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The map label for this gene is vat [H]

Identifier: 227814554

GI number: 227814554

Start: 1790524

End: 1791156

Strand: Reverse

Name: vat [H]

Synonym: BAMEG_1963

Alternate gene names: 227814554

Gene position: 1791156-1790524 (Counterclockwise)

Preceding gene: 227814555

Following gene: 227814553

Centisome position: 34.25

GC content: 33.65

Gene sequence:

>633_bases
ATGAATCCTAATCCAAATGTTAAATACCCTATTGAAGGAAATCAAAACGTCCATTTTATAAAAAATACAATAACAAAAGC
TAATATACTCGTTGGAGACTATTCATATTATGATGCGAAAGATGGAGAAACATTTGAAGATCGAGTATTACATCATTATG
AATTTCTTGGAGATCGCCTTATTATTGGAAAGTTTTGTTGTATTGCAAGTGGAGTTACCTTTATTATGAACGGAGCGAAT
CATCGGATGGATGGGTTTTCGGCATATCCATTTAATATATTTGGAAATGGGTGGGAGAAGTATACACCTAATTTGTCTGA
TTTACCTTACAAAGGCGATACAGTTATAGGAAATGACGTTTGGATCGGTATGGATGCAACCATTATGCCTGGAATAAAAA
TAGGGGATGGTGCAATAATAGCAGCTAAATCTGTTGTGACGAGAGACGTCGCACCATATACAATTGTTGGCGGAAACCCT
GCAAATAAAATAAGGGAGAGATTTTCAAATGCAATAATAGAAGAATTATTACAAATTCAATGGTGGCATTTTGATATTGA
AAAAATAACTGAAAATATAGGTGCTATTGTACAAGGAAATATAGAGCCATTAAGAAAGCTAAAAAGGGAATAA

Upstream 100 bases:

>100_bases
CTATTTATAATTGGATTATTGTTTATTTTACCTATATACAATTTAAAGCCAACGATAGTAATAGAAAGTGAAATAAGTGG
TAAAGGAAGTGCTATACAAA

Downstream 100 bases:

>100_bases
AAAATGCATAACAAAGAGTATCATACCTCCGAATTTTGTTAATGATAATAGAACAAGGAGGTGTGATACTATGGCACAAG
ACGTTTTATGTGAAGTAAAC

Product: acetyltransferase, CYSE/LACA/LPXA/NODL family

Products: CoA; acetylmaltose [C]

Alternate protein names: NA

Number of amino acids: Translated: 210; Mature: 210

Protein sequence:

>210_residues
MNPNPNVKYPIEGNQNVHFIKNTITKANILVGDYSYYDAKDGETFEDRVLHHYEFLGDRLIIGKFCCIASGVTFIMNGAN
HRMDGFSAYPFNIFGNGWEKYTPNLSDLPYKGDTVIGNDVWIGMDATIMPGIKIGDGAIIAAKSVVTRDVAPYTIVGGNP
ANKIRERFSNAIIEELLQIQWWHFDIEKITENIGAIVQGNIEPLRKLKRE

Sequences:

>Translated_210_residues
MNPNPNVKYPIEGNQNVHFIKNTITKANILVGDYSYYDAKDGETFEDRVLHHYEFLGDRLIIGKFCCIASGVTFIMNGAN
HRMDGFSAYPFNIFGNGWEKYTPNLSDLPYKGDTVIGNDVWIGMDATIMPGIKIGDGAIIAAKSVVTRDVAPYTIVGGNP
ANKIRERFSNAIIEELLQIQWWHFDIEKITENIGAIVQGNIEPLRKLKRE
>Mature_210_residues
MNPNPNVKYPIEGNQNVHFIKNTITKANILVGDYSYYDAKDGETFEDRVLHHYEFLGDRLIIGKFCCIASGVTFIMNGAN
HRMDGFSAYPFNIFGNGWEKYTPNLSDLPYKGDTVIGNDVWIGMDATIMPGIKIGDGAIIAAKSVVTRDVAPYTIVGGNP
ANKIRERFSNAIIEELLQIQWWHFDIEKITENIGAIVQGNIEPLRKLKRE

Specific function: Inactivates the A compounds of virginiamycin-like antibiotics, thus providing resistance to these antibiotics [H]

COG id: COG0110

COG function: function code R; Acetyltransferase (isoleucine patch superfamily)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the transferase hexapeptide repeat family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001451
- InterPro:   IPR018357
- InterPro:   IPR011004 [H]

Pfam domain/function: PF00132 Hexapep [H]

EC number: 2.3.1.79 [C]

Molecular weight: Translated: 23612; Mature: 23612

Theoretical pI: Translated: 6.02; Mature: 6.02

Prosite motif: PS00101 HEXAPEP_TRANSFERASES

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNPNPNVKYPIEGNQNVHFIKNTITKANILVGDYSYYDAKDGETFEDRVLHHYEFLGDRL
CCCCCCEEEECCCCCCEEEEECCCCEEEEEEECCCEECCCCCCCHHHHHHHHHHHHCCCH
IIGKFCCIASGVTFIMNGANHRMDGFSAYPFNIFGNGWEKYTPNLSDLPYKGDTVIGNDV
HHHHHHHHHCCCEEEECCCCCCCCCCEECCEEEECCCHHHCCCCCCCCCCCCCEEECCCE
WIGMDATIMPGIKIGDGAIIAAKSVVTRDVAPYTIVGGNPANKIRERFSNAIIEELLQIQ
EECCCCEECCCEEECCCEEEEHHHHHHHCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHH
WWHFDIEKITENIGAIVQGNIEPLRKLKRE
HHEEEHHHHHHHHCEEEECCHHHHHHHHCC
>Mature Secondary Structure
MNPNPNVKYPIEGNQNVHFIKNTITKANILVGDYSYYDAKDGETFEDRVLHHYEFLGDRL
CCCCCCEEEECCCCCCEEEEECCCCEEEEEEECCCEECCCCCCCHHHHHHHHHHHHCCCH
IIGKFCCIASGVTFIMNGANHRMDGFSAYPFNIFGNGWEKYTPNLSDLPYKGDTVIGNDV
HHHHHHHHHCCCEEEECCCCCCCCCCEECCEEEECCCHHHCCCCCCCCCCCCCEEECCCE
WIGMDATIMPGIKIGDGAIIAAKSVVTRDVAPYTIVGGNPANKIRERFSNAIIEELLQIQ
EECCCCEECCCEEECCCEEEEHHHHHHHCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHH
WWHFDIEKITENIGAIVQGNIEPLRKLKRE
HHEEEHHHHHHHHCEEEECCHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: 0.20 {glucose} 0.11 {maltose}

Km value (mM): 62 {glucose}} 90 {maltose}} 0.018 {acetyl-CoA}} 40 {triethanolamine}} [C]

Substrates: Acetyl-CoA; maltose [C]

Specific reaction: Acetyl-CoA + maltose = CoA + acetylmaltose [C]

General reaction: Acyl group transfer [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8344533; 3149758 [H]