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The map label for this gene is mtnN [H]

Identifier: 227814324

GI number: 227814324

Start: 1581149

End: 1582528

Strand: Direct

Name: mtnN [H]

Synonym: BAMEG_1732

Alternate gene names: 227814324

Gene position: 1581149-1582528 (Clockwise)

Preceding gene: 227814323

Following gene: 227814325

Centisome position: 30.23

GC content: 33.62

Gene sequence:

>1380_bases
ATGAACAGAATCGGCATTATCGGAGCGATGCAAATTGAAATAGACTTACTTTTAGAAAAATTAATTATGCAAGAAGAACA
AATAATTGCAGGGATGCCTTTTTATGTTGGAGAATTCATGGGAACTGAAGTAATTGTTACAAGATGTGGTGTAGGGAAAG
TAAATGCAGCCGCATGTACGCAAACATTAATTCATAAATTTGATGTAGATGCTATCATCAATACAGGTGTTGCTGGAGGG
TTACACCCGGATGTAAAAGTTGGTGATATCGTTATTTCAACGAATGTTACCCATCATGATGTAAGTAAGACTCAAATGAA
AAACCTATTCCCGTTTCAAGAAGAATTTATCGCAAGTAAGGAATTAGTAGAGCTAGCGCGTAAAGCATGTAATAGTAGTT
CTTTACATATGGAAATTCATGAAGGAAGAATTGTAAGCGGTGAATGTTTTGTTGAAGATTCAAAACTAAAAGCGAAATTA
ATAGATGAATATGCACCGCATTGTACAGAAATGGAAGGTGCAGCAATTGGACATGTTGCCTACATAAATGAAGTACCGTT
TCTCGTAATACGATGTATTTCTGACAGTGCAGACGATGAAGCACAAATTTCTTATGATGACTTCGCGAAAACGGCCGCAA
ACTATTGTTCAGAAATTATCGTTGAGATGTTGAAAACTATATCGAGTAAAACTTATAGTTCAAAAGGAGAGAATGAAATG
TTACAAGCATTAATTTTTGATATGGACGGGACGTTATTTCAAACAGATAAAATTTTAGAGTTATCGTTAGATGATACATT
TGATCACTTAAGATCACTTCAATTATGGGATACGGTAACACCTATTGATAAGTACCGTGAAATTATGGGCGTGCCGTTAC
CGAAAGTTTGGGAAGCTTTATTACCGGATCATTCTCTTGAAATAAGAGAACAAACAGATGCATATTTTTTAGAAAGATTA
ATTGAAAACATTAAGAGCGGAAAAGGTGCTTTATATCCGAACGTAAAAGAAATTTTTACATATATAAAAGAAAATAATTG
CTCAATATATATTGCAAGTAATGGTTTAACTGAATATTTACGAGCAATTGTATCTTATTATGATTTAGACCAATGGGTTA
CTGAAACGTTTAGTATTGAACAAATAAACTCACTTAATAAAAGCGACTTAGTAAAAAGTATTTTGAACAAATATGATATA
AAAGAAGCAGCTGTAGTCGGGGATCGTTTATCTGATATAAACGCAGCTAAAGATAATGGCTTGATTGCGATTGGATGTAA
TTTTGATTTTGCACAAGAAGATGAACTTGCCCAAGCTGATATAGTAATAGATGATTTACTGGAGCTGAAGGGGATATTGT
CTACTGTGCAGAGATTATAA

Upstream 100 bases:

>100_bases
CCACCTTCACGTTTCGCGGATGAAATGAATTGGATAGCTAAAAATTACAGTGCATTACATAGTATATTGGCAGATTTATA
AGAAAAGGGAGATTACATTC

Downstream 100 bases:

>100_bases
AATGTGTGCAGTTTTTTGCCAATTCCTATATATCTTATTCCACGGAGGAAATATGCTTAAAGATAATTTTAATATTAGTA
ATATTCCCGCGGTTTTGTGG

Product: bifunctional 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase/phosphatase

Products: NA

Alternate protein names: MTA/SAH nucleosidase; MTAN; 5'-methylthioadenosine nucleosidase; MTA nucleosidase; S-adenosylhomocysteine nucleosidase; AdoHcy nucleosidase; SAH nucleosidase; SRH nucleosidase [H]

Number of amino acids: Translated: 459; Mature: 459

Protein sequence:

>459_residues
MNRIGIIGAMQIEIDLLLEKLIMQEEQIIAGMPFYVGEFMGTEVIVTRCGVGKVNAAACTQTLIHKFDVDAIINTGVAGG
LHPDVKVGDIVISTNVTHHDVSKTQMKNLFPFQEEFIASKELVELARKACNSSSLHMEIHEGRIVSGECFVEDSKLKAKL
IDEYAPHCTEMEGAAIGHVAYINEVPFLVIRCISDSADDEAQISYDDFAKTAANYCSEIIVEMLKTISSKTYSSKGENEM
LQALIFDMDGTLFQTDKILELSLDDTFDHLRSLQLWDTVTPIDKYREIMGVPLPKVWEALLPDHSLEIREQTDAYFLERL
IENIKSGKGALYPNVKEIFTYIKENNCSIYIASNGLTEYLRAIVSYYDLDQWVTETFSIEQINSLNKSDLVKSILNKYDI
KEAAVVGDRLSDINAAKDNGLIAIGCNFDFAQEDELAQADIVIDDLLELKGILSTVQRL

Sequences:

>Translated_459_residues
MNRIGIIGAMQIEIDLLLEKLIMQEEQIIAGMPFYVGEFMGTEVIVTRCGVGKVNAAACTQTLIHKFDVDAIINTGVAGG
LHPDVKVGDIVISTNVTHHDVSKTQMKNLFPFQEEFIASKELVELARKACNSSSLHMEIHEGRIVSGECFVEDSKLKAKL
IDEYAPHCTEMEGAAIGHVAYINEVPFLVIRCISDSADDEAQISYDDFAKTAANYCSEIIVEMLKTISSKTYSSKGENEM
LQALIFDMDGTLFQTDKILELSLDDTFDHLRSLQLWDTVTPIDKYREIMGVPLPKVWEALLPDHSLEIREQTDAYFLERL
IENIKSGKGALYPNVKEIFTYIKENNCSIYIASNGLTEYLRAIVSYYDLDQWVTETFSIEQINSLNKSDLVKSILNKYDI
KEAAVVGDRLSDINAAKDNGLIAIGCNFDFAQEDELAQADIVIDDLLELKGILSTVQRL
>Mature_459_residues
MNRIGIIGAMQIEIDLLLEKLIMQEEQIIAGMPFYVGEFMGTEVIVTRCGVGKVNAAACTQTLIHKFDVDAIINTGVAGG
LHPDVKVGDIVISTNVTHHDVSKTQMKNLFPFQEEFIASKELVELARKACNSSSLHMEIHEGRIVSGECFVEDSKLKAKL
IDEYAPHCTEMEGAAIGHVAYINEVPFLVIRCISDSADDEAQISYDDFAKTAANYCSEIIVEMLKTISSKTYSSKGENEM
LQALIFDMDGTLFQTDKILELSLDDTFDHLRSLQLWDTVTPIDKYREIMGVPLPKVWEALLPDHSLEIREQTDAYFLERL
IENIKSGKGALYPNVKEIFTYIKENNCSIYIASNGLTEYLRAIVSYYDLDQWVTETFSIEQINSLNKSDLVKSILNKYDI
KEAAVVGDRLSDINAAKDNGLIAIGCNFDFAQEDELAQADIVIDDLLELKGILSTVQRL

Specific function: Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively [H]

COG id: COG0546

COG function: function code R; Predicted phosphatases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PNP/UDP phosphorylase family. MtnN subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786354, Length=232, Percent_Identity=36.6379310344828, Blast_Score=120, Evalue=2e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010049
- InterPro:   IPR018017
- InterPro:   IPR000845 [H]

Pfam domain/function: PF01048 PNP_UDP_1 [H]

EC number: =3.2.2.9 [H]

Molecular weight: Translated: 51309; Mature: 51309

Theoretical pI: Translated: 4.33; Mature: 4.33

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNRIGIIGAMQIEIDLLLEKLIMQEEQIIAGMPFYVGEFMGTEVIVTRCGVGKVNAAACT
CCCEEEEEEEHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCEEEEEECCCCCCCHHHHH
QTLIHKFDVDAIINTGVAGGLHPDVKVGDIVISTNVTHHDVSKTQMKNLFPFQEEFIASK
HHHHHHHCHHHHHHCCCCCCCCCCCEECCEEEECCCCHHCCHHHHHHHCCCHHHHHHHHH
ELVELARKACNSSSLHMEIHEGRIVSGECFVEDSKLKAKLIDEYAPHCTEMEGAAIGHVA
HHHHHHHHHCCCCCEEEEEECCEEECCEEEEECCHHHHHHHHHHCCCCCCCCCCCCCHHH
YINEVPFLVIRCISDSADDEAQISYDDFAKTAANYCSEIIVEMLKTISSKTYSSKGENEM
HHHCCHHHHHHHHCCCCCCCCEECHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHH
LQALIFDMDGTLFQTDKILELSLDDTFDHLRSLQLWDTVTPIDKYREIMGVPLPKVWEAL
HHHHHHCCCCCEEECCCEEEEECHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCHHHHHHH
LPDHSLEIREQTDAYFLERLIENIKSGKGALYPNVKEIFTYIKENNCSIYIASNGLTEYL
CCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHCCCCEEEEECCCHHHHH
RAIVSYYDLDQWVTETFSIEQINSLNKSDLVKSILNKYDIKEAAVVGDRLSDINAAKDNG
HHHHHHHHHHHHHHHHCCHHHHHCCCHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCC
LIAIGCNFDFAQEDELAQADIVIDDLLELKGILSTVQRL
EEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MNRIGIIGAMQIEIDLLLEKLIMQEEQIIAGMPFYVGEFMGTEVIVTRCGVGKVNAAACT
CCCEEEEEEEHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCEEEEEECCCCCCCHHHHH
QTLIHKFDVDAIINTGVAGGLHPDVKVGDIVISTNVTHHDVSKTQMKNLFPFQEEFIASK
HHHHHHHCHHHHHHCCCCCCCCCCCEECCEEEECCCCHHCCHHHHHHHCCCHHHHHHHHH
ELVELARKACNSSSLHMEIHEGRIVSGECFVEDSKLKAKLIDEYAPHCTEMEGAAIGHVA
HHHHHHHHHCCCCCEEEEEECCEEECCEEEEECCHHHHHHHHHHCCCCCCCCCCCCCHHH
YINEVPFLVIRCISDSADDEAQISYDDFAKTAANYCSEIIVEMLKTISSKTYSSKGENEM
HHHCCHHHHHHHHCCCCCCCCEECHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHH
LQALIFDMDGTLFQTDKILELSLDDTFDHLRSLQLWDTVTPIDKYREIMGVPLPKVWEAL
HHHHHHCCCCCEEECCCEEEEECHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCHHHHHHH
LPDHSLEIREQTDAYFLERLIENIKSGKGALYPNVKEIFTYIKENNCSIYIASNGLTEYL
CCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHCCCCEEEEECCCHHHHH
RAIVSYYDLDQWVTETFSIEQINSLNKSDLVKSILNKYDIKEAAVVGDRLSDINAAKDNG
HHHHHHHHHHHHHHHHCCHHHHHCCCHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCC
LIAIGCNFDFAQEDELAQADIVIDDLLELKGILSTVQRL
EEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA