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The map label for this gene is recD [H]

Identifier: 227082443

GI number: 227082443

Start: 2403529

End: 2405649

Strand: Reverse

Name: recD [H]

Synonym: VCM66_2242

Alternate gene names: 227082443

Gene position: 2405649-2403529 (Counterclockwise)

Preceding gene: 227082444

Following gene: 227082441

Centisome position: 83.17

GC content: 52.52

Gene sequence:

>2121_bases
ATGATGTTTTGGGATAGCGAAGTAGCGAAACGTCTGCTGGCACAAGGCGCGCTGCGTCCTTTGGATGTGCAGTTTGCCCG
CTTTATTGGCAAGCAAGCCGTATTGGCAGGGCACAACGCTGCAGAAAGTGAGCTTTTGAGTGTACTGAGCGCGGCGCTCA
GTGCAGAACTTGGGCGTGGACACATCTGTCTGCCACTGTGTGATGCACAGGGTAATCGTTGCGATCTAGCGGCGCTGATT
GGTCTTTATGGTGAAGCGAGTTTGCAGCACAGTGAACGCTGGTTAGCGGTAGACTGGCAAGCCTTACTGCAAGCCTCGCC
GTTGGTGGGGCAGCAAGGTGAAGCGGTGCCGTTAATGTTTGATGGCTCAAGGCTCTATCTGCATCGCTACTGGCATTATG
AAAAGCAACTGGCGGCGCGATTGACTGAGTTGGCCGCACCCCAACGTTTAAGCCCTGCTGAACTGGCTAACTTGCGTGAA
CGCCTGAATACCTTATTTGCCCGCGACTATTTAGGCTTGTGGCAAGCACTACAACAAAAGCCGCTAAGTTCGGTCGAGCG
GATTCAACTGCTGAATGATCGATTGGATGTTGTGGAGTCGGATGCGCTGGATTGGCCAGCGATTGAAGCTGTAGTCGAAA
AAGCGCAGCGTGCCGCGGATTTGCAAGCTTTAGAGCAGCTTATTCCGCTTACTCACTGCTTAAACTGGCAAAAAGTGGCG
GCCGCTGTCGCTCTTACCCGCCGTTTTGCGGTGATTTCCGGTGGGCCGGGAACCGGCAAAACCACCACAGTGACCAAGCT
TCTGGCGGCGCTGATTAGCCAAAGCATGGCGCAAGGTAAAGTGCCAGAGATCAAATTGATCGCTCCAACCGGTAAAGCCG
CGGCACGGTTAACCGAATCGATGGGTAAAGCGGTGAGTCAGCTGGCGATAGAGCCTGAGATCGCCGCGGCGATCCCGAGC
TCTTCCAGCACCATTCACCGTTTGCTTGGCGCGATTCCGGGCAGCGCTGAGTTTCGTCATCATACACGTAATCCACTCCA
TCTTGATCTGTTGGTGGTGGATGAAGCGTCCATGGTTGACTTGCCTTTGATGGTGAAACTGGTCGAAGCGCTACCCAAGC
ACGCTCGGTTGATTTTGCTCGGCGATAAAGATCAATTGGCTTCGGTGGAAGCGGGGGCGGTGCTCGGTGATATTTGTACC
TTCCTGAACCAAGGTTACGGCCATGAGCAGGGCGCGCAGTTGGCTGAACTGACGGGGTTTGCCACTCTGCGCCAAACTGC
CAGTAAAACGGTAAACCCGGTGGCGGATTGCTTATGTATGCTGCAAAAAAGCTACCGTTTTGATGCGCGATCTGGCATTG
GTCAATTGGCGAAAGCGATCAACAGTGGATCTCCGGCGCGCGTTGAAGCGGTGTGGCAACAGTCGTTCAGCGATATTGAA
CACTTTGCCCTTAGTGGTGAGCATTATCAGCAACTGCTGCAAACCTTAGTGCAGGCTTATCGTCCTTATCTGAGCTTGCT
TAATCAGCCAACTGAGCAATTTGAGTCGACCCAACAAAGCATGCTCACACTTGCCAAATCAGCACTTGATGCGTTCAGTC
GCTGCCGATTGCTCTGTGCGCTGCGTGAAGGCGATTTTGGAGTGATGGGGCTGAACACTCGCATCGAACGGGCGTTGAAT
GCTCACAAGCTGATTAAAACGCAAGAAGAGATCTGGTATCACGGGCGGCCGATCATGGTCACGCGTAACGATCATGGTTT
GGGGTTATACAATGGCGATATTGGCTTGTGTATGCGCGATCGTGACGATGATCAGGGCAGACTGAAAGTCTATTTTGAGT
TGCCGGATGGCAGCATTAAAGCCGTGTTGCCGAGCCGAGTCCCGCAACATGAAACCGCGTATGCGATGACCATACATAAA
TCGCAAGGCAGCGAATTTGATTTAACTTTGCTGATTTTACCGCCGGATTACAGTCCGATTCTGACGCGTGAGTTAGTTTA
CACGGGGATCACAAGGGCGAAAAAACAGCTCAAATTGTATTGCGATAACAAGGTATTGCAGCGAGCAATTAAAGTGAAAA
CCCAACGGGCGAGTGGCTTAGTGGCAAGGTTGGAGCAGTAA

Upstream 100 bases:

>100_bases
CCAAGCCAAGTTTGGCCTTGTTAGATGAGTTGGATGGATTGATTGCAGGGCGTGAGTTGGCGCAAAGAGCGAGTAAAGCT
GGGCAGATGGAGCTTGATTT

Downstream 100 bases:

>100_bases
ATGCTCCGCCATTCCGTGGCGGCACAGCATTAAAGGTTGGCAAAAGCTTTAGTAAAGGTGATGCTGCGGATCTGGTAACG
TTCACGCGATTGGAGCAGAA

Product: exodeoxyribonuclease V, 67 kDa subunit

Products: NA

Alternate protein names: Exodeoxyribonuclease V 67 kDa polypeptide [H]

Number of amino acids: Translated: 706; Mature: 706

Protein sequence:

>706_residues
MMFWDSEVAKRLLAQGALRPLDVQFARFIGKQAVLAGHNAAESELLSVLSAALSAELGRGHICLPLCDAQGNRCDLAALI
GLYGEASLQHSERWLAVDWQALLQASPLVGQQGEAVPLMFDGSRLYLHRYWHYEKQLAARLTELAAPQRLSPAELANLRE
RLNTLFARDYLGLWQALQQKPLSSVERIQLLNDRLDVVESDALDWPAIEAVVEKAQRAADLQALEQLIPLTHCLNWQKVA
AAVALTRRFAVISGGPGTGKTTTVTKLLAALISQSMAQGKVPEIKLIAPTGKAAARLTESMGKAVSQLAIEPEIAAAIPS
SSSTIHRLLGAIPGSAEFRHHTRNPLHLDLLVVDEASMVDLPLMVKLVEALPKHARLILLGDKDQLASVEAGAVLGDICT
FLNQGYGHEQGAQLAELTGFATLRQTASKTVNPVADCLCMLQKSYRFDARSGIGQLAKAINSGSPARVEAVWQQSFSDIE
HFALSGEHYQQLLQTLVQAYRPYLSLLNQPTEQFESTQQSMLTLAKSALDAFSRCRLLCALREGDFGVMGLNTRIERALN
AHKLIKTQEEIWYHGRPIMVTRNDHGLGLYNGDIGLCMRDRDDDQGRLKVYFELPDGSIKAVLPSRVPQHETAYAMTIHK
SQGSEFDLTLLILPPDYSPILTRELVYTGITRAKKQLKLYCDNKVLQRAIKVKTQRASGLVARLEQ

Sequences:

>Translated_706_residues
MMFWDSEVAKRLLAQGALRPLDVQFARFIGKQAVLAGHNAAESELLSVLSAALSAELGRGHICLPLCDAQGNRCDLAALI
GLYGEASLQHSERWLAVDWQALLQASPLVGQQGEAVPLMFDGSRLYLHRYWHYEKQLAARLTELAAPQRLSPAELANLRE
RLNTLFARDYLGLWQALQQKPLSSVERIQLLNDRLDVVESDALDWPAIEAVVEKAQRAADLQALEQLIPLTHCLNWQKVA
AAVALTRRFAVISGGPGTGKTTTVTKLLAALISQSMAQGKVPEIKLIAPTGKAAARLTESMGKAVSQLAIEPEIAAAIPS
SSSTIHRLLGAIPGSAEFRHHTRNPLHLDLLVVDEASMVDLPLMVKLVEALPKHARLILLGDKDQLASVEAGAVLGDICT
FLNQGYGHEQGAQLAELTGFATLRQTASKTVNPVADCLCMLQKSYRFDARSGIGQLAKAINSGSPARVEAVWQQSFSDIE
HFALSGEHYQQLLQTLVQAYRPYLSLLNQPTEQFESTQQSMLTLAKSALDAFSRCRLLCALREGDFGVMGLNTRIERALN
AHKLIKTQEEIWYHGRPIMVTRNDHGLGLYNGDIGLCMRDRDDDQGRLKVYFELPDGSIKAVLPSRVPQHETAYAMTIHK
SQGSEFDLTLLILPPDYSPILTRELVYTGITRAKKQLKLYCDNKVLQRAIKVKTQRASGLVARLEQ
>Mature_706_residues
MMFWDSEVAKRLLAQGALRPLDVQFARFIGKQAVLAGHNAAESELLSVLSAALSAELGRGHICLPLCDAQGNRCDLAALI
GLYGEASLQHSERWLAVDWQALLQASPLVGQQGEAVPLMFDGSRLYLHRYWHYEKQLAARLTELAAPQRLSPAELANLRE
RLNTLFARDYLGLWQALQQKPLSSVERIQLLNDRLDVVESDALDWPAIEAVVEKAQRAADLQALEQLIPLTHCLNWQKVA
AAVALTRRFAVISGGPGTGKTTTVTKLLAALISQSMAQGKVPEIKLIAPTGKAAARLTESMGKAVSQLAIEPEIAAAIPS
SSSTIHRLLGAIPGSAEFRHHTRNPLHLDLLVVDEASMVDLPLMVKLVEALPKHARLILLGDKDQLASVEAGAVLGDICT
FLNQGYGHEQGAQLAELTGFATLRQTASKTVNPVADCLCMLQKSYRFDARSGIGQLAKAINSGSPARVEAVWQQSFSDIE
HFALSGEHYQQLLQTLVQAYRPYLSLLNQPTEQFESTQQSMLTLAKSALDAFSRCRLLCALREGDFGVMGLNTRIERALN
AHKLIKTQEEIWYHGRPIMVTRNDHGLGLYNGDIGLCMRDRDDDQGRLKVYFELPDGSIKAVLPSRVPQHETAYAMTIHK
SQGSEFDLTLLILPPDYSPILTRELVYTGITRAKKQLKLYCDNKVLQRAIKVKTQRASGLVARLEQ

Specific function: Exhibits several catalytic activities, including ATP- dependent exonuclease, ATP-stimulated endonuclease, ATP-dependent unwinding and DNA-dependent ATPase activities. Strand cleavage occurs 5' to 3' during the unwinding of duplex DNA at CHI sequences, whi

COG id: COG0507

COG function: function code L; ATP-dependent exoDNAse (exonuclease V), alpha subunit - helicase superfamily I member

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the recD family [H]

Homologues:

Organism=Escherichia coli, GI1789182, Length=690, Percent_Identity=46.231884057971, Blast_Score=507, Evalue=1e-144,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR007807
- InterPro:   IPR006344
- InterPro:   IPR000606 [H]

Pfam domain/function: PF05127 DUF699; PF01443 Viral_helicase1 [H]

EC number: =3.1.11.5 [H]

Molecular weight: Translated: 77735; Mature: 77735

Theoretical pI: Translated: 7.77; Mature: 7.77

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMFWDSEVAKRLLAQGALRPLDVQFARFIGKQAVLAGHNAAESELLSVLSAALSAELGRG
CCCCCHHHHHHHHHHCCCCCCHHHHHHHHCCHHHCCCCCCHHHHHHHHHHHHHHHHCCCC
HICLPLCDAQGNRCDLAALIGLYGEASLQHSERWLAVDWQALLQASPLVGQQGEAVPLMF
CEEEEEECCCCCCCHHHHHHHHHCCCHHHCCCCEEEEEHHHHHCCCCCCCCCCCEEEEEE
DGSRLYLHRYWHYEKQLAARLTELAAPQRLSPAELANLRERLNTLFARDYLGLWQALQQK
CCCEEEEHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
PLSSVERIQLLNDRLDVVESDALDWPAIEAVVEKAQRAADLQALEQLIPLTHCLNWQKVA
CHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHH
AAVALTRRFAVISGGPGTGKTTTVTKLLAALISQSMAQGKVPEIKLIAPTGKAAARLTES
HHHHHHHHHEEEECCCCCCCHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHH
MGKAVSQLAIEPEIAAAIPSSSSTIHRLLGAIPGSAEFRHHTRNPLHLDLLVVDEASMVD
HHHHHHHHHCCCHHHHCCCCCCHHHHHHHHCCCCCCHHHHCCCCCEEEEEEEECCCCCCC
LPLMVKLVEALPKHARLILLGDKDQLASVEAGAVLGDICTFLNQGYGHEQGAQLAELTGF
HHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHH
ATLRQTASKTVNPVADCLCMLQKSYRFDARSGIGQLAKAINSGSPARVEAVWQQSFSDIE
HHHHHHHHHHHHHHHHHHHHHHHHCCCCHHCCHHHHHHHHCCCCCHHHHHHHHHHHHHHH
HFALSGEHYQQLLQTLVQAYRPYLSLLNQPTEQFESTQQSMLTLAKSALDAFSRCRLLCA
HHHCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LREGDFGVMGLNTRIERALNAHKLIKTQEEIWYHGRPIMVTRNDHGLGLYNGDIGLCMRD
EECCCEEEEECCHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCEEEECCEEEEEEC
RDDDQGRLKVYFELPDGSIKAVLPSRVPQHETAYAMTIHKSQGSEFDLTLLILPPDYSPI
CCCCCCEEEEEEECCCCCEEEECCCCCCCCCCEEEEEEECCCCCCEEEEEEEECCCCCHH
LTRELVYTGITRAKKQLKLYCDNKVLQRAIKVKTQRASGLVARLEQ
HHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MMFWDSEVAKRLLAQGALRPLDVQFARFIGKQAVLAGHNAAESELLSVLSAALSAELGRG
CCCCCHHHHHHHHHHCCCCCCHHHHHHHHCCHHHCCCCCCHHHHHHHHHHHHHHHHCCCC
HICLPLCDAQGNRCDLAALIGLYGEASLQHSERWLAVDWQALLQASPLVGQQGEAVPLMF
CEEEEEECCCCCCCHHHHHHHHHCCCHHHCCCCEEEEEHHHHHCCCCCCCCCCCEEEEEE
DGSRLYLHRYWHYEKQLAARLTELAAPQRLSPAELANLRERLNTLFARDYLGLWQALQQK
CCCEEEEHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
PLSSVERIQLLNDRLDVVESDALDWPAIEAVVEKAQRAADLQALEQLIPLTHCLNWQKVA
CHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHH
AAVALTRRFAVISGGPGTGKTTTVTKLLAALISQSMAQGKVPEIKLIAPTGKAAARLTES
HHHHHHHHHEEEECCCCCCCHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHH
MGKAVSQLAIEPEIAAAIPSSSSTIHRLLGAIPGSAEFRHHTRNPLHLDLLVVDEASMVD
HHHHHHHHHCCCHHHHCCCCCCHHHHHHHHCCCCCCHHHHCCCCCEEEEEEEECCCCCCC
LPLMVKLVEALPKHARLILLGDKDQLASVEAGAVLGDICTFLNQGYGHEQGAQLAELTGF
HHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHH
ATLRQTASKTVNPVADCLCMLQKSYRFDARSGIGQLAKAINSGSPARVEAVWQQSFSDIE
HHHHHHHHHHHHHHHHHHHHHHHHCCCCHHCCHHHHHHHHCCCCCHHHHHHHHHHHHHHH
HFALSGEHYQQLLQTLVQAYRPYLSLLNQPTEQFESTQQSMLTLAKSALDAFSRCRLLCA
HHHCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LREGDFGVMGLNTRIERALNAHKLIKTQEEIWYHGRPIMVTRNDHGLGLYNGDIGLCMRD
EECCCEEEEECCHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCEEEECCEEEEEEC
RDDDQGRLKVYFELPDGSIKAVLPSRVPQHETAYAMTIHKSQGSEFDLTLLILPPDYSPI
CCCCCCEEEEEEECCCCCEEEECCCCCCCCCCEEEEEEECCCCCCEEEEEEEECCCCCHH
LTRELVYTGITRAKKQLKLYCDNKVLQRAIKVKTQRASGLVARLEQ
HHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 3537961; 9278503; 3537960 [H]