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The map label for this gene is aroA

Identifier: 227814241

GI number: 227814241

Start: 1514968

End: 1516257

Strand: Direct

Name: aroA

Synonym: BAMEG_1649

Alternate gene names: 227814241

Gene position: 1514968-1516257 (Clockwise)

Preceding gene: 227814240

Following gene: 227814242

Centisome position: 28.97

GC content: 39.07

Gene sequence:

>1290_bases
GTGAAGGAAAGAACAATACAACCTGTTAATAACGGATTAAATGGCAACATTACAATTCCAGGAGATAAATCGATTTCTCA
CCGCGCTGTCATGTTCGGCGCAATTGCAGAAGGAACAACAACAATTAAAGGATTCTTGCCTGGTGCAGACTGTTTAAGTA
CGATTTCTTGTTTTAAAGAAATGGGAGTAGACATTGTGCAAAACGGTGATGAAGTCACTGTAGTTGGTAAAGGATTAGAG
GGTTTACAAGAACCGAAAGCTGTATTAGATGTTGGTAATTCTGGTACAACTATACGTTTAATGTCAGGAATTTTGGCAAA
TACACCATTTCTCTCTTGCGTACAAGGCGATACATCTATTGCAAAAAGACCGATGAAACGTGTAACAAATCCATTAAAAC
AAATGGGTGCAAACATTGATGGACGCGAAGAAGGAACGTTTACACCGCTAACAATACGTGGTGGAGATTTAAAAGCAATT
GAATACACTTCCCCGGTAGCAAGCGCACAAGTAAAGTCAGCTATTTTACTTGCAGGACTTCGTGCAGAAGGTGTAACAGC
TGTTACAGAACCACATATTTCTCGTGATCATACGGAAAGAATGCTTGAAGCATTTGGCGTCAAAGTAACTCGCGAAGGGA
AAACAGTGAAACTAGCAGGTGGACAAAAATTAACAGCAACAGACGTTCAAGTGCCCGGTGACGTATCATCAGCTGCATTT
TTCTTAGTAGCGGGTGCAATTATTCCAAATAGTAAACTAGTATTAGAAAATGTAGGGATGAATCCAACTCGTACAGGTAT
TATTGATGTTTTAGAGAAAATGGGTGCTACGTTCACTGTAGAGCCAATTAACGAAGGAGCATCAGAACCAGCTGCAAATA
TTACAATCGAAACATCTTCATTAAAAGGAATCGAAATCGGTGGAGATATTATCCCTAGATTAATCGATGAAATTCCTGTA
ATTGCATTAGCGGCAACGCAAGCGGAAGGAATTACAGTTATTAAAGATGCACACGAATTAAAAGTAAAAGAAACAAACCG
TATTGATACAGTTGTTGCAGAGTTAACGAAACTAGGAGCTCGTATAGAAGCAACTGATGACAGAATGATCATTTACGGAA
AATCAGCTCTAAAAGGTAATACAGTTAATAGTTACGGTGATCACCGCATCGGAATGATGCTTGCGATTGCTGGATGTATC
GCAGAAGGAAAAACAATAATTGAAGACGCAGAAGCAGTAGGCGTATCATATCCTACGTTTTTCGAAGAACTTCAAAAGTT
GGCTAAATAA

Upstream 100 bases:

>100_bases
ATTAGCTTCCAGCGAGAAGAAGATCGTATGAAAGCAAAGCTAGCGCTTGGAGAAGAAAAATACCAAACTTATGAAACAAT
TTAAATGAGAAGGTGAAAAC

Downstream 100 bases:

>100_bases
AGTGAAACTTTAATCAGTGGGGGTCTTACTGCCCGTTAAAGCGGGATAAAGTAATGAGAAGCAGATACAAGATGTATCTG
CTTTTTTATATTGAATTCGT

Product: 3-phosphoshikimate 1-carboxyvinyltransferase

Products: NA

Alternate protein names: 5-enolpyruvylshikimate-3-phosphate synthase; EPSP synthase; EPSPS

Number of amino acids: Translated: 429; Mature: 429

Protein sequence:

