGASN

Sequences:

>Translated_220_residues
MKKEKAVVVFSGGQDSTTCLFWAIEQFAEVEAVTFNYNQRHKLEIDCAVEIAKELGIKHTVLDMSLLNQLAPNALTRTDM
EITHEEGELPSTFVDGRNLLFLSFAAVLAKQVGARHIVTGVCETDFSGYPDCRDVFVKSLNVTLNLSMDYPFVIHTPLMW
IDKAETWKLSDELGAFEFVREKTLTCYNGIIGDGCGECPACQLRKAGLDTYLQEREGASN
>Mature_220_residues
MKKEKAVVVFSGGQDSTTCLFWAIEQFAEVEAVTFNYNQRHKLEIDCAVEIAKELGIKHTVLDMSLLNQLAPNALTRTDM
EITHEEGELPSTFVDGRNLLFLSFAAVLAKQVGARHIVTGVCETDFSGYPDCRDVFVKSLNVTLNLSMDYPFVIHTPLMW
IDKAETWKLSDELGAFEFVREKTLTCYNGIIGDGCGECPACQLRKAGLDTYLQEREGASN

Specific function: Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))

COG id: COG0603

COG function: function code R; Predicted PP-loop superfamily ATPase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the queC family

Homologues:

Organism=Escherichia coli, GI1786648, Length=216, Percent_Identity=57.8703703703704, Blast_Score=258, Evalue=3e-70,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): QUEC_BACAA (C3P4F6)

Other databases:

- EMBL:   CP001598
- RefSeq:   YP_002865853.1
- ProteinModelPortal:   C3P4F6
- SMR:   C3P4F6
- EnsemblBacteria:   EBBACT00000125396
- GeneID:   7849584
- GenomeReviews:   CP001598_GR
- KEGG:   bai:BAA_1427
- GeneTree:   EBGT00050000002556
- ProtClustDB:   CLSK916200
- HAMAP:   MF_01633_B
- InterPro:   IPR018317
- InterPro:   IPR014729
- Gene3D:   G3DSA:3.40.50.620
- PIRSF:   PIRSF006293
- TIGRFAMs:   TIGR00364

Pfam domain/function: PF06508 ExsB

EC number: NA

Molecular weight: Translated: 24541; Mature: 24541

Theoretical pI: Translated: 4.58; Mature: 4.58

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.6 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
5.9 %Cys+Met (Translated Protein)
3.6 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
5.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKEKAVVVFSGGQDSTTCLFWAIEQFAEVEAVTFNYNQRHKLEIDCAVEIAKELGIKHT
CCCCCEEEEEECCCCCCHHHHHHHHHHHCEEEEEECCCCCEEEEHHHHHHHHHHCCCCHH
VLDMSLLNQLAPNALTRTDMEITHEEGELPSTFVDGRNLLFLSFAAVLAKQVGARHIVTG
HHHHHHHHHHCCCHHCCCCCEEECCCCCCCCEECCCCCHHHHHHHHHHHHHHCCHHHHHE
VCETDFSGYPDCRDVFVKSLNVTLNLSMDYPFVIHTPLMWIDKAETWKLSDELGAFEFVR
ECCCCCCCCCCHHHHHHHHCCEEEEEECCCCEEEECCEEEECCCCCEECHHHHHHHHHHH
EKTLTCYNGIIGDGCGECPACQLRKAGLDTYLQEREGASN
HHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MKKEKAVVVFSGGQDSTTCLFWAIEQFAEVEAVTFNYNQRHKLEIDCAVEIAKELGIKHT
CCCCCEEEEEECCCCCCHHHHHHHHHHHCEEEEEECCCCCEEEEHHHHHHHHHHCCCCHH
VLDMSLLNQLAPNALTRTDMEITHEEGELPSTFVDGRNLLFLSFAAVLAKQVGARHIVTG
HHHHHHHHHHCCCHHCCCCCEEECCCCCCCCEECCCCCHHHHHHHHHHHHHHCCHHHHHE
VCETDFSGYPDCRDVFVKSLNVTLNLSMDYPFVIHTPLMWIDKAETWKLSDELGAFEFVR
ECCCCCCCCCCHHHHHHHHCCEEEEEECCCCEEEECCEEEECCCCCEECHHHHHHHHHHH
EKTLTCYNGIIGDGCGECPACQLRKAGLDTYLQEREGASN
HHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA