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The map label for this gene is bla1 [H]

Identifier: 227814685

GI number: 227814685

Start: 1909572

End: 1910402

Strand: Reverse

Name: bla1 [H]

Synonym: BAMEG_2095

Alternate gene names: 227814685

Gene position: 1910402-1909572 (Counterclockwise)

Preceding gene: 227814686

Following gene: 227814683

Centisome position: 36.53

GC content: 39.83

Gene sequence:

>831_bases
TTGCAAGTTGAAGCGAAAGAAAAGACTGGACAAGTGAAACATAAAAATCAGGCGACGCATAAAGAGTTCTCTCAACTTGA
GAAAAAATTTGATGCTCGATTAGGTGTATATGCGATTGATACTGGTACAAATCAAACAATCGCTTATCGACCTAACGAAA
GGTTTGCCTTTGCATCAACTTACAAGGCTTTAGCGGCAGGGGTATTACTGCAACAGAACTCTACTAAGAAATTAGATGAA
GTTATTACTTATACGAAAGAAGACTTAGTGGATTATTCACCTGTTACAGAGAAACATGTAGATACTGGAATGACACTAGG
AGAAATTGCGGAGGCTGCTGTTCGTTACAGTGATAATACTGCAGGGAACATTTTATTTCATAAAATAGGCGGACCGAAAG
GATATGAAAAAGCGCTTAGACAGATGGGGGACCGGGTTACTATGTCTGATCGTTTTGAAACAGAATTAAACGAGGCTATT
CCAGGAGACATTCGTGACACCAGTACAGCGAAAGCAATTGCTACGAATCTTAAAGCTTTTACGGCCGGAAATGCGCTTCC
AAATCATAAACGTAACATTCTTACAAAGTGGATGAAAGGAAATGCTACAGGAGACAAACTTATTCGTGCAGGTGTGCCTA
CTAACTGGGTAGTTGCAGATAAATCAGGAGCTGGAAGTTACGGGACACGAAATGATATTGCTATCGTTTGGCCACCAAAT
AGAGCACCTATTATCATCGCAATTTTATCTAGTAAAGATGAAAAAGGGGCTACCTATGATAATCAACTCATTGCAGAGGC
GGCTGAAGTTATAGTTAATGCTTTTAGGTGA

Upstream 100 bases:

>100_bases
AATGATAGTTTTGAAAAACAAGAAAATGCTAAAAATAGGGATGTGTGTTGGTATATTAGGTTTAAGTATTACAAGCCTAG
TAACTTTTACAGGAGGTGCA

Downstream 100 bases:

>100_bases
TAATCTCTCAATTCTTTATGTAATGTAATTGAAAATATGAACTTGGAAAGCGATTCTTTTTAATATGAAAAGAATCGCTT
TTTTGTATTCCTAATACATT

Product: beta-lactamase Bla1

Products: NA

Alternate protein names: Beta-lactamase I; Penicillinase [H]

Number of amino acids: Translated: 276; Mature: 276

Protein sequence:

>276_residues
MQVEAKEKTGQVKHKNQATHKEFSQLEKKFDARLGVYAIDTGTNQTIAYRPNERFAFASTYKALAAGVLLQQNSTKKLDE
VITYTKEDLVDYSPVTEKHVDTGMTLGEIAEAAVRYSDNTAGNILFHKIGGPKGYEKALRQMGDRVTMSDRFETELNEAI
PGDIRDTSTAKAIATNLKAFTAGNALPNHKRNILTKWMKGNATGDKLIRAGVPTNWVVADKSGAGSYGTRNDIAIVWPPN
RAPIIIAILSSKDEKGATYDNQLIAEAAEVIVNAFR

Sequences:

>Translated_276_residues
MQVEAKEKTGQVKHKNQATHKEFSQLEKKFDARLGVYAIDTGTNQTIAYRPNERFAFASTYKALAAGVLLQQNSTKKLDE
VITYTKEDLVDYSPVTEKHVDTGMTLGEIAEAAVRYSDNTAGNILFHKIGGPKGYEKALRQMGDRVTMSDRFETELNEAI
PGDIRDTSTAKAIATNLKAFTAGNALPNHKRNILTKWMKGNATGDKLIRAGVPTNWVVADKSGAGSYGTRNDIAIVWPPN
RAPIIIAILSSKDEKGATYDNQLIAEAAEVIVNAFR
>Mature_276_residues
MQVEAKEKTGQVKHKNQATHKEFSQLEKKFDARLGVYAIDTGTNQTIAYRPNERFAFASTYKALAAGVLLQQNSTKKLDE
VITYTKEDLVDYSPVTEKHVDTGMTLGEIAEAAVRYSDNTAGNILFHKIGGPKGYEKALRQMGDRVTMSDRFETELNEAI
PGDIRDTSTAKAIATNLKAFTAGNALPNHKRNILTKWMKGNATGDKLIRAGVPTNWVVADKSGAGSYGTRNDIAIVWPPN
RAPIIIAILSSKDEKGATYDNQLIAEAAEVIVNAFR

Specific function: Acts preferentially on penicillins [H]

COG id: COG2367

COG function: function code V; Beta-lactamase class A

Gene ontology:

Cell location: Secreted [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-A beta-lactamase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012338
- InterPro:   IPR001466
- InterPro:   IPR000871 [H]

Pfam domain/function: PF00144 Beta-lactamase [H]

EC number: =3.5.2.6 [H]

Molecular weight: Translated: 30277; Mature: 30277

Theoretical pI: Translated: 9.53; Mature: 9.53

Prosite motif: PS00146 BETA_LACTAMASE_A

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQVEAKEKTGQVKHKNQATHKEFSQLEKKFDARLGVYAIDTGTNQTIAYRPNERFAFAST
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCEEEEECCCCCEEEECCCCCEEHHHH
YKALAAGVLLQQNSTKKLDEVITYTKEDLVDYSPVTEKHVDTGMTLGEIAEAAVRYSDNT
HHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHCCCCHHHHHHHHHHCCCCC
AGNILFHKIGGPKGYEKALRQMGDRVTMSDRFETELNEAIPGDIRDTSTAKAIATNLKAF
CCCEEEEECCCCCHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHH
TAGNALPNHKRNILTKWMKGNATGDKLIRAGVPTNWVVADKSGAGSYGTRNDIAIVWPPN
CCCCCCCCHHHHHHHHHHCCCCCHHHHEECCCCCCEEEECCCCCCCCCCCCCEEEEECCC
RAPIIIAILSSKDEKGATYDNQLIAEAAEVIVNAFR
CCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MQVEAKEKTGQVKHKNQATHKEFSQLEKKFDARLGVYAIDTGTNQTIAYRPNERFAFAST
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCEEEEECCCCCEEEECCCCCEEHHHH
YKALAAGVLLQQNSTKKLDEVITYTKEDLVDYSPVTEKHVDTGMTLGEIAEAAVRYSDNT
HHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHCCCCHHHHHHHHHHCCCCC
AGNILFHKIGGPKGYEKALRQMGDRVTMSDRFETELNEAIPGDIRDTSTAKAIATNLKAF
CCCEEEEECCCCCHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHH
TAGNALPNHKRNILTKWMKGNATGDKLIRAGVPTNWVVADKSGAGSYGTRNDIAIVWPPN
CCCCCCCCHHHHHHHHHHCCCCCHHHHEECCCCCCEEEECCCCCCCCCCCCCEEEEECCC
RAPIIIAILSSKDEKGATYDNQLIAEAAEVIVNAFR
CCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2991192 [H]