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The map label for this gene is fexB [H]

Identifier: 227082493

GI number: 227082493

Start: 2462341

End: 2464698

Strand: Reverse

Name: fexB [H]

Synonym: VCM66_2292

Alternate gene names: 227082493

Gene position: 2464698-2462341 (Counterclockwise)

Preceding gene: 227082494

Following gene: 227082491

Centisome position: 85.21

GC content: 46.9

Gene sequence:

>2358_bases
ATGAAACCGATGAAAAATCTCGCCCAGTATTACGTTGATTTGTTAGTCAAATTGGGCATTTTACGTTTCTCCATTCTCTT
AGCTCTCGCCTTGGTTGCTTTGGCTGTGGTGGTACAAGTGGGGATCACGCTGATCCTCAACGGTTTCGTCGATGATATCG
ACATTATCCGCTCGGTATTCTTTGGTTTACTTATCACACCTTGGGCAGTGTACTTTCTTTCTGTGGTGGTTGATCAGCTT
GAAGAGTCACGCCAACGCCTCTCGAAATTGGTGTCTAAACTCAAAGACATGCGTTCGCGCGATCAAGAACTCAATCAAAA
ACTTCAGCAAAACATCGTTAAACTCAATCAAGAAATCGAAGAACGGATCAAGGCAGAAGAGGCACGCGAAGAAGCGATGG
CTGACCTTGAAAATGAAGTGTATCAGCGTGAAAAAACCCAAGTGGAATTGGCCGAACGTACCGCTTTGCTACGCTCTTTC
ATCGACGCATCTCCCGATTTGATCTATTACCGCAACGCCAAAGGTGAGTTTTCTGGCTGCAACCGAGCGATGGAAGAGCT
GACCGGAAAGCGCGAAAGTGAGCTAGTGGGGTTAACGCCTTGGGATGTTTATCGCAAAGAGATTGCTCAATCAATTGTCG
AAACGGATCAGCAAGTTTTTAACAACAACACCGCGATTACTTACGAGCAGTGGTTGGAGTACCCAGATGGTCGTAAGAGC
TTCTTTGAACTGCGTAAAGTGCCTTTTTACAACAAAGATGGCCGCCATCTTGGCTTGGTCGGTTTTGGCCGTGATATCAC
CGAGCGTAAACGCCATGAAGAATCATTGGAGAAAGCCAGCCGCGACAAAACCACGTTTATTTCTACCATTAGCCATGAGC
TGCGCACTCCGCTCAATGGTATCGTTGGTTTGAGCCGGATGCTGCTGGATACTCCATTGAGCGGTGAGCAACGTAAGCAT
TTACAAACCATCAATGTTAGTGCTGTGACGCTGGGTAATATCTTCAACGATATTATTGATATGGATAAGTTTGACCGCCG
TAAATTAGAGCTTTTCCCTGCAGCCCTCAACTTTGAAGAGTTTGTGGCAGAAATTGAAGTGTTGGCGGCCTTAATGGCGG
AGCAAAAAGGGTTACGCTTTGATTTAGAACGGTTAACTGACTTGCCTTCTTTAGTGGAAGTGGACTCGACACGTCTGCGT
CAAGTGTTATGGAACCTACTCAGTAACGCGATGAAGTTCACCAAAGAGGGCGGTGTGGTGATGACGGTCAGCGCAGAATG
CGATGCGCAGCATGCAGAGATCACGATTGAAGTTGAAGATACCGGGATTGGCATTCCGGAAGCGGAACAAGAAAAAATCT
TTGCCATGTATTATCAGGTCAAGTCAGGCAAAGATAACTTACATGCGGTGGGCACTGGCATCGGCTTAGCCGTATCACGT
CAGTTGATTAAGTTGATGGGTGGCGATATCAGCGTCAACAGTGAAGAGGGTTTTGGCAGCACCTTTACCGTAACGATCCG
AGTCCCCTTGTTAGCTGAAGCGCCGATTGAGATTGAGCCACAGGAGCCGCAAACTGAGCTGAATATTTTCATGGTCGAAG
ACATTGAGCTCAATATTACGGTTGCTCGTTCATTACTTGAAAGTATGGGGCATAAGGTGACGGTCGCCATGACGGGCGAA
GAAGCGATCCAAGGCTTTAACCCAACAGAGTACGATCTGGTGTTCCTCGATATTCAGCTACCGGATATGACAGGCTTCGA
TATCGCTCACTATTACCGCACCCATTACTCCTCATTACCGCCATTAGTGGCATTAACTGCCAATGTATTGAAGGATAAAG
AAGAGTATCGCCAAAAAGGGATGGATGCTGCGATAAGCAAGCCTTTATCGGTAGCGGCGGTGCGAGAAGTGATTGCGAAG
ATGACGCAACATCATGCCGGTGAGAGCGTCGCTAAAGTGAAATCAAATAAGGAAAAAGAATTACCAGACGATCTCTATCA
GCAGTTACTGGATCTCGAGATGCTGCAATCCTATGTTGAGATTGTCGGTAGCCAACCCGTGATTGATAGCGTGCACTTAT
TCGAACAATCCATGCCAGCCTATCTTGCTGTATTGGACTCGAATATGGTGGCCAAAGATCAAGAAGGTATTGTCAGTGAA
GCCCATAAAATCAAAGGTGCGGCAGGCTCTGTCGGGTTAAAACGCATTCAAAAGATTGCTCAGAAAGCGCAATCGCCGGA
AGCTCCTGCATGGTGGGAGAACATCAGTGACTGGGTGGAAGAGATCAAAAACGAATATCAGTCTGACATTGCTTTATTGA
AGCGCTGGCTGACTCAGCAAGCAAACGCAAAGCAGTGA

Upstream 100 bases:

>100_bases
GCGGTTCGCCCTGTCACAGCGCCAAGAAGTGGATAAGTGCTGCTAACGTTTGTGTGGGAAAAAGGCTAGACTAAGTGCTC
TTTATCTGACGGAGCAGTGA

Downstream 100 bases:

>100_bases
TAAAAAAAGACCCTAGCCATTGGCTAGGGTCTTCTCTAATTAGATATAAAAGAAGAGGTTAATCTTCTAAATCACCACAG
AAGCGGTAGCCTTCACCGTG

Product: aerobic respiration control sensor protein ArcB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 785; Mature: 785

Protein sequence:

>785_residues
MKPMKNLAQYYVDLLVKLGILRFSILLALALVALAVVVQVGITLILNGFVDDIDIIRSVFFGLLITPWAVYFLSVVVDQL
EESRQRLSKLVSKLKDMRSRDQELNQKLQQNIVKLNQEIEERIKAEEAREEAMADLENEVYQREKTQVELAERTALLRSF
IDASPDLIYYRNAKGEFSGCNRAMEELTGKRESELVGLTPWDVYRKEIAQSIVETDQQVFNNNTAITYEQWLEYPDGRKS
FFELRKVPFYNKDGRHLGLVGFGRDITERKRHEESLEKASRDKTTFISTISHELRTPLNGIVGLSRMLLDTPLSGEQRKH
LQTINVSAVTLGNIFNDIIDMDKFDRRKLELFPAALNFEEFVAEIEVLAALMAEQKGLRFDLERLTDLPSLVEVDSTRLR
QVLWNLLSNAMKFTKEGGVVMTVSAECDAQHAEITIEVEDTGIGIPEAEQEKIFAMYYQVKSGKDNLHAVGTGIGLAVSR
QLIKLMGGDISVNSEEGFGSTFTVTIRVPLLAEAPIEIEPQEPQTELNIFMVEDIELNITVARSLLESMGHKVTVAMTGE
EAIQGFNPTEYDLVFLDIQLPDMTGFDIAHYYRTHYSSLPPLVALTANVLKDKEEYRQKGMDAAISKPLSVAAVREVIAK
MTQHHAGESVAKVKSNKEKELPDDLYQQLLDLEMLQSYVEIVGSQPVIDSVHLFEQSMPAYLAVLDSNMVAKDQEGIVSE
AHKIKGAAGSVGLKRIQKIAQKAQSPEAPAWWENISDWVEEIKNEYQSDIALLKRWLTQQANAKQ

Sequences:

>Translated_785_residues
MKPMKNLAQYYVDLLVKLGILRFSILLALALVALAVVVQVGITLILNGFVDDIDIIRSVFFGLLITPWAVYFLSVVVDQL
EESRQRLSKLVSKLKDMRSRDQELNQKLQQNIVKLNQEIEERIKAEEAREEAMADLENEVYQREKTQVELAERTALLRSF
IDASPDLIYYRNAKGEFSGCNRAMEELTGKRESELVGLTPWDVYRKEIAQSIVETDQQVFNNNTAITYEQWLEYPDGRKS
FFELRKVPFYNKDGRHLGLVGFGRDITERKRHEESLEKASRDKTTFISTISHELRTPLNGIVGLSRMLLDTPLSGEQRKH
LQTINVSAVTLGNIFNDIIDMDKFDRRKLELFPAALNFEEFVAEIEVLAALMAEQKGLRFDLERLTDLPSLVEVDSTRLR
QVLWNLLSNAMKFTKEGGVVMTVSAECDAQHAEITIEVEDTGIGIPEAEQEKIFAMYYQVKSGKDNLHAVGTGIGLAVSR
QLIKLMGGDISVNSEEGFGSTFTVTIRVPLLAEAPIEIEPQEPQTELNIFMVEDIELNITVARSLLESMGHKVTVAMTGE
EAIQGFNPTEYDLVFLDIQLPDMTGFDIAHYYRTHYSSLPPLVALTANVLKDKEEYRQKGMDAAISKPLSVAAVREVIAK
MTQHHAGESVAKVKSNKEKELPDDLYQQLLDLEMLQSYVEIVGSQPVIDSVHLFEQSMPAYLAVLDSNMVAKDQEGIVSE
AHKIKGAAGSVGLKRIQKIAQKAQSPEAPAWWENISDWVEEIKNEYQSDIALLKRWLTQQANAKQ
>Mature_785_residues
MKPMKNLAQYYVDLLVKLGILRFSILLALALVALAVVVQVGITLILNGFVDDIDIIRSVFFGLLITPWAVYFLSVVVDQL
EESRQRLSKLVSKLKDMRSRDQELNQKLQQNIVKLNQEIEERIKAEEAREEAMADLENEVYQREKTQVELAERTALLRSF
IDASPDLIYYRNAKGEFSGCNRAMEELTGKRESELVGLTPWDVYRKEIAQSIVETDQQVFNNNTAITYEQWLEYPDGRKS
FFELRKVPFYNKDGRHLGLVGFGRDITERKRHEESLEKASRDKTTFISTISHELRTPLNGIVGLSRMLLDTPLSGEQRKH
LQTINVSAVTLGNIFNDIIDMDKFDRRKLELFPAALNFEEFVAEIEVLAALMAEQKGLRFDLERLTDLPSLVEVDSTRLR
QVLWNLLSNAMKFTKEGGVVMTVSAECDAQHAEITIEVEDTGIGIPEAEQEKIFAMYYQVKSGKDNLHAVGTGIGLAVSR
QLIKLMGGDISVNSEEGFGSTFTVTIRVPLLAEAPIEIEPQEPQTELNIFMVEDIELNITVARSLLESMGHKVTVAMTGE
EAIQGFNPTEYDLVFLDIQLPDMTGFDIAHYYRTHYSSLPPLVALTANVLKDKEEYRQKGMDAAISKPLSVAAVREVIAK
MTQHHAGESVAKVKSNKEKELPDDLYQQLLDLEMLQSYVEIVGSQPVIDSVHLFEQSMPAYLAVLDSNMVAKDQEGIVSE
AHKIKGAAGSVGLKRIQKIAQKAQSPEAPAWWENISDWVEEIKNEYQSDIALLKRWLTQQANAKQ

Specific function: Member of the two-component regulatory system ArcB/ArcA. Sensor-regulator protein for anaerobic repression of the arc modulon. Activates ArcA via a four-step phosphorelay. ArcB can also dephosphorylate ArcA by a reverse phosphorelay involving His- 717 and

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI48994928, Length=786, Percent_Identity=58.7786259541985, Blast_Score=899, Evalue=0.0,
Organism=Escherichia coli, GI1788713, Length=629, Percent_Identity=27.5039745627981, Blast_Score=203, Evalue=3e-53,
Organism=Escherichia coli, GI87081816, Length=527, Percent_Identity=28.842504743833, Blast_Score=185, Evalue=9e-48,
Organism=Escherichia coli, GI1789149, Length=380, Percent_Identity=31.5789473684211, Blast_Score=178, Evalue=1e-45,
Organism=Escherichia coli, GI145693157, Length=256, Percent_Identity=39.84375, Blast_Score=160, Evalue=3e-40,
Organism=Escherichia coli, GI1788549, Length=378, Percent_Identity=25.9259259259259, Blast_Score=96, Evalue=1e-20,
Organism=Escherichia coli, GI1790436, Length=238, Percent_Identity=28.9915966386555, Blast_Score=94, Evalue=4e-20,
Organism=Escherichia coli, GI1786600, Length=386, Percent_Identity=24.6113989637306, Blast_Score=81, Evalue=3e-16,
Organism=Escherichia coli, GI1786912, Length=230, Percent_Identity=27.8260869565217, Blast_Score=80, Evalue=7e-16,
Organism=Escherichia coli, GI1786783, Length=236, Percent_Identity=25, Blast_Score=74, Evalue=3e-14,
Organism=Escherichia coli, GI1790346, Length=240, Percent_Identity=28.3333333333333, Blast_Score=72, Evalue=2e-13,
Organism=Escherichia coli, GI1790861, Length=216, Percent_Identity=27.3148148148148, Blast_Score=71, Evalue=2e-13,
Organism=Escherichia coli, GI1788393, Length=246, Percent_Identity=25.2032520325203, Blast_Score=71, Evalue=3e-13,
Organism=Escherichia coli, GI87082128, Length=229, Percent_Identity=27.5109170305677, Blast_Score=70, Evalue=5e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR011006
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR008207
- InterPro:   IPR014409
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR001789 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF01627 Hpt; PF00989 PAS; PF00072 Response_reg [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 88649; Mature: 88649

Theoretical pI: Translated: 4.75; Mature: 4.75

Prosite motif: PS50894 HPT ; PS50112 PAS ; PS50113 PAC ; PS50110 RESPONSE_REGULATORY ; PS00445 FGGY_KINASES_2 ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKPMKNLAQYYVDLLVKLGILRFSILLALALVALAVVVQVGITLILNGFVDDIDIIRSVF
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FGLLITPWAVYFLSVVVDQLEESRQRLSKLVSKLKDMRSRDQELNQKLQQNIVKLNQEIE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ERIKAEEAREEAMADLENEVYQREKTQVELAERTALLRSFIDASPDLIYYRNAKGEFSGC
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCHHH
NRAMEELTGKRESELVGLTPWDVYRKEIAQSIVETDQQVFNNNTAITYEQWLEYPDGRKS
HHHHHHHCCCCCCCEECCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEHHHHHCCCCCHHH
FFELRKVPFYNKDGRHLGLVGFGRDITERKRHEESLEKASRDKTTFISTISHELRTPLNG
HHHHHHCCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCHHH
IVGLSRMLLDTPLSGEQRKHLQTINVSAVTLGNIFNDIIDMDKFDRRKLELFPAALNFEE
HHHHHHHHHCCCCCCHHHHHHHHHCHHHHHHHHHHHHHHCCCHHCCHHHHHHHHHCCHHH
FVAEIEVLAALMAEQKGLRFDLERLTDLPSLVEVDSTRLRQVLWNLLSNAMKFTKEGGVV
HHHHHHHHHHHHHHHCCCEEEHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEE
MTVSAECDAQHAEITIEVEDTGIGIPEAEQEKIFAMYYQVKSGKDNLHAVGTGIGLAVSR
EEEECCCCCCCCEEEEEEECCCCCCCCCHHHHHHHHHHHHHCCCCCCEEHHCHHHHHHHH
QLIKLMGGDISVNSEEGFGSTFTVTIRVPLLAEAPIEIEPQEPQTELNIFMVEDIELNIT
HHHHHHCCCEEECCCCCCCCEEEEEEEEEEEECCCCCCCCCCCCCCEEEEEEECCEEHHH
VARSLLESMGHKVTVAMTGEEAIQGFNPTEYDLVFLDIQLPDMTGFDIAHYYRTHYSSLP
HHHHHHHHCCCEEEEEECCHHHHCCCCCCCEEEEEEEEECCCCCCCHHHHHHHHHHCCCC
PLVALTANVLKDKEEYRQKGMDAAISKPLSVAAVREVIAKMTQHHAGESVAKVKSNKEKE
HHHHHHHHHHHHHHHHHHCCCCHHHCCCHHHHHHHHHHHHHHHHHCCHHHHHHHCCCCCC
LPDDLYQQLLDLEMLQSYVEIVGSQPVIDSVHLFEQSMPAYLAVLDSNMVAKDQEGIVSE
CCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCHHHHHHCCCCCCCCHHHHHHH
AHKIKGAAGSVGLKRIQKIAQKAQSPEAPAWWENISDWVEEIKNEYQSDIALLKRWLTQQ
HHHHCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
ANAKQ
CCCCC
>Mature Secondary Structure
MKPMKNLAQYYVDLLVKLGILRFSILLALALVALAVVVQVGITLILNGFVDDIDIIRSVF
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FGLLITPWAVYFLSVVVDQLEESRQRLSKLVSKLKDMRSRDQELNQKLQQNIVKLNQEIE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ERIKAEEAREEAMADLENEVYQREKTQVELAERTALLRSFIDASPDLIYYRNAKGEFSGC
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCHHH
NRAMEELTGKRESELVGLTPWDVYRKEIAQSIVETDQQVFNNNTAITYEQWLEYPDGRKS
HHHHHHHCCCCCCCEECCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEHHHHHCCCCCHHH
FFELRKVPFYNKDGRHLGLVGFGRDITERKRHEESLEKASRDKTTFISTISHELRTPLNG
HHHHHHCCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCHHH
IVGLSRMLLDTPLSGEQRKHLQTINVSAVTLGNIFNDIIDMDKFDRRKLELFPAALNFEE
HHHHHHHHHCCCCCCHHHHHHHHHCHHHHHHHHHHHHHHCCCHHCCHHHHHHHHHCCHHH
FVAEIEVLAALMAEQKGLRFDLERLTDLPSLVEVDSTRLRQVLWNLLSNAMKFTKEGGVV
HHHHHHHHHHHHHHHCCCEEEHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEE
MTVSAECDAQHAEITIEVEDTGIGIPEAEQEKIFAMYYQVKSGKDNLHAVGTGIGLAVSR
EEEECCCCCCCCEEEEEEECCCCCCCCCHHHHHHHHHHHHHCCCCCCEEHHCHHHHHHHH
QLIKLMGGDISVNSEEGFGSTFTVTIRVPLLAEAPIEIEPQEPQTELNIFMVEDIELNIT
HHHHHHCCCEEECCCCCCCCEEEEEEEEEEEECCCCCCCCCCCCCCEEEEEEECCEEHHH
VARSLLESMGHKVTVAMTGEEAIQGFNPTEYDLVFLDIQLPDMTGFDIAHYYRTHYSSLP
HHHHHHHHCCCEEEEEECCHHHHCCCCCCCEEEEEEEEECCCCCCCHHHHHHHHHHCCCC
PLVALTANVLKDKEEYRQKGMDAAISKPLSVAAVREVIAKMTQHHAGESVAKVKSNKEKE
HHHHHHHHHHHHHHHHHHCCCCHHHCCCHHHHHHHHHHHHHHHHHCCHHHHHHHCCCCCC
LPDDLYQQLLDLEMLQSYVEIVGSQPVIDSVHLFEQSMPAYLAVLDSNMVAKDQEGIVSE
CCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCHHHHHHCCCCCCCCHHHHHHH
AHKIKGAAGSVGLKRIQKIAQKAQSPEAPAWWENISDWVEEIKNEYQSDIALLKRWLTQQ
HHHHCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
ANAKQ
CCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]