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The map label for this gene is glsA2

Identifier: 227814048

GI number: 227814048

Start: 1337083

End: 1338063

Strand: Direct

Name: glsA2

Synonym: BAMEG_1455

Alternate gene names: 227814048

Gene position: 1337083-1338063 (Clockwise)

Preceding gene: 227814047

Following gene: 227814049

Centisome position: 25.57

GC content: 36.7

Gene sequence:

>981_bases
ATGATAAAGGATTCTAGCGTTCAAGTTGAGGGTCAAGAAAAAGTTTGCTTAGATCAATGGGTAGCTCATTATCGAACGTA
TGCAGCTAAGGGACGAAGCGCCAGTTATATTCCAGCTCTGGGGGAAATAAATGTATCGCAGTTAGGTATTTGTATAGTAA
AGCCAGATGGAACAATGATAAAGTCAGGAGATTGGGAGATACCTTTCACATTACAAAGTATATCAAAAGTAATCGGTTTT
ATAGCCGCTTGTTTAAGTCGCGGTATTTCTTATGTATTAGAACGAGTTGACGTAGAGCCAACTGGAGATGCCTTTAATTC
GATTATTCGTTTGGAGATACATAAACCAGGAAAACCTTTTAATCCTATGATTAATGCTGGAGCAATTACGATAGCTTCAC
TTTTGCCAGGGACATCGGTGCAAGAAAAATTAGAATCTATATACGTATTAATTGAAAAAATGATAGAGAAACGTCCCGCT
ATTAATGAAATAGTATTTCAATCAGAATGGGAAACGGCTCATCGTAATAGAGCATTAGCATACTATTTAAAGGAAAATGG
TTTTCTAGAATCAGATGTGGAGGAGACACTAGAGGTTTACCTAAAACAATGTTCGATTGAAATAAATACAGAAGATATTG
CCTTAATAGGGCTTATACTAGCACATGATGGATATCATCCTATTCGCAAAGAACAAGTGCTCCCTAAAGAAGTAGCTAGG
TTAACAAAAGCTTTAATGCTTACTTGTGGAATGTACAATGCTTCTGGAAAATTTGCTGCTTTCATTGGATTACCAGCTAA
GAGTGGGGTATCCGGCGGAATTATGACACTTGTTCCCTCAAAATCTAGGAAGGATTTATCGTTCCAAGATGGATGTGGTA
TTGGTATTTACGGACCAGCCATTGATGAGTATGGGAATAGTTTACCAGGAATTATGTTGTTAGAACATATTGCAAAAGAA
TGGGATTTAAGTATATTTTAA

Upstream 100 bases:

>100_bases
ATGTCTGAATATTTTTCTTGGTTCTAGTGCAAATATTATTGATTATAGTAAAGAAAAAATCATTCTATATAAAGTTAATA
GTACGGGGGAATATGATTAA

Downstream 100 bases:

>100_bases
AAAGGAGCACAGATATTTTGGTGTTAGAGCGAGTCCAAAAGTGTTCAGACCTTATATTGTGTCTGAACATTTTTGAGTTA
TAAAGTATCTTTCTAAAGTA

Product: glutaminase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 326; Mature: 326

Protein sequence:

>326_residues
MIKDSSVQVEGQEKVCLDQWVAHYRTYAAKGRSASYIPALGEINVSQLGICIVKPDGTMIKSGDWEIPFTLQSISKVIGF
IAACLSRGISYVLERVDVEPTGDAFNSIIRLEIHKPGKPFNPMINAGAITIASLLPGTSVQEKLESIYVLIEKMIEKRPA
INEIVFQSEWETAHRNRALAYYLKENGFLESDVEETLEVYLKQCSIEINTEDIALIGLILAHDGYHPIRKEQVLPKEVAR
LTKALMLTCGMYNASGKFAAFIGLPAKSGVSGGIMTLVPSKSRKDLSFQDGCGIGIYGPAIDEYGNSLPGIMLLEHIAKE
WDLSIF

Sequences:

>Translated_326_residues
MIKDSSVQVEGQEKVCLDQWVAHYRTYAAKGRSASYIPALGEINVSQLGICIVKPDGTMIKSGDWEIPFTLQSISKVIGF
IAACLSRGISYVLERVDVEPTGDAFNSIIRLEIHKPGKPFNPMINAGAITIASLLPGTSVQEKLESIYVLIEKMIEKRPA
INEIVFQSEWETAHRNRALAYYLKENGFLESDVEETLEVYLKQCSIEINTEDIALIGLILAHDGYHPIRKEQVLPKEVAR
LTKALMLTCGMYNASGKFAAFIGLPAKSGVSGGIMTLVPSKSRKDLSFQDGCGIGIYGPAIDEYGNSLPGIMLLEHIAKE
WDLSIF
>Mature_326_residues
MIKDSSVQVEGQEKVCLDQWVAHYRTYAAKGRSASYIPALGEINVSQLGICIVKPDGTMIKSGDWEIPFTLQSISKVIGF
IAACLSRGISYVLERVDVEPTGDAFNSIIRLEIHKPGKPFNPMINAGAITIASLLPGTSVQEKLESIYVLIEKMIEKRPA
INEIVFQSEWETAHRNRALAYYLKENGFLESDVEETLEVYLKQCSIEINTEDIALIGLILAHDGYHPIRKEQVLPKEVAR
LTKALMLTCGMYNASGKFAAFIGLPAKSGVSGGIMTLVPSKSRKDLSFQDGCGIGIYGPAIDEYGNSLPGIMLLEHIAKE
WDLSIF

Specific function: Unknown

COG id: COG2066

COG function: function code E; Glutaminase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glutaminase family

Homologues:

Organism=Homo sapiens, GI156104878, Length=311, Percent_Identity=36.9774919614148, Blast_Score=185, Evalue=5e-47,
Organism=Homo sapiens, GI20336214, Length=297, Percent_Identity=35.016835016835, Blast_Score=170, Evalue=2e-42,
Organism=Escherichia coli, GI1786693, Length=296, Percent_Identity=35.8108108108108, Blast_Score=187, Evalue=7e-49,
Organism=Escherichia coli, GI1787804, Length=314, Percent_Identity=33.7579617834395, Blast_Score=183, Evalue=1e-47,
Organism=Caenorhabditis elegans, GI17507019, Length=301, Percent_Identity=33.5548172757475, Blast_Score=174, Evalue=7e-44,
Organism=Caenorhabditis elegans, GI17532727, Length=299, Percent_Identity=32.7759197324415, Blast_Score=167, Evalue=5e-42,
Organism=Caenorhabditis elegans, GI193204073, Length=308, Percent_Identity=32.4675324675325, Blast_Score=159, Evalue=1e-39,
Organism=Caenorhabditis elegans, GI193204075, Length=310, Percent_Identity=32.9032258064516, Blast_Score=157, Evalue=9e-39,
Organism=Drosophila melanogaster, GI281363239, Length=304, Percent_Identity=34.5394736842105, Blast_Score=174, Evalue=6e-44,
Organism=Drosophila melanogaster, GI281363241, Length=301, Percent_Identity=34.8837209302326, Blast_Score=174, Evalue=6e-44,
Organism=Drosophila melanogaster, GI24653156, Length=304, Percent_Identity=34.5394736842105, Blast_Score=174, Evalue=7e-44,
Organism=Drosophila melanogaster, GI116008307, Length=304, Percent_Identity=34.5394736842105, Blast_Score=174, Evalue=7e-44,
Organism=Drosophila melanogaster, GI24653162, Length=301, Percent_Identity=34.8837209302326, Blast_Score=174, Evalue=7e-44,
Organism=Drosophila melanogaster, GI24653158, Length=304, Percent_Identity=34.5394736842105, Blast_Score=174, Evalue=7e-44,
Organism=Drosophila melanogaster, GI24653164, Length=304, Percent_Identity=34.5394736842105, Blast_Score=174, Evalue=8e-44,
Organism=Drosophila melanogaster, GI24653166, Length=304, Percent_Identity=34.5394736842105, Blast_Score=174, Evalue=9e-44,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): GLSA2_BACAN (Q81NN0)

Other databases:

- EMBL:   AE016879
- EMBL:   AE017334
- EMBL:   AE017225
- RefSeq:   NP_845472.1
- RefSeq:   YP_019795.1
- RefSeq:   YP_029190.1
- ProteinModelPortal:   Q81NN0
- SMR:   Q81NN0
- IntAct:   Q81NN0
- EnsemblBacteria:   EBBACT00000008453
- EnsemblBacteria:   EBBACT00000018069
- EnsemblBacteria:   EBBACT00000023608
- GeneID:   1086611
- GeneID:   2815154
- GeneID:   2852277
- GenomeReviews:   AE016879_GR
- GenomeReviews:   AE017225_GR
- GenomeReviews:   AE017334_GR
- KEGG:   ban:BA_3155
- KEGG:   bar:GBAA_3155
- KEGG:   bat:BAS2932
- TIGR:   BA_3155
- TIGR:   GBAA_3155
- GeneTree:   EBGT00050000001778
- HOGENOM:   HBG512335
- OMA:   NALMLTC
- ProtClustDB:   PRK12357
- BioCyc:   BANT260799:BAS2932-MONOMER
- BioCyc:   BANT261594:GBAA3155-MONOMER
- BRENDA:   3.5.1.2
- HAMAP:   MF_00313
- InterPro:   IPR012338
- InterPro:   IPR015868
- Gene3D:   G3DSA:3.40.710.20
- PANTHER:   PTHR12544
- TIGRFAMs:   TIGR03814

Pfam domain/function: PF04960 Glutaminase; SSF56601 PBP_transp_fold

EC number: =3.5.1.2

Molecular weight: Translated: 35886; Mature: 35886

Theoretical pI: Translated: 5.45; Mature: 5.45

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIKDSSVQVEGQEKVCLDQWVAHYRTYAAKGRSASYIPALGEINVSQLGICIVKPDGTMI
CCCCCCEEECCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHEEEEEECCCCCEE
KSGDWEIPFTLQSISKVIGFIAACLSRGISYVLERVDVEPTGDAFNSIIRLEIHKPGKPF
ECCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHCCEEEEEEECCCCCC
NPMINAGAITIASLLPGTSVQEKLESIYVLIEKMIEKRPAINEIVFQSEWETAHRNRALA
CCCCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCCHHHHHCCCEEE
YYLKENGFLESDVEETLEVYLKQCSIEINTEDIALIGLILAHDGYHPIRKEQVLPKEVAR
EEEECCCCCHHHHHHHHHHHHHHCCEEECCCHHHHHHHHHHCCCCCCHHHHCCCHHHHHH
LTKALMLTCGMYNASGKFAAFIGLPAKSGVSGGIMTLVPSKSRKDLSFQDGCGIGIYGPA
HHHHHHHHHCCCCCCCCEEEEEECCCCCCCCCCEEEEECCCCCCCCCCCCCCCCEEECCC
IDEYGNSLPGIMLLEHIAKEWDLSIF
HHHHCCCCCHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MIKDSSVQVEGQEKVCLDQWVAHYRTYAAKGRSASYIPALGEINVSQLGICIVKPDGTMI
CCCCCCEEECCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHEEEEEECCCCCEE
KSGDWEIPFTLQSISKVIGFIAACLSRGISYVLERVDVEPTGDAFNSIIRLEIHKPGKPF
ECCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHCCEEEEEEECCCCCC
NPMINAGAITIASLLPGTSVQEKLESIYVLIEKMIEKRPAINEIVFQSEWETAHRNRALA
CCCCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCCHHHHHCCCEEE
YYLKENGFLESDVEETLEVYLKQCSIEINTEDIALIGLILAHDGYHPIRKEQVLPKEVAR
EEEECCCCCHHHHHHHHHHHHHHCCEEECCCHHHHHHHHHHCCCCCCHHHHCCCHHHHHH
LTKALMLTCGMYNASGKFAAFIGLPAKSGVSGGIMTLVPSKSRKDLSFQDGCGIGIYGPA
HHHHHHHHHCCCCCCCCEEEEEECCCCCCCCCCEEEEECCCCCCCCCCCCCCCCEEECCC
IDEYGNSLPGIMLLEHIAKEWDLSIF
HHHHCCCCCHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12721629