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The map label for this gene is pcp

Identifier: 227814110

GI number: 227814110

Start: 1393494

End: 1394141

Strand: Direct

Name: pcp

Synonym: BAMEG_1517

Alternate gene names: 227814110

Gene position: 1393494-1394141 (Clockwise)

Preceding gene: 227814109

Following gene: 227814111

Centisome position: 26.64

GC content: 39.04

Gene sequence:

>648_bases
ATGAAAACAGTATTATTAACAGGATTTGATCCGTTCGGCGGAGAAAGTATCAATCCAGCTTGGGAAGTCGCAAAAAGTTT
GCATGAAAAAACAATCGGAGAATACAAGATTATTAGTAAACAAGTACCCACTGTATTTCATAAATCAATCAGCGTATTAA
AAGAGTATATAGAAGAACTAGCACCGGAATTTATTATATGCATTGGACAAGCTGGGGGTAGACCAGATATTACGATAGAG
CGTGTCGCAATTAATATTGATGATGCAAGAATTGCTGACAATGAAGGGAACCAACCGGTAGATGTACCGGTTGTAGAAGA
AGGACCAGCTGCTTATTGGTCTACACTTCCGATGAAAGCAATTGTAAAAAAACTTCAAGAAGAAGGTATACCGGCTTCCG
TTTCACAAACAGCAGGTACGTTCGTTTGTAATCATTTATTCTATGGTCTCATGCATGAATTAGAAAAACATGATACAAAA
ATGAAAGGCGGATTTATTCATATTCCGTTTTTACCAGAGCAAGCGAGTAATTATCCAGGGCAACCGAGTATGTCACTTTC
TACTATTCGTAAAGGGATAGAGTTGGCAGTTGAGGTAACGACGACCGTTGAGGTGGATATTGTAGAGGTTGGTGGCACGA
CGCATTAA

Upstream 100 bases:

>100_bases
GGACAGGAAAAAGGTGAGATTCCTTTTCGGTAGTTGGCATTTGACTTGGTTCGCCAACAATTTATAGGTTTTTATAAGAA
TTTTAAACCAGGAGAAAACT

Downstream 100 bases:

>100_bases
GTAGAATGAATTGTACAACACCTCCTGTAAACAACTGGTATAATAAGTATAGCAATATACATAGAGGTGATTTTTGTGCA
ACAATTTGAAGAAGTACGTA

Product: pyrrolidone-carboxylate peptidase

Products: NA

Alternate protein names: 5-oxoprolyl-peptidase; Pyroglutamyl-peptidase I; PGP-I; Pyrase

Number of amino acids: Translated: 215; Mature: 215

Protein sequence:

>215_residues
MKTVLLTGFDPFGGESINPAWEVAKSLHEKTIGEYKIISKQVPTVFHKSISVLKEYIEELAPEFIICIGQAGGRPDITIE
RVAINIDDARIADNEGNQPVDVPVVEEGPAAYWSTLPMKAIVKKLQEEGIPASVSQTAGTFVCNHLFYGLMHELEKHDTK
MKGGFIHIPFLPEQASNYPGQPSMSLSTIRKGIELAVEVTTTVEVDIVEVGGTTH

Sequences:

>Translated_215_residues
MKTVLLTGFDPFGGESINPAWEVAKSLHEKTIGEYKIISKQVPTVFHKSISVLKEYIEELAPEFIICIGQAGGRPDITIE
RVAINIDDARIADNEGNQPVDVPVVEEGPAAYWSTLPMKAIVKKLQEEGIPASVSQTAGTFVCNHLFYGLMHELEKHDTK
MKGGFIHIPFLPEQASNYPGQPSMSLSTIRKGIELAVEVTTTVEVDIVEVGGTTH
>Mature_215_residues
MKTVLLTGFDPFGGESINPAWEVAKSLHEKTIGEYKIISKQVPTVFHKSISVLKEYIEELAPEFIICIGQAGGRPDITIE
RVAINIDDARIADNEGNQPVDVPVVEEGPAAYWSTLPMKAIVKKLQEEGIPASVSQTAGTFVCNHLFYGLMHELEKHDTK
MKGGFIHIPFLPEQASNYPGQPSMSLSTIRKGIELAVEVTTTVEVDIVEVGGTTH

Specific function: Removes 5-oxoproline from various penultimate amino acid residues except L-proline

COG id: COG2039

COG function: function code O; Pyrrolidone-carboxylate peptidase (N-terminal pyroglutamyl peptidase)

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase C15 family

Homologues:

Organism=Homo sapiens, GI8923198, Length=178, Percent_Identity=24.7191011235955, Blast_Score=72, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): PCP_BACAA (C3P0R7)

Other databases:

- EMBL:   CP001598
- RefSeq:   YP_002867313.1
- ProteinModelPortal:   C3P0R7
- SMR:   C3P0R7
- EnsemblBacteria:   EBBACT00000129640
- GeneID:   7850231
- GenomeReviews:   CP001598_GR
- KEGG:   bai:BAA_3141
- GeneTree:   EBGT00050000001251
- ProtClustDB:   PRK13197
- GO:   GO:0005737
- GO:   GO:0006508
- HAMAP:   MF_00417
- InterPro:   IPR000816
- InterPro:   IPR016125
- Gene3D:   G3DSA:3.40.630.20
- PANTHER:   PTHR23402
- PIRSF:   PIRSF015592
- PRINTS:   PR00706
- TIGRFAMs:   TIGR00504

Pfam domain/function: PF01470 Peptidase_C15; SSF53182 Peptidase_C15-like

EC number: =3.4.19.3

Molecular weight: Translated: 23513; Mature: 23513

Theoretical pI: Translated: 4.84; Mature: 4.84

Prosite motif: PS01334 PYRASE_CYS; PS01333 PYRASE_GLU

Important sites: ACT_SITE 80-80 ACT_SITE 143-143 ACT_SITE 167-167

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTVLLTGFDPFGGESINPAWEVAKSLHEKTIGEYKIISKQVPTVFHKSISVLKEYIEEL
CCEEEEECCCCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
APEFIICIGQAGGRPDITIERVAINIDDARIADNEGNQPVDVPVVEEGPAAYWSTLPMKA
CCCEEEEEECCCCCCCEEEEEEEEECCCCEECCCCCCCCCCCEEECCCCCHHHHHCCHHH
IVKKLQEEGIPASVSQTAGTFVCNHLFYGLMHELEKHDTKMKGGFIHIPFLPEQASNYPG
HHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCHHHCCCCC
QPSMSLSTIRKGIELAVEVTTTVEVDIVEVGGTTH
CCCCCHHHHHHCCEEEEEEEEEEEEEEEECCCCCC
>Mature Secondary Structure
MKTVLLTGFDPFGGESINPAWEVAKSLHEKTIGEYKIISKQVPTVFHKSISVLKEYIEEL
CCEEEEECCCCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
APEFIICIGQAGGRPDITIERVAINIDDARIADNEGNQPVDVPVVEEGPAAYWSTLPMKA
CCCEEEEEECCCCCCCEEEEEEEEECCCCEECCCCCCCCCCCEEECCCCCHHHHHCCHHH
IVKKLQEEGIPASVSQTAGTFVCNHLFYGLMHELEKHDTKMKGGFIHIPFLPEQASNYPG
HHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCHHHCCCCC
QPSMSLSTIRKGIELAVEVTTTVEVDIVEVGGTTH
CCCCCHHHHHHCCEEEEEEEEEEEEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA