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The map label for this gene is adP1 [C]

Identifier: 227814524

GI number: 227814524

Start: 1757242

End: 1758408

Strand: Reverse

Name: adP1 [C]

Synonym: BAMEG_1932

Alternate gene names: 227814524

Gene position: 1758408-1757242 (Counterclockwise)

Preceding gene: 227814526

Following gene: 227814523

Centisome position: 33.62

GC content: 40.19

Gene sequence:

>1167_bases
ATGAAAACATGCAGTAAAATTACATGTGCAAGTCTATCACTTTTAATAGCTGGAAGTTCCCTGTTATACATAACACCAGC
CTCAATTGTAAAAGCAGAACCCACGCAAAATGTATCTAGTTCGTTACAAACAAGTAATCAAAGCGATCGTACTTCCGTTA
AGAAAGCAATGCGGGATTCACTCCAACTTGGATACCCTGGAATACTCGCTCAAATTTCTAAGGGTGGTAAAAATTGGAGC
TATGCGGCCGGGATAGCGGATCTGAGAACCAAGAAGCAGATGAAAACAGATTTTCGCTTTCGTATTGGCAGTACGACGAA
GACATTCATTGCAACAGTTCTACTTCAATTGGCTGGAGAGAACCGCTTGAATCTAGATGACTCCATCGAAAAATGGCTAC
CTGGCGTCATTCAAGGAAACGGATATGATGCTAACCAGATTACGATTCGGCAAATATTGAATCATACAAGTGGGATTGCT
GAATACTTAAAGTCAAAAGACTATGATATTATGGATACAAAAAAATTGTATACGGCTGAAGAATTAGTAAAGATGGGAAT
TTCTCTTCCACCAGACTTTGCTCCAGGTAAGGGCTGGTCTTATTCAAACACAGGATACGTAATACTGGGTATCCTTATTG
AAAAAGTAACTGGAAACAGCTATGCGGAAGAGGTTGAAAATCGGATTGTTGAACCGCTCGAATTGTCGAATACATTCCTA
CCTGGTAATTCAACTGTTATTCCAGGTACCAAACATGCCCGTGGATATGAAAGATATGACGGAGAAAGTGAGCTAAAAGA
CGTTACTTATTCTTACCCAGGTAGCTCGGATGGAGATATGATTTCCACTGCTGACGACTTAAACAAATTCTTCTCTTACT
TACTCAGTGGCAAATTACTGAAGGAACAGCAACTAAAACAAATGCTTACTACAGTTCCTACAGGAATTGCTGAAATCGGC
AGATATGGTCTTGGAATCTATGAAACTAAACTTCCAAACGGTGTCTCGATATGGGGACACGCAGGTGCCTCTCCAGGGTT
TTCTACTTTTGCTGGAGGCACACTTGGAGGCAAGCATACAGTAGCCATCAATTTGAATGGCCATGAAACTAGTTATAGTC
CTTCTGATCCTTTTAAAAATATTTTACTTGCTGAATTTAGCAAGTAG

Upstream 100 bases:

>100_bases
AATTATGACTTTTTTGTCATTGTTGGAGATGATAGCTGTGTGATTAATACGAAACAGCAAGCAACTAGCTTTACAATTTA
AATAAAGGAGAGGATGCTTT

Downstream 100 bases:

>100_bases
TCAAAAAGGAAAGTAAAGTAAATCTTTTTATAGATAAAAATATACCTTTTTGGTTCAAAAAAATAACCTCTTTTTAAAAT
TTTTTTGAAATTAAGGTGGT

Product: alkaline D-peptidase

Products: NA

Alternate protein names: DD-carboxypeptidase; DD-peptidase [H]

Number of amino acids: Translated: 388; Mature: 388

Protein sequence:

>388_residues
MKTCSKITCASLSLLIAGSSLLYITPASIVKAEPTQNVSSSLQTSNQSDRTSVKKAMRDSLQLGYPGILAQISKGGKNWS
YAAGIADLRTKKQMKTDFRFRIGSTTKTFIATVLLQLAGENRLNLDDSIEKWLPGVIQGNGYDANQITIRQILNHTSGIA
EYLKSKDYDIMDTKKLYTAEELVKMGISLPPDFAPGKGWSYSNTGYVILGILIEKVTGNSYAEEVENRIVEPLELSNTFL
PGNSTVIPGTKHARGYERYDGESELKDVTYSYPGSSDGDMISTADDLNKFFSYLLSGKLLKEQQLKQMLTTVPTGIAEIG
RYGLGIYETKLPNGVSIWGHAGASPGFSTFAGGTLGGKHTVAINLNGHETSYSPSDPFKNILLAEFSK

Sequences:

>Translated_388_residues
MKTCSKITCASLSLLIAGSSLLYITPASIVKAEPTQNVSSSLQTSNQSDRTSVKKAMRDSLQLGYPGILAQISKGGKNWS
YAAGIADLRTKKQMKTDFRFRIGSTTKTFIATVLLQLAGENRLNLDDSIEKWLPGVIQGNGYDANQITIRQILNHTSGIA
EYLKSKDYDIMDTKKLYTAEELVKMGISLPPDFAPGKGWSYSNTGYVILGILIEKVTGNSYAEEVENRIVEPLELSNTFL
PGNSTVIPGTKHARGYERYDGESELKDVTYSYPGSSDGDMISTADDLNKFFSYLLSGKLLKEQQLKQMLTTVPTGIAEIG
RYGLGIYETKLPNGVSIWGHAGASPGFSTFAGGTLGGKHTVAINLNGHETSYSPSDPFKNILLAEFSK
>Mature_388_residues
MKTCSKITCASLSLLIAGSSLLYITPASIVKAEPTQNVSSSLQTSNQSDRTSVKKAMRDSLQLGYPGILAQISKGGKNWS
YAAGIADLRTKKQMKTDFRFRIGSTTKTFIATVLLQLAGENRLNLDDSIEKWLPGVIQGNGYDANQITIRQILNHTSGIA
EYLKSKDYDIMDTKKLYTAEELVKMGISLPPDFAPGKGWSYSNTGYVILGILIEKVTGNSYAEEVENRIVEPLELSNTFL
PGNSTVIPGTKHARGYERYDGESELKDVTYSYPGSSDGDMISTADDLNKFFSYLLSGKLLKEQQLKQMLTTVPTGIAEIG
RYGLGIYETKLPNGVSIWGHAGASPGFSTFAGGTLGGKHTVAINLNGHETSYSPSDPFKNILLAEFSK

Specific function: Catalyzes distinct carboxypeptidation and transpeptidation reactions during the last stages of wall peptidoglycan synthesis. Mistaking a beta-lactam antibiotic molecule for a normal substrate (i.e., a D-alanyl-D-alanine- terminated peptide), it becomes im

COG id: COG1680

COG function: function code V; Beta-lactamase class C and other penicillin binding proteins

Gene ontology:

Cell location: Secreted [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S12 family [H]

Homologues:

Organism=Escherichia coli, GI1790593, Length=247, Percent_Identity=24.2914979757085, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI87082101, Length=253, Percent_Identity=25.6916996047431, Blast_Score=63, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI115533026, Length=340, Percent_Identity=25.5882352941176, Blast_Score=76, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI17550934, Length=191, Percent_Identity=30.3664921465969, Blast_Score=75, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI17565630, Length=313, Percent_Identity=26.8370607028754, Blast_Score=65, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012338
- InterPro:   IPR001466 [H]

Pfam domain/function: PF00144 Beta-lactamase [H]

EC number: =3.4.16.4 [H]

Molecular weight: Translated: 42191; Mature: 42191

Theoretical pI: Translated: 8.51; Mature: 8.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTCSKITCASLSLLIAGSSLLYITPASIVKAEPTQNVSSSLQTSNQSDRTSVKKAMRDS
CCCCHHHHHHHHHHHHCCCCEEEECCHHHEECCCCHHHHHHHHCCCCHHHHHHHHHHHHH
LQLGYPGILAQISKGGKNWSYAAGIADLRTKKQMKTDFRFRIGSTTKTFIATVLLQLAGE
HHCCCCHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCEEEECCCHHHHHHHHHHHHHCC
NRLNLDDSIEKWLPGVIQGNGYDANQITIRQILNHTSGIAEYLKSKDYDIMDTKKLYTAE
CCCCCCHHHHHHCCCEEECCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHH
ELVKMGISLPPDFAPGKGWSYSNTGYVILGILIEKVTGNSYAEEVENRIVEPLELSNTFL
HHHHHCCCCCCCCCCCCCCCCCCCCCEEEEEHHHHHCCCHHHHHHHHHCCCCHHHCCEEC
PGNSTVIPGTKHARGYERYDGESELKDVTYSYPGSSDGDMISTADDLNKFFSYLLSGKLL
CCCCEECCCCCCCCCCHHCCCHHHHHHCEEECCCCCCCCCCCCHHHHHHHHHHHHCCHHH
KEQQLKQMLTTVPTGIAEIGRYGLGIYETKLPNGVSIWGHAGASPGFSTFAGGTLGGKHT
HHHHHHHHHHHHCCCHHHHHHHCCCEEEECCCCCCEEEECCCCCCCCHHHCCCCCCCCEE
VAINLNGHETSYSPSDPFKNILLAEFSK
EEEEECCCCCCCCCCCHHHHHHHHHCCC
>Mature Secondary Structure
MKTCSKITCASLSLLIAGSSLLYITPASIVKAEPTQNVSSSLQTSNQSDRTSVKKAMRDS
CCCCHHHHHHHHHHHHCCCCEEEECCHHHEECCCCHHHHHHHHCCCCHHHHHHHHHHHHH
LQLGYPGILAQISKGGKNWSYAAGIADLRTKKQMKTDFRFRIGSTTKTFIATVLLQLAGE
HHCCCCHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCEEEECCCHHHHHHHHHHHHHCC
NRLNLDDSIEKWLPGVIQGNGYDANQITIRQILNHTSGIAEYLKSKDYDIMDTKKLYTAE
CCCCCCHHHHHHCCCEEECCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHH
ELVKMGISLPPDFAPGKGWSYSNTGYVILGILIEKVTGNSYAEEVENRIVEPLELSNTFL
HHHHHCCCCCCCCCCCCCCCCCCCCCEEEEEHHHHHCCCHHHHHHHHHCCCCHHHCCEEC
PGNSTVIPGTKHARGYERYDGESELKDVTYSYPGSSDGDMISTADDLNKFFSYLLSGKLL
CCCCEECCCCCCCCCCHHCCCHHHHHHCEEECCCCCCCCCCCCHHHHHHHHHHHHCCHHH
KEQQLKQMLTTVPTGIAEIGRYGLGIYETKLPNGVSIWGHAGASPGFSTFAGGTLGGKHT
HHHHHHHHHHHHCCCHHHHHHHCCCEEEECCCCCCEEEECCCCCCCCHHHCCCCCCCCEE
VAINLNGHETSYSPSDPFKNILLAEFSK
EEEEECCCCCCCCCCCHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 3830154; 7925404; 3030739; 2175384; 2386365; 3997832; 7490745 [H]