>429_residues
MKERTIQPVNNGLNGNITIPGDKSISHRAVMFGAIAEGTTTIKGFLPGADCLSTISCFKEMGVDIVQNGDEVTVVGKGLE
GLQEPKAVLDVGNSGTTIRLMSGILANTPFLSCVQGDTSIAKRPMKRVTNPLKQMGANIDGREEGTFTPLTIRGGDLKAI
EYTSPVASAQVKSAILLAGLRAEGVTAVTEPHISRDHTERMLEAFGVKVTREGKTVKLAGGQKLTATDVQVPGDVSSAAF
FLVAGAIIPNSKLVLENVGMNPTRTGIIDVLEKMGATFTVEPINEGASEPAANITIETSSLKGIEIGGDIIPRLIDEIPV
IALAATQAEGITVIKDAHELKVKETNRIDTVVAELTKLGARIEATDDRMIIYGKSALKGNTVNSYGDHRIGMMLAIAGCI
AEGKTIIEDAEAVGVSYPTFFEELQKLAK

Sequences:

>Translated_429_residues
MKERTIQPVNNGLNGNITIPGDKSISHRAVMFGAIAEGTTTIKGFLPGADCLSTISCFKEMGVDIVQNGDEVTVVGKGLE
GLQEPKAVLDVGNSGTTIRLMSGILANTPFLSCVQGDTSIAKRPMKRVTNPLKQMGANIDGREEGTFTPLTIRGGDLKAI
EYTSPVASAQVKSAILLAGLRAEGVTAVTEPHISRDHTERMLEAFGVKVTREGKTVKLAGGQKLTATDVQVPGDVSSAAF
FLVAGAIIPNSKLVLENVGMNPTRTGIIDVLEKMGATFTVEPINEGASEPAANITIETSSLKGIEIGGDIIPRLIDEIPV
IALAATQAEGITVIKDAHELKVKETNRIDTVVAELTKLGARIEATDDRMIIYGKSALKGNTVNSYGDHRIGMMLAIAGCI
AEGKTIIEDAEAVGVSYPTFFEELQKLAK
>Mature_429_residues
MKERTIQPVNNGLNGNITIPGDKSISHRAVMFGAIAEGTTTIKGFLPGADCLSTISCFKEMGVDIVQNGDEVTVVGKGLE
GLQEPKAVLDVGNSGTTIRLMSGILANTPFLSCVQGDTSIAKRPMKRVTNPLKQMGANIDGREEGTFTPLTIRGGDLKAI
EYTSPVASAQVKSAILLAGLRAEGVTAVTEPHISRDHTERMLEAFGVKVTREGKTVKLAGGQKLTATDVQVPGDVSSAAF
FLVAGAIIPNSKLVLENVGMNPTRTGIIDVLEKMGATFTVEPINEGASEPAANITIETSSLKGIEIGGDIIPRLIDEIPV
IALAATQAEGITVIKDAHELKVKETNRIDTVVAELTKLGARIEATDDRMIIYGKSALKGNTVNSYGDHRIGMMLAIAGCI
AEGKTIIEDAEAVGVSYPTFFEELQKLAK

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; sixth step. [C]

COG id: COG0128

COG function: function code E; 5-enolpyruvylshikimate-3-phosphate synthase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the EPSP synthase family

Homologues:

Organism=Escherichia coli, GI1787137, Length=443, Percent_Identity=27.9909706546275, Blast_Score=142, Evalue=3e-35,
Organism=Saccharomyces cerevisiae, GI6320332, Length=456, Percent_Identity=25.8771929824561, Blast_Score=95, Evalue=2e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): AROA_BACAA (C3NZR4)

Other databases:

- EMBL:   CP001598
- RefSeq:   YP_002867201.1
- ProteinModelPortal:   C3NZR4
- SMR:   C3NZR4
- EnsemblBacteria:   EBBACT00000128251
- GeneID:   7853434
- GenomeReviews:   CP001598_GR
- KEGG:   bai:BAA_3008
- GeneTree:   EBGT00050000001036
- ProtClustDB:   PRK02427
- GO:   GO:0005737
- HAMAP:   MF_00210
- InterPro:   IPR001986
- InterPro:   IPR006264
- InterPro:   IPR023193
- InterPro:   IPR013792
- Gene3D:   G3DSA:3.65.10.10
- PIRSF:   PIRSF000505
- TIGRFAMs:   TIGR01356

Pfam domain/function: PF00275 EPSP_synthase; SSF55205 RNA3'_cycl/enolpyr_transf_A/B

EC number: =2.5.1.19

Molecular weight: Translated: 45265; Mature: 45265

Theoretical pI: Translated: 5.21; Mature: 5.21

Prosite motif: PS00104 EPSP_SYNTHASE_1; PS00885 EPSP_SYNTHASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKERTIQPVNNGLNGNITIPGDKSISHRAVMFGAIAEGTTTIKGFLPGADCLSTISCFKE
CCCCCCCHHCCCCCCCEECCCCCCCCCCEEEEEECCCCCEEEEECCCCHHHHHHHHHHHH
MGVDIVQNGDEVTVVGKGLEGLQEPKAVLDVGNSGTTIRLMSGILANTPFLSCVQGDTSI
CCCCEEECCCEEEEEECCCCCHHCCHHHEECCCCCCEEHHHHHHHHCCCCEEEECCCHHH
AKRPMKRVTNPLKQMGANIDGREEGTFTPLTIRGGDLKAIEYTSPVASAQVKSAILLAGL
HHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEEECCCEEEEEECCCHHHHHHHHHHHHEEC
RAEGVTAVTEPHISRDHTERMLEAFGVKVTREGKTVKLAGGQKLTATDVQVPGDVSSAAF
CCCCCEEECCCCCCHHHHHHHHHHHCCEEECCCCEEEEECCCEEEEECEECCCCCHHHHH
FLVAGAIIPNSKLVLENVGMNPTRTGIIDVLEKMGATFTVEPINEGASEPAANITIETSS
HHHHHHHCCCCEEEEEECCCCCCHHHHHHHHHHHCCEEEEEECCCCCCCCCCEEEEEECC
LKGIEIGGDIIPRLIDEIPVIALAATQAEGITVIKDAHELKVKETNRIDTVVAELTKLGA
CCCEEECHHHHHHHHHHCCEEEEEECCCCCEEEEECCHHEEECCCCHHHHHHHHHHHHCC
RIEATDDRMIIYGKSALKGNTVNSYGDHRIGMMLAIAGCIAEGKTIIEDAEAVGVSYPTF
EEEECCCEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHCCCCHHH
FEELQKLAK
HHHHHHHCC
>Mature Secondary Structure
MKERTIQPVNNGLNGNITIPGDKSISHRAVMFGAIAEGTTTIKGFLPGADCLSTISCFKE
CCCCCCCHHCCCCCCCEECCCCCCCCCCEEEEEECCCCCEEEEECCCCHHHHHHHHHHHH
MGVDIVQNGDEVTVVGKGLEGLQEPKAVLDVGNSGTTIRLMSGILANTPFLSCVQGDTSI
CCCCEEECCCEEEEEECCCCCHHCCHHHEECCCCCCEEHHHHHHHHCCCCEEEECCCHHH
AKRPMKRVTNPLKQMGANIDGREEGTFTPLTIRGGDLKAIEYTSPVASAQVKSAILLAGL
HHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEEECCCEEEEEECCCHHHHHHHHHHHHEEC
RAEGVTAVTEPHISRDHTERMLEAFGVKVTREGKTVKLAGGQKLTATDVQVPGDVSSAAF
CCCCCEEECCCCCCHHHHHHHHHHHCCEEECCCCEEEEECCCEEEEECEECCCCCHHHHH
FLVAGAIIPNSKLVLENVGMNPTRTGIIDVLEKMGATFTVEPINEGASEPAANITIETSS
HHHHHHHCCCCEEEEEECCCCCCHHHHHHHHHHHCCEEEEEECCCCCCCCCCEEEEEECC
LKGIEIGGDIIPRLIDEIPVIALAATQAEGITVIKDAHELKVKETNRIDTVVAELTKLGA
CCCEEECHHHHHHHHHHCCEEEEEECCCCCEEEEECCHHEEECCCCHHHHHHHHHHHHCC
RIEATDDRMIIYGKSALKGNTVNSYGDHRIGMMLAIAGCIAEGKTIIEDAEAVGVSYPTF
EEEECCCEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHCCCCHHH
FEELQKLAK
HHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA