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The map label for this gene is walR [H]

Identifier: 227814328

GI number: 227814328

Start: 1584685

End: 1585284

Strand: Direct

Name: walR [H]

Synonym: BAMEG_1736

Alternate gene names: 227814328

Gene position: 1584685-1585284 (Clockwise)

Preceding gene: 227814326

Following gene: 227814329

Centisome position: 30.3

GC content: 31.17

Gene sequence:

>600_bases
ATGAAAGTATTAATCGCAGATGATGAACAAGATATGCTAAGGATTTTAAAAGCTTATTTTGAGAAAGAAGGCTTCGAAGT
TTTCTTAGCGAAAGATGGAGAAGAAGCACTTCAAATATTTTATGATGAAAAAATTGATTTAGCTATTTTAGATTGGATGA
TGCCGAAACATAGCGGTATTACTGTTTGTCAGGAAATAAAGAAAAACTCAAGCGTAAAAGTATTAATGCTCACGGCGAAA
AGTGAAAGCGAAGATGAATTAGCAGCTCTTCAAAGCGGGGCAGATGAGTACGTAAAAAAAACATTTCATCCAGGTGTACT
CATTACTCGAGCGAAAAAGCTAATACAGCACGATGATGTCATTCAAGTTCAAGATTTGAAAATTGATTTTACGAAAAATA
AAGTTTATAAAAATGACAAGGAATTAGATATTACAAAAACAGAGCTAGAATTAATAAAATGTTTTTTAAATCATAAAGGG
ATGATTTTAACTCGTAAAAAATTGTTAGATATCGTATGGGGATTTGACTATTTTGGAGAAGAGCGAACTGTTGATACACA
TGTAAGGAGATTACGAAAAAAATTGGAGAAAATATTATAA

Upstream 100 bases:

>100_bases
TATACCCTTAACTGGTTCAAATATTTTTCTGTCACATACATGTAACAAAGAAGTTGTATGATACAATTGATTTTTGTTTA
AAAGCAATGGAGGATAATGT

Downstream 100 bases:

>100_bases
AGACGCACCGCGGGCTAGGATATAGTTTGGAGGAACAGAGTGAATAAGCTTGGAAAAAAGCTATTTCTTAGTATATCTTT
AACCGTTATTCTTATATTTA

Product: DNA-binding response regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 199; Mature: 199

Protein sequence:

>199_residues
MKVLIADDEQDMLRILKAYFEKEGFEVFLAKDGEEALQIFYDEKIDLAILDWMMPKHSGITVCQEIKKNSSVKVLMLTAK
SESEDELAALQSGADEYVKKTFHPGVLITRAKKLIQHDDVIQVQDLKIDFTKNKVYKNDKELDITKTELELIKCFLNHKG
MILTRKKLLDIVWGFDYFGEERTVDTHVRRLRKKLEKIL

Sequences:

>Translated_199_residues
MKVLIADDEQDMLRILKAYFEKEGFEVFLAKDGEEALQIFYDEKIDLAILDWMMPKHSGITVCQEIKKNSSVKVLMLTAK
SESEDELAALQSGADEYVKKTFHPGVLITRAKKLIQHDDVIQVQDLKIDFTKNKVYKNDKELDITKTELELIKCFLNHKG
MILTRKKLLDIVWGFDYFGEERTVDTHVRRLRKKLEKIL
>Mature_199_residues
MKVLIADDEQDMLRILKAYFEKEGFEVFLAKDGEEALQIFYDEKIDLAILDWMMPKHSGITVCQEIKKNSSVKVLMLTAK
SESEDELAALQSGADEYVKKTFHPGVLITRAKKLIQHDDVIQVQDLKIDFTKNKVYKNDKELDITKTELELIKCFLNHKG
MILTRKKLLDIVWGFDYFGEERTVDTHVRRLRKKLEKIL

Specific function: Member of the two-component regulatory system walK/walR that regulates genes involved in autolysis, biofilm formation and cell wall metabolism [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1786599, Length=205, Percent_Identity=35.1219512195122, Blast_Score=145, Evalue=1e-36,
Organism=Escherichia coli, GI1789809, Length=209, Percent_Identity=27.2727272727273, Blast_Score=120, Evalue=6e-29,
Organism=Escherichia coli, GI1786911, Length=203, Percent_Identity=32.0197044334975, Blast_Score=119, Evalue=1e-28,
Organism=Escherichia coli, GI1788394, Length=204, Percent_Identity=30.8823529411765, Blast_Score=111, Evalue=4e-26,
Organism=Escherichia coli, GI1790860, Length=204, Percent_Identity=32.843137254902, Blast_Score=104, Evalue=3e-24,
Organism=Escherichia coli, GI1790863, Length=209, Percent_Identity=28.7081339712919, Blast_Score=102, Evalue=2e-23,
Organism=Escherichia coli, GI1786784, Length=204, Percent_Identity=29.9019607843137, Blast_Score=101, Evalue=3e-23,
Organism=Escherichia coli, GI1787229, Length=207, Percent_Identity=26.0869565217391, Blast_Score=99, Evalue=2e-22,
Organism=Escherichia coli, GI87082012, Length=200, Percent_Identity=26.5, Blast_Score=97, Evalue=9e-22,
Organism=Escherichia coli, GI2367329, Length=207, Percent_Identity=29.951690821256, Blast_Score=95, Evalue=4e-21,
Organism=Escherichia coli, GI145693140, Length=210, Percent_Identity=26.6666666666667, Blast_Score=89, Evalue=2e-19,
Organism=Escherichia coli, GI1787375, Length=202, Percent_Identity=26.2376237623762, Blast_Score=89, Evalue=2e-19,
Organism=Escherichia coli, GI1788550, Length=102, Percent_Identity=36.2745098039216, Blast_Score=73, Evalue=1e-14,
Organism=Escherichia coli, GI1790552, Length=206, Percent_Identity=27.1844660194175, Blast_Score=72, Evalue=2e-14,
Organism=Escherichia coli, GI1789402, Length=201, Percent_Identity=24.8756218905473, Blast_Score=65, Evalue=4e-12,
Organism=Escherichia coli, GI1788191, Length=120, Percent_Identity=33.3333333333333, Blast_Score=63, Evalue=1e-11,
Organism=Escherichia coli, GI1790437, Length=101, Percent_Identity=34.6534653465347, Blast_Score=60, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 23223; Mature: 23223

Theoretical pI: Translated: 6.69; Mature: 6.69

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKVLIADDEQDMLRILKAYFEKEGFEVFLAKDGEEALQIFYDEKIDLAILDWMMPKHSGI
CEEEEECCHHHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHCCCCCEEHHHHHCCCCCCH
TVCQEIKKNSSVKVLMLTAKSESEDELAALQSGADEYVKKTFHPGVLITRAKKLIQHDDV
HHHHHHHCCCCEEEEEEEECCCCHHHHHHHHCCHHHHHHHHCCCCHHHHHHHHHHCCCCC
IQVQDLKIDFTKNKVYKNDKELDITKTELELIKCFLNHKGMILTRKKLLDIVWGFDYFGE
EEEEEEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHCCCCEEEEHHHHHHHHHCHHHCCC
ERTVDTHVRRLRKKLEKIL
CCCHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKVLIADDEQDMLRILKAYFEKEGFEVFLAKDGEEALQIFYDEKIDLAILDWMMPKHSGI
CEEEEECCHHHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHCCCCCEEHHHHHCCCCCCH
TVCQEIKKNSSVKVLMLTAKSESEDELAALQSGADEYVKKTFHPGVLITRAKKLIQHDDV
HHHHHHHCCCCEEEEEEEECCCCHHHHHHHHCCHHHHHHHHCCCCHHHHHHHHHHCCCCC
IQVQDLKIDFTKNKVYKNDKELDITKTELELIKCFLNHKGMILTRKKLLDIVWGFDYFGE
EEEEEEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHCCCCEEEEHHHHHHHHHCHHHCCC
ERTVDTHVRRLRKKLEKIL
CCCHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA