Definition Bacillus anthracis str. CDC 684, complete genome.
Accession NC_012581
Length 5,230,115

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The map label for this gene is yfnA [H]

Identifier: 227814064

GI number: 227814064

Start: 1350999

End: 1352414

Strand: Direct

Name: yfnA [H]

Synonym: BAMEG_1471

Alternate gene names: 227814064

Gene position: 1350999-1352414 (Clockwise)

Preceding gene: 227814063

Following gene: 227814065

Centisome position: 25.83

GC content: 36.23

Gene sequence:

>1416_bases
ATGAGTAAGTTATTAAAAAAGAAATCCGTTACACAATTGTTGGAGCATAATCAAAGTAAGGCCTTAACGAAAACATTAGG
AGCATTTGATTTAATTATGTTAGGGGTAGGCTCGATAATTGGAACGGGGGTTCTTGTGTTAACTGGATTAGTAGCAGCAA
GAGATGCTGGTCCAGCAGTTATTTTTTCATTTGTACTTGCAGCAATTATATGCGGATTTATAGCATTATGTTACGCAGAA
ATTGCTTCCACACTCCCGGCGTCTGGTAGTGTATATACGTACTCATATGCAACAATTGGTGAGTTTGTTGCTCATCTAGT
AGGTTGGTCTTTACTGTTAATATATATTGTGGCAACAGCGGCTGTCGCTGCTGGATGGACAGGCTATTTCCACAATTTAA
TAAAAGGGTTTGGATTAGAGATACCTAAAGCTCTAGTAACGATCCCTTCACATGGTGGTATTGTGAATCTACCAGCAGTA
ATCATTACATTGATATTAGCATGGATGTTATCCCGTGGTACAAGGGAAAGTAAACGAATCAATAATATAATGGTATTGAT
TAAAATTGGTATGATTTTGTTGTTTATTACAGTTGGTATATTCTATGTAAAACCAATGAACTGGATACCAATTGCACCAT
ACGGTTTAAGTGGGGTTTTTACGGGTGGAGCAGCTATTTTATTCGCTTTCACAGGTTTTGATATATTAGCAACTTCAGCA
GAAGAAGTAAAAGATCCGAAGCGGAATCTTCCCATCGGTATTATTGCATCATTAATCATATGTACAATTATTTATGTTAT
GGTATGCCTTGTTATGACAGGAATGGTTTCCTATAAAGAATTAAATGTCCCTGAGGCAATGGCTTATGTAATGGAAGTGG
TAGGACAAGGAAAAGTCGCTGGTGCAATTGCTGTAGGAGCTGTAATTGGCCTTATGGCTGTTATTTTTTCCAATATGTAT
GCGGCAACACGAGTATTCTTTGCAATGAGTCGTGATGGATTGTTACCGAAATCATTTGCGAAAGTTAATAAGAAAACTGG
AGCACCCACTTTTATAACTGGATTGGCAGGAATAGGGAGCTCTATAATAGCTGGGTTTATTGATTTAAAAGAATTGGTTA
ATTTAGTTAATATCGGTAGTTTGGTGACGTTTGCGTTAGTTTGTCTATCAGTTATTATTCTCCGTAAATCACACCCAAAT
TTAAAACGTGGATTTATGGTACCTTTTGTACCTGTATTACCATGCGTTGCAATTGTATGCTGTGTGTTTTTAATGCTAAA
TTTACCGTTAAGGACATGGGTGTACTTTAGCATTTGGATTACTATTGGGGTAGTAATATATTTCCTTTATTCGATAAAAC
ACAGTAATTTAAATGAGGAAACGATCTCGAAATTACATGATAAAATTGCGAGATAA

Upstream 100 bases:

>100_bases
AACGTAAAAGAAATATTATAAGACTATCTAATAACTAAGTAAATTTATATACAACAATAATGAGAAGAGCAAACCTTATT
TTAAAGGGAATACAGAGAAT

Downstream 100 bases:

>100_bases
TAACGATAGAAAATTTTATTAATAATCATATTGATAGTTGAGTAACATAGAAACAGTTTTTTGACATTTAGCAAGAAATA
AAATGAAAAATCCTAGGACA

Product: amino acid permease family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 471; Mature: 470

Protein sequence:

>471_residues
MSKLLKKKSVTQLLEHNQSKALTKTLGAFDLIMLGVGSIIGTGVLVLTGLVAARDAGPAVIFSFVLAAIICGFIALCYAE
IASTLPASGSVYTYSYATIGEFVAHLVGWSLLLIYIVATAAVAAGWTGYFHNLIKGFGLEIPKALVTIPSHGGIVNLPAV
IITLILAWMLSRGTRESKRINNIMVLIKIGMILLFITVGIFYVKPMNWIPIAPYGLSGVFTGGAAILFAFTGFDILATSA
EEVKDPKRNLPIGIIASLIICTIIYVMVCLVMTGMVSYKELNVPEAMAYVMEVVGQGKVAGAIAVGAVIGLMAVIFSNMY
AATRVFFAMSRDGLLPKSFAKVNKKTGAPTFITGLAGIGSSIIAGFIDLKELVNLVNIGSLVTFALVCLSVIILRKSHPN
LKRGFMVPFVPVLPCVAIVCCVFLMLNLPLRTWVYFSIWITIGVVIYFLYSIKHSNLNEETISKLHDKIAR

Sequences:

>Translated_471_residues
MSKLLKKKSVTQLLEHNQSKALTKTLGAFDLIMLGVGSIIGTGVLVLTGLVAARDAGPAVIFSFVLAAIICGFIALCYAE
IASTLPASGSVYTYSYATIGEFVAHLVGWSLLLIYIVATAAVAAGWTGYFHNLIKGFGLEIPKALVTIPSHGGIVNLPAV
IITLILAWMLSRGTRESKRINNIMVLIKIGMILLFITVGIFYVKPMNWIPIAPYGLSGVFTGGAAILFAFTGFDILATSA
EEVKDPKRNLPIGIIASLIICTIIYVMVCLVMTGMVSYKELNVPEAMAYVMEVVGQGKVAGAIAVGAVIGLMAVIFSNMY
AATRVFFAMSRDGLLPKSFAKVNKKTGAPTFITGLAGIGSSIIAGFIDLKELVNLVNIGSLVTFALVCLSVIILRKSHPN
LKRGFMVPFVPVLPCVAIVCCVFLMLNLPLRTWVYFSIWITIGVVIYFLYSIKHSNLNEETISKLHDKIAR
>Mature_470_residues
SKLLKKKSVTQLLEHNQSKALTKTLGAFDLIMLGVGSIIGTGVLVLTGLVAARDAGPAVIFSFVLAAIICGFIALCYAEI
ASTLPASGSVYTYSYATIGEFVAHLVGWSLLLIYIVATAAVAAGWTGYFHNLIKGFGLEIPKALVTIPSHGGIVNLPAVI
ITLILAWMLSRGTRESKRINNIMVLIKIGMILLFITVGIFYVKPMNWIPIAPYGLSGVFTGGAAILFAFTGFDILATSAE
EVKDPKRNLPIGIIASLIICTIIYVMVCLVMTGMVSYKELNVPEAMAYVMEVVGQGKVAGAIAVGAVIGLMAVIFSNMYA
ATRVFFAMSRDGLLPKSFAKVNKKTGAPTFITGLAGIGSSIIAGFIDLKELVNLVNIGSLVTFALVCLSVIILRKSHPNL
KRGFMVPFVPVLPCVAIVCCVFLMLNLPLRTWVYFSIWITIGVVIYFLYSIKHSNLNEETISKLHDKIAR

Specific function: Probable Amino-Acid Or Metabolite Transport Protein. [C]

COG id: COG0531

COG function: function code E; Amino acid transporters

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the amino acid-polyamine-organocation (APC) superfamily [H]

Homologues:

Organism=Homo sapiens, GI4507047, Length=433, Percent_Identity=36.9515011547344, Blast_Score=244, Evalue=1e-64,
Organism=Homo sapiens, GI258645169, Length=425, Percent_Identity=35.0588235294118, Blast_Score=238, Evalue=8e-63,
Organism=Homo sapiens, GI258614005, Length=425, Percent_Identity=34.5882352941176, Blast_Score=237, Evalue=2e-62,
Organism=Homo sapiens, GI258614003, Length=425, Percent_Identity=34.5882352941176, Blast_Score=236, Evalue=3e-62,
Organism=Homo sapiens, GI181337167, Length=428, Percent_Identity=33.1775700934579, Blast_Score=223, Evalue=3e-58,
Organism=Homo sapiens, GI114326544, Length=427, Percent_Identity=31.1475409836066, Blast_Score=211, Evalue=1e-54,
Organism=Homo sapiens, GI114326550, Length=427, Percent_Identity=31.1475409836066, Blast_Score=211, Evalue=1e-54,
Organism=Homo sapiens, GI110347453, Length=404, Percent_Identity=34.9009900990099, Blast_Score=210, Evalue=2e-54,
Organism=Homo sapiens, GI7657683, Length=426, Percent_Identity=26.5258215962441, Blast_Score=99, Evalue=1e-20,
Organism=Homo sapiens, GI33286428, Length=452, Percent_Identity=26.3274336283186, Blast_Score=96, Evalue=6e-20,
Organism=Homo sapiens, GI115648063, Length=433, Percent_Identity=23.5565819861432, Blast_Score=91, Evalue=2e-18,
Organism=Homo sapiens, GI115648022, Length=433, Percent_Identity=23.5565819861432, Blast_Score=91, Evalue=2e-18,
Organism=Homo sapiens, GI186910308, Length=421, Percent_Identity=23.5154394299287, Blast_Score=91, Evalue=2e-18,
Organism=Homo sapiens, GI186910306, Length=421, Percent_Identity=23.5154394299287, Blast_Score=91, Evalue=2e-18,
Organism=Homo sapiens, GI186910304, Length=421, Percent_Identity=23.5154394299287, Blast_Score=91, Evalue=2e-18,
Organism=Homo sapiens, GI187423910, Length=477, Percent_Identity=24.5283018867925, Blast_Score=90, Evalue=5e-18,
Organism=Homo sapiens, GI7657591, Length=477, Percent_Identity=24.5283018867925, Blast_Score=90, Evalue=5e-18,
Organism=Homo sapiens, GI71979932, Length=227, Percent_Identity=27.3127753303965, Blast_Score=76, Evalue=7e-14,
Organism=Homo sapiens, GI9790235, Length=302, Percent_Identity=24.1721854304636, Blast_Score=75, Evalue=2e-13,
Organism=Homo sapiens, GI33286430, Length=234, Percent_Identity=23.5042735042735, Blast_Score=66, Evalue=9e-11,
Organism=Escherichia coli, GI87082023, Length=458, Percent_Identity=29.4759825327511, Blast_Score=107, Evalue=2e-24,
Organism=Escherichia coli, GI87081708, Length=485, Percent_Identity=22.0618556701031, Blast_Score=105, Evalue=7e-24,
Organism=Escherichia coli, GI1788480, Length=465, Percent_Identity=23.4408602150538, Blast_Score=89, Evalue=9e-19,
Organism=Escherichia coli, GI1790653, Length=447, Percent_Identity=24.1610738255034, Blast_Score=86, Evalue=7e-18,
Organism=Escherichia coli, GI87081869, Length=391, Percent_Identity=24.8081841432225, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI2367353, Length=464, Percent_Identity=23.0603448275862, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1786694, Length=328, Percent_Identity=25.9146341463415, Blast_Score=76, Evalue=5e-15,
Organism=Escherichia coli, GI87082250, Length=351, Percent_Identity=25.9259259259259, Blast_Score=70, Evalue=4e-13,
Organism=Escherichia coli, GI1789017, Length=362, Percent_Identity=23.2044198895028, Blast_Score=69, Evalue=5e-13,
Organism=Escherichia coli, GI1786908, Length=396, Percent_Identity=24.2424242424242, Blast_Score=66, Evalue=5e-12,
Organism=Escherichia coli, GI1786602, Length=397, Percent_Identity=22.4181360201511, Blast_Score=62, Evalue=8e-11,
Organism=Caenorhabditis elegans, GI17532491, Length=414, Percent_Identity=34.2995169082126, Blast_Score=237, Evalue=9e-63,
Organism=Caenorhabditis elegans, GI17531343, Length=411, Percent_Identity=33.0900243309002, Blast_Score=202, Evalue=2e-52,
Organism=Caenorhabditis elegans, GI17533459, Length=412, Percent_Identity=31.7961165048544, Blast_Score=196, Evalue=2e-50,
Organism=Caenorhabditis elegans, GI71982612, Length=374, Percent_Identity=24.331550802139, Blast_Score=100, Evalue=3e-21,
Organism=Caenorhabditis elegans, GI71982608, Length=374, Percent_Identity=24.331550802139, Blast_Score=99, Evalue=4e-21,
Organism=Caenorhabditis elegans, GI17568033, Length=431, Percent_Identity=21.8097447795824, Blast_Score=94, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI32566699, Length=339, Percent_Identity=27.1386430678466, Blast_Score=83, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI193208714, Length=426, Percent_Identity=24.4131455399061, Blast_Score=83, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI17540018, Length=203, Percent_Identity=26.6009852216749, Blast_Score=83, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI17537453, Length=372, Percent_Identity=23.6559139784946, Blast_Score=83, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI32566695, Length=426, Percent_Identity=24.4131455399061, Blast_Score=83, Evalue=4e-16,
Organism=Caenorhabditis elegans, GI71993915, Length=410, Percent_Identity=22.6829268292683, Blast_Score=72, Evalue=5e-13,
Organism=Caenorhabditis elegans, GI71995388, Length=423, Percent_Identity=21.9858156028369, Blast_Score=67, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI71995382, Length=423, Percent_Identity=21.9858156028369, Blast_Score=67, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI71982623, Length=244, Percent_Identity=25.8196721311475, Blast_Score=65, Evalue=6e-11,
Organism=Saccharomyces cerevisiae, GI6319543, Length=364, Percent_Identity=23.9010989010989, Blast_Score=66, Evalue=1e-11,
Organism=Drosophila melanogaster, GI221512776, Length=422, Percent_Identity=36.0189573459716, Blast_Score=261, Evalue=7e-70,
Organism=Drosophila melanogaster, GI24666159, Length=422, Percent_Identity=36.0189573459716, Blast_Score=261, Evalue=7e-70,
Organism=Drosophila melanogaster, GI24668806, Length=422, Percent_Identity=35.5450236966825, Blast_Score=251, Evalue=1e-66,
Organism=Drosophila melanogaster, GI21356285, Length=422, Percent_Identity=35.5450236966825, Blast_Score=251, Evalue=1e-66,
Organism=Drosophila melanogaster, GI24668802, Length=422, Percent_Identity=35.5450236966825, Blast_Score=251, Evalue=1e-66,
Organism=Drosophila melanogaster, GI24667468, Length=405, Percent_Identity=35.0617283950617, Blast_Score=244, Evalue=8e-65,
Organism=Drosophila melanogaster, GI161077963, Length=403, Percent_Identity=35.9801488833747, Blast_Score=232, Evalue=3e-61,
Organism=Drosophila melanogaster, GI281366235, Length=414, Percent_Identity=32.8502415458937, Blast_Score=203, Evalue=2e-52,
Organism=Drosophila melanogaster, GI116007820, Length=414, Percent_Identity=32.8502415458937, Blast_Score=203, Evalue=2e-52,
Organism=Drosophila melanogaster, GI116007818, Length=416, Percent_Identity=32.9326923076923, Blast_Score=199, Evalue=2e-51,
Organism=Drosophila melanogaster, GI85725152, Length=416, Percent_Identity=32.9326923076923, Blast_Score=199, Evalue=2e-51,
Organism=Drosophila melanogaster, GI21357367, Length=439, Percent_Identity=24.6013667425968, Blast_Score=103, Evalue=2e-22,
Organism=Drosophila melanogaster, GI24651635, Length=398, Percent_Identity=24.8743718592965, Blast_Score=96, Evalue=7e-20,
Organism=Drosophila melanogaster, GI24651633, Length=398, Percent_Identity=24.8743718592965, Blast_Score=96, Evalue=7e-20,
Organism=Drosophila melanogaster, GI221331183, Length=419, Percent_Identity=25.7756563245823, Blast_Score=92, Evalue=5e-19,
Organism=Drosophila melanogaster, GI17647653, Length=419, Percent_Identity=25.7756563245823, Blast_Score=92, Evalue=5e-19,
Organism=Drosophila melanogaster, GI24664379, Length=419, Percent_Identity=25.7756563245823, Blast_Score=92, Evalue=5e-19,
Organism=Drosophila melanogaster, GI45550968, Length=428, Percent_Identity=25.7009345794392, Blast_Score=87, Evalue=2e-17,
Organism=Drosophila melanogaster, GI19921172, Length=428, Percent_Identity=25.7009345794392, Blast_Score=87, Evalue=2e-17,
Organism=Drosophila melanogaster, GI24641993, Length=423, Percent_Identity=24.5862884160757, Blast_Score=83, Evalue=4e-16,
Organism=Drosophila melanogaster, GI24641995, Length=423, Percent_Identity=24.5862884160757, Blast_Score=83, Evalue=4e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004841
- InterPro:   IPR002293
- InterPro:   IPR015606 [H]

Pfam domain/function: PF00324 AA_permease [H]

EC number: NA

Molecular weight: Translated: 50582; Mature: 50451

Theoretical pI: Translated: 9.81; Mature: 9.81

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure: 

>Translated Secondary Structure
MSKLLKKKSVTQLLEHNQSKALTKTLGAFDLIMLGVGSIIGTGVLVLTGLVAARDAGPAV
CCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHH
IFSFVLAAIICGFIALCYAEIASTLPASGSVYTYSYATIGEFVAHLVGWSLLLIYIVATA
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHH
AVAAGWTGYFHNLIKGFGLEIPKALVTIPSHGGIVNLPAVIITLILAWMLSRGTRESKRI
HHHHHHHHHHHHHHHHHCCCCCHHHEECCCCCCEEEHHHHHHHHHHHHHHHCCCCHHHHH
NNIMVLIKIGMILLFITVGIFYVKPMNWIPIAPYGLSGVFTGGAAILFAFTGFDILATSA
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHCCHHHHHHHHHHHHHHHCCH
EEVKDPKRNLPIGIIASLIICTIIYVMVCLVMTGMVSYKELNVPEAMAYVMEVVGQGKVA
HHHCCCHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCHH
GAIAVGAVIGLMAVIFSNMYAATRVFFAMSRDGLLPKSFAKVNKKTGAPTFITGLAGIGS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCHHHHHHHHHHH
SIIAGFIDLKELVNLVNIGSLVTFALVCLSVIILRKSHPNLKRGFMVPFVPVLPCVAIVC
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHCCCCCCHHHHHHHHHHHH
CVFLMLNLPLRTWVYFSIWITIGVVIYFLYSIKHSNLNEETISKLHDKIAR
HHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCC
>Mature Secondary Structure 
SKLLKKKSVTQLLEHNQSKALTKTLGAFDLIMLGVGSIIGTGVLVLTGLVAARDAGPAV
CHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHH
IFSFVLAAIICGFIALCYAEIASTLPASGSVYTYSYATIGEFVAHLVGWSLLLIYIVATA
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHH
AVAAGWTGYFHNLIKGFGLEIPKALVTIPSHGGIVNLPAVIITLILAWMLSRGTRESKRI
HHHHHHHHHHHHHHHHHCCCCCHHHEECCCCCCEEEHHHHHHHHHHHHHHHCCCCHHHHH
NNIMVLIKIGMILLFITVGIFYVKPMNWIPIAPYGLSGVFTGGAAILFAFTGFDILATSA
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHCCHHHHHHHHHHHHHHHCCH
EEVKDPKRNLPIGIIASLIICTIIYVMVCLVMTGMVSYKELNVPEAMAYVMEVVGQGKVA
HHHCCCHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCHH
GAIAVGAVIGLMAVIFSNMYAATRVFFAMSRDGLLPKSFAKVNKKTGAPTFITGLAGIGS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCHHHHHHHHHHH
SIIAGFIDLKELVNLVNIGSLVTFALVCLSVIILRKSHPNLKRGFMVPFVPVLPCVAIVC
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHCCCCCCHHHHHHHHHHHH
CVFLMLNLPLRTWVYFSIWITIGVVIYFLYSIKHSNLNEETISKLHDKIAR
HHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9141694; 9384377 [H